MX2016001049A - Uso de flecainida como agente anti-conexina y metodo para potenciar los efectos de un farmaco psicotropico. - Google Patents

Uso de flecainida como agente anti-conexina y metodo para potenciar los efectos de un farmaco psicotropico.

Info

Publication number
MX2016001049A
MX2016001049A MX2016001049A MX2016001049A MX2016001049A MX 2016001049 A MX2016001049 A MX 2016001049A MX 2016001049 A MX2016001049 A MX 2016001049A MX 2016001049 A MX2016001049 A MX 2016001049A MX 2016001049 A MX2016001049 A MX 2016001049A
Authority
MX
Mexico
Prior art keywords
flecainide
connexin agent
potentiating
effects
psychotropic drug
Prior art date
Application number
MX2016001049A
Other languages
English (en)
Other versions
MX365782B (es
Inventor
Mouthon Franck
Charveriat Mathieu
Original Assignee
Commissariat Energie Atomique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique filed Critical Commissariat Energie Atomique
Publication of MX2016001049A publication Critical patent/MX2016001049A/es
Publication of MX365782B publication Critical patent/MX365782B/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4458Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41881,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

La presente invención se refiere al uso de flecainida como un agente anti-conexina; este agente anti-conexina se usa en forma ventajosa para potenciar el efecto terapéutico de varios fármacos psicotrópicos; más específicamente, la invención provee un producto de combinación que contiene flecainida y modafinil.
MX2016001049A 2013-07-24 2014-07-24 Uso de flecainida como un agente anti-conexina y método para potenciar los efectos de un fármaco psicotrópico. MX365782B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13306074 2013-07-24
PCT/EP2014/065975 WO2015011246A1 (en) 2013-07-24 2014-07-24 Use of flecainide as an anti-connexin agent and method for potentiating the effects of a psychotropic drug

Publications (2)

Publication Number Publication Date
MX2016001049A true MX2016001049A (es) 2016-08-12
MX365782B MX365782B (es) 2019-06-13

Family

ID=48900920

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016001049A MX365782B (es) 2013-07-24 2014-07-24 Uso de flecainida como un agente anti-conexina y método para potenciar los efectos de un fármaco psicotrópico.
MX2019006878A MX2019006878A (es) 2013-07-24 2016-01-22 Uso de flecainida como un agente anti-conexina y metodo para potenciar los efectos de un farmaco psicotropico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2019006878A MX2019006878A (es) 2013-07-24 2016-01-22 Uso de flecainida como un agente anti-conexina y metodo para potenciar los efectos de un farmaco psicotropico.

Country Status (20)

Country Link
US (3) US9750734B2 (es)
EP (2) EP3308785A3 (es)
JP (3) JP6192830B2 (es)
KR (2) KR20170068629A (es)
CN (1) CN105579041B (es)
AU (1) AU2014295030B2 (es)
BR (1) BR112016001446A8 (es)
CA (2) CA2919140C (es)
DK (1) DK3024458T3 (es)
ES (1) ES2661647T3 (es)
HR (1) HRP20180487T1 (es)
HU (1) HUE037122T2 (es)
IL (2) IL243746A (es)
MX (2) MX365782B (es)
PL (1) PL3024458T3 (es)
PT (1) PT3024458T (es)
RU (2) RU2018122564A (es)
TR (1) TR201802302T4 (es)
WO (1) WO2015011246A1 (es)
ZA (1) ZA201601146B (es)

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CA2992162A1 (en) * 2015-07-15 2017-01-19 Theranexus Use of amitriptyline for blocking brain hemichannels and method for potentiating its effect in vivo
US10744087B2 (en) 2018-03-22 2020-08-18 Incarda Therapeutics, Inc. Method to slow ventricular rate
WO2019204326A1 (en) * 2018-04-16 2019-10-24 Alsar Ltd Partnership Compositions and methods for sustained release of flecainide
US20210255198A1 (en) * 2018-06-11 2021-08-19 The United States of America as Represented by the Department of Veterans Affairs Office Methods for objective assessment of stress, early detection of risk for stress disorders, matching individuals with treatments, monitoring response to treatment, and new methods of use for drugs
US20190381056A1 (en) 2018-06-17 2019-12-19 Axsome Therapeutics, Inc. Compositions for delivery of reboxetine
EP3593822A1 (en) 2018-07-13 2020-01-15 Theranexus Therapeutic and diagnostic applications of a new method of monitoring of neuroglial interaction memri)
US11020402B2 (en) 2018-10-15 2021-06-01 Axsome Therapeutics, Inc. Use of reboxetine to treat narcolepsy
US20200147093A1 (en) 2018-10-15 2020-05-14 Axsome Therapeutics, Inc. Use of esreboxetine to treat nervous system disorders such as fibromyalgia
US11021410B2 (en) * 2018-12-10 2021-06-01 Purdue Research Foundation Layer-wise agglomerated urea granules
US11020384B2 (en) 2019-08-01 2021-06-01 Incarda Therapeutics, Inc. Antiarrhythmic formulation
WO2021025985A1 (en) * 2019-08-02 2021-02-11 Praxis Precision Medicines, Inc. Methods of treating substance abuse disorder, dyspnea, tinnitus, and child and adolescent depression
CN111018694A (zh) * 2019-12-12 2020-04-17 贵州省欣紫鸿药用辅料有限公司 一种氟卡尼的生产方法
CN116096900A (zh) * 2020-05-13 2023-05-09 阿库斯股份有限公司 用于治疗gjb2相关听力损失的组合物和方法
KR102390194B1 (ko) * 2020-08-03 2022-04-25 셀라이온바이오메드 주식회사 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물
WO2022170081A1 (en) * 2021-02-05 2022-08-11 Incarda Therapeutics, Inc. Antiarrhythmic formulation

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JP2001253825A (ja) 2000-03-13 2001-09-18 Masahiko Ichimada 帯状疱疹後神経痛用鎮痛剤
US7799832B2 (en) * 2003-10-23 2010-09-21 Valeant Pharmaceuticals North America Combinations of retigabine and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains
KR20080067628A (ko) * 2005-11-21 2008-07-21 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 알라바마 포 앤드 온 비하프 오브 더 유니버시티 오브 알라바마 신경보호를 위한 소분자 화합물의 사용 방법
JP5960944B2 (ja) * 2006-11-15 2016-08-02 コーダ セラピューティクス, インコーポレイテッド 創傷治癒のための改善された方法および組成物
FR2935611B1 (fr) * 2008-09-10 2010-10-15 Commissariat Energie Atomique Utilisation d'agents anti-connexines pour moduler l'effet therapeutique de molecules psychotropes
WO2012042541A2 (en) 2010-09-30 2012-04-05 Council Of Scientific & Industrial Research Method for predicting and modeling anti-psychotic activity using virtual screening model
US20130096067A1 (en) 2011-09-14 2013-04-18 Norbert Perrimon Drosophila tumor stem cell model and uses thereof
EP2586436A1 (en) * 2011-10-31 2013-05-01 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Use of anti-connexin agents for enhancing the therapeutic effect of acetylcholinesterase inhibitor

Also Published As

Publication number Publication date
IL243746A (en) 2017-09-28
US9750734B2 (en) 2017-09-05
EP3308785A2 (en) 2018-04-18
AU2014295030A1 (en) 2016-02-25
JP6453931B2 (ja) 2019-01-16
PL3024458T3 (pl) 2018-08-31
US20160158213A1 (en) 2016-06-09
MX365782B (es) 2019-06-13
US20190008844A1 (en) 2019-01-10
US20180028519A1 (en) 2018-02-01
WO2015011246A1 (en) 2015-01-29
DK3024458T3 (en) 2018-02-19
MX2019006878A (es) 2019-08-01
EP3308785A3 (en) 2018-07-18
CA2997282A1 (en) 2015-01-29
CA2919140C (en) 2018-05-01
BR112016001446A2 (pt) 2017-08-29
RU2018122564A (ru) 2019-03-06
IL254210A0 (en) 2017-10-31
EP3024458A1 (en) 2016-06-01
EP3024458B1 (en) 2018-01-03
RU2016105971A (ru) 2017-08-25
KR101754045B1 (ko) 2017-07-05
CN105579041A (zh) 2016-05-11
JP6192830B2 (ja) 2017-09-06
TR201802302T4 (tr) 2018-03-21
JP2019059773A (ja) 2019-04-18
HRP20180487T1 (hr) 2018-05-04
JP2017119710A (ja) 2017-07-06
ES2661647T3 (es) 2018-04-02
CN105579041B (zh) 2019-04-19
BR112016001446A8 (pt) 2018-01-23
KR20160058760A (ko) 2016-05-25
PT3024458T (pt) 2018-04-11
US10639301B2 (en) 2020-05-05
CA2919140A1 (en) 2015-01-29
IL243746A0 (en) 2016-04-21
AU2014295030B2 (en) 2017-06-01
HUE037122T2 (hu) 2018-08-28
KR20170068629A (ko) 2017-06-19
ZA201601146B (en) 2017-11-29
IL254210B (en) 2021-10-31
JP2016525140A (ja) 2016-08-22
JP6694497B2 (ja) 2020-05-13
RU2661026C2 (ru) 2018-07-11

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