MX2016004616A - Parches de células musculares y usos de los mismos. - Google Patents
Parches de células musculares y usos de los mismos.Info
- Publication number
- MX2016004616A MX2016004616A MX2016004616A MX2016004616A MX2016004616A MX 2016004616 A MX2016004616 A MX 2016004616A MX 2016004616 A MX2016004616 A MX 2016004616A MX 2016004616 A MX2016004616 A MX 2016004616A MX 2016004616 A MX2016004616 A MX 2016004616A
- Authority
- MX
- Mexico
- Prior art keywords
- contractile
- construct
- cells
- contractile cells
- disorder
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3826—Muscle cells, e.g. smooth muscle cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/367—Muscle tissue, e.g. sphincter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3873—Muscle tissue, e.g. sphincter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0062—General methods for three-dimensional culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/64—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/20—Materials or treatment for tissue regeneration for reconstruction of the heart, e.g. heart valves
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
- C12N2506/1315—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from cardiomyocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2513/00—3D culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2527/00—Culture process characterised by the use of mechanical forces, e.g. strain, vibration
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Developmental Biology & Embryology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Virology (AREA)
Abstract
Se divulgan estructura de células contráctiles que comprenden células contráctiles, o progenitores de las mismas, adheridas a una superficie de una matriz tridimensional que contiene fibroblastos (3 DEFCS) y métodos para usarlas para tratar enfermedades. En un aspecto, la presente invención proporciona métodos para preparar una estructura contráctil, que comprenden: (a) sembrar células contráctiles inmaduras en la superficie de una matriz tridimensional que contiene fibroblastos (3DECS9) para producir una estructura contráctil, y (b) cultivar la estructura contráctil bajo condiciones para promover la diferenciación de las células contráctiles inmaduras en células contráctiles maduras, en donde las células contráctiles maduras forman estrías. En otro aspecto más, la invención proporciona métodos pata tratar un trastorno caracterizado por una falta de células contráctiles funcionales, que comprende conectar a un paciente con un trastorno a base de células contráctiles con una cantidad efectiva para tratar el trastorno con la estructura de cualquier modalidad o combinación de modalidades de la invención.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361888882P | 2013-10-09 | 2013-10-09 | |
PCT/US2014/059688 WO2015054383A1 (en) | 2013-10-09 | 2014-10-08 | Muscle cell patches and uses therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2016004616A true MX2016004616A (es) | 2017-01-16 |
Family
ID=52813614
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2016004616A MX2016004616A (es) | 2013-10-09 | 2014-10-08 | Parches de células musculares y usos de los mismos. |
Country Status (7)
Country | Link |
---|---|
US (3) | US10172976B2 (es) |
EP (1) | EP3055028B1 (es) |
JP (4) | JP6509882B2 (es) |
AU (1) | AU2014331947B2 (es) |
CA (1) | CA2927062A1 (es) |
MX (1) | MX2016004616A (es) |
WO (1) | WO2015054383A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11299714B2 (en) * | 2015-05-11 | 2022-04-12 | The Trustees Of Columbia University In The City Of New York | Engineered adult-like human heart tissue |
WO2018013851A1 (en) | 2016-07-13 | 2018-01-18 | The Trustees Of Columbia University | Bioreactor system for engineering tissues |
US11890395B2 (en) | 2017-06-16 | 2024-02-06 | Avery Therapeutics, Inc. | Three dimensional tissue compositions and methods of use |
MX2020000118A (es) * | 2017-07-07 | 2020-08-06 | Univ Arizona | Composiciones y metodos para mejorar la funcion cardiaca. |
US11649424B2 (en) | 2017-07-28 | 2023-05-16 | The Trustees Of Columbia University In The City Of New York | Smart micro bioreactor platform for high throughput mechanical stimulation of cardiac microtissue |
WO2019222578A1 (en) * | 2018-05-18 | 2019-11-21 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for screening compounds for cardiac effects |
EP3741399A4 (en) * | 2018-07-27 | 2021-05-05 | Nagasaki University | LEAF-TYPE CELL CULTURE PRODUCT FOR GASTROINTESTINAL TRACT REGENERATION |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5283058A (en) | 1990-08-30 | 1994-02-01 | The General Hospital Corporation | Methods for inhibiting rejection of transplanted tissue |
CA2453438C (en) * | 2001-07-12 | 2016-04-05 | Geron Corporation | Cells of the cardiomyocyte lineage produced from human pluripotent stem cells |
US7993922B2 (en) * | 2002-10-18 | 2011-08-09 | Reliance Life Sciences Pvt. Ltd. | Three-dimensional tissue equivalent using macromass culture |
US20060216343A1 (en) | 2004-11-05 | 2006-09-28 | Steffen Panzner | Pharmaceutical compositions comprising an oligonucleotide as an active agent |
US20090169521A1 (en) * | 2007-12-31 | 2009-07-02 | Technion Research & Development Foundation Ltd. | Vascularized cardiac tissue and methods of producing and using same |
CA2758208A1 (en) * | 2009-04-09 | 2010-10-14 | Jordan Lancaster | Cellular seeding and co-culture of a three dimensional fibroblast construct |
EP2682462B1 (en) | 2011-02-28 | 2017-11-08 | Napajen Pharma, Inc. | (nucleic acid)-polysaccharide complex |
WO2013056019A1 (en) * | 2011-10-12 | 2013-04-18 | The Trustees Of The University Of Pennsylvania | In vitro microphysiological system for high throughput 3d tissue organization and biological function |
-
2014
- 2014-10-08 MX MX2016004616A patent/MX2016004616A/es unknown
- 2014-10-08 EP EP14852537.1A patent/EP3055028B1/en active Active
- 2014-10-08 US US15/028,606 patent/US10172976B2/en active Active
- 2014-10-08 WO PCT/US2014/059688 patent/WO2015054383A1/en active Application Filing
- 2014-10-08 JP JP2016547972A patent/JP6509882B2/ja active Active
- 2014-10-08 CA CA2927062A patent/CA2927062A1/en active Pending
- 2014-10-08 AU AU2014331947A patent/AU2014331947B2/en active Active
-
2018
- 2018-12-20 US US16/228,017 patent/US11020510B2/en active Active
-
2019
- 2019-04-03 JP JP2019071159A patent/JP2019141065A/ja active Pending
-
2021
- 2021-05-18 JP JP2021084104A patent/JP2021121206A/ja active Pending
- 2021-06-01 US US17/335,687 patent/US11980698B2/en active Active
-
2023
- 2023-06-28 JP JP2023106221A patent/JP2023123733A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2927062A1 (en) | 2015-04-16 |
JP2016536103A (ja) | 2016-11-24 |
US11020510B2 (en) | 2021-06-01 |
JP2021121206A (ja) | 2021-08-26 |
JP2019141065A (ja) | 2019-08-29 |
WO2015054383A1 (en) | 2015-04-16 |
US11980698B2 (en) | 2024-05-14 |
EP3055028A4 (en) | 2017-04-05 |
JP2023123733A (ja) | 2023-09-05 |
US20160250384A1 (en) | 2016-09-01 |
US10172976B2 (en) | 2019-01-08 |
EP3055028B1 (en) | 2024-01-03 |
EP3055028A1 (en) | 2016-08-17 |
AU2014331947A1 (en) | 2016-05-05 |
JP6509882B2 (ja) | 2019-05-08 |
AU2014331947B2 (en) | 2020-02-13 |
US20210290823A1 (en) | 2021-09-23 |
US20190142999A1 (en) | 2019-05-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2016004616A (es) | Parches de células musculares y usos de los mismos. | |
IL265470B (en) | A culture medium preparation, and a method for culturing cells or tissues by using the preparation | |
MX2015009190A (es) | Papel tisu absorbente. | |
EP2639293A4 (en) | CELL CULTURE CHAMBER, METHOD FOR PRODUCING THE SAME, FABRIC MODEL USING THE CELL CULTURE CHAMBER AND METHOD FOR PRODUCING THE SAME | |
BR112012019023A2 (pt) | método para produzir adenovírus recombinante sorotipo 26 (rad26), e, usoi de um biorreator | |
MX2016005658A (es) | Suspensión y agrupamiento de células madre humanas pluripotentes para la diferenciación a células endocrinas pancreáticas. | |
MX2016001986A (es) | Metodo para preparar rebaudiosido m mediante el uso de un metodo con enzima. | |
WO2013124817A3 (en) | MicroRNAS FOR THE GENERATION OF ASTROCYTES | |
ECSP13012869A (es) | Compuestos y métodos para la modulación de quinasas e indicaciones para los mismos | |
RU2014153529A (ru) | Дифференцировка эмбриональных стволовых клеток человека в панкреатические эндокринные клетки | |
EA201400993A1 (ru) | Антитела против рецептора эпидермального фактора роста, активные в определенных условиях, и способы их применения | |
TR201911199T4 (tr) | Hücre büyümesini arttırmak için tedavi. | |
EP2588592A4 (en) | USE OF PERFUSION DECELLULARIZED ORGANS FOR AGGREGATE RECELLULARIZATION | |
MY181513A (en) | Cell culture compositions and methods for polypeptide production | |
NZ609201A (en) | Means and methods for treating dlbcl | |
MX2013014307A (es) | Metodo de tratamiento de celulas madre mesenquinales y su uso en el tratamiento de enfermedades asociadas a estres oxidativo. | |
IN2015DN00934A (es) | ||
MX2015017863A (es) | Moduladores de receptor de hormona de crecimiento. | |
AR094389A1 (es) | USO DE INHIBIDORES DE iNOS PARA AUMENTAR EL RENDIMIENTO VÍRICO EN CULTIVOS | |
MX2015012875A (es) | Composiciones de cultivo celular con antioxidantes y metodos para la produccion de polipeptidos. | |
MX360824B (es) | Una combinación para inducir la formación de células beta de células de mamífero y uso de la misma. | |
BR112014019328A8 (pt) | Perfil de fenótipo de células progenitoras retinais humanas | |
EP2596097A4 (en) | MESENCHYMAL BONE MARROW STEM CELLS WITH HIGH TELOMERASE ACTIVITY, METHOD FOR THE PRODUCTION THEREOF, AND PHARMACEUTICALS AND TREATMENT METHODS ON THEIR BASIS | |
GB2523696A (en) | Methods of differentiating stem cells by modulating miR-124 | |
GB2508782A (en) | Facile laboratory method for localising biomolecules to the surface of cells and viruses |