MX2017001979A - Metodo y aparato in vitro para analizar el comportamiento de sustancias en ambiente fisiologico simulado. - Google Patents

Metodo y aparato in vitro para analizar el comportamiento de sustancias en ambiente fisiologico simulado.

Info

Publication number
MX2017001979A
MX2017001979A MX2017001979A MX2017001979A MX2017001979A MX 2017001979 A MX2017001979 A MX 2017001979A MX 2017001979 A MX2017001979 A MX 2017001979A MX 2017001979 A MX2017001979 A MX 2017001979A MX 2017001979 A MX2017001979 A MX 2017001979A
Authority
MX
Mexico
Prior art keywords
fluid
analysing
behaviour
substances
physiological environment
Prior art date
Application number
MX2017001979A
Other languages
English (en)
Inventor
Jagdish JERE Dhananjay
Christian MAHLER Hanns-
Patel Sulabh
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP14181653.8A external-priority patent/EP2988110A1/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2017001979A publication Critical patent/MX2017001979A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00—Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G01N33/559—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody through a gel, e.g. Ouchterlony technique
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00—Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G01N2013/003—Diffusion; diffusivity between liquids

Abstract

La presente invención se relaciona con un método y aparato in vitro para analizar el comportamiento de sustancias en un ambiente fisiológico simulado. El método comprende las etapas de proporcionar un primer fluido, una matriz de gel y un segundo fluido, separar el primer fluido y la matriz de gel mediante por al menos una primera membrana semipermeable y separar la matriz de gel y el segundo fluido mediante por al menos una segunda membrana semipermeable. El método además comprende las etapas de inyectar una sustancia en el primer fluido, dejar que la sustancia emigre desde el primer fluido a través de por lo menos un primera membrana semipermeable, a través de la matriz de gel, a través de por lo menos la segunda membrana semipermeable y en el segundo fluido, y determinar la depuración de la sustancia del primer fluido.
MX2017001979A 2014-08-20 2015-08-19 Metodo y aparato in vitro para analizar el comportamiento de sustancias en ambiente fisiologico simulado. MX2017001979A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14181653.8A EP2988110A1 (en) 2014-08-20 2014-08-20 In vitro method and apparatus for analysing the behaviour of substances in simulated physiological environment
EP15165825 2015-04-30
PCT/EP2015/068981 WO2016026877A1 (en) 2014-08-20 2015-08-19 In vitro method and apparatus for analysing the behaviour of substances in simulated physiological environment

Publications (1)

Publication Number Publication Date
MX2017001979A true MX2017001979A (es) 2017-05-04

Family

ID=54062716

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017001979A MX2017001979A (es) 2014-08-20 2015-08-19 Metodo y aparato in vitro para analizar el comportamiento de sustancias en ambiente fisiologico simulado.

Country Status (11)

Country Link
US (2) US10458891B2 (es)
EP (1) EP3183554B1 (es)
JP (2) JP6705808B2 (es)
KR (1) KR102354931B1 (es)
CN (1) CN106574887B (es)
BR (1) BR112017003167B1 (es)
CA (1) CA2957332A1 (es)
HK (1) HK1232297A1 (es)
MX (1) MX2017001979A (es)
RU (1) RU2694406C2 (es)
WO (1) WO2016026877A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112017003167B1 (pt) * 2014-08-20 2021-06-22 F. Hoffmann-La Roche Ag Método in vitro, aparelho para análise do comportamento de substâncias em ambiente fisiológico simulado e uso do mesmo
MY196292A (en) * 2016-01-28 2023-03-24 Chia Tai Tianqing Pharmaceutical Group Co Ltd Steroid Derivative Fxr Agonist
IT201800020242A1 (it) * 2018-12-19 2020-06-19 Milano Politecnico Substrato tridimensionale per le colture microbiche
DE102020101584A1 (de) * 2020-01-23 2021-07-29 Lts Lohmann Therapie-Systeme Ag Modifizierte Franz-Zelle
WO2023152254A1 (en) * 2022-02-11 2023-08-17 Lonza Ltd In-vitro method for simulating and analyzing behavior of an ophthalmological drug in an eye
WO2023230575A1 (en) * 2022-05-26 2023-11-30 University Of Kansas Emulator of subcutaneous absorption and release

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4740309A (en) * 1986-08-29 1988-04-26 Iprx, Inc. Methods and apparatus for determining the rate of movement of a study substance through a membrane
JPH03205017A (ja) * 1989-12-17 1991-09-06 Keiichi Kikuchi 容器型二重フィルターのコーヒーバッグ
US6821419B2 (en) 2002-01-28 2004-11-23 Hanson Research Corporation Diffusion cell with quick release clamp
CA2520439A1 (en) 2003-03-28 2004-10-07 Alza Corporation Static diffusion cell for diffusion sampling systems
TW200732644A (en) * 2005-10-25 2007-09-01 Rohm & Haas Dissolution test equipment and methods for testing having improved filtration system
CA2652173A1 (en) 2006-05-22 2007-11-29 Edward F. Leonard Systems and methods of microfluidic membraneless exchange using filtration of extraction fluid outlet streams
US8322193B2 (en) 2009-11-23 2012-12-04 Logan Instruments Corp. Transdermal diffusion cell testing arrangements and methods
GB201217675D0 (en) 2012-10-03 2012-11-14 Matharu Manmit S TTL adjustable binocular loupes device
GB201217768D0 (en) * 2012-10-04 2012-11-14 Univ Bath Methods and apparatus for the in vitro modelling of subcutaneous injection
BR112017003167B1 (pt) * 2014-08-20 2021-06-22 F. Hoffmann-La Roche Ag Método in vitro, aparelho para análise do comportamento de substâncias em ambiente fisiológico simulado e uso do mesmo

Also Published As

Publication number Publication date
HK1232297A1 (zh) 2018-01-05
KR20170046153A (ko) 2017-04-28
CN106574887A (zh) 2017-04-19
US20200025664A1 (en) 2020-01-23
CA2957332A1 (en) 2016-02-25
JP6993463B2 (ja) 2022-01-13
EP3183554B1 (en) 2019-02-20
US10458891B2 (en) 2019-10-29
BR112017003167B1 (pt) 2021-06-22
CN106574887B (zh) 2020-09-08
US10746644B2 (en) 2020-08-18
EP3183554A1 (en) 2017-06-28
US20170268976A1 (en) 2017-09-21
RU2694406C2 (ru) 2019-07-12
WO2016026877A1 (en) 2016-02-25
JP2017527797A (ja) 2017-09-21
KR102354931B1 (ko) 2022-01-24
JP6705808B2 (ja) 2020-06-03
BR112017003167A2 (pt) 2017-11-28
RU2017108426A (ru) 2018-09-20
JP2020126081A (ja) 2020-08-20
RU2017108426A3 (es) 2019-02-19

Similar Documents

Publication Publication Date Title
MX2017001979A (es) Metodo y aparato in vitro para analizar el comportamiento de sustancias en ambiente fisiologico simulado.
HK1254633A1 (zh) 用於分析樣品，尤其是血液，的裝置和系統以及使用它的方法
EP3435441A4 (en) INSULATING MEMBRANE FOR ELECTROCHEMICAL DEVICE, PRODUCTION METHOD AND APPLICATION THEREOF
EP3317428A4 (en) Method and system for diagnostic testing
EP3001196B8 (en) Blood testing system and method
EP3277294A4 (en) Method of identifying human compatible t cell receptors specific for an antigenic target
EP3149464A4 (en) System and method for electronic biological sample analysis
EP3248544A4 (en) Device for measuring concentration of substance in blood, and method for measuring concentration of substance in blood
EP3498160A4 (en) METHOD AND DEVICE FOR MEASURING BLOOD PRESSURE
EP3279655A4 (en) Method of preparing sample for analysis and analysis method
EP3093661A4 (en) Artificial cell membrane comprising supported lipid bilayer in which metal particle probe having controlled mobility is coupled, and method for analyzing molecular interaction by using same
HUE058186T2 (hu) Berendezés, eljárás és rendszer tenyésztett minták fejlõdésének felügyeletére
EP3421992A4 (en) CULTURE PATCH, CULTURE METHOD, CULTURE ANALYSIS METHOD AND APPARATUS, AND METHOD AND APPARATUS FOR TESTING A MEDICAMENT
EP3315061A4 (en) MEASURING SYSTEM AND METHOD FOR MEASURING BLOOD PRESSURE
EP3324325A4 (en) Method, client, and system for testing application
EP3240885A4 (en) STRUCTURED BIOLOGICAL SAMPLES FOR ANALYSIS BY A MASS CYTOMETER
EP3360469A4 (en) Apparatus for measuring blood pressure, and method for measuring blood pressure by using same
EP3470842A4 (en) MEMBRANE CARRIER FOR LIQUID SAMPLING TEST KIT, LIQUID SAMPLING TEST KIT AND METHOD FOR PRODUCING A LIQUID SAMPLING TEST KIT
EP3110196A4 (en) Method, apparatus and system for updating measurement identifier
EP3232778A4 (en) Systems, apparatus, and methods for analyzing blood cell dynamics
EP3100175A4 (en) Method and apparatus for social relation analysis and management
EP3325156A4 (en) DIAGNOSTIC TEST ASSEMBLY, APPARATUS, METHOD
IL263024A (en) Blood sample analysis method and system, for determining diabetes
EP3348998A4 (en) METHOD FOR QUANTITATIVE ANALYSIS AND ANALYSIS DEVICE FOR A POLYMER STRUCTURE
EP3525674A4 (en) METHOD AND DEVICE FOR THE OPTICAL MEASUREMENT OF THE BLOOD PRESSURE

Legal Events

Date Code Title Description
FG Grant or registration