MX2019012508A - Metodo para preparar una composicion con un bajo contenido de oxigeno disuelto, que comprende paracetamol, y opcionalmente uno o mas aine, y una composicion obtenida de la misma. - Google Patents

Metodo para preparar una composicion con un bajo contenido de oxigeno disuelto, que comprende paracetamol, y opcionalmente uno o mas aine, y una composicion obtenida de la misma.

Info

Publication number
MX2019012508A
MX2019012508A MX2019012508A MX2019012508A MX2019012508A MX 2019012508 A MX2019012508 A MX 2019012508A MX 2019012508 A MX2019012508 A MX 2019012508A MX 2019012508 A MX2019012508 A MX 2019012508A MX 2019012508 A MX2019012508 A MX 2019012508A
Authority
MX
Mexico
Prior art keywords
acetaminophen
composition
nsaids
optionally
preparing
Prior art date
Application number
MX2019012508A
Other languages
English (en)
Inventor
Jacobsen Thomas
Original Assignee
Hyloris Dev Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=58645031&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2019012508(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hyloris Dev Sa filed Critical Hyloris Dev Sa
Publication of MX2019012508A publication Critical patent/MX2019012508A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención proporciona un método para preparar una composición acuosa para administración intravenosa que comprende paracetamol, y opcionalmente uno o más fármacos antiinflamatorios no esteroides (AINE), por lo cual el oxígeno disuelto de la composición en un recipiente cerrado es de 1,0 ppm como máximo, caracterizado dicho método porque comprende enjuagar por lo menos una vez un recipiente para la producción del compuesto con agua de una temperatura de por lo menos 80°C, calentando de este modo el recipiente y creando un entorno de bajo contenido de oxígeno en dicho recipiente; y en dicho recipiente enjuagado disolver paracetamol en agua par inyectables, donde dicha agua para inyectables está a una temperatura de por lo menos 80°C, por medio de lo cual opcionalmente uno o más AINE se agregan antes de o después de disolver el paracetamol.
MX2019012508A 2017-04-20 2018-04-20 Metodo para preparar una composicion con un bajo contenido de oxigeno disuelto, que comprende paracetamol, y opcionalmente uno o mas aine, y una composicion obtenida de la misma. MX2019012508A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2017/059440 WO2018192664A1 (en) 2017-04-20 2017-04-20 METHOD FOR PREPARING A COMPOSITION WITH A LOW DISSOLVED OXYGEN CONTENT, COMPRISING ACETAMINOPHEN, AND OPTIONALLY ONE OR MORE NSAIDs, AND A COMPOSITION OBTAINED THEREOF
PCT/EP2018/060205 WO2018193099A1 (en) 2017-04-20 2018-04-20 METHOD FOR PREPARING A COMPOSITION WITH A LOW DISSOLVED OXYGEN CONTENT, COMPRISING ACETAMINOPHEN, AND OPTIONALLY ONE OR MORE NSAIDs, AND A COMPOSITION OBTAINED THEREOF

Publications (1)

Publication Number Publication Date
MX2019012508A true MX2019012508A (es) 2020-02-05

Family

ID=58645031

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019012508A MX2019012508A (es) 2017-04-20 2018-04-20 Metodo para preparar una composicion con un bajo contenido de oxigeno disuelto, que comprende paracetamol, y opcionalmente uno o mas aine, y una composicion obtenida de la misma.

Country Status (20)

Country Link
US (1) US11413241B2 (es)
EP (1) EP3612157A1 (es)
JP (1) JP6944590B2 (es)
KR (2) KR102625301B1 (es)
CN (1) CN110719773A (es)
AR (1) AR111484A1 (es)
AU (1) AU2018255376B2 (es)
CA (1) CA3060325A1 (es)
CL (1) CL2019002985A1 (es)
CO (1) CO2019011569A2 (es)
EC (1) ECSP19075614A (es)
IL (1) IL270035B2 (es)
MX (1) MX2019012508A (es)
PE (1) PE20191793A1 (es)
PH (1) PH12019502385A1 (es)
RU (1) RU2019137019A (es)
SA (1) SA519410340B1 (es)
SG (1) SG11201909726YA (es)
TW (1) TW201841632A (es)
WO (2) WO2018192664A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016008546A1 (en) 2014-07-18 2016-01-21 Everbright Pharmaceuticals S.A.R.L. Aqueous formulation comprising paracetamol and ibuprofen
UY38573A (es) * 2019-03-05 2020-09-30 Grifols Worldwide Operations Ltd Procedimiento de preparación de contenedores de productos hemoderivados
CN115040475A (zh) * 2022-06-23 2022-09-13 杭州浙中医药科技有限公司 一种n-乙酰半胱氨酸口服溶液

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2751875B1 (fr) 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
FR2809619B1 (fr) * 2000-06-06 2004-09-24 Pharmatop Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention
US20060100578A1 (en) 2004-09-13 2006-05-11 Tandem Medical, Inc. Medication delivery apparatus and methods for intravenous infusions
KR20110065417A (ko) 2008-01-03 2011-06-15 욱크하르트 리미티드 파라세타몰 및 이부프로펜을 포함하는 경구 약제학적 현탁액
KR20110112279A (ko) 2008-10-14 2011-10-12 에이에프티 파마슈티칼스 리미티드 의약품 및 치료
EP2243477A1 (de) 2009-04-22 2010-10-27 Fresenius Kabi Deutschland GmbH Paracetamol zur parenteralen Verabreichung
US8404748B2 (en) 2009-08-13 2013-03-26 Neogen N.V. Storage-stable formulation of paracetamol in aqueous solution
ES2403121T3 (es) 2010-05-19 2013-05-14 Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. Formulación de paracetamol inyectable, estable, lista para usar
HUE045442T2 (hu) 2010-11-04 2019-12-30 Aft Pharmaceuticals Ltd Kombinációs készítmény
US9205037B2 (en) 2011-07-20 2015-12-08 Church & Dwight Co., Inc. Single phase depilatory composition
ES2414557B1 (es) * 2012-01-16 2014-06-10 Novocat Farma, S.A. Composición acuosa de paracetamol para inyección
BE1020614A5 (nl) 2012-01-27 2014-01-07 Hubert De Backer Nv Injectiespuit.
US9072661B2 (en) 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
CA2867477C (en) 2012-03-16 2017-09-26 Cumberland Pharmaceuticals, Inc. Injectable ibuprofen formulation
WO2016008546A1 (en) 2014-07-18 2016-01-21 Everbright Pharmaceuticals S.A.R.L. Aqueous formulation comprising paracetamol and ibuprofen

Also Published As

Publication number Publication date
TW201841632A (zh) 2018-12-01
CA3060325A1 (en) 2018-10-25
IL270035B2 (en) 2023-05-01
PE20191793A1 (es) 2019-12-24
CL2019002985A1 (es) 2020-01-31
SG11201909726YA (en) 2019-11-28
WO2018193099A1 (en) 2018-10-25
CO2019011569A2 (es) 2021-03-08
JP6944590B2 (ja) 2021-10-06
ECSP19075614A (es) 2019-11-30
JP2020522564A (ja) 2020-07-30
IL270035B1 (en) 2023-01-01
RU2019137019A3 (es) 2021-07-05
AU2018255376A1 (en) 2019-11-07
AU2018255376B2 (en) 2023-07-06
KR20230160413A (ko) 2023-11-23
KR102625301B1 (ko) 2024-01-15
US20210338578A1 (en) 2021-11-04
KR20190137859A (ko) 2019-12-11
SA519410340B1 (ar) 2022-03-13
WO2018192664A1 (en) 2018-10-25
EP3612157A1 (en) 2020-02-26
US11413241B2 (en) 2022-08-16
CN110719773A (zh) 2020-01-21
AR111484A1 (es) 2019-07-17
RU2019137019A (ru) 2021-05-20
IL270035A (es) 2019-12-31
PH12019502385A1 (en) 2020-09-14

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