MX2017016109A - Microorganismo recombinante para la produccion mejorada de productos quimicos finos. - Google Patents

Microorganismo recombinante para la produccion mejorada de productos quimicos finos.

Info

Publication number
MX2017016109A
MX2017016109A MX2017016109A MX2017016109A MX2017016109A MX 2017016109 A MX2017016109 A MX 2017016109A MX 2017016109 A MX2017016109 A MX 2017016109A MX 2017016109 A MX2017016109 A MX 2017016109A MX 2017016109 A MX2017016109 A MX 2017016109A
Authority
MX
Mexico
Prior art keywords
alanine
recombinant microorganism
improved production
recombinant
nucleic acid
Prior art date
Application number
MX2017016109A
Other languages
English (en)
Inventor
Wang Qingzhao
Siraj Ratani Shakir
David BLANKSCHIEN Matthew
Kumar Mukesh
JAITZIG Jennifer
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of MX2017016109A publication Critical patent/MX2017016109A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01011—Aspartate-semialdehyde dehydrogenase (1.2.1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/01—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with NAD+ or NADP+ as acceptor (1.4.1)
    • C12Y104/01004—Glutamate dehydrogenase (NADP+) (1.4.1.4)

Abstract

La presente invención se refiere a una molécula de ácido nucleico recombinante, un microorganismo recombinante, un método para producir alanina y uso de la molécula de ácido nucleico recombinante o del microorganismo recombinante para la producción fermentativa de alanina.
MX2017016109A 2015-06-12 2016-06-09 Microorganismo recombinante para la produccion mejorada de productos quimicos finos. MX2017016109A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562174529P 2015-06-12 2015-06-12
US201562180081P 2015-06-16 2015-06-16
PCT/EP2016/063172 WO2016198529A1 (en) 2015-06-12 2016-06-09 Recombinant microorganism for improved production of alanine

Publications (1)

Publication Number Publication Date
MX2017016109A true MX2017016109A (es) 2018-04-20

Family

ID=56194443

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017016109A MX2017016109A (es) 2015-06-12 2016-06-09 Microorganismo recombinante para la produccion mejorada de productos quimicos finos.

Country Status (11)

Country Link
US (2) US10837034B2 (es)
EP (1) EP3307902A1 (es)
JP (1) JP2018516587A (es)
KR (1) KR20180011324A (es)
CN (1) CN107690478B (es)
CA (1) CA2988810A1 (es)
MX (1) MX2017016109A (es)
MY (1) MY189932A (es)
PH (1) PH12017502240A1 (es)
RU (1) RU2018100807A (es)
WO (1) WO2016198529A1 (es)

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* Cited by examiner, † Cited by third party
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US11952581B2 (en) 2003-08-01 2024-04-09 Basf Plant Science Gmbh Process for the production of polyunsaturated fatty acids in transgenic organisms
EP2166070B1 (de) 2003-08-01 2015-09-16 BASF Plant Science GmbH Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in transgenen Organismen
AR059376A1 (es) 2006-02-21 2008-03-26 Basf Plant Science Gmbh Procedimiento para la produccion de acidos grasos poliinsaturados
CA2988415A1 (en) * 2015-06-04 2016-12-08 Basf Se Recombinant microorganism for improved production of fine chemicals
CN108707617A (zh) * 2018-05-28 2018-10-26 河北大学 一种l-丙氨酸脱氢酶人工合成基因的获得方法及其应用
CN108660142A (zh) * 2018-05-28 2018-10-16 河北大学 一种高产l-丙氨酸的基因及其工程菌的构建方法
CN108660103A (zh) * 2018-05-29 2018-10-16 河北大学 一种高产l-丙氨酸的基因工程菌及其构建方法
CN113462623B (zh) * 2021-05-25 2022-11-29 天津科技大学 微生物发酵法制备d-丙氨酸的方法

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US5019509A (en) 1988-04-20 1991-05-28 Genetics Institute, Inc. Method and compositions for the production of l-alanine and derivatives thereof
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ES2149962T3 (es) 1993-12-09 2000-11-16 Univ Jefferson Compuestos y metodos para mutaciones dirigidas al sitio en celulas eucarioticas.
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RU2268305C2 (ru) 2003-12-18 2006-01-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) Способ получения l-аминокислот с использованием бактерий с оптимизированным уровнем генной экспрессии
DE102004003411A1 (de) 2004-01-23 2005-09-01 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
WO2007120198A2 (en) 2005-11-08 2007-10-25 University Of Florida Research Foundation, Inc. Materials and methods for improved microbial production of organic compounds
EP2186881B1 (en) 2006-03-23 2014-04-23 Ajinomoto Co., Inc. A method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA
JP2010110217A (ja) 2007-02-22 2010-05-20 Ajinomoto Co Inc Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法
WO2008119009A2 (en) 2007-03-27 2008-10-02 University Of Florida Research Foundation, Inc. Materials and methods for efficient alanine production
WO2008141226A2 (en) * 2007-05-10 2008-11-20 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacteria comprising vectors for expression of nucleic acid sequences encoding antigens
RU2392322C2 (ru) * 2007-08-14 2010-06-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) СПОСОБ ПОЛУЧЕНИЯ L-ТРЕОНИНА С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ, ПРИНАДЛЕЖАЩЕЙ К РОДУ Escherichia, В КОТОРОЙ ИНАКТИВИРОВАН ГЕН yahN
RU2007147436A (ru) 2007-12-21 2009-06-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Бактерия-продуцент (2s,3r,4s)-4-гидрокси-l-изолейцина и способ продукции (2s,3r,4s)-4-гидрокси-l-изолейцина
EP4321615A3 (en) * 2009-04-30 2024-02-21 Genomatica, Inc. Organisms for the production of 1,3-butanediol
WO2012150155A1 (de) 2011-05-03 2012-11-08 Basf Se Verfahren zur herstellung eines kristallinen l-mgda-trialkalimetallsalzes
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CA2920814A1 (en) 2013-08-30 2015-03-05 Basf Se Modified microorganism for improved production of alanine
MY181068A (en) 2013-09-25 2020-12-17 Basf Se Recombinant microorganism for improved production of fine chemicals
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Also Published As

Publication number Publication date
RU2018100807A (ru) 2019-07-12
JP2018516587A (ja) 2018-06-28
CN107690478B (zh) 2023-02-03
EP3307902A1 (en) 2018-04-18
CA2988810A1 (en) 2016-12-15
US10837034B2 (en) 2020-11-17
PH12017502240A1 (en) 2018-06-11
US20210032667A1 (en) 2021-02-04
CN107690478A (zh) 2018-02-13
KR20180011324A (ko) 2018-01-31
US20200032304A1 (en) 2020-01-30
MY189932A (en) 2022-03-22
RU2018100807A3 (es) 2019-07-17
WO2016198529A1 (en) 2016-12-15

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