MX2018008206A - Tiolasas modificadas que pueden producir compuestos ramificados y usos de las mismas. - Google Patents

Tiolasas modificadas que pueden producir compuestos ramificados y usos de las mismas.

Info

Publication number
MX2018008206A
MX2018008206A MX2018008206A MX2018008206A MX2018008206A MX 2018008206 A MX2018008206 A MX 2018008206A MX 2018008206 A MX2018008206 A MX 2018008206A MX 2018008206 A MX2018008206 A MX 2018008206A MX 2018008206 A MX2018008206 A MX 2018008206A
Authority
MX
Mexico
Prior art keywords
modified
branched compounds
producing branched
thiolases
thiolases capable
Prior art date
Application number
MX2018008206A
Other languages
English (en)
Inventor
Bernal Sánchez Vicente
TORRES SALAS Pamela
Morreale De León Antonio
BARRERA BURGOS Víctor
Del Mar Gonzalez Barroso María
LÓPEZ GALLEGO Fernando
GAGO BADENAS Federico
Alejandro Sánchez Murcia Pedro
Original Assignee
Repsol Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Repsol Sa filed Critical Repsol Sa
Publication of MX2018008206A publication Critical patent/MX2018008206A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00Preparation of sulfur-containing organic compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La invención se refiere a tiolasas mutantes que pueden producir compuestos ramificados que se considera que son de particular interés en la industria. La invención también se refiere a un método para obtener dicho producto ramificado.
MX2018008206A 2015-12-29 2016-12-29 Tiolasas modificadas que pueden producir compuestos ramificados y usos de las mismas. MX2018008206A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15382676 2015-12-29
PCT/EP2016/082840 WO2017114897A1 (en) 2015-12-29 2016-12-29 Modified thiolases capable of producing branched compounds and uses thereof

Publications (1)

Publication Number Publication Date
MX2018008206A true MX2018008206A (es) 2019-07-08

Family

ID=55274954

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018008206A MX2018008206A (es) 2015-12-29 2016-12-29 Tiolasas modificadas que pueden producir compuestos ramificados y usos de las mismas.

Country Status (6)

Country Link
US (1) US20200270653A1 (es)
EP (1) EP3397758B1 (es)
CN (1) CN108699537A (es)
ES (1) ES2846907T3 (es)
MX (1) MX2018008206A (es)
WO (1) WO2017114897A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180187169A1 (en) * 2016-08-16 2018-07-05 Massachusetts Institute Of Technology Thiolase variants and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008124523A1 (en) * 2007-04-04 2008-10-16 The Regents Of The University Of California Butanol production by recombinant microorganisms
JP2010004763A (ja) * 2008-06-25 2010-01-14 Kaneka Corp β−ケトチオラーゼ変異体
WO2010022763A1 (en) * 2008-08-25 2010-03-04 Metabolic Explorer Method for the preparation of 2-hydroxy-isobutyrate
DE112010004469T5 (de) * 2009-11-17 2012-09-06 Basf Plant Science Company Gmbh Pflanzen mit erhöhtem Ertrag
WO2014006203A1 (en) * 2012-07-06 2014-01-09 Clariant Produkte (Deutschland) Gmbh Engineered clostridium strain for butanol production
WO2015108605A2 (en) * 2013-11-01 2015-07-23 Massachusetts Institute Of Technology Microbial production of branched medium chain alcohols, such as 4- methylpentanol

Also Published As

Publication number Publication date
WO2017114897A1 (en) 2017-07-06
US20200270653A1 (en) 2020-08-27
CN108699537A (zh) 2018-10-23
ES2846907T3 (es) 2021-07-30
EP3397758A1 (en) 2018-11-07
EP3397758B1 (en) 2020-11-25

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