MX2018001926A - Composiciones que comprenden inhibidores de fosfoinositida 3-quinasa y un segundo agente antiproliferativo. - Google Patents

Composiciones que comprenden inhibidores de fosfoinositida 3-quinasa y un segundo agente antiproliferativo.

Info

Publication number
MX2018001926A
MX2018001926A MX2018001926A MX2018001926A MX2018001926A MX 2018001926 A MX2018001926 A MX 2018001926A MX 2018001926 A MX2018001926 A MX 2018001926A MX 2018001926 A MX2018001926 A MX 2018001926A MX 2018001926 A MX2018001926 A MX 2018001926A
Authority
MX
Mexico
Prior art keywords
inhibitors
phosphoinositide
compositions
kinase inhibitors
antiproliferative agent
Prior art date
Application number
MX2018001926A
Other languages
English (en)
Spanish (es)
Inventor
Joseph Shuttleworth Stephen
David WHALE Andrew
Original Assignee
Karus Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karus Therapeutics Ltd filed Critical Karus Therapeutics Ltd
Publication of MX2018001926A publication Critical patent/MX2018001926A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53861,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/69Boron compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2018001926A 2015-08-19 2016-08-19 Composiciones que comprenden inhibidores de fosfoinositida 3-quinasa y un segundo agente antiproliferativo. MX2018001926A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1514760.6A GB201514760D0 (en) 2015-08-19 2015-08-19 Compounds and method of use
PCT/GB2016/052575 WO2017029517A1 (en) 2015-08-19 2016-08-19 Compositions comprising phosphoinositide 3-kinase inhibitors and a second antiproliferative agent

Publications (1)

Publication Number Publication Date
MX2018001926A true MX2018001926A (es) 2018-06-19

Family

ID=54258859

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018001926A MX2018001926A (es) 2015-08-19 2016-08-19 Composiciones que comprenden inhibidores de fosfoinositida 3-quinasa y un segundo agente antiproliferativo.

Country Status (22)

Country Link
US (3) US10668077B2 (https=)
EP (1) EP3337477B1 (https=)
JP (1) JP2018523689A (https=)
KR (1) KR20180064387A (https=)
CN (2) CN113786409B (https=)
AU (1) AU2016307885B2 (https=)
CA (1) CA2995898A1 (https=)
DK (1) DK3337477T3 (https=)
ES (1) ES2939815T3 (https=)
FI (1) FI3337477T3 (https=)
GB (1) GB201514760D0 (https=)
HR (1) HRP20230376T1 (https=)
HU (1) HUE061615T2 (https=)
IL (1) IL257499A (https=)
LT (1) LT3337477T (https=)
MX (1) MX2018001926A (https=)
PL (1) PL3337477T3 (https=)
PT (1) PT3337477T (https=)
RS (1) RS64095B1 (https=)
SI (1) SI3337477T1 (https=)
SM (1) SMT202300063T1 (https=)
WO (1) WO2017029517A1 (https=)

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GB201514751D0 (en) 2015-08-19 2015-09-30 Karus Therapeutics Ltd Compounds
GB201514758D0 (en) 2015-08-19 2015-09-30 Karus Therapeutics Ltd Formulation
GB201514754D0 (en) 2015-08-19 2015-09-30 Karus Therapeutics Ltd Compounds
SG11202102343QA (en) * 2018-09-11 2021-04-29 Curis Inc Combination therapy with a phosphoinositide 3-kinase inhibitor with a zinc binding moiety
JPWO2020059705A1 (ja) * 2018-09-18 2021-08-30 株式会社ヤクルト本社 キノリンカルボキサミド誘導体を用いるがん併用療法
PT3930715T (pt) * 2019-02-27 2024-08-02 Astrazeneca Ab Saracatinib para uso no tratamento de fibrose pulmonar idiopática
CN111904958B (zh) * 2019-05-09 2022-09-13 浙江大学 Umi-77作为线粒体自噬诱导剂在制备治疗炎症及神经退行性疾病药物中的应用
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WO2022105836A1 (en) * 2020-11-19 2022-05-27 Guangzhou Healthquest Pharma Co., Ltd. Combination therapies for treating cancer

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Also Published As

Publication number Publication date
DK3337477T3 (en) 2023-02-20
HK1251467A1 (en) 2019-02-01
US20230066999A1 (en) 2023-03-02
SMT202300063T1 (it) 2023-03-17
IL257499A (en) 2018-07-31
CN108348505B (zh) 2021-10-12
US12257254B2 (en) 2025-03-25
KR20180064387A (ko) 2018-06-14
HRP20230376T1 (hr) 2023-06-23
AU2016307885B2 (en) 2019-07-25
EP3337477B1 (en) 2023-02-01
US20210069200A1 (en) 2021-03-11
PT3337477T (pt) 2023-03-20
US10668077B2 (en) 2020-06-02
CN113786409B (zh) 2024-04-02
US11291669B2 (en) 2022-04-05
HUE061615T2 (hu) 2023-07-28
JP2018523689A (ja) 2018-08-23
WO2017029517A1 (en) 2017-02-23
GB201514760D0 (en) 2015-09-30
CN113786409A (zh) 2021-12-14
CA2995898A1 (en) 2017-02-23
US20180243313A1 (en) 2018-08-30
FI3337477T3 (fi) 2023-04-27
CN108348505A (zh) 2018-07-31
SI3337477T1 (sl) 2023-04-28
PL3337477T3 (pl) 2023-07-03
RS64095B1 (sr) 2023-04-28
LT3337477T (lt) 2023-03-10
AU2016307885A1 (en) 2018-03-08
EP3337477A1 (en) 2018-06-27
ES2939815T3 (es) 2023-04-27

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