MX2017002856A - Anticuerpos siglec de reaccion cruzada. - Google Patents
Anticuerpos siglec de reaccion cruzada.Info
- Publication number
- MX2017002856A MX2017002856A MX2017002856A MX2017002856A MX2017002856A MX 2017002856 A MX2017002856 A MX 2017002856A MX 2017002856 A MX2017002856 A MX 2017002856A MX 2017002856 A MX2017002856 A MX 2017002856A MX 2017002856 A MX2017002856 A MX 2017002856A
- Authority
- MX
- Mexico
- Prior art keywords
- cross reactive
- siglec antibodies
- reactive siglec
- agents
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Esta invención se refiere a agentes que enlazan múltiples Siglecs, incluyendo anticuerpos que neutralizan la actividad inhibidora de múltiples Siglec-7 y Siglec-9 en linfocitos. Tales agentes pueden usarse para el tratamiento de cánceres o enfermedades infecciosas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462048292P | 2014-09-10 | 2014-09-10 | |
PCT/EP2015/070550 WO2016038064A1 (en) | 2014-09-10 | 2015-09-09 | Cross reactive siglec antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017002856A true MX2017002856A (es) | 2017-05-30 |
Family
ID=54072835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017002856A MX2017002856A (es) | 2014-09-10 | 2015-09-09 | Anticuerpos siglec de reaccion cruzada. |
Country Status (8)
Country | Link |
---|---|
US (1) | US20170306014A1 (es) |
EP (1) | EP3191517B1 (es) |
JP (2) | JP2017532025A (es) |
AU (1) | AU2015314316B2 (es) |
CA (1) | CA2957351A1 (es) |
DK (1) | DK3191517T3 (es) |
MX (1) | MX2017002856A (es) |
WO (1) | WO2016038064A1 (es) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016038064A1 (en) | 2014-09-10 | 2016-03-17 | Innate Pharma | Cross reactive siglec antibodies |
EP3325967B1 (en) | 2015-07-24 | 2019-12-04 | Innate Pharma | Methods for detecting tissue infiltrating nk cells |
CN115960235A (zh) | 2015-08-28 | 2023-04-14 | 艾利妥 | 抗siglec-7抗体及其使用方法 |
CA3003458A1 (en) * | 2015-10-29 | 2017-05-04 | Alector Llc | Anti-siglec-9 antibodies and methods of use thereof |
AU2016354924A1 (en) | 2015-11-17 | 2018-06-21 | Innate Pharma | Siglec-10 antibodies |
AU2017207807A1 (en) * | 2016-01-12 | 2018-07-12 | Palleon Pharmaceuticals Inc. | Use of Siglec-7 or Siglec-9 antibodies for the treatment of cancer |
US11078274B2 (en) * | 2016-03-08 | 2021-08-03 | Innate Pharma | Siglec neutralizing antibodies |
US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
GB201611535D0 (en) * | 2016-07-01 | 2016-08-17 | King's College London | Methods and compositions for treating cancer with siglec-9 activity modulators |
WO2018006034A1 (en) | 2016-07-01 | 2018-01-04 | The Board Of Trustees Of The Leland Stanford Junior University | Conjugates for targeted cell surface editing |
CA3026588A1 (en) * | 2016-07-01 | 2018-01-04 | The Board Of Trustees Of The Leland Stanford Junior University | Inhibitory immune receptor inhibition methods and compositions |
JP7137563B2 (ja) * | 2016-08-05 | 2022-09-14 | アラコス,インコーポレイティド | がん治療用の抗Siglec-7抗体 |
CN106831989A (zh) * | 2017-01-04 | 2017-06-13 | 中国人民解放军南京军区军事医学研究所 | 人源抗唾液酸结合免疫球蛋白样凝集素‑7的抗体IgG及其应用 |
AU2018265856B2 (en) | 2017-05-12 | 2023-04-27 | Harpoon Therapeutics, Inc. | Mesothelin binding proteins |
WO2019011855A1 (en) * | 2017-07-10 | 2019-01-17 | Innate Pharma | ANTIBODIES NEUTRALIZING SIGLEC-9 |
EP3652207A1 (en) * | 2017-07-10 | 2020-05-20 | Innate Pharma | Combination therapy using antibody to human siglec-9 and antibody to human nkg2a for treating cancer |
CA3070297A1 (en) * | 2017-08-11 | 2019-02-14 | Genentech, Inc. | Anti-cd8 antibodies and uses thereof |
US10927180B2 (en) | 2017-10-13 | 2021-02-23 | Harpoon Therapeutics, Inc. | B cell maturation antigen binding proteins |
CN112135904A (zh) | 2018-01-03 | 2020-12-25 | 帕利昂制药有限公司 | 重组人唾液酸酶、唾液酸酶融合蛋白及其使用方法 |
US11912766B2 (en) | 2018-01-11 | 2024-02-27 | Allakos, Inc. | Anti-Siglec-7 antibodies having reduced effector function |
EP3802582A4 (en) * | 2018-06-07 | 2022-06-15 | Palleon Pharmaceuticals Inc. | MULTIMERIC PROTEINS FOR DETECTING A CARBOHYDRATE AND/OR TREATMENT OF A SIGLEC MEDIATED DISORDER |
EP3801767A1 (en) * | 2018-06-08 | 2021-04-14 | Alector LLC | Anti-siglec-7 antibodies and methods of use thereof |
KR20210086623A (ko) | 2018-09-25 | 2021-07-08 | 하푼 테라퓨틱스, 인크. | Ddl3 결합 단백질 및 사용 방법 |
WO2021024020A1 (en) | 2019-08-06 | 2021-02-11 | Astellas Pharma Inc. | Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer |
AU2020378251A1 (en) | 2019-11-04 | 2022-05-26 | Alector Llc | Siglec-9 ECD fusion molecules and methods of use thereof |
EP4172188A1 (en) * | 2020-06-30 | 2023-05-03 | The Board of Trustees of the Leland Stanford Junior University | Cis-binding siglec agonists and related compositions and methods |
JP2023532768A (ja) | 2020-07-07 | 2023-07-31 | バイオエヌテック エスエー | Hpv陽性癌の治療用rna |
WO2022135666A1 (en) | 2020-12-21 | 2022-06-30 | BioNTech SE | Treatment schedule for cytokine proteins |
TW202245808A (zh) | 2020-12-21 | 2022-12-01 | 德商拜恩迪克公司 | 用於治療癌症之治療性rna |
WO2022135667A1 (en) | 2020-12-21 | 2022-06-30 | BioNTech SE | Therapeutic rna for treating cancer |
KR20240046323A (ko) | 2021-07-13 | 2024-04-08 | 비온테크 에스이 | 암에 대한 병용 요법에 있어서 cd40 및 cd137에 대한 다중특이 결합제 |
TW202333802A (zh) | 2021-10-11 | 2023-09-01 | 德商拜恩迪克公司 | 用於肺癌之治療性rna(二) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002326531A1 (en) * | 2001-08-03 | 2003-02-17 | The Trustees Of The University Of Pennsylvania | Monoclonal antibodies to activated erbb family members and methods of use thereof |
JP2006265155A (ja) * | 2005-03-23 | 2006-10-05 | Link Genomics Kk | 癌の免疫療法 |
WO2014120642A1 (en) * | 2013-01-30 | 2014-08-07 | The General Hospital Corporation | Diagnosis and treatment of hepatorenal syndrome |
WO2016038064A1 (en) | 2014-09-10 | 2016-03-17 | Innate Pharma | Cross reactive siglec antibodies |
-
2015
- 2015-09-09 WO PCT/EP2015/070550 patent/WO2016038064A1/en active Application Filing
- 2015-09-09 US US15/509,859 patent/US20170306014A1/en not_active Abandoned
- 2015-09-09 EP EP15762562.5A patent/EP3191517B1/en not_active Revoked
- 2015-09-09 CA CA2957351A patent/CA2957351A1/en not_active Abandoned
- 2015-09-09 AU AU2015314316A patent/AU2015314316B2/en active Active
- 2015-09-09 MX MX2017002856A patent/MX2017002856A/es unknown
- 2015-09-09 JP JP2017513236A patent/JP2017532025A/ja active Pending
- 2015-09-09 DK DK15762562.5T patent/DK3191517T3/da active
-
2022
- 2022-04-11 JP JP2022065046A patent/JP2022109920A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DK3191517T3 (da) | 2021-01-25 |
CA2957351A1 (en) | 2016-03-17 |
EP3191517B1 (en) | 2020-11-04 |
JP2017532025A (ja) | 2017-11-02 |
AU2015314316B2 (en) | 2020-12-10 |
AU2015314316A1 (en) | 2017-03-09 |
JP2022109920A (ja) | 2022-07-28 |
US20170306014A1 (en) | 2017-10-26 |
WO2016038064A1 (en) | 2016-03-17 |
EP3191517A1 (en) | 2017-07-19 |
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