MX2019000546A - Preparacion farmaceutica para la administración oral con uniformidad del contenido mejorada, que comprende perlas de liberación sostenida que continenen hidrocloruro de tamsulosina. - Google Patents
Preparacion farmaceutica para la administración oral con uniformidad del contenido mejorada, que comprende perlas de liberación sostenida que continenen hidrocloruro de tamsulosina.Info
- Publication number
- MX2019000546A MX2019000546A MX2019000546A MX2019000546A MX2019000546A MX 2019000546 A MX2019000546 A MX 2019000546A MX 2019000546 A MX2019000546 A MX 2019000546A MX 2019000546 A MX2019000546 A MX 2019000546A MX 2019000546 A MX2019000546 A MX 2019000546A
- Authority
- MX
- Mexico
- Prior art keywords
- tamsulosin hydrochloride
- extended release
- pharmaceutical preparation
- oral pharmaceutical
- release pellet
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se proporciona una formulación farmacéutica oral que incluye perlas de liberación sostenida que contienen hidrocloruro de tamsulosina y un aditivo farmacéuticamente aceptable, en donde las perlas de liberación sostenida incluyen aproximadamente 50% en peso a aproximadamente 100% en peso de partículas que tienen un tamaño de partícula de aproximadamente 0.50 mm a aproximadamente 0.85 mm y menos de aproximadamente 15% en peso de partículas que tienen un tamaño de partícula menor que aproximadamente 0.50 mm. La formulación farmacéutica oral puede tener una desviación reducida en la tasa de disolución de hidrocloruro de tamsulosina y una uniformidad de contenido mejorada entre las formas de dosificación unitaria y tiene una calidad garantizada debido a la alta reproducibilidad de las formas de dosificación unitaria.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20160090266 | 2016-07-15 | ||
PCT/KR2017/007586 WO2018012931A1 (ko) | 2016-07-15 | 2017-07-14 | 함량 균일성이 개선된 탐수로신 염산염 함유 서방성 펠렛을 포함하는 경구용 약제학적 제제 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2019000546A true MX2019000546A (es) | 2019-10-04 |
Family
ID=60952686
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019000546A MX2019000546A (es) | 2016-07-15 | 2017-07-14 | Preparacion farmaceutica para la administración oral con uniformidad del contenido mejorada, que comprende perlas de liberación sostenida que continenen hidrocloruro de tamsulosina. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20210322319A1 (es) |
EP (1) | EP3485877A4 (es) |
JP (1) | JP2019524683A (es) |
KR (1) | KR102419638B1 (es) |
CN (1) | CN109475503B (es) |
AU (1) | AU2017297117A1 (es) |
BR (1) | BR112019000721A2 (es) |
EA (1) | EA201892778A1 (es) |
MX (1) | MX2019000546A (es) |
PH (1) | PH12019500059A1 (es) |
WO (1) | WO2018012931A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20200078146A (ko) | 2018-12-21 | 2020-07-01 | 한미약품 주식회사 | 내산성이 우수한 탐수로신 염산염 함유 제약 조성물 및 이의 제조방법 |
CN110420179A (zh) * | 2019-08-12 | 2019-11-08 | 韩育娟 | 一种炎琥宁干混悬剂及其制备方法 |
CN114504560A (zh) * | 2022-03-10 | 2022-05-17 | 河南省人民医院 | 一种盐酸坦索罗辛缓释制剂及其制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050106253A1 (en) * | 2003-11-13 | 2005-05-19 | Platteeuw Johannes J. | Pharmaceutical pellets comprising tamsulosin |
KR100570419B1 (ko) * | 2004-01-14 | 2006-04-11 | 코오롱제약주식회사 | 염산 탐술로신의 경구 투여용 서방성 펠렛 조성물 및 그제조방법 |
KR100582350B1 (ko) * | 2004-02-17 | 2006-05-22 | 한미약품 주식회사 | 탐수로신 염산염의 경구투여용 조성물 및 이의 서방성과립 제제 |
KR100678421B1 (ko) * | 2005-02-11 | 2007-02-02 | 주식회사 씨티씨바이오 | 염산 탐스로신 함유 방출조절 제제 |
KR20070044911A (ko) * | 2005-10-26 | 2007-05-02 | 주식회사 씨티씨바이오 | 염산 탐스로신 함유 방출조절 제제 |
KR100912680B1 (ko) * | 2006-03-16 | 2009-08-19 | (주) 벡스코아 | 제어 방출 제형 |
KR100745515B1 (ko) * | 2006-04-10 | 2007-08-02 | 주식회사 대웅제약 | 염산 탐술로신 함유 서방성 펠렛 및 그의 제조방법 |
CN101125134B (zh) * | 2006-08-16 | 2010-09-15 | 常州市第四制药厂有限公司 | 盐酸坦洛新缓释胶囊及其制备方法 |
CN101695478B (zh) * | 2009-10-23 | 2012-01-18 | 江苏大学 | 盐酸坦索罗辛缓释微丸制剂及其制备方法 |
KR101686033B1 (ko) * | 2010-04-12 | 2016-12-13 | 주식회사 대웅제약 | 탐술로신 또는 이의 약제학적 허용 가능한 염을 유효성분으로 함유하는 장용성 서방형 펠렛부와 속방부로 이루어진 의약 조성물 |
KR20160100570A (ko) * | 2015-02-16 | 2016-08-24 | 한미약품 주식회사 | 탐수로신 염산염 함유 서방성 과립을 포함하는 경구용 약제학적 제제 |
-
2017
- 2017-07-14 JP JP2018568830A patent/JP2019524683A/ja not_active Ceased
- 2017-07-14 WO PCT/KR2017/007586 patent/WO2018012931A1/ko unknown
- 2017-07-14 EP EP17828001.2A patent/EP3485877A4/en active Pending
- 2017-07-14 AU AU2017297117A patent/AU2017297117A1/en not_active Abandoned
- 2017-07-14 US US16/318,034 patent/US20210322319A1/en not_active Abandoned
- 2017-07-14 CN CN201780043959.5A patent/CN109475503B/zh active Active
- 2017-07-14 BR BR112019000721-0A patent/BR112019000721A2/pt active Search and Examination
- 2017-07-14 EA EA201892778A patent/EA201892778A1/ru unknown
- 2017-07-14 KR KR1020170089677A patent/KR102419638B1/ko active IP Right Grant
- 2017-07-14 MX MX2019000546A patent/MX2019000546A/es unknown
-
2019
- 2019-01-09 PH PH12019500059A patent/PH12019500059A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2018012931A1 (ko) | 2018-01-18 |
EP3485877A1 (en) | 2019-05-22 |
KR102419638B1 (ko) | 2022-07-12 |
JP2019524683A (ja) | 2019-09-05 |
BR112019000721A2 (pt) | 2019-05-07 |
US20210322319A1 (en) | 2021-10-21 |
EA201892778A1 (ru) | 2019-06-28 |
EP3485877A4 (en) | 2020-02-26 |
PH12019500059A1 (en) | 2019-10-14 |
CN109475503B (zh) | 2021-09-17 |
AU2017297117A1 (en) | 2019-01-24 |
KR20180008339A (ko) | 2018-01-24 |
CN109475503A (zh) | 2019-03-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2013130669A8 (en) | Pharmaceutical composition and administration thereof | |
PH12017502326A1 (en) | Orodispersible dosage unit containing an estetrol component | |
MX2019000546A (es) | Preparacion farmaceutica para la administración oral con uniformidad del contenido mejorada, que comprende perlas de liberación sostenida que continenen hidrocloruro de tamsulosina. | |
PH12017502325A1 (en) | Orodispersible dosage unit containing an estetrol component | |
MX2020007554A (es) | Formulacion farmaceutica que comprende esomeprazol y bicarbonato de sodio. | |
PH12017501986A1 (en) | Pharmaceutical complex formulation comprising amlodipine, losartan and rosuvastatin | |
MX2020007552A (es) | Composicion farmaceutica estable que comprende esomeprazol y bicarbonato de sodio. | |
PH12020500525A1 (en) | Manufacturing of pharmaceutical compositions | |
MX2013007587A (es) | Suplementos alimenticios en particulas medicados para animales y metodos de preparacion. | |
MX2016017131A (es) | Composicion novedosa de un producto de confiteria. | |
MX2019010228A (es) | Composición para liberación controlada de sustancias fisiológicamente activas y proceso para su preparación. | |
MY144613A (en) | Formulations of suberoylanilide hydroxamic acid and methods for producing same | |
MX2017015322A (es) | Composicion farmaceutica oral de isotretinoin. | |
IN2013MU01177A (es) | ||
MX2015011624A (es) | Composiciones farmaceuticas secas que comprenden nanoparticulas de agente activo ligadas a particulas portadoras. | |
WO2017121637A8 (en) | Process for the preparation of pellets | |
EA033291B1 (ru) | Единица дозирования, содержащая рамиприл и бисопролола гемифумарат, способ ее получения и способ лечения гипертензии | |
MX2022013576A (es) | Composicion para la liberacion controlada de sustancias fisiologicamente activas y proceso para su preparacion. | |
PH12019550098A1 (en) | Nutritional composition in powder form provided in single serving capsules | |
MX2017015699A (es) | Composiciones de acido diclofenaco. | |
EP3877379A4 (en) | CRYSTALLINE FORM OF NILOTINIB HYDROCHLORIDE, METHOD FOR PREPARING IT AND PHARMACEUTICAL COMPOSITION CONTAINING IT | |
PH12018502103A1 (en) | Particle size and distribution of polymer for melt extrusion application | |
WO2016008401A8 (zh) | 一种含多西他赛的药物组合物 | |
BR112017021111A2 (pt) | processo para fabricação de misturas de pós secos | |
CN105461078A (zh) | 一种水质改良剂 |