MX2019012101A - Vacuna contra vhb. - Google Patents

Vacuna contra vhb.

Info

Publication number
MX2019012101A
MX2019012101A MX2019012101A MX2019012101A MX2019012101A MX 2019012101 A MX2019012101 A MX 2019012101A MX 2019012101 A MX2019012101 A MX 2019012101A MX 2019012101 A MX2019012101 A MX 2019012101A MX 2019012101 A MX2019012101 A MX 2019012101A
Authority
MX
Mexico
Prior art keywords
hbv
polymerase
pmut
hbsag
surface antigen
Prior art date
Application number
MX2019012101A
Other languages
English (en)
Spanish (es)
Inventor
BARNES Eleanor
Chinnakannan Senthil
Original Assignee
Univ Oxford Innovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Oxford Innovation Ltd filed Critical Univ Oxford Innovation Ltd
Publication of MX2019012101A publication Critical patent/MX2019012101A/es

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • C12N9/1276RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C12Y207/07Nucleotidyltransferases (2.7.7)
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    • C12Y301/26Endoribonucleases producing 5'-phosphomonoesters (3.1.26)
    • C12Y301/26004Ribonuclease H (3.1.26.4)
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    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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    • C07K2319/00Fusion polypeptide
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    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
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    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2730/00Reverse transcribing DNA viruses
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    • C12N2730/10011Hepadnaviridae
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    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
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    • C12N2800/00Nucleic acids vectors
    • C12N2800/10Plasmid DNA
    • C12N2800/106Plasmid DNA for vertebrates
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  • Health & Medical Sciences (AREA)
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  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
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  • Biochemistry (AREA)
  • Biotechnology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2019012101A 2017-04-10 2018-04-10 Vacuna contra vhb. MX2019012101A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1705765.4A GB201705765D0 (en) 2017-04-10 2017-04-10 HBV vaccine
PCT/GB2018/050948 WO2018189522A1 (en) 2017-04-10 2018-04-10 Hbv vaccine

Publications (1)

Publication Number Publication Date
MX2019012101A true MX2019012101A (es) 2019-12-11

Family

ID=58744773

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019012101A MX2019012101A (es) 2017-04-10 2018-04-10 Vacuna contra vhb.

Country Status (15)

Country Link
US (2) US20200113998A1 (https=)
EP (1) EP3609535B1 (https=)
JP (1) JP7326157B2 (https=)
KR (1) KR102700586B1 (https=)
CN (2) CN118576699A (https=)
AU (1) AU2018251241B2 (https=)
CA (1) CA3059290A1 (https=)
DK (1) DK3609535T3 (https=)
ES (1) ES3036962T3 (https=)
GB (1) GB201705765D0 (https=)
MX (1) MX2019012101A (https=)
MY (1) MY202396A (https=)
PH (1) PH12019502310A1 (https=)
SG (1) SG11201909353VA (https=)
WO (1) WO2018189522A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11389531B2 (en) 2017-12-19 2022-07-19 Janssen Sciences Ireland Unlimited Company Methods and apparatus for the delivery of hepatitis B virus (HBV) vaccines
EA202091513A1 (ru) 2017-12-19 2020-09-09 Янссен Сайенсиз Айрлэнд Анлимитед Компани Вакцины против вируса гепатита b (hbv) и их применение
US11020476B2 (en) 2017-12-19 2021-06-01 Janssen Sciences Ireland Unlimited Company Methods and compositions for inducing an immune response against Hepatitis B Virus (HBV)
TW202102256A (zh) * 2019-03-05 2021-01-16 比利時商葛蘭素史密斯克藍生物品公司 B型肝炎免疫法及組合物
CA3143679A1 (en) * 2019-06-18 2020-12-24 Janssen Sciences Ireland Unlimited Company Combination of hepatitis b virus (hbv) vaccines and hbv-targeting rnai
US20220313815A1 (en) * 2019-06-20 2022-10-06 Janssen Sciences Ireland Unlimited Company Self-replicating rna molecules for hepatitis b virus (hbv) vaccines and uses thereof
EP4021923A1 (en) 2019-08-29 2022-07-06 VIR Biotechnology, Inc. Hepatitis b virus vaccines
CN119770638A (zh) 2019-09-30 2025-04-08 吉利德科学公司 Hbv疫苗和治疗hbv的方法
WO2021243149A2 (en) * 2020-05-28 2021-12-02 President And Fellows Of Harvard College Protein covariance networks reveal interactions important to the emergence of sars coronaviruses as human pathogens
CN116367854A (zh) * 2020-07-08 2023-06-30 杨森科学爱尔兰无限公司 针对hbv的rna复制子疫苗
TW202229556A (zh) 2020-10-02 2022-08-01 國立大學法人大阪大學 針對SARS-CoV-2之改良型DNA疫苗
TW202245809A (zh) * 2020-12-18 2022-12-01 美商詹森藥物公司 用於治療b型肝炎病毒感染之組合療法
CN115595312A (zh) * 2021-06-28 2023-01-13 中国农业大学(Cn) 一种重组腺病毒及其应用
WO2023086961A1 (en) * 2021-11-12 2023-05-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Sars-cov-2 spike fused to a hepatitis b surface antigen
EP4444347A1 (en) 2021-12-07 2024-10-16 Barinthus Biotherapeutics (UK) Limited Vaccine boost methods and compositions
EP4680277A1 (en) * 2023-03-17 2026-01-21 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Hbv antigen formulation for treating hepatitis b
GB202317925D0 (en) 2023-11-23 2024-01-10 Spybiotech Ltd Vaccines
CN118593695B (zh) * 2024-08-07 2024-10-22 山东兴瑞生物科技有限公司 一种用于治疗HBV感染的siRNA和mRNA联合疫苗

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5679394A (en) 1992-11-25 1994-06-22 International Biotechnology Laboratories, Inc. Hepatitis b virus vaccines
WO2005017149A1 (en) * 2003-06-03 2005-02-24 Cell Genesys, Inc. Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
WO2008020656A1 (en) * 2006-08-14 2008-02-21 Postech Foundation A dna vaccine for curing chronic hepatitis b and a method of preparing same
US10076570B2 (en) 2009-08-07 2018-09-18 Transgene S.A. Composition for treating HBV infection
TWI555531B (zh) 2009-08-07 2016-11-01 傳斯堅公司 用以治療b型肝炎病毒(hbv)感染之組成物
EA028659B1 (ru) 2011-02-12 2017-12-29 Глоубиммьюн, Инк. Терапевтическое средство на основе дрожжей для лечения хронического гепатита b
TWI623618B (zh) * 2011-07-12 2018-05-11 傳斯堅公司 Hbv聚合酶突變體
CN103173492B (zh) * 2013-03-12 2014-08-13 中国人民解放军白求恩国际和平医院 携带外源基因的复制型hbv载体、其转染后产生的重组hbv,和相应的制备方法与应用
GB201321384D0 (en) * 2013-12-04 2014-01-15 Isis Innovation Molecular adjuvant

Also Published As

Publication number Publication date
US20200113998A1 (en) 2020-04-16
SG11201909353VA (en) 2019-11-28
DK3609535T3 (da) 2025-08-18
US12521431B2 (en) 2026-01-13
AU2018251241B2 (en) 2025-04-17
JP2020516264A (ja) 2020-06-11
EP3609535A1 (en) 2020-02-19
KR102700586B1 (ko) 2024-08-30
AU2018251241A1 (en) 2019-10-31
ES3036962T3 (en) 2025-09-25
JP7326157B2 (ja) 2023-08-15
CN110913899A (zh) 2020-03-24
KR20200024130A (ko) 2020-03-06
PH12019502310A1 (en) 2020-09-21
EP3609535B1 (en) 2025-06-25
MY202396A (en) 2024-04-25
CN110913899B (zh) 2024-04-19
CN118576699A (zh) 2024-09-03
CA3059290A1 (en) 2018-10-18
GB201705765D0 (en) 2017-05-24
WO2018189522A1 (en) 2018-10-18
US20240115694A1 (en) 2024-04-11

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