MX2017010555A - Composicion liquida topica que comprende melatonina. - Google Patents
Composicion liquida topica que comprende melatonina.Info
- Publication number
- MX2017010555A MX2017010555A MX2017010555A MX2017010555A MX2017010555A MX 2017010555 A MX2017010555 A MX 2017010555A MX 2017010555 A MX2017010555 A MX 2017010555A MX 2017010555 A MX2017010555 A MX 2017010555A MX 2017010555 A MX2017010555 A MX 2017010555A
- Authority
- MX
- Mexico
- Prior art keywords
- melatonin
- liquid composition
- topical liquid
- ivf
- inhibition
- Prior art date
Links
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 title abstract 4
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 title abstract 4
- 229960003987 melatonin Drugs 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000007788 liquid Substances 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 238000003744 In vitro fertilisation Methods 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 1
- 238000002513 implantation Methods 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a una nueva formulación a base de melatonina, en particular una composición líquida tópica de melatonina (o un análogo de la misma) adecuada para uso en el lavado intrauterino realizado durante la reproducción asistida médicamente (por ejemplo, la fertilización in vitro - IVF); la melatonina es notoriamente inestable, especialmente en solución; las composiciones de la invención exhiben una alta estabilidad, lo que les permite mantenerse durante períodos prolongados antes de su uso eventual para la inhibición o la prevención del fallo en la implantación embrionaria.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15155389 | 2015-02-17 | ||
PCT/EP2016/053197 WO2016131784A1 (en) | 2015-02-17 | 2016-02-15 | Topical liquid composition comprising melatonin |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017010555A true MX2017010555A (es) | 2017-12-07 |
Family
ID=52595073
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017010555A MX2017010555A (es) | 2015-02-17 | 2016-02-15 | Composicion liquida topica que comprende melatonina. |
Country Status (16)
Country | Link |
---|---|
US (1) | US10188631B2 (es) |
EP (1) | EP3258910A1 (es) |
JP (1) | JP6889117B2 (es) |
KR (1) | KR20170116152A (es) |
CN (1) | CN107249572A (es) |
AR (1) | AR103719A1 (es) |
AU (2) | AU2016221796A1 (es) |
BR (1) | BR112017017432A2 (es) |
CA (1) | CA2975331A1 (es) |
HK (1) | HK1243649A1 (es) |
IL (1) | IL253934A0 (es) |
MX (1) | MX2017010555A (es) |
RU (1) | RU2017132292A (es) |
SG (1) | SG11201706363QA (es) |
WO (1) | WO2016131784A1 (es) |
ZA (1) | ZA201705632B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019038586A1 (en) | 2017-08-19 | 2019-02-28 | Ftf Pharma Private Limited | PHARMACEUTICAL COMPOSITION OF MELATONIN |
WO2019147026A1 (ko) * | 2018-01-23 | 2019-08-01 | 차의과학대학교 산학협력단 | 멜라토닌을 포함하는, 배아 발달용 조성물 및 이를 이용하여 배아 발달의 효율을 향상시키는 방법 |
CN116267895A (zh) * | 2022-08-03 | 2023-06-23 | 北京市农林科学院 | 褪黑素核受体RORα在提高冷冻精液品质中的用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1312377B1 (it) * | 1999-03-05 | 2002-04-15 | Uni Ci S R L | Composizioni a base di acido tiottico, cisteina e/o n-acetil cisteinada utilizzarsi in preparazioni farmaceutiche, dietetiche e cosmetiche |
US8415094B2 (en) * | 2007-12-21 | 2013-04-09 | Jaffar Ali bin M. Abdullah | Protein-free gamete and embryo handling and culture media products |
ITMI20120913A1 (it) | 2012-05-28 | 2013-11-29 | Nicoletta Maxia | Uso della n-acetil-5-metossitriptamina o suoi analoghi per favorire il meccanismo di impianto dell' embrione, e relative composizioni e mezzi di coltura |
-
2016
- 2016-02-15 KR KR1020177025750A patent/KR20170116152A/ko not_active Application Discontinuation
- 2016-02-15 SG SG11201706363QA patent/SG11201706363QA/en unknown
- 2016-02-15 AU AU2016221796A patent/AU2016221796A1/en not_active Abandoned
- 2016-02-15 BR BR112017017432-4A patent/BR112017017432A2/pt not_active IP Right Cessation
- 2016-02-15 US US15/548,315 patent/US10188631B2/en not_active Expired - Fee Related
- 2016-02-15 MX MX2017010555A patent/MX2017010555A/es unknown
- 2016-02-15 RU RU2017132292A patent/RU2017132292A/ru unknown
- 2016-02-15 WO PCT/EP2016/053197 patent/WO2016131784A1/en active Application Filing
- 2016-02-15 CA CA2975331A patent/CA2975331A1/en not_active Abandoned
- 2016-02-15 CN CN201680010542.4A patent/CN107249572A/zh active Pending
- 2016-02-15 EP EP16704628.3A patent/EP3258910A1/en not_active Withdrawn
- 2016-02-15 JP JP2017561037A patent/JP6889117B2/ja active Active
- 2016-02-17 AR ARP160100421A patent/AR103719A1/es unknown
-
2017
- 2017-08-09 IL IL253934A patent/IL253934A0/en unknown
- 2017-08-18 ZA ZA2017/05632A patent/ZA201705632B/en unknown
-
2018
- 2018-03-08 HK HK18103278.7A patent/HK1243649A1/zh unknown
-
2021
- 2021-03-24 AU AU2021201851A patent/AU2021201851A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP6889117B2 (ja) | 2021-06-18 |
HK1243649A1 (zh) | 2018-07-20 |
BR112017017432A2 (pt) | 2018-04-03 |
US10188631B2 (en) | 2019-01-29 |
WO2016131784A1 (en) | 2016-08-25 |
IL253934A0 (en) | 2017-10-31 |
RU2017132292A (ru) | 2019-03-18 |
JP2018510210A (ja) | 2018-04-12 |
AR103719A1 (es) | 2017-05-31 |
CA2975331A1 (en) | 2016-08-25 |
AU2021201851A1 (en) | 2021-04-22 |
US20180021308A1 (en) | 2018-01-25 |
EP3258910A1 (en) | 2017-12-27 |
KR20170116152A (ko) | 2017-10-18 |
AU2016221796A1 (en) | 2017-08-17 |
SG11201706363QA (en) | 2017-09-28 |
CN107249572A (zh) | 2017-10-13 |
ZA201705632B (en) | 2018-12-19 |
RU2017132292A3 (es) | 2019-08-21 |
NZ734192A (en) | 2020-11-27 |
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