MX2019004938A - Cápsula compleja que contiene esomeprazol y método de preparación de esta. - Google Patents
Cápsula compleja que contiene esomeprazol y método de preparación de esta.Info
- Publication number
- MX2019004938A MX2019004938A MX2019004938A MX2019004938A MX2019004938A MX 2019004938 A MX2019004938 A MX 2019004938A MX 2019004938 A MX2019004938 A MX 2019004938A MX 2019004938 A MX2019004938 A MX 2019004938A MX 2019004938 A MX2019004938 A MX 2019004938A
- Authority
- MX
- Mexico
- Prior art keywords
- coating layer
- layer formed
- core
- esomeprazole
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4833—Encapsulating processes; Filling of capsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se proporciona una cápsula compuesta y un método de preparación de esta, comprendiendo la cápsula compuesta: una primera parte que se disuelve que comprende un núcleo que comprende, como principio activo, esomeprazol o una sal farmacéuticamente aceptable de este, una capa de recubrimiento interno sobre el núcleo y una primera capa de recubrimiento entérico sobre la capa de recubrimiento interno; y una segunda parte que se disuelve que comprende un núcleo que comprende, como principio activo, esomeprazol o una sal farmacéuticamente aceptable de este, una capa de recubrimiento interno sobre el núcleo y una segunda capa de recubrimiento entérico sobre la capa de recubrimiento interno, donde la primera capa de recubrimiento entérico comprende, como material base de recubrimiento, copolímero de ácido metacrílico LD en una cantidad de aproximadamente un 5% (p/p) a aproximadamente un 50% (p/p) del núcleo sobre el cual se forma la capa de recubrimiento interno, y la segunda capa de recubrimiento entérico comprende, como material base de recubrimiento, una mezcla que contiene copolimero de ácido metacrílieo S y biopolímero de ácido metacrílico L en una relación de aproximadamente l.5:1 (p/p) a aproximadamente 3.5:1 (p/p) en una cantidad de aproximadamente un 15% (p/p) a aproximadamente un 40% (p/p) del núcleo sobre el cual la capa de recubrimiento interno.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020160142156A KR101877350B1 (ko) | 2016-10-28 | 2016-10-28 | 에스오메프라졸 함유 복합 캡슐제 및 그 제조방법 |
| PCT/KR2017/011571 WO2018080104A1 (ko) | 2016-10-28 | 2017-10-19 | 에스오메프라졸 함유 복합 캡슐제 및 그 제조방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019004938A true MX2019004938A (es) | 2019-10-09 |
Family
ID=62023771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019004938A MX2019004938A (es) | 2016-10-28 | 2017-10-19 | Cápsula compleja que contiene esomeprazol y método de preparación de esta. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US11052048B2 (es) |
| EP (1) | EP3513784A4 (es) |
| JP (1) | JP2019532960A (es) |
| KR (1) | KR101877350B1 (es) |
| CN (1) | CN109890372B (es) |
| AU (1) | AU2017349091A1 (es) |
| BR (1) | BR112019008402A2 (es) |
| EA (1) | EA201990704A1 (es) |
| MX (1) | MX2019004938A (es) |
| PH (1) | PH12019500919A1 (es) |
| WO (1) | WO2018080104A1 (es) |
| ZA (1) | ZA201902867B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2020001760A (es) * | 2017-09-28 | 2020-07-29 | Hanmi Pharm Ind Co Ltd | Composicion farmaceutica que incluye un comprimido esferoide de multiples unidades que contiene esomeprazol y una sal farmaceuticamente aceptable esferoide de este, y metodo para preparar la composicion farmaceutica. |
| WO2020204609A1 (ko) * | 2019-04-02 | 2020-10-08 | 한미약품 주식회사 | 에스오메프라졸 또는 이의 약학적으로 허용 가능한 염을 포함하고 이중방출 프로파일을 갖는 약학적 조성물 |
| KR102312604B1 (ko) * | 2020-02-04 | 2021-10-15 | 한국유나이티드제약 주식회사 | 장용성의 프로톤펌프억제제 및 서방성의 모사프리드 제제를 포함하는 경질캡슐 제제 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA41946C2 (uk) | 1994-07-08 | 2001-10-15 | Астра Актієболаг | Оральна фармацевтична складова одинична дозована форма у вигляді таблетки, спосіб її одержання, упаковка у вигляді блістера та спосіб інгібування секреції шлункової кислоти і/або лікування шлунково-кишкових запальних захворювань |
| MY148805A (en) * | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
| KR20060065632A (ko) * | 2003-07-17 | 2006-06-14 | 닥터 레디스 래보러토리즈, 인코포레이티드 | 팽창성 코팅을 갖는 약제학적 조성물 |
| WO2005051362A2 (en) * | 2003-11-28 | 2005-06-09 | Ranbaxy Laboratories Limited | Oral benzimidazole compositions comprising an active core, an optional separating layer and an enteric coating |
| AR052225A1 (es) | 2004-11-04 | 2007-03-07 | Astrazeneca Ab | Formulaciones de tabletas de liberacion modificada par inhibidores de la bomba de protones |
| EP2319504A1 (en) * | 2009-11-07 | 2011-05-11 | Laboratorios Del. Dr. Esteve, S.A. | Pharmaceutical solid dosage form |
| WO2012001705A2 (en) * | 2010-06-29 | 2012-01-05 | Cadila Healthcare Limited | Pharmaceutical compositions of (r)-lansoprazole |
| CN102100671B (zh) * | 2011-01-14 | 2013-04-24 | 寿光富康制药有限公司 | 一种埃索美拉唑镁肠溶微丸的制备方法 |
| CN102670521B (zh) * | 2012-05-18 | 2014-05-21 | 珠海润都制药股份有限公司 | 一种埃索美拉唑镁肠溶微丸及其制备方法 |
| CN102940611B (zh) * | 2012-11-26 | 2017-02-22 | 康普药业股份有限公司 | 一种含有埃索美拉唑镁的肠溶片剂 |
| CN103040774B (zh) * | 2012-11-30 | 2015-03-04 | 上海信谊万象药业股份有限公司 | 埃索美拉唑镁肠溶片中埃索美拉唑镁的制粒包衣工艺 |
| CN104940170A (zh) * | 2015-07-23 | 2015-09-30 | 浙江亚太药业股份有限公司 | 一种埃索美拉唑镁肠溶胶囊及其制备方法 |
-
2016
- 2016-10-28 KR KR1020160142156A patent/KR101877350B1/ko active IP Right Grant
-
2017
- 2017-10-19 BR BR112019008402A patent/BR112019008402A2/pt active Search and Examination
- 2017-10-19 JP JP2019519729A patent/JP2019532960A/ja not_active Ceased
- 2017-10-19 AU AU2017349091A patent/AU2017349091A1/en not_active Abandoned
- 2017-10-19 US US16/345,456 patent/US11052048B2/en active Active
- 2017-10-19 EA EA201990704A patent/EA201990704A1/ru unknown
- 2017-10-19 EP EP17866143.5A patent/EP3513784A4/en active Pending
- 2017-10-19 CN CN201780067122.4A patent/CN109890372B/zh active Active
- 2017-10-19 WO PCT/KR2017/011571 patent/WO2018080104A1/ko unknown
- 2017-10-19 MX MX2019004938A patent/MX2019004938A/es unknown
-
2019
- 2019-04-24 PH PH12019500919A patent/PH12019500919A1/en unknown
- 2019-05-07 ZA ZA2019/02867A patent/ZA201902867B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US11052048B2 (en) | 2021-07-06 |
| JP2019532960A (ja) | 2019-11-14 |
| PH12019500919A1 (en) | 2019-08-19 |
| AU2017349091A1 (en) | 2019-05-16 |
| KR20180046682A (ko) | 2018-05-09 |
| BR112019008402A2 (pt) | 2019-07-09 |
| CN109890372B (zh) | 2022-06-24 |
| EP3513784A1 (en) | 2019-07-24 |
| ZA201902867B (en) | 2020-08-26 |
| CN109890372A (zh) | 2019-06-14 |
| US20190247316A1 (en) | 2019-08-15 |
| EP3513784A4 (en) | 2020-06-03 |
| EA201990704A1 (ru) | 2019-09-30 |
| WO2018080104A1 (ko) | 2018-05-03 |
| KR101877350B1 (ko) | 2018-08-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12019500919A1 (en) | Esomeprazole~containing complex capsule and preparation method therefor | |
| MX2022002952A (es) | Formulaciones de liberacion modificada de 2-[3-[4-amino-3-(2-fluor o-4-fenoxi-fenil)pirazolo[3,4-d]pirimidin-1-il]piperidina-1-carbo nil]-4-metil-4-[4-(oxetan-3-il)piperazin-1-il]pent-2-enenitrilo. | |
| UA92030C2 (ru) | Фармацевтические композиции регулированного высвобождения нестабильных в кислой среде лекарственных средств | |
| WO2019108021A3 (ko) | 토파시티닙을 포함하는 약제학적 조성물 | |
| PH12017502376B1 (en) | Oral solid formulation containing irinotecan and method of preparing the same | |
| MX2021001905A (es) | Preparacion farmaceutica que tiene excelentes propiedades de disolucion, que contiene esomeprazol y bicarbonato de sodio. | |
| MX2013009253A (es) | Formulaciones multiparticuladas de l-mentol y metodos relacionados. | |
| PH12019500154A1 (en) | Formulation having improved ph-dependent drug-release characteristics, containing esomeprazole or pharmaceutically acceptable salt thereof | |
| PH12015502721B1 (en) | Pharmaceutical capsule composite formulation comprising tadalafil and tamsulosin | |
| EP3216450A8 (en) | Pharmaceutical preparation comprising cyclin inhibitor and preparation method thereof | |
| MX2021012441A (es) | Tableta enterica que contiene fumarato de dimetilo. | |
| PH12014502407A1 (en) | New alfentanil composition for the treatment of acute pain | |
| MX2021000769A (es) | Composicion farmaceutica que contiene clomipramina y metodo de preparacion de la misma. | |
| MX2017006168A (es) | Composiciones. | |
| CO2018002046A2 (es) | Nueva composición oral de libreación retardada dual de dexlansoprazol | |
| PH12017500536A1 (en) | Solid pharmaceutical composition comprising amlodipine and losartan | |
| EA201691763A1 (ru) | Стабильная быстрорастворимая лекарственная форма, содержащая амоксициллин и клавулановую кислоту | |
| PH12020550597A1 (en) | Formulation having improved hygroscopic property and dissolution rate comprising telmisartan or its pharmaceutically acceptable salt | |
| PL429672A1 (pl) | Preparat zawierający ksantohumol i zastosowanie ksantohumolu | |
| PH12018550075A1 (en) | An oral osmotic pharmaceutical composition of vildagliptin | |
| WO2018093096A3 (en) | Pharmaceutical complex preparation comprising amlodipine, losartan and rosuvastatin | |
| MX2018002449A (es) | Formulaciones de liberacion retardada, metodos de fabricacion y uso de las mismas. | |
| EA201500527A1 (ru) | Таблетки кветиапина с пролонгированным высвобождением и способ их получения | |
| WO2011154830A3 (es) | Forma farmaceutica de inhibidores de la fosfodiesterasa para administracion transmucosa |