MX2016003519A - Conjunto para un dispositivo de administracion de medicamento, y dispositivo de administracion de medicamento. - Google Patents

Conjunto para un dispositivo de administracion de medicamento, y dispositivo de administracion de medicamento.

Info

Publication number
MX2016003519A
MX2016003519A MX2016003519A MX2016003519A MX2016003519A MX 2016003519 A MX2016003519 A MX 2016003519A MX 2016003519 A MX2016003519 A MX 2016003519A MX 2016003519 A MX2016003519 A MX 2016003519A MX 2016003519 A MX2016003519 A MX 2016003519A
Authority
MX
Mexico
Prior art keywords
piston rod
drug
nut member
assembly
dose
Prior art date
Application number
MX2016003519A
Other languages
English (en)
Inventor
Michael Harms
Herbert Bechtold
Heiko Müller
Joachim Keitel
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49230599&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2016003519(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of MX2016003519A publication Critical patent/MX2016003519A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31556—Accuracy improving means
    • A61M5/31558—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31573—Accuracy improving means
    • A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button

Abstract

Se describe un conjunto para un dispositivo (1) de administración de medicamento, que comprende un cartucho (4), que contiene una pluralidad de dosis de un medicamento, y un vástago (9) de émbolo, configurado y dispuesto para expeler medicamento desde el cartucho (4) durante una operación de administración de medicamento del conjunto, de tal manera que el vástago (9) de émbolo comprende una rosca (9a). El conjunto comprende, adicionalmente, un miembro (13) de tuerca, de manera que el miembro (13) de tuerca está configurado y dispuesto para hacerse rotar con respecto al vástago (9) de émbolo alrededor de un eje de rotación (7) durante una operación de ajuste de dosis del conjunto, por lo que el miembro de tuerca (13) es axialmente desplazado a lo largo del vástago (9) de émbolo desde una posición de partida hasta una posición final con respecto al vástago (9) de émbolo, debido a una cooperación mecánica del miembro de tuerca (13) con la rosca (9a). El conjunto comprende, adicionalmente, un mecanismo de tope de última dosis, configurado y dispuesto para impedir a un usuario ajustar una dosis del medicamento que exceda una cantidad que queda de medicamento en el cartucho (4), de tal manera que el mecanismo de tope de última dosis comprende al menos un primer miembro de interacción (16) y al menos un segundo miembro de interacción (17), proporcionados por el vástago (9) de émbolo, y al menos un primer miembro de tope (18) y al menos un segundo miembro de tope (19), proporcionados por el miembro de tuerca (13), de tal modo que los miembros de interacción (16, 17) y los miembros de tope (18, 19) están configurados para cooperar mecánicamente entre sí cuando el miembro de tuerca (13) se encuentra en la posición final con respecto al vástago (9) de émbolo, de manera que se impide todo movimiento relativo adicional del miembro de tuerca (13) y el vástago (99 de émbolo para ajustar una dosis del medicamento. Se describe, además, un dispositivo (1) de administración de medicamento. Figura significativa: Fig. 11a.
MX2016003519A 2013-09-23 2014-09-17 Conjunto para un dispositivo de administracion de medicamento, y dispositivo de administracion de medicamento. MX2016003519A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13185478 2013-09-23
PCT/EP2014/069752 WO2015040039A1 (en) 2013-09-23 2014-09-17 Assembly for a drug delivery device and drug delivery device

Publications (1)

Publication Number Publication Date
MX2016003519A true MX2016003519A (es) 2016-07-05

Family

ID=49230599

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016003519A MX2016003519A (es) 2013-09-23 2014-09-17 Conjunto para un dispositivo de administracion de medicamento, y dispositivo de administracion de medicamento.

Country Status (17)

Country Link
US (1) US10569024B2 (es)
EP (1) EP3049131B1 (es)
JP (1) JP6722587B2 (es)
KR (1) KR102375565B1 (es)
CN (1) CN105579085B (es)
AR (1) AR097682A1 (es)
AU (1) AU2014323173B2 (es)
BR (1) BR112016005547B1 (es)
DK (1) DK3049131T3 (es)
ES (1) ES2831924T3 (es)
HU (1) HUE052236T2 (es)
IL (1) IL244225B (es)
MX (1) MX2016003519A (es)
PL (1) PL3049131T3 (es)
RU (1) RU2680922C2 (es)
TW (1) TWI655013B (es)
WO (1) WO2015040039A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115227910A (zh) * 2018-04-13 2022-10-25 迈德米斯瑞士股份公司 药剂输送装置
IT202100012020A1 (it) 2021-05-11 2022-11-11 Stevanato Group Spa Dispositivo di iniezione di un farmaco
IT202100032357A1 (it) 2021-12-23 2023-06-23 Stevanato Group Spa Dispositivo di iniezione di un farmaco

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US533575A (en) 1895-02-05 wilkens
DE3715258C2 (de) 1987-05-08 1996-10-31 Haselmeier Wilhelm Fa Injektionsgerät
GB8713810D0 (en) 1987-06-12 1987-07-15 Hypoguard Uk Ltd Measured dose dispensing device
US5226895A (en) 1989-06-05 1993-07-13 Eli Lilly And Company Multiple dose injection pen
GB9007113D0 (en) 1990-03-29 1990-05-30 Sams Bernard Dispensing device
US5226896A (en) 1990-04-04 1993-07-13 Eli Lilly And Company Dose indicating injection pen
AU641206B2 (en) 1991-01-22 1993-09-16 Eli Lilly And Company Multiple dose injection pen
ES2074771T3 (es) 1991-07-24 1995-09-16 Medico Dev Investment Co Inyector.
DK175491D0 (da) 1991-10-18 1991-10-18 Novo Nordisk As Apparat
US5279586A (en) 1992-02-04 1994-01-18 Becton, Dickinson And Company Reusable medication delivery pen
US5271527A (en) 1992-04-02 1993-12-21 Habley Medical Technology Corporation Reusable pharmaceutical dispenser with full stroke indicator
US5300041A (en) 1992-06-01 1994-04-05 Habley Medical Technology Corporation Dose setting and repeating syringe
US5391157A (en) 1992-10-20 1995-02-21 Eli Lilly And Company End of dose indicator
US5378233A (en) 1992-11-18 1995-01-03 Habley Medical Technology Corporation Selected dose pharmaceutical dispenser
US5320609A (en) 1992-12-07 1994-06-14 Habley Medical Technology Corporation Automatic pharmaceutical dispensing syringe
FR2701211B1 (fr) 1993-02-08 1995-05-24 Aguettant Lab Instrument doseur, notamment d'injection
US5383865A (en) 1993-03-15 1995-01-24 Eli Lilly And Company Medication dispensing device
ZA941881B (en) 1993-04-02 1995-09-18 Lilly Co Eli Manifold medication injection apparatus and method
US5582598A (en) 1994-09-19 1996-12-10 Becton Dickinson And Company Medication delivery pen with variable increment dose scale
CA2213682C (en) 1995-03-07 2009-10-06 Eli Lilly And Company Recyclable medication dispensing device
AU1860697A (en) 1995-09-08 1997-07-28 Visionary Medical Products Corporation Pen-type injector drive mechanism
US5674204A (en) 1995-09-19 1997-10-07 Becton Dickinson And Company Medication delivery pen cap actuated dose delivery clutch
US5688251A (en) 1995-09-19 1997-11-18 Becton Dickinson And Company Cartridge loading and priming mechanism for a pen injector
US5851079A (en) 1996-10-25 1998-12-22 The Procter & Gamble Company Simplified undirectional twist-up dispensing device with incremental dosing
DE19730999C1 (de) 1997-07-18 1998-12-10 Disetronic Licensing Ag Dosierknopfsicherung an einer Vorrichtung zur dosierten Verabreichung eines injizierbaren Produkts
US5957896A (en) 1997-08-11 1999-09-28 Becton, Dickinson And Company Medication delivery pen
EP1003581B1 (en) 1998-01-30 2000-11-08 Novo Nordisk A/S An injection syringe
US6221053B1 (en) 1998-02-20 2001-04-24 Becton, Dickinson And Company Multi-featured medication delivery pen
US5961495A (en) 1998-02-20 1999-10-05 Becton, Dickinson And Company Medication delivery pen having a priming mechanism
US6248095B1 (en) 1998-02-23 2001-06-19 Becton, Dickinson And Company Low-cost medication delivery pen
DE19900792C1 (de) 1999-01-12 2000-06-15 Disetronic Licensing Ag Vorrichtung zur Verabreichung eines injizierbaren Produkts
DE19900827C1 (de) 1999-01-12 2000-08-17 Disetronic Licensing Ag Vorrichtung zur dosierten Verabreichung eines injizierbaren Produkts
DE29900482U1 (de) 1999-01-14 2000-08-31 Medico Dev Investment Co Injektionsgerät
SE9901366D0 (sv) 1999-04-16 1999-04-16 Pharmacia & Upjohn Ab Injector device and method for its operation
AU6892100A (en) 1999-08-05 2001-03-05 Becton Dickinson & Company Medication delivery pen
GB0007071D0 (en) 2000-03-24 2000-05-17 Sams Bernard One-way clutch mechanisms and injector devices
US6663602B2 (en) 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
AU9258101A (en) 2000-10-09 2002-04-22 Lilly Co Eli Pen device for administration of parathyroid hormone
US6899699B2 (en) 2001-01-05 2005-05-31 Novo Nordisk A/S Automatic injection device with reset feature
EP2258425B1 (en) 2001-05-16 2013-01-30 Eli Lilly and Company Medication injector apparatus
EP1487520A1 (en) 2002-03-18 2004-12-22 Eli Lilly And Company Medication dispensing apparatus with gear set for mechanical advantage
CN100431631C (zh) 2002-10-01 2008-11-12 贝克顿·迪金森公司 药物输送笔
GB0304823D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
US6932794B2 (en) 2003-04-03 2005-08-23 Becton, Dickinson And Company Medication delivery pen
DK1689471T3 (da) 2003-10-16 2007-10-01 Lilly Co Eli Medikamentdispenseringsanordning med fast dosis
EP1541185A1 (en) 2003-12-08 2005-06-15 Novo Nordisk A/S Automatic syringe with priming mechanism
EP1804865B1 (en) * 2004-10-21 2009-09-30 Novo Nordisk A/S Dial-down mechanism for wind-up pen
KR20060059089A (ko) 2004-11-26 2006-06-01 삼성에스디아이 주식회사 Ｏｃｂ 모드 액정층을 구비하는 액정표시장치 및 그의제조방법
DE102004063644A1 (de) 2004-12-31 2006-07-20 Tecpharma Licensing Ag Vorrichtung zur dosierten Verabreichung eines fluiden Produkts mit Drehfederantrieb
DE602006004452D1 (de) 2005-02-11 2009-02-05 Novo Nordisk As Injektionsvorrichtung
US20090043264A1 (en) * 2005-04-24 2009-02-12 Novo Nordisk A/S Injection Device
ES2361563T5 (es) 2005-07-27 2016-03-22 Novo Nordisk A/S Mecanismo de dosificación para un dispositivo de inyección para limitar un ajuste de dosis que corresponde a la cantidad de medicamento restante
EP1923083A1 (en) 2006-11-17 2008-05-21 Sanofi-Aventis Deutschland GmbH Drive mechanisms for use in drug delivery devices
WO2009039851A1 (en) * 2007-09-25 2009-04-02 Claus Schmidt Moeller Dose delivery device with gearing mechanism
DE102008014995A1 (de) * 2008-03-05 2009-09-10 Schaeffler Kg Kugelgewindetrieb
US8647309B2 (en) 2008-05-02 2014-02-11 Sanofi-Aventis Deutschland Gmbh Medication delivery device
US8187233B2 (en) 2008-05-02 2012-05-29 Sanofi-Aventis Deutschland Gmbh Medication delivery device
US8366680B2 (en) 2008-12-12 2013-02-05 Sanofi-Aventis Deutschland Gmbh Resettable drive mechanism for a medication delivery device and medication delivery device
US8968258B2 (en) 2008-12-12 2015-03-03 Sanofi-Aventis Deutschland Gmbh Resettable drive mechanism for a medication delivery device and medication delivery device
MY159791A (en) * 2008-12-12 2017-01-31 Sanofi Aventis Deutschland Resettable drive mechanism for a medication delivery device and medication delivery device
WO2010072229A1 (de) 2008-12-22 2010-07-01 Tecpharma Licensing Ag Dosiervorrichtung für eine injektionsvorrichtung
MY156406A (en) * 2009-03-30 2016-02-26 Sanofi Aventis Deutschland Drug delivery device with an improved piston rod
US9199040B2 (en) * 2009-06-01 2015-12-01 Sanofi-Aventis Deutschland Gmbh Drug delivery device last dose lock-out mechanism
EP2501421B1 (en) * 2009-11-20 2019-08-21 Becton Dickinson and Company Injection device without a gearing
CH703909A2 (de) 2010-10-05 2012-04-13 Tecpharma Licensing Ag Mehrfach dosierbare Injektionsvorrichtung mit einer Zweikammerampulle.
EP2644217A1 (de) * 2012-03-30 2013-10-02 TecPharma Licensing AG Injektionsvorrichtung mit Dosisanzeige und Federantrieb

Also Published As

Publication number Publication date
ES2831924T3 (es) 2021-06-09
CN105579085B (zh) 2019-09-27
EP3049131B1 (en) 2020-10-21
WO2015040039A1 (en) 2015-03-26
PL3049131T3 (pl) 2021-04-19
JP6722587B2 (ja) 2020-07-15
EP3049131A1 (en) 2016-08-03
AU2014323173B2 (en) 2018-11-29
KR102375565B1 (ko) 2022-03-17
AR097682A1 (es) 2016-04-06
US10569024B2 (en) 2020-02-25
KR20160058831A (ko) 2016-05-25
IL244225B (en) 2022-06-01
JP2016530057A (ja) 2016-09-29
RU2016115745A3 (es) 2018-05-23
TWI655013B (zh) 2019-04-01
RU2680922C2 (ru) 2019-02-28
DK3049131T3 (da) 2021-01-11
HUE052236T2 (hu) 2021-04-28
CN105579085A (zh) 2016-05-11
IL244225A0 (en) 2016-04-21
BR112016005547B1 (pt) 2022-02-01
BR112016005547A2 (es) 2017-08-01
RU2016115745A (ru) 2017-10-30
US20160213852A1 (en) 2016-07-28
TW201545783A (zh) 2015-12-16
AU2014323173A1 (en) 2016-04-14

Similar Documents

Publication Publication Date Title
WO2016094387A3 (en) Versatile syringe platform
MX2013003340A (es) Mecanismo de engranaje para un dispositivo de suministro de dosis.
WO2013034985A3 (en) Reloadable auto-injector
EP3583966A3 (en) Single-use auto-injector
PH12020550780A1 (en) Devices and methods for precision dose delivery
MX2019015472A (es) Reduccion del impacto/choque de la activacion del mecanismo.
MX2017000203A (es) Dispositivo de administracion de farmacos.
HK1255593A1 (zh) 具有柱塞杆劑量控制機構的注射器
WO2010017285A3 (en) Multiple dosage injector
MX340391B (es) Dispositivos de suministro de medicamentos para la administración de un medicamento dentro de una jeringa precargada.
WO2013153041A3 (en) Infusion device
MX2015014289A (es) Mecanismo para controlar la velocidad de suministro y dispositivo de inyeccion.
BR112014019641A8 (pt) Dispositivo de injeção
WO2015090320A3 (en) Dose delivery device with improved handling
RU2016124541A (ru) Устройство с пружинным механизмом для доставки лекарственного средства
WO2014166907A3 (en) Drive mechanism for a drug delivery device
MY168387A (en) Improvements relating to medicament delivery devices
EP4011421A3 (en) Injection pen
MX2015014285A (es) Dispositivo de inyeccion.
WO2015047758A3 (en) Automatic self-dispensing accurate dose drug delivery syringes
WO2017148646A3 (en) ADMINISTRATION DEVICE
MX2016003519A (es) Conjunto para un dispositivo de administracion de medicamento, y dispositivo de administracion de medicamento.
MX2015014296A (es) Dispositivo de inyeccion.
TR201903870T4 (tr) Bir yardımcı tahriki içeren bir ilaç dağıtım cihazının tahrik mekanizması.
MX2015012118A (es) Conjunto para un dispositivo de administracion de farmacos.