MX2019004342A - Derivado de oxazina para usar en el tratamiento o la prevencion de la angiopatia amiloide cerebral. - Google Patents
Derivado de oxazina para usar en el tratamiento o la prevencion de la angiopatia amiloide cerebral.Info
- Publication number
- MX2019004342A MX2019004342A MX2019004342A MX2019004342A MX2019004342A MX 2019004342 A MX2019004342 A MX 2019004342A MX 2019004342 A MX2019004342 A MX 2019004342A MX 2019004342 A MX2019004342 A MX 2019004342A MX 2019004342 A MX2019004342 A MX 2019004342A
- Authority
- MX
- Mexico
- Prior art keywords
- prevention
- treatment
- amyloid angiopathy
- oxazine derivative
- cerebral amyloid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
La presente invención se refiere a un inhibidor de BACE-1 derivado de oxazina y composiciones farmacéuticas que comprenden dicho derivado de oxazina para usar en el tratamiento o la prevención de la angiopatía amiloide cerebral y, en particular, en donde el paciente tiene una o dos copias del alelo ApoE4.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16193770 | 2016-10-13 | ||
PCT/IB2017/056281 WO2018069843A1 (en) | 2016-10-13 | 2017-10-11 | An oxazine derivative for use in the treatment or prevention of cerebral amyloid angiopathy |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019004342A true MX2019004342A (es) | 2019-07-01 |
Family
ID=57133087
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019004342A MX2019004342A (es) | 2016-10-13 | 2017-10-11 | Derivado de oxazina para usar en el tratamiento o la prevencion de la angiopatia amiloide cerebral. |
Country Status (18)
Country | Link |
---|---|
US (1) | US10722518B2 (es) |
EP (1) | EP3525793A1 (es) |
JP (1) | JP2019534885A (es) |
KR (1) | KR20190068567A (es) |
CN (1) | CN109789145A (es) |
AU (1) | AU2017342207B2 (es) |
BR (1) | BR112019006591A2 (es) |
CA (1) | CA3035852A1 (es) |
CL (1) | CL2019001007A1 (es) |
IL (1) | IL265579A (es) |
JO (1) | JOP20190081A1 (es) |
MA (1) | MA46519A (es) |
MX (1) | MX2019004342A (es) |
PH (1) | PH12019500464A1 (es) |
RU (1) | RU2019113756A (es) |
SG (1) | SG11201901889QA (es) |
TW (1) | TW201817424A (es) |
WO (1) | WO2018069843A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017070184A1 (en) * | 2015-10-20 | 2017-04-27 | Washington University In St. Louis | Mri method for in vivo detection of amyloid and pathology in the alzheimer brain |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050215884A1 (en) | 2004-02-27 | 2005-09-29 | Greicius Michael D | Evaluation of Alzheimer's disease using an independent component analysis of an individual's resting-state functional MRI |
US9492114B2 (en) | 2004-06-18 | 2016-11-15 | Banner Health Systems, Inc. | Accelerated evaluation of treatments to prevent clinical onset of alzheimer's disease |
EA024059B1 (ru) * | 2011-01-13 | 2016-08-31 | Новартис Аг | Гетероциклические производные и их применение в лечении неврологических расстройств |
JO3458B1 (ar) | 2014-11-10 | 2020-07-05 | H Lundbeck As | 2- أمينو-6- (دايفلوروميثيل) – 5، 5- ديفلورو-6-فينيل-3،4، 5، 6-تيتراهيدروبيريدين كمثبطات bace1 |
JOP20190003A1 (ar) | 2016-07-19 | 2019-01-10 | Novartis Ag | مشتق أوكسازين للاستخدام في الوقاية من مرض ألزهايمر في مرضى عُرضه للخطر |
-
2017
- 2017-06-16 JO JOP/2019/0081A patent/JOP20190081A1/ar unknown
- 2017-10-11 KR KR1020197012852A patent/KR20190068567A/ko not_active Application Discontinuation
- 2017-10-11 RU RU2019113756A patent/RU2019113756A/ru not_active Application Discontinuation
- 2017-10-11 JP JP2019519407A patent/JP2019534885A/ja active Pending
- 2017-10-11 CN CN201780060026.7A patent/CN109789145A/zh active Pending
- 2017-10-11 MX MX2019004342A patent/MX2019004342A/es unknown
- 2017-10-11 MA MA046519A patent/MA46519A/fr unknown
- 2017-10-11 AU AU2017342207A patent/AU2017342207B2/en not_active Ceased
- 2017-10-11 EP EP17787965.7A patent/EP3525793A1/en not_active Withdrawn
- 2017-10-11 CA CA3035852A patent/CA3035852A1/en not_active Abandoned
- 2017-10-11 SG SG11201901889QA patent/SG11201901889QA/en unknown
- 2017-10-11 BR BR112019006591A patent/BR112019006591A2/pt not_active IP Right Cessation
- 2017-10-11 TW TW106134647A patent/TW201817424A/zh unknown
- 2017-10-11 US US15/730,175 patent/US10722518B2/en active Active
- 2017-10-11 WO PCT/IB2017/056281 patent/WO2018069843A1/en unknown
-
2019
- 2019-03-01 PH PH12019500464A patent/PH12019500464A1/en unknown
- 2019-03-24 IL IL265579A patent/IL265579A/en unknown
- 2019-04-12 CL CL2019001007A patent/CL2019001007A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
RU2019113756A (ru) | 2020-11-13 |
AU2017342207A1 (en) | 2019-03-21 |
CL2019001007A1 (es) | 2019-06-21 |
TW201817424A (zh) | 2018-05-16 |
BR112019006591A2 (pt) | 2019-07-02 |
US20180125853A1 (en) | 2018-05-10 |
CA3035852A1 (en) | 2018-04-19 |
AU2017342207B2 (en) | 2020-01-30 |
IL265579A (en) | 2019-05-30 |
WO2018069843A1 (en) | 2018-04-19 |
US10722518B2 (en) | 2020-07-28 |
RU2019113756A3 (es) | 2021-03-05 |
PH12019500464A1 (en) | 2019-11-25 |
MA46519A (fr) | 2019-08-21 |
WO2018069843A9 (en) | 2018-08-02 |
SG11201901889QA (en) | 2019-04-29 |
KR20190068567A (ko) | 2019-06-18 |
JOP20190081A1 (ar) | 2019-04-11 |
CN109789145A (zh) | 2019-05-21 |
EP3525793A1 (en) | 2019-08-21 |
JP2019534885A (ja) | 2019-12-05 |
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