MX2018002816A - Metodos de tratamiento de mieloma multiple y leucemia de celulas plasmaticas mediante terapia de celulas t. - Google Patents
Metodos de tratamiento de mieloma multiple y leucemia de celulas plasmaticas mediante terapia de celulas t.Info
- Publication number
- MX2018002816A MX2018002816A MX2018002816A MX2018002816A MX2018002816A MX 2018002816 A MX2018002816 A MX 2018002816A MX 2018002816 A MX2018002816 A MX 2018002816A MX 2018002816 A MX2018002816 A MX 2018002816A MX 2018002816 A MX2018002816 A MX 2018002816A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- multiple myeloma
- treating multiple
- cell leukemia
- plasma cell
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 208000034578 Multiple myelomas Diseases 0.000 title abstract 2
- 206010035226 Plasma cell myeloma Diseases 0.000 title abstract 2
- 208000031223 plasma cell leukemia Diseases 0.000 title abstract 2
- 238000002659 cell therapy Methods 0.000 title 1
- 230000000735 allogeneic effect Effects 0.000 abstract 4
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464452—Transcription factors, e.g. SOX or c-MYC
- A61K39/464453—Wilms tumor 1 [WT1]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
Abstract
Se describen en la presente métodos para tratar mieloma múltiple en un paciente humano que lo necesite, que comprenden administrar al paciente humano una población de células alogénicas que comprende células T alogénicas específicas de WT1. También se describen en la presente métodos para tratar leucemia de células plasmáticas en un paciente humano que lo necesite, que comprenden administrar al paciente humano una población de células alogénicas que comprende células T alogénicas específicas de WT1.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562216525P | 2015-09-10 | 2015-09-10 | |
US201562220641P | 2015-09-18 | 2015-09-18 | |
PCT/US2016/050857 WO2017044678A1 (en) | 2015-09-10 | 2016-09-09 | Methods of treating multiple myeloma and plasma cell leukemia by t cell therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018002816A true MX2018002816A (es) | 2018-06-08 |
Family
ID=57068181
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018002816A MX2018002816A (es) | 2015-09-10 | 2016-09-09 | Metodos de tratamiento de mieloma multiple y leucemia de celulas plasmaticas mediante terapia de celulas t. |
Country Status (14)
Country | Link |
---|---|
US (1) | US20190381098A1 (es) |
EP (1) | EP3347028A1 (es) |
JP (1) | JP6947720B2 (es) |
KR (1) | KR20180048992A (es) |
CN (1) | CN108348552A (es) |
AU (1) | AU2016320877A1 (es) |
CA (1) | CA2997757A1 (es) |
HK (1) | HK1257882A1 (es) |
IL (1) | IL257929B1 (es) |
MX (1) | MX2018002816A (es) |
RU (1) | RU2743381C2 (es) |
TW (1) | TWI759270B (es) |
WO (1) | WO2017044678A1 (es) |
ZA (1) | ZA201801656B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2017415310B2 (en) | 2017-05-25 | 2023-08-03 | Memorial Sloan Kettering Cancer Center | Use of the IL-15/IL-15Rα complex in the generation of antigen-specific T cells for adoptive immunotherapy |
CA3074516A1 (en) | 2017-10-23 | 2019-05-02 | Atara Biotherapeutics, Inc. | Methods of managing tumor flare in adoptive immunotherapy |
US20210000874A1 (en) | 2018-03-14 | 2021-01-07 | Memorial Sloan Kettering Cancer Center | Methods of selecting t cell line for adoptive cellular therapy |
CN111643525A (zh) * | 2020-06-16 | 2020-09-11 | 济宁医学院 | 引发免疫排斥反应在肿瘤治疗中的应用及其方法 |
CN113881632B (zh) * | 2021-09-29 | 2023-09-29 | 四川省医学科学院·四川省人民医院 | 一种提高dc细胞活性的细胞培养基及培养方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1178956C (zh) * | 1998-07-31 | 2004-12-08 | 杉山治夫 | 基于癌抑制基因wt1的产物的癌抗原 |
CA2349442C (en) * | 1998-09-30 | 2012-12-04 | Corixa Corporation | Compositions and methods for wt1 specific immunotherapy |
ES2378264T3 (es) * | 2003-11-05 | 2012-04-10 | International Institute Of Cancer Immunology, Inc. | Péptido antigénico de unión a HLA-DR derivado de WT1 |
FR2931163B1 (fr) * | 2008-05-16 | 2013-01-18 | Ets Francais Du Sang | Lignee de cellules dendritiques plasmacytoides utilisee en therapie cellulaire active ou adoptive |
RU2506311C2 (ru) * | 2008-10-30 | 2014-02-10 | Йеда Рисёрч Энд Девелопмент Ко. Лтд. | Т-клетки центральной памяти против третьей стороны, способы их получения и их применение в трансплантации и лечении заболеваний |
WO2013106834A2 (en) * | 2012-01-13 | 2013-07-18 | Memorial Sloan Kettering Cancer Center | Immunogenic wt-1 peptides and methods of use thereof |
-
2016
- 2016-09-09 KR KR1020187009368A patent/KR20180048992A/ko active Search and Examination
- 2016-09-09 TW TW105129257A patent/TWI759270B/zh not_active IP Right Cessation
- 2016-09-09 CN CN201680064239.2A patent/CN108348552A/zh active Pending
- 2016-09-09 US US15/758,566 patent/US20190381098A1/en not_active Abandoned
- 2016-09-09 WO PCT/US2016/050857 patent/WO2017044678A1/en active Application Filing
- 2016-09-09 MX MX2018002816A patent/MX2018002816A/es unknown
- 2016-09-09 EP EP16775897.8A patent/EP3347028A1/en not_active Withdrawn
- 2016-09-09 CA CA2997757A patent/CA2997757A1/en active Pending
- 2016-09-09 IL IL257929A patent/IL257929B1/en unknown
- 2016-09-09 AU AU2016320877A patent/AU2016320877A1/en not_active Abandoned
- 2016-09-09 JP JP2018512945A patent/JP6947720B2/ja active Active
- 2016-09-09 RU RU2018112526A patent/RU2743381C2/ru active
-
2018
- 2018-03-09 ZA ZA2018/01656A patent/ZA201801656B/en unknown
-
2019
- 2019-01-08 HK HK19100243.4A patent/HK1257882A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
JP2018530534A (ja) | 2018-10-18 |
CA2997757A1 (en) | 2017-03-16 |
ZA201801656B (en) | 2022-12-21 |
RU2743381C2 (ru) | 2021-02-17 |
WO2017044678A1 (en) | 2017-03-16 |
CN108348552A (zh) | 2018-07-31 |
RU2018112526A (ru) | 2019-10-10 |
RU2018112526A3 (es) | 2020-01-31 |
HK1257882A1 (zh) | 2019-11-01 |
TW201714619A (zh) | 2017-05-01 |
US20190381098A1 (en) | 2019-12-19 |
AU2016320877A1 (en) | 2018-04-19 |
IL257929A (en) | 2018-05-31 |
IL257929B1 (en) | 2024-02-01 |
JP6947720B2 (ja) | 2021-10-13 |
EP3347028A1 (en) | 2018-07-18 |
KR20180048992A (ko) | 2018-05-10 |
TWI759270B (zh) | 2022-04-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PH12017502154A1 (en) | Methods for conditioning patients for t cell therapy | |
NZ765695A (en) | Immune cell organoid co-cultures | |
PH12017500787A1 (en) | Methods of selecting t cell line and donor thereof for adoptive cellular therapy | |
MX2019014009A (es) | Metodos mejorados para la elaboracion de terapias celulares adoptivas. | |
MX2021001878A (es) | Metodos y composiciones para mejorar las celulas t reguladoras cd4+. | |
CA2956871C (en) | Compounds active towards bromodomains | |
MX2019003616A (es) | Celulas beta derivadas de celulas madre (sc-beta) y composiciones y metodos para generarlas. | |
MX2018002816A (es) | Metodos de tratamiento de mieloma multiple y leucemia de celulas plasmaticas mediante terapia de celulas t. | |
NZ631701A (en) | Apoptosis-including agents for the treatment of cancer and immune and autoimmune diseases | |
MX2015009106A (es) | Composiciones de solución sólida y su uso en el tratamiento del dolor intenso. | |
MX2020010194A (es) | Agente reductor de amoniaco para usarse en el tratamiento de enfermedades asociadas con activacion de celulas estrelladas hepaticas. | |
NZ742327A (en) | Neural cell extracellular vessicles | |
PH12017501993A1 (en) | Methods of treating epstein-barr-virus-associated lymphoproliferative disorders by t cell therapy | |
MX365392B (es) | Composición de combinación de pac-1 y doxorrubicina. | |
EP4275746A3 (en) | Extracellular vesicles derived from osteoblastic lineage cells for therapeutic and diagnostic use | |
PH12016500863A1 (en) | Tetracyclic autotaxin inhibitors | |
MX365403B (es) | Peptidos y metodos para usarlos. | |
MX2017012867A (es) | Composiciones terapeuticas y metodos de uso para tratar el cancer. | |
EP3998341A3 (en) | Adenoviral vectors | |
MX2019013862A (es) | Terapia de combinacion. | |
MX2019000677A (es) | Células miméticas de células b. | |
MX2017013666A (es) | Terapia de combinacion de agente anti-fuctactico y agente de inmunoterapia y composiciones para el tratamiento de cancer. | |
AU2018288712A1 (en) | Methods for treating merkel cell carcinoma (MCC) using NK-92 cells | |
AR105142A1 (es) | Métodos de tratamiento del glioblastoma multiforme con terapia de células t | |
AU2018250008B2 (en) | Macro-encapsulated therapeutic cells and methods of using the same |