MX2019009189A - Metodos de cultivo por perfusion con microportadores y usos de los mismos. - Google Patents
Metodos de cultivo por perfusion con microportadores y usos de los mismos.Info
- Publication number
- MX2019009189A MX2019009189A MX2019009189A MX2019009189A MX2019009189A MX 2019009189 A MX2019009189 A MX 2019009189A MX 2019009189 A MX2019009189 A MX 2019009189A MX 2019009189 A MX2019009189 A MX 2019009189A MX 2019009189 A MX2019009189 A MX 2019009189A
- Authority
- MX
- Mexico
- Prior art keywords
- culturing methods
- perfusion culturing
- microcarrier perfusion
- methods
- microcarrier
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
- C12N5/0075—General culture methods using substrates using microcarriers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2527/00—Culture process characterised by the use of mechanical forces, e.g. strain, vibration
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2531/00—Microcarriers
Abstract
Esta invención proporciona métodos de cultivo de una célula de mamífero y varios métodos que utilizan estos métodos de cultivo.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361768085P | 2013-02-22 | 2013-02-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019009189A true MX2019009189A (es) | 2019-09-26 |
Family
ID=50240051
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015010941A MX367025B (es) | 2013-02-22 | 2014-02-21 | Metodos de cultivo por perfusion con microportadores y usos de los mismos. |
MX2019009189A MX2019009189A (es) | 2013-02-22 | 2015-08-21 | Metodos de cultivo por perfusion con microportadores y usos de los mismos. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015010941A MX367025B (es) | 2013-02-22 | 2014-02-21 | Metodos de cultivo por perfusion con microportadores y usos de los mismos. |
Country Status (9)
Country | Link |
---|---|
US (3) | US9909101B2 (es) |
EP (1) | EP2958988A2 (es) |
CN (1) | CN105209603A (es) |
AU (1) | AU2014218723B2 (es) |
CA (1) | CA2901950A1 (es) |
HK (1) | HK1219751A1 (es) |
MX (2) | MX367025B (es) |
SG (2) | SG11201506343QA (es) |
WO (1) | WO2014130872A2 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2717927T3 (es) | 2013-02-22 | 2019-06-26 | Genzyme Corp | Procedimientos de cultivo por perfusión de microportadores y usos de los mismos |
US9909101B2 (en) | 2013-02-22 | 2018-03-06 | Genzyme Corporation | Methods of perfusion culturing using a shake flask and microcarriers |
AR095196A1 (es) * | 2013-03-15 | 2015-09-30 | Regeneron Pharma | Medio de cultivo celular libre de suero |
TW202204596A (zh) | 2014-06-06 | 2022-02-01 | 美商健臻公司 | 灌注培養方法及其用途 |
TW202246486A (zh) | 2014-06-09 | 2022-12-01 | 美商健臻公司 | 種子罐培養法(seed train processes)及其用途 |
JP6843750B2 (ja) | 2014-12-22 | 2021-03-17 | ジェンザイム・コーポレーション | 哺乳類細胞の培養方法 |
EP3475410A4 (en) | 2016-06-24 | 2020-02-12 | Lonza Ltd | VARIABLE DIAMETER BIOREACTORS |
US11391725B2 (en) * | 2018-03-16 | 2022-07-19 | Genzyme Corporation | Methods for improving cell viability in a production bioreactor |
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US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
RU2058992C1 (ru) | 1993-07-14 | 1996-04-27 | Антипин Георгий Васильевич | Способ получения кормового белка и устройство для его осуществления |
RU2215748C2 (ru) | 1999-04-09 | 2003-11-10 | Сентро Де Инмунология Молекулар | Способ получения рекомбинантного эритропоэтина человека и полученный эритропоэтин, фармацевтическая композиция |
US6585971B1 (en) * | 1999-11-12 | 2003-07-01 | Harbor-Ucla Research And Education Institute | Recombinant α-L-iduronidase, methods for producing and purifying the same and methods for treating disease caused by deficiencies thereof |
EP1395647B1 (en) | 2000-12-20 | 2006-11-22 | Bayer Pharmaceuticals Corporation | A device and method for seed-train expansion of mammalian cells |
CA2460206C (en) * | 2001-10-02 | 2012-01-24 | Novo Nordisk Health Care Ag | Method for production of recombinant proteins in eukaryote cells |
WO2003039459A2 (en) * | 2001-11-05 | 2003-05-15 | Genvec, Inc. | Viral vector production methods and compositions |
US6953692B2 (en) * | 2001-12-18 | 2005-10-11 | Bayer Pharmaceuticals Corporation | Device and method for seed-train expansion of mammalian cells |
US20050186669A1 (en) | 2004-02-20 | 2005-08-25 | Cesco Bioengineering Co., Ltd. | Apparatus and method for preparing and culturing cells |
CA2579680A1 (en) | 2004-09-16 | 2006-03-30 | Becton, Dickinson And Company | Perfusion bioreactor for culturing cells |
DK1807101T3 (en) | 2004-09-30 | 2016-05-23 | Bayer Healthcare Llc | Devices and methods for integrated continuous production of biological molecules |
WO2006138143A1 (en) | 2005-06-15 | 2006-12-28 | Amprotein Corporation | Suspension culture vessels |
ES2662589T3 (es) | 2005-06-15 | 2018-04-09 | Zhejiang Jinyishengshi Bioengineering Co., Ltd. | Recipientes para cultivo en suspensión |
WO2008024769A2 (en) * | 2006-08-21 | 2008-02-28 | Raven Biotechnologies, Inc. | Intensified perfusion production method |
WO2008073620A2 (en) | 2006-11-02 | 2008-06-19 | Neose Technologies, Inc. | Manufacturing process for the production of polypeptides expressed in insect cell-lines |
US8501462B2 (en) | 2007-02-27 | 2013-08-06 | The Board Of Trustees Of The University Of Illinois | Insert device for multiwell plate |
US9012212B2 (en) | 2007-04-17 | 2015-04-21 | Xendo Holding B.V. | Method and device for continuous membrane adsorption |
WO2009023562A2 (en) | 2007-08-09 | 2009-02-19 | Wyeth | Use of perfusion to enhance production of fed-batch cell culture in bioreactors |
WO2009034186A2 (en) | 2007-09-13 | 2009-03-19 | Helmholtz-Zentrum für Infektionsforschung GmbH | Process for cell cultivation |
US20090233334A1 (en) | 2008-03-11 | 2009-09-17 | Excellgene Sa | Cell cultivation and production of recombinant proteins by means of an orbital shake bioreactor system with disposable bags at the 1,500 liter scale |
DE102008019691A1 (de) | 2008-04-15 | 2009-10-29 | Technische Universität Ilmenau | Teilaktives mikrofluidisches System für die 3D-Zellkultivierung sowie Verfahren zu dessen Perfusion |
CN101821378B (zh) | 2008-06-16 | 2015-07-08 | 浙江金仪盛世生物工程有限公司 | 生物反应器 |
US8728479B2 (en) | 2009-03-31 | 2014-05-20 | The Trustees Of The University Of Pennsylvania | Antigen-binding proteins comprising recombinant protein scaffolds |
CN101875917B (zh) * | 2009-04-28 | 2012-07-04 | 北京清大天一科技有限公司 | 生物反应器微载体培养动物细胞生产猪瘟疫苗的方法 |
CN201933090U (zh) * | 2010-11-22 | 2011-08-17 | 朱学仁 | 细胞微载体灌注培养截留装置 |
US20130260419A1 (en) | 2010-12-06 | 2013-10-03 | Thomas C. Ransohoff | Continuous processing methods for biological products |
US9163089B2 (en) * | 2011-05-12 | 2015-10-20 | Probiogen Ag | Enhancement of protein production yield mediated by a fast shuttling CDC42 GTPase |
WO2013116449A1 (en) | 2012-02-02 | 2013-08-08 | Corning Incorporated | Automatic continuous perfusion cell culture microplate consumables |
SG10201607963SA (en) | 2012-04-01 | 2016-11-29 | Emd Millipore Corp | Cell culture and gradient migration assay method and devices |
US20140154726A1 (en) | 2012-10-23 | 2014-06-05 | Genzyme Corporation | Perfusion Culturing Methods and Uses Thereof |
US9909101B2 (en) | 2013-02-22 | 2018-03-06 | Genzyme Corporation | Methods of perfusion culturing using a shake flask and microcarriers |
ES2717927T3 (es) | 2013-02-22 | 2019-06-26 | Genzyme Corp | Procedimientos de cultivo por perfusión de microportadores y usos de los mismos |
WO2014137903A2 (en) | 2013-03-08 | 2014-09-12 | Genzyme Corporation | Integrated continuous manufacturing of therapeutic protein drug substances |
CA2906600A1 (en) | 2013-03-15 | 2014-09-18 | Genzyme Corporation | High-density cell banking methods |
WO2015039115A1 (en) | 2013-09-16 | 2015-03-19 | Genzyme Corporation | Methods and systems for processing a cell culture |
TWI671312B (zh) | 2014-01-17 | 2019-09-11 | 美商健臻公司 | 無菌層析法及製法 |
TWI709569B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析樹脂及其用於製造方法的用途 |
KR102391259B1 (ko) | 2014-06-04 | 2022-04-26 | 암젠 인크 | 포유류 세포 배양물을 회수하는 방법 |
TW202204596A (zh) | 2014-06-06 | 2022-02-01 | 美商健臻公司 | 灌注培養方法及其用途 |
TW202246486A (zh) | 2014-06-09 | 2022-12-01 | 美商健臻公司 | 種子罐培養法(seed train processes)及其用途 |
CN104450597B (zh) * | 2014-12-10 | 2020-07-28 | 青岛农业大学 | 一种石油降解菌固体菌剂的制备方法及由其制备的固体菌剂修复石油污染的土壤的方法 |
JP6843750B2 (ja) | 2014-12-22 | 2021-03-17 | ジェンザイム・コーポレーション | 哺乳類細胞の培養方法 |
-
2014
- 2014-02-21 US US14/769,772 patent/US9909101B2/en not_active Expired - Fee Related
- 2014-02-21 AU AU2014218723A patent/AU2014218723B2/en not_active Ceased
- 2014-02-21 SG SG11201506343QA patent/SG11201506343QA/en unknown
- 2014-02-21 CN CN201480022766.8A patent/CN105209603A/zh active Pending
- 2014-02-21 WO PCT/US2014/017803 patent/WO2014130872A2/en active Application Filing
- 2014-02-21 MX MX2015010941A patent/MX367025B/es active IP Right Grant
- 2014-02-21 EP EP14709106.0A patent/EP2958988A2/en not_active Withdrawn
- 2014-02-21 CA CA2901950A patent/CA2901950A1/en not_active Abandoned
- 2014-02-21 SG SG10201806083RA patent/SG10201806083RA/en unknown
-
2015
- 2015-08-21 MX MX2019009189A patent/MX2019009189A/es unknown
-
2016
- 2016-06-30 HK HK16107617.0A patent/HK1219751A1/zh unknown
-
2018
- 2018-01-18 US US15/874,645 patent/US10577583B2/en not_active Expired - Fee Related
-
2020
- 2020-03-02 US US16/807,057 patent/US20200255798A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US9909101B2 (en) | 2018-03-06 |
SG10201806083RA (en) | 2018-08-30 |
MX2015010941A (es) | 2016-06-07 |
SG11201506343QA (en) | 2015-09-29 |
US10577583B2 (en) | 2020-03-03 |
AU2014218723A1 (en) | 2015-09-10 |
MX367025B (es) | 2019-08-02 |
EP2958988A2 (en) | 2015-12-30 |
WO2014130872A2 (en) | 2014-08-28 |
CA2901950A1 (en) | 2014-08-28 |
US20160002594A1 (en) | 2016-01-07 |
HK1219751A1 (zh) | 2017-04-13 |
US20180148684A1 (en) | 2018-05-31 |
WO2014130872A3 (en) | 2014-10-16 |
US20200255798A1 (en) | 2020-08-13 |
CN105209603A (zh) | 2015-12-30 |
AU2014218723B2 (en) | 2019-12-05 |
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