MX2017002140A - Metodo de pegilacion. - Google Patents

Metodo de pegilacion.

Info

Publication number
MX2017002140A
MX2017002140A MX2017002140A MX2017002140A MX2017002140A MX 2017002140 A MX2017002140 A MX 2017002140A MX 2017002140 A MX2017002140 A MX 2017002140A MX 2017002140 A MX2017002140 A MX 2017002140A MX 2017002140 A MX2017002140 A MX 2017002140A
Authority
MX
Mexico
Prior art keywords
pegylation method
pegylation
pegylating
relates
present
Prior art date
Application number
MX2017002140A
Other languages
English (en)
Inventor
S Gronke Robert
Jaquez Orlando
Original Assignee
Biogen Ma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Ma Inc filed Critical Biogen Ma Inc
Publication of MX2017002140A publication Critical patent/MX2017002140A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta

Abstract

La presente invención se relaciona a un método para pegilar interferon beta.
MX2017002140A 2014-08-19 2015-08-18 Metodo de pegilacion. MX2017002140A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461997000P 2014-08-19 2014-08-19
PCT/US2015/045678 WO2017030563A1 (en) 2014-08-19 2015-08-18 Pegylation method

Publications (1)

Publication Number Publication Date
MX2017002140A true MX2017002140A (es) 2017-08-21

Family

ID=59559468

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017002140A MX2017002140A (es) 2014-08-19 2015-08-18 Metodo de pegilacion.

Country Status (13)

Country Link
US (1) US11318207B2 (es)
EP (2) EP3183264B1 (es)
BR (1) BR112017003162A2 (es)
CO (1) CO2017002512A2 (es)
CY (1) CY1123685T1 (es)
DK (1) DK3183264T3 (es)
ES (1) ES2824028T3 (es)
HR (1) HRP20201725T1 (es)
LT (1) LT3183264T (es)
MX (1) MX2017002140A (es)
RS (1) RS61128B1 (es)
SI (1) SI3183264T1 (es)
WO (1) WO2017030563A1 (es)

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3710795A (en) 1970-09-29 1973-01-16 Alza Corp Drug-delivery device with stretched, rate-controlling membrane
EP0082481B2 (en) 1981-12-23 1990-09-12 Schering Corporation Stabilised alpha-interferon formulations and their preparation
US4766106A (en) 1985-06-26 1988-08-23 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polymer conjugation
US4917888A (en) 1985-06-26 1990-04-17 Cetus Corporation Solubilization of immunotoxins for pharmaceutical compositions using polymer conjugation
JP2514950B2 (ja) 1986-03-10 1996-07-10 エフ・ホフマン―ラ ロシユ アーゲー 化学修飾蛋白質，その製造法および中間体
US5595732A (en) 1991-03-25 1997-01-21 Hoffmann-La Roche Inc. Polyethylene-protein conjugates
US5262564A (en) 1992-10-30 1993-11-16 Octamer, Inc. Sulfinic acid adducts of organo nitroso compounds useful as retroviral inactivating agents anti-retroviral agents and anti-tumor agents
DK0730470T3 (da) 1993-11-10 2002-06-03 Enzon Inc Forbedrede interferonpolymerkonjugater
CN1187094C (zh) 1998-04-28 2005-02-02 应用研究系统Ars股份公司 多元醇干扰素β偶联物
TWI266801B (en) 1999-07-26 2006-11-21 Applied Research Systems Polyol-IFN-beta conjugates
GEP20074024B (en) * 2002-01-18 2007-01-10 Biogen Idec Inc Polyalkylene glycol comprising a radical for conjugation of biologically active compound
JP4237703B2 (ja) * 2002-09-27 2009-03-11 エフ．ホフマン−ラ ロシュ アーゲー インスリン様成長因子結合タンパク質−４及びポリ（エチレングリコール）の接合体
US20040180054A1 (en) 2003-03-13 2004-09-16 Hanmi Pharm. Co., Ltd. Physiologically active polypeptide conjugate having prolonged in vivo half-life
CU23556A1 (es) 2005-11-30 2010-07-20 Ct Ingenieria Genetica Biotech Estructura polimérica semejante a dendrímero para la obtención de conjugados de interés farmacéutico
GB0908393D0 (en) 2009-05-15 2009-06-24 Almac Sciences Scotland Ltd Labelling method
US20120258926A1 (en) * 2009-12-15 2012-10-11 Valentyn Antochshuk Formulations of acadesine
AR080993A1 (es) 2010-04-02 2012-05-30 Hanmi Holdings Co Ltd Formulacion de accion prolongada de interferon beta donde se usa un fragmento de inmunoglobulina
CN102453089B (zh) 2010-10-25 2014-06-04 北京凯因科技股份有限公司 重组集成干扰素变异体聚乙二醇偶联物的制备和应用
WO2014130811A1 (en) * 2013-02-22 2014-08-28 Biogen Idec Ma Inc Interferon beta formulation
CN103113466B (zh) 2013-03-01 2015-06-03 中国科学院过程工程研究所 聚乙二醇修饰的重组人干扰素β-1b及制备方法
CN103936847B (zh) 2013-12-24 2014-12-10 北京凯因科技股份有限公司 Peg-sa及其药物组合物

Also Published As

Publication number Publication date
SI3183264T1 (sl) 2021-03-31
BR112017003162A2 (pt) 2017-11-28
LT3183264T (lt) 2021-01-11
DK3183264T3 (da) 2020-11-02
EP3183264B1 (en) 2020-07-29
US20170232111A1 (en) 2017-08-17
EP3782652A1 (en) 2021-02-24
US11318207B2 (en) 2022-05-03
WO2017030563A1 (en) 2017-02-23
CY1123685T1 (el) 2022-03-24
WO2017030563A8 (en) 2017-03-16
CO2017002512A2 (es) 2017-05-31
HRP20201725T1 (hr) 2021-03-05
EP3183264A1 (en) 2017-06-28
ES2824028T3 (es) 2021-05-11
RS61128B1 (sr) 2020-12-31

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