MX2016014731A - Tratamiento de las complicaciones de la enfermedad cronica del higado con enfermedades de caspasa. - Google Patents

Tratamiento de las complicaciones de la enfermedad cronica del higado con enfermedades de caspasa.

Info

Publication number
MX2016014731A
MX2016014731A MX2016014731A MX2016014731A MX2016014731A MX 2016014731 A MX2016014731 A MX 2016014731A MX 2016014731 A MX2016014731 A MX 2016014731A MX 2016014731 A MX2016014731 A MX 2016014731A MX 2016014731 A MX2016014731 A MX 2016014731A
Authority
MX
Mexico
Prior art keywords
treatment
complications
liver disease
caspase inhibitors
chronic liver
Prior art date
Application number
MX2016014731A
Other languages
English (en)
Spanish (es)
Inventor
P Spada Alfred
Original Assignee
Conatus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conatus Pharmaceuticals Inc filed Critical Conatus Pharmaceuticals Inc
Publication of MX2016014731A publication Critical patent/MX2016014731A/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/1825—Fibroblast growth factor [FGF]
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
MX2016014731A 2014-05-12 2015-05-11 Tratamiento de las complicaciones de la enfermedad cronica del higado con enfermedades de caspasa. MX2016014731A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461992169P 2014-05-12 2014-05-12
PCT/US2015/030101 WO2015175381A1 (en) 2014-05-12 2015-05-11 Treatment of the complications of chronic liver disease with caspase inhibitors

Publications (1)

Publication Number Publication Date
MX2016014731A true MX2016014731A (es) 2017-05-04

Family

ID=53276268

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016014731A MX2016014731A (es) 2014-05-12 2015-05-11 Tratamiento de las complicaciones de la enfermedad cronica del higado con enfermedades de caspasa.

Country Status (15)

Country Link
US (2) US20170100448A1 (https=)
EP (2) EP3142649B1 (https=)
JP (1) JP2017515854A (https=)
KR (1) KR20170015312A (https=)
CN (1) CN106470679A (https=)
AU (1) AU2015259471A1 (https=)
BR (1) BR112016026560A2 (https=)
CA (1) CA2948540A1 (https=)
ES (1) ES2751652T3 (https=)
IL (1) IL248882A0 (https=)
MX (1) MX2016014731A (https=)
RU (1) RU2016148364A (https=)
SG (1) SG11201609256SA (https=)
WO (1) WO2015175381A1 (https=)
ZA (1) ZA201607740B (https=)

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WO2017079566A1 (en) * 2015-11-05 2017-05-11 Conatus Pharmaceuticals, Inc. Caspase inhibitors for use in the treatment of liver cancer
JP2019500397A (ja) * 2015-12-31 2019-01-10 クオナトウス ファーマシューティカルズ，インコーポレイテッド カスパーゼ阻害剤を肝疾患の治療に使用する方法
FR3050112B1 (fr) 2016-04-15 2020-09-04 Soc Civ Immobiliere Gecinq Utilisation de l'acide fenofibrique dans le traitement des maladies hepatiques
TW201739734A (zh) 2016-05-11 2017-11-16 Chia Tai Tianqing Pharmaceutical Group Co Ltd Caspase抑制劑及其藥物組合物、用途和治療方法
WO2018148250A1 (en) * 2017-02-07 2018-08-16 The Regents Of The University Of California Methods for inhibiting nonalcoholic steatohepatitis, nonalcoholic fatty liver disease, and/or de novo lipogenesis
RU2020113234A (ru) * 2017-09-13 2021-10-13 Новартис Аг ПРИМЕНЕНИЕ АНТИТЕЛ, СВЯЗЫВАЮЩИХ IL-1β, ДЛЯ ЛЕЧЕНИЯ АЛКОГОЛЬНОГО ГЕПАТИТА
CN109748843B (zh) * 2017-11-06 2022-11-11 正大天晴药业集团股份有限公司 Caspase抑制剂及其药物组合物、用途和治疗方法
CA3102755A1 (en) * 2018-06-29 2020-01-02 The Doshisha Formulation containing emricasan
US11447497B2 (en) 2018-06-29 2022-09-20 Histogen, Inc. (S)-3-(2-(4-(benzyl)-3-oxopiperazin-1-yl)acetamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid derivatives and related compounds as caspase inhibitors for treating cardiovascular diseases
PL3935042T3 (pl) * 2019-03-07 2024-11-04 Nobo Medicine Inc. Inhibitory kaspazy i sposoby ich zastosowania
WO2020222541A1 (ko) * 2019-04-30 2020-11-05 주식회사 엘지화학 캐스파제 저해제의 프로드럭
US20230338459A1 (en) * 2020-04-14 2023-10-26 Amerimmune, Llc Treatment for Diseases Caused by RNA Viruses
MX2022013549A (es) 2020-05-01 2023-01-16 Medstar Health Inc Metodos para tratar la covid-19.
WO2022271877A2 (en) * 2021-06-22 2022-12-29 Amerimmune, Llc. Treatment for diseases caused by rna viruses

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