MX2018007636A - Inhibidores de tirosinasa. - Google Patents

Inhibidores de tirosinasa.

Info

Publication number
MX2018007636A
MX2018007636A MX2018007636A MX2018007636A MX2018007636A MX 2018007636 A MX2018007636 A MX 2018007636A MX 2018007636 A MX2018007636 A MX 2018007636A MX 2018007636 A MX2018007636 A MX 2018007636A MX 2018007636 A MX2018007636 A MX 2018007636A
Authority
MX
Mexico
Prior art keywords
aryl
integer
alkyl
peptide group
iib
Prior art date
Application number
MX2018007636A
Other languages
English (en)
Inventor
Chandramowli Ganesh
RAMANATHAN Gurunath
Thimmaiah Sreenivasa
Garima Tripathi
Original Assignee
Unilever Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Nv filed Critical Unilever Nv
Publication of MX2018007636A publication Critical patent/MX2018007636A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3481—Organic compounds containing oxygen
    • A23L3/349—Organic compounds containing oxygen with singly-bound oxygen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3481—Organic compounds containing oxygen
    • A23L3/3508—Organic compounds containing oxygen containing carboxyl groups
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3481—Organic compounds containing oxygen
    • A23L3/3508—Organic compounds containing oxygen containing carboxyl groups
    • A23L3/3517—Carboxylic acid esters
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describe un compuesto de las fórmulas (I), (IIA) o (lIB) para usarse para tratar hiperpigmentación de piel humana al inhibir la actividad de tirosinasa humana en un substrato animado, el cual es piel humana que contiene tirosinasa humana. (I) (IIA) (lIB) donde: X es oxígeno, azufre, selenio o telurio; R es grupo -OH, alquilo, arilo o péptido; R1 es grupo -OH, alquilo, arilo o péptido; R2 es grupo -OH, alquilo, arilo o péptido; n es un entero de 2 a 5; m es un entero de 2 a 4 y p es un entero de 2 a 4. (ver Fórmulas).
MX2018007636A 2015-12-24 2016-11-23 Inhibidores de tirosinasa. MX2018007636A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15202739 2015-12-24
PCT/EP2016/078566 WO2017108316A1 (en) 2015-12-24 2016-11-23 Tyrosinase inhibitors

Publications (1)

Publication Number Publication Date
MX2018007636A true MX2018007636A (es) 2018-09-21

Family

ID=55066405

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018007636A MX2018007636A (es) 2015-12-24 2016-11-23 Inhibidores de tirosinasa.

Country Status (5)

Country Link
US (1) US10729628B2 (es)
EP (1) EP3393604A1 (es)
CN (1) CN108472516B (es)
MX (1) MX2018007636A (es)
WO (1) WO2017108316A1 (es)

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60241873A (ja) 1984-05-14 1985-11-30 Purimahamu Kk 肉加工品の製造方法
US5965524A (en) * 1989-07-07 1999-10-12 Peptide Technologies Corporation Analogs of viscosin and uses thereof
JPH05170637A (ja) 1991-12-25 1993-07-09 Narisu Keshohin:Kk 美白化粧料
JPH05170636A (ja) 1991-12-25 1993-07-09 Narisu Keshohin:Kk 美白化粧料
WO2002008174A1 (en) * 2000-07-26 2002-01-31 Patrick Anthony Riley Phenylethylamine derivatives and their use in the treatment of melanoma
JP2002284668A (ja) 2001-03-26 2002-10-03 Cosmo Products Kk クスミの予防・治療剤
AU2003298647A1 (en) 2002-11-14 2004-06-15 Claussen, Randal, C. Synthesis and self-assembly of abc triblock bola peptide
DE10306452A1 (de) 2003-02-17 2004-09-02 Beiersdorf Ag Neue Aminosäurederivate
FR2870244B1 (fr) 2004-05-11 2011-01-07 Centre Nat Rech Scient Conjugues dipeptidiques antagonistes de l'alpha-msh
TWI409169B (zh) 2005-02-21 2013-09-21 Dainippon Printing Co Ltd Anti-glare optical laminate
PL1878784T3 (pl) 2005-04-20 2013-07-31 Jx Nippon Oil & Energy Corp Kompozycja oleju silnikowego o dużej żywotności oszczędzająca zużycie paliwa
DE102006011883A1 (de) 2006-03-09 2007-09-13 Beiersdorf Ag Tropolon- und Hydroxybenzol-substituierte Oligopeptide zur Depigmentierung
JP5582516B2 (ja) 2007-08-10 2014-09-03 独立行政法人産業技術総合研究所 繊維芽細胞増殖因子制御ペプチド
FR2921828B1 (fr) 2007-10-04 2012-06-29 Oreal Composition cosmetique ou pharmaceutique comprenant un polycondensat, ledit polycondensat et procede de traitement cosmetique.
KR101222685B1 (ko) 2009-02-12 2013-01-16 주식회사 웰스킨 다이펩타이드를 포함하는 피부 미백용 화장품 조성물
TWI387578B (zh) * 2009-09-11 2013-03-01 Corum Inc 具有羧酸基與醯胺基之化合物及其應用
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WO2011126163A1 (ko) 2010-04-08 2011-10-13 주식회사 웰스킨 다이펩타이드를 포함하는 피부 미백용 조성물
FR2958641B1 (fr) 2010-04-08 2014-12-26 Sederma Sa Nouveaux composes de type polyterpenique, compositions cosmetiques, nutraceutiques et pharmaceutiques les contenant et utilisations dans ces domaines.
EP2593462B1 (en) * 2010-07-14 2016-09-07 Betta Pharmaceuticals Co., Ltd. Novel fused heterocyclic derivatives useful as c-met tyrosine kinase inhibitors
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WO2012121428A1 (ko) 2011-03-07 2012-09-13 주식회사 웰스킨 다이펩타이드를 유효성분으로 포함하는 섬유모세포 증식 조성물 및 상기 조성물을 포함하는 제품
MX358016B (es) 2011-10-28 2018-08-02 Neostrata Company Inc Star Derivados de n-acildipeptido y sus usos.
KR101167285B1 (ko) 2011-11-18 2012-07-23 에이앤펩주식회사 피부 미백 활성을 갖는 나이아신-펩타이드 및 그의 용도
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JP6326601B2 (ja) 2013-03-13 2018-05-23 アンティース ソシエテ アノニム 皮膚更新のためのペプチド及び前記ペプチドを使用する方法
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Also Published As

Publication number Publication date
US10729628B2 (en) 2020-08-04
EP3393604A1 (en) 2018-10-31
CN108472516B (zh) 2021-10-26
WO2017108316A1 (en) 2017-06-29
CN108472516A (zh) 2018-08-31
US20190008737A1 (en) 2019-01-10

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