MX2016015507A - Desaromatizacion oxidativa de berbinas. - Google Patents

Desaromatizacion oxidativa de berbinas.

Info

Publication number
MX2016015507A
MX2016015507A MX2016015507A MX2016015507A MX2016015507A MX 2016015507 A MX2016015507 A MX 2016015507A MX 2016015507 A MX2016015507 A MX 2016015507A MX 2016015507 A MX2016015507 A MX 2016015507A MX 2016015507 A MX2016015507 A MX 2016015507A
Authority
MX
Mexico
Prior art keywords
berbines
oxidative dearomatization
dearomatization
oxidative
oxidized
Prior art date
Application number
MX2016015507A
Other languages
English (en)
Inventor
w grote Christopher
Original Assignee
Mallinckrodt Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Llc filed Critical Mallinckrodt Llc
Publication of MX2016015507A publication Critical patent/MX2016015507A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

La presente invención proporciona derivados de berbina oxidados, procesos para su preparación, y métodos para usar los derivados de berbina oxidados.
MX2016015507A 2014-06-11 2015-06-11 Desaromatizacion oxidativa de berbinas. MX2016015507A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462010648P 2014-06-11 2014-06-11
PCT/US2015/035300 WO2015191837A1 (en) 2014-06-11 2015-06-11 Oxidative dearomatization of berbines

Publications (1)

Publication Number Publication Date
MX2016015507A true MX2016015507A (es) 2017-04-25

Family

ID=54834304

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016015507A MX2016015507A (es) 2014-06-11 2015-06-11 Desaromatizacion oxidativa de berbinas.

Country Status (9)

Country Link
US (1) US9593111B2 (es)
EP (1) EP3154968B1 (es)
JP (1) JP6577491B2 (es)
AU (1) AU2015274545B2 (es)
BR (1) BR112016027834B1 (es)
CA (1) CA2950768C (es)
ES (1) ES2813678T3 (es)
MX (1) MX2016015507A (es)
WO (1) WO2015191837A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3055307T3 (pl) * 2013-10-04 2020-07-27 SpecGx LLC Podstawione berbiny i ich synteza
WO2015191837A1 (en) 2014-06-11 2015-12-17 Mallinckrodt Llc Oxidative dearomatization of berbines

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5019781A (es) * 1973-06-25 1975-03-01
JPS5116698A (en) * 1974-07-27 1976-02-10 Kanebo Ltd Jibenzo * a*g * kinorijiniumujudotaino shinkigoseiho
US4033966A (en) * 1975-06-24 1977-07-05 Kanebo, Ltd. Novel berbine derivatives
KR100706309B1 (ko) * 2006-02-14 2007-04-12 한국생명공학연구원 항진균 활성이 우수한 베르베루빈 유도체
EP2331508B1 (en) * 2008-09-03 2014-11-12 Mallinckrodt LLC Substituted berbines and processes for their synthesis
CN101665491B (zh) * 2009-09-17 2011-09-28 长春工业大学 小檗碱13位衍生物和小檗红碱13位衍生物的合成方法
CN101798285B (zh) * 2010-02-10 2012-05-23 中国科学院上海有机化学研究所 一种青藤碱衍生物、合成方法及其用途
JOP20200043A1 (ar) 2011-05-10 2017-06-16 Amgen Inc طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول
CN102850346A (zh) * 2012-09-27 2013-01-02 四川大学 小檗红碱12-位衍生物及其制备方法和用途
WO2015191837A1 (en) 2014-06-11 2015-12-17 Mallinckrodt Llc Oxidative dearomatization of berbines

Also Published As

Publication number Publication date
ES2813678T3 (es) 2021-03-24
US20150361076A1 (en) 2015-12-17
AU2015274545A1 (en) 2016-12-15
EP3154968B1 (en) 2020-08-05
EP3154968A1 (en) 2017-04-19
CA2950768C (en) 2023-03-28
JP6577491B2 (ja) 2019-09-18
BR112016027834B1 (pt) 2023-12-26
WO2015191837A1 (en) 2015-12-17
AU2015274545B2 (en) 2019-02-28
JP2017518987A (ja) 2017-07-13
EP3154968A4 (en) 2018-02-07
BR112016027834A2 (es) 2017-08-22
CA2950768A1 (en) 2015-12-17
US9593111B2 (en) 2017-03-14

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GB Transfer or rights

Owner name: SPECGX LLC

FG Grant or registration