MX2019000749A - Formas cristalinas de 4-ciano-n-(2-(4,4-dimetilciclohex-1-en-1-il) -6-(2,2,6,6-tetrametiltetrahidro-2h-piran-4-il)piridin-3-il)-1h-i midazol-2-carboxamida. - Google Patents
Formas cristalinas de 4-ciano-n-(2-(4,4-dimetilciclohex-1-en-1-il) -6-(2,2,6,6-tetrametiltetrahidro-2h-piran-4-il)piridin-3-il)-1h-i midazol-2-carboxamida.Info
- Publication number
- MX2019000749A MX2019000749A MX2019000749A MX2019000749A MX2019000749A MX 2019000749 A MX2019000749 A MX 2019000749A MX 2019000749 A MX2019000749 A MX 2019000749A MX 2019000749 A MX2019000749 A MX 2019000749A MX 2019000749 A MX2019000749 A MX 2019000749A
- Authority
- MX
- Mexico
- Prior art keywords
- dimethylcyclohex
- pyran
- imidazole
- cyano
- crystalline forms
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Liquid Crystal Substances (AREA)
- Pyrane Compounds (AREA)
Abstract
La presente descripcion describe formas cristalinas de 4-ciano-N-[2-(4,4-dimetilciclohex-1-en-1-il)-6- 2,2,6,6-tetrametiltetrahidro-2H-piran-4-il)piridina-3-il]-1H-imid azol-2-carboxamida.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662363622P | 2016-07-18 | 2016-07-18 | |
PCT/US2017/042310 WO2018017444A1 (en) | 2016-07-18 | 2017-07-17 | Crystalline forms of 4-cyano-n-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2h-pyran-4-yl)pyridin-3-yl)-1h-imidazole-2-carboxamide |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019000749A true MX2019000749A (es) | 2019-08-29 |
Family
ID=59631847
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019000749A MX2019000749A (es) | 2016-07-18 | 2017-07-17 | Formas cristalinas de 4-ciano-n-(2-(4,4-dimetilciclohex-1-en-1-il) -6-(2,2,6,6-tetrametiltetrahidro-2h-piran-4-il)piridin-3-il)-1h-i midazol-2-carboxamida. |
MX2021006739A MX2021006739A (es) | 2016-07-18 | 2019-01-17 | Formas cristalinas de 4-ciano-n-(2-(4,4-dimetilciclohex-1-en-1-il) -6-(2,2,6,6-tetrametiltetrahidro-2h-piran-4-il)piridin-3-il)-1h-i midazol-2-carboxamida. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021006739A MX2021006739A (es) | 2016-07-18 | 2019-01-17 | Formas cristalinas de 4-ciano-n-(2-(4,4-dimetilciclohex-1-en-1-il) -6-(2,2,6,6-tetrametiltetrahidro-2h-piran-4-il)piridin-3-il)-1h-i midazol-2-carboxamida. |
Country Status (16)
Country | Link |
---|---|
US (1) | US10314821B2 (es) |
EP (1) | EP3484872B1 (es) |
JP (1) | JP2019521159A (es) |
KR (1) | KR20190026910A (es) |
CN (1) | CN109952296A (es) |
AR (1) | AR109079A1 (es) |
AU (1) | AU2017299506B2 (es) |
BR (1) | BR112019000982A2 (es) |
CA (1) | CA3031230A1 (es) |
EA (1) | EA201990320A1 (es) |
ES (1) | ES2935647T3 (es) |
MA (1) | MA45685A (es) |
MX (2) | MX2019000749A (es) |
TW (1) | TWI752980B (es) |
UY (1) | UY37338A (es) |
WO (1) | WO2018017444A1 (es) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JO3240B1 (ar) * | 2007-10-17 | 2018-03-08 | Janssen Pharmaceutica Nv | c-fms مثبطات كيناز |
JP2011502266A (ja) * | 2007-10-31 | 2011-01-20 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Fms治療に対する応答を評価するバイオマーカー |
JOP20180012A1 (ar) | 2012-08-07 | 2019-01-30 | Janssen Pharmaceutica Nv | عملية السلفنة باستخدام نونافلوروبوتانيسولفونيل فلوريد |
RS57103B1 (sr) * | 2013-03-15 | 2018-06-29 | Janssen Pharmaceutica Nv | Supstituisani derivati piridina korisni kao inhibitori c-fms kinaze |
US20160015700A1 (en) | 2013-03-15 | 2016-01-21 | Carla DE BOER | 4-cyano-n-(2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyltetrahydro-2h-pyran-4-yl)pyridin-3-yl)-1h-imidazole-2-carboxamide for the treatment of hodgkin's lymphoma |
-
2017
- 2017-07-14 TW TW106123583A patent/TWI752980B/zh active
- 2017-07-17 WO PCT/US2017/042310 patent/WO2018017444A1/en unknown
- 2017-07-17 EP EP17752511.0A patent/EP3484872B1/en active Active
- 2017-07-17 BR BR112019000982-5A patent/BR112019000982A2/pt active Search and Examination
- 2017-07-17 ES ES17752511T patent/ES2935647T3/es active Active
- 2017-07-17 CA CA3031230A patent/CA3031230A1/en active Pending
- 2017-07-17 MA MA045685A patent/MA45685A/fr unknown
- 2017-07-17 AU AU2017299506A patent/AU2017299506B2/en active Active
- 2017-07-17 KR KR1020197004327A patent/KR20190026910A/ko not_active Application Discontinuation
- 2017-07-17 CN CN201780057364.5A patent/CN109952296A/zh active Pending
- 2017-07-17 US US15/651,385 patent/US10314821B2/en active Active
- 2017-07-17 AR ARP170101991A patent/AR109079A1/es unknown
- 2017-07-17 EA EA201990320A patent/EA201990320A1/ru unknown
- 2017-07-17 MX MX2019000749A patent/MX2019000749A/es unknown
- 2017-07-17 JP JP2019502219A patent/JP2019521159A/ja active Pending
- 2017-07-19 UY UY0001037338A patent/UY37338A/es unknown
-
2019
- 2019-01-17 MX MX2021006739A patent/MX2021006739A/es unknown
Also Published As
Publication number | Publication date |
---|---|
JP2019521159A (ja) | 2019-07-25 |
CA3031230A1 (en) | 2018-01-25 |
KR20190026910A (ko) | 2019-03-13 |
AU2017299506A1 (en) | 2019-02-07 |
EP3484872A1 (en) | 2019-05-22 |
TW201808941A (zh) | 2018-03-16 |
UY37338A (es) | 2018-01-31 |
EA201990320A1 (ru) | 2019-06-28 |
EP3484872B1 (en) | 2022-11-30 |
AU2017299506B2 (en) | 2021-08-05 |
US20180133197A1 (en) | 2018-05-17 |
WO2018017444A1 (en) | 2018-01-25 |
TWI752980B (zh) | 2022-01-21 |
MA45685A (fr) | 2019-05-22 |
AR109079A1 (es) | 2018-10-24 |
US10314821B2 (en) | 2019-06-11 |
ES2935647T3 (es) | 2023-03-08 |
BR112019000982A2 (pt) | 2019-05-14 |
MX2021006739A (es) | 2021-07-15 |
CN109952296A (zh) | 2019-06-28 |
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