MX2016006571A - Aparatos y metodos de seleccion de anticuerpo. - Google Patents

Aparatos y metodos de seleccion de anticuerpo.

Info

Publication number
MX2016006571A
MX2016006571A MX2016006571A MX2016006571A MX2016006571A MX 2016006571 A MX2016006571 A MX 2016006571A MX 2016006571 A MX2016006571 A MX 2016006571A MX 2016006571 A MX2016006571 A MX 2016006571A MX 2016006571 A MX2016006571 A MX 2016006571A
Authority
MX
Mexico
Prior art keywords
methods
antibody
selection apparatus
antibody selection
articles
Prior art date
Application number
MX2016006571A
Other languages
English (en)
Inventor
Vikas K Sharma
E Swartz Trevor
W Patapoff Thomas
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2016006571A publication Critical patent/MX2016006571A/es

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/50—Molecular design, e.g. of drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
    • G16B35/20—Screening of libraries
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C10/00—Computational theoretical chemistry, i.e. ICT specially adapted for theoretical aspects of quantum chemistry, molecular mechanics, molecular dynamics or the like
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/60—In silico combinatorial chemistry
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

Aparatos, sistemas, medios legibles por computadora, artículos de manufactura y métodos para seleccionar un anticuerpo. Aparatos, sistemas, medios legibles por computadora, artículos de manufactura y métodos para producir el anticuerpo seleccionado. La selección puede incluir determinar una o más características fisicoquímicas del anticuerpo. La determinación puede basarse en parámetros estructurales del anticuerpo.
MX2016006571A 2013-11-29 2014-11-26 Aparatos y metodos de seleccion de anticuerpo. MX2016006571A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361910200P 2013-11-29 2013-11-29
PCT/US2014/067580 WO2015081176A2 (en) 2013-11-29 2014-11-26 Antibody selection apparatus and methods

Publications (1)

Publication Number Publication Date
MX2016006571A true MX2016006571A (es) 2016-08-05

Family

ID=52273498

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016006571A MX2016006571A (es) 2013-11-29 2014-11-26 Aparatos y metodos de seleccion de anticuerpo.

Country Status (9)

Country Link
US (2) US10861584B2 (es)
EP (1) EP3074772A2 (es)
JP (1) JP7156777B2 (es)
KR (1) KR102362002B1 (es)
CN (2) CN105793850B (es)
CA (1) CA2924448C (es)
MX (1) MX2016006571A (es)
RU (1) RU2742070C2 (es)
WO (1) WO2015081176A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4008003A1 (en) * 2019-08-02 2022-06-08 F. Hoffmann-La Roche AG Multipole moment based coarse grained representation of antibody electrostatics
CA3151337A1 (en) * 2019-08-20 2021-02-25 Regeneron Pharmaceuticals, Inc. Formulation optimization for bispecific antibodies
BR112022005654A2 (pt) * 2019-09-25 2022-07-19 Janssen Pharmaceuticals Inc Agregação remota de dados para dispositivos de administração de fármacos
US20220139558A1 (en) * 2020-11-02 2022-05-05 Regeneron Pharmaceuticals, Inc. Methods and systems for biotherapeutic development
CN112986206B (zh) * 2021-05-20 2021-07-30 北京百奥纳芯生物科技有限公司 一种检测基因芯片杂交结果的方法
WO2023107580A1 (en) * 2021-12-08 2023-06-15 The Johns Hopkins University Generative language models and related aspects for peptide and protein sequence design
WO2023222665A1 (en) * 2022-05-18 2023-11-23 Sanofi Method, system and apparatus for predicting pk values of antibodies

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6172213B1 (en) * 1997-07-02 2001-01-09 Genentech, Inc. Anti-IgE antibodies and method of improving polypeptides
AU2003291689A1 (en) * 2002-10-31 2004-05-25 Protein Design Labs, Inc. Stable liquid pharmaceutical formulation of antibodies that are prone to isomerization
ME00226B (me) * 2004-07-15 2011-02-10 Medarex Llc Humana anti-ngf neutrališuća antitijela kao selektivni inhibitori ngf signalne kaskade
CN101023101A (zh) * 2004-07-20 2007-08-22 西福根有限公司 抗－恒河猴d重组多克隆抗体和生产方法
SG170006A1 (en) * 2005-02-18 2011-04-29 Medarex Inc Monoclonal antibodies against cd30 lacking fucosyl residues
WO2007114319A1 (ja) * 2006-03-31 2007-10-11 Chugai Seiyaku Kabushiki Kaisha 抗体の血中動態を制御する方法
TWI614028B (zh) * 2007-06-14 2018-02-11 百健Ｍａ公司 抗體調配物
MY148637A (en) * 2007-09-28 2013-05-15 Chugai Pharmaceutical Co Ltd Anti-glypican-3 antibody having improved kinetics in plasma
US20130236448A1 (en) * 2009-08-04 2013-09-12 F. Hoffmann-La Roche Ag (Roche Glycart Ag) Concentrated polypeptide formulations with reduced viscosity
AU2011227335B2 (en) * 2010-03-17 2014-11-06 Abbott Research B.V. Anti-nerve growth factor (NGF) antibody compositions
AU2012328524B2 (en) * 2011-10-28 2017-05-18 Excelse Bio, Inc. Protein formulations containing amino acids
JP6294311B2 (ja) * 2012-05-23 2018-03-14 ジェネンテック， インコーポレイテッド 治療薬の選択方法
US10762980B2 (en) * 2013-05-17 2020-09-01 Massachusetts Institute Of Technology Computer-implemented methods of determining protein viscosity

Also Published As

Publication number Publication date
CN111402950B (zh) 2024-03-19
US10861584B2 (en) 2020-12-08
JP2020090504A (ja) 2020-06-11
RU2742070C2 (ru) 2021-02-02
KR102362002B1 (ko) 2022-02-10
JP7156777B2 (ja) 2022-10-19
CN111402950A (zh) 2020-07-10
CA2924448C (en) 2021-12-14
KR20160088318A (ko) 2016-07-25
EP3074772A2 (en) 2016-10-05
US20170091377A1 (en) 2017-03-30
JP2017512750A (ja) 2017-05-25
CN105793850B (zh) 2020-04-24
WO2015081176A3 (en) 2015-10-08
WO2015081176A2 (en) 2015-06-04
CA2924448A1 (en) 2015-06-04
US20210065843A1 (en) 2021-03-04
RU2016119424A (ru) 2018-01-09
CN105793850A (zh) 2016-07-20

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