MX2015012431A - Pirrol amida como inhibidores. - Google Patents

Pirrol amida como inhibidores.

Info

Publication number
MX2015012431A
MX2015012431A MX2015012431A MX2015012431A MX2015012431A MX 2015012431 A MX2015012431 A MX 2015012431A MX 2015012431 A MX2015012431 A MX 2015012431A MX 2015012431 A MX2015012431 A MX 2015012431A MX 2015012431 A MX2015012431 A MX 2015012431A
Authority
MX
Mexico
Prior art keywords
pyrrole amide
amide inhibitors
compounds
formula
inhibitors
Prior art date
Application number
MX2015012431A
Other languages
English (en)
Inventor
John K Pratt
Steven W Elmore
Keith F Mcdaniel
Dachun Liu
George S Sheppard
Lisa A Hasvold
Robert D Hubbard
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of MX2015012431A publication Critical patent/MX2015012431A/es

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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Abstract

La presente invención proporciona compuestos de fórmula (I) (ver Fórmula) en donde R1, R2, R3, y R10 tienen cualquiera de los valores definidos en la especificación, y las sales farmacéuticamente aceptables de los mismos, que son útiles como agentes en el tratamiento de enfermedades y condiciones, incluyendo enfermedades inflamatorias, cáncer, y SIDA. También se proporcionan composiciones farmacéuticas que comprenden uno o más compuestos de fórmula (I).
MX2015012431A 2013-03-12 2014-03-12 Pirrol amida como inhibidores. MX2015012431A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361777749P 2013-03-12 2013-03-12
PCT/US2014/024508 WO2014165127A1 (en) 2013-03-12 2014-03-12 Pyrrole amide inhibitors

Publications (1)

Publication Number Publication Date
MX2015012431A true MX2015012431A (es) 2016-05-31

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MX2015012431A MX2015012431A (es) 2013-03-12 2014-03-12 Pirrol amida como inhibidores.

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US (1) US9493411B2 (es)
EP (1) EP2970193B1 (es)
JP (1) JP2016512542A (es)
CN (1) CN105164113B (es)
AU (1) AU2014248647A1 (es)
BR (1) BR112015022551A2 (es)
CA (1) CA2905426A1 (es)
MX (1) MX2015012431A (es)
WO (1) WO2014165127A1 (es)

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US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
WO2014080290A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Cyclic amines as bromodomain inhibitors
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