MX2015011576A - Composiciones que comprenden compuestos de tienopirimidina y tienopiridina y metodos para usar los mismos. - Google Patents

Composiciones que comprenden compuestos de tienopirimidina y tienopiridina y metodos para usar los mismos.

Info

Publication number
MX2015011576A
MX2015011576A MX2015011576A MX2015011576A MX2015011576A MX 2015011576 A MX2015011576 A MX 2015011576A MX 2015011576 A MX2015011576 A MX 2015011576A MX 2015011576 A MX2015011576 A MX 2015011576A MX 2015011576 A MX2015011576 A MX 2015011576A
Authority
MX
Mexico
Prior art keywords
thienopyrimidine
methods
compositions
thienopyridine compounds
mll1
Prior art date
Application number
MX2015011576A
Other languages
English (en)
Spanish (es)
Inventor
Jolanta Grembecka
Thomasz Cierpicki
Dmitry Borkin
Jay Hess
Duxin Sun
Xiaoqin Li
Original Assignee
Univ Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan filed Critical Univ Michigan
Publication of MX2015011576A publication Critical patent/MX2015011576A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/16—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Epidemiology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2015011576A 2013-03-13 2014-03-10 Composiciones que comprenden compuestos de tienopirimidina y tienopiridina y metodos para usar los mismos. MX2015011576A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361780099P 2013-03-13 2013-03-13
PCT/US2014/022750 WO2014164543A1 (en) 2013-03-13 2014-03-10 Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof

Publications (1)

Publication Number Publication Date
MX2015011576A true MX2015011576A (es) 2016-05-16

Family

ID=51529943

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015011576A MX2015011576A (es) 2013-03-13 2014-03-10 Composiciones que comprenden compuestos de tienopirimidina y tienopiridina y metodos para usar los mismos.

Country Status (11)

Country Link
US (4) US9216993B2 (cg-RX-API-DMAC7.html)
EP (1) EP2968342B1 (cg-RX-API-DMAC7.html)
JP (2) JP2016512514A (cg-RX-API-DMAC7.html)
KR (1) KR20150130389A (cg-RX-API-DMAC7.html)
CN (1) CN105188705A (cg-RX-API-DMAC7.html)
AU (1) AU2014249233A1 (cg-RX-API-DMAC7.html)
BR (1) BR112015022602A2 (cg-RX-API-DMAC7.html)
CA (1) CA2904612A1 (cg-RX-API-DMAC7.html)
IL (1) IL241193A0 (cg-RX-API-DMAC7.html)
MX (1) MX2015011576A (cg-RX-API-DMAC7.html)
WO (1) WO2014164543A1 (cg-RX-API-DMAC7.html)

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EP4643952A2 (en) * 2016-01-26 2025-11-05 Memorial Sloan Kettering Cancer Center Targeting chromatin regulators for inhibiting leukemogenic gene expression in npm1
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WO2017207387A1 (en) 2016-05-31 2017-12-07 Bayer Pharma Aktiengesellschaft Spiro condensed azetidine derivatives as inhibitors of the menin-mml1 interaction
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WO2018183857A1 (en) 2017-03-31 2018-10-04 The Regents Of The University Of Michigan Piperidines as covalent menin inhibitors
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CN110204552B (zh) * 2018-02-28 2021-08-17 中国科学院上海药物研究所 一类噻吩并[3,2-d]嘧啶衍生物、其制备方法、药物组合物与用途
RS63124B1 (sr) 2018-03-08 2022-05-31 Incyte Corp Aminopirazin diol jedinjenja kao pi3k-y inhibitori
JP7239562B2 (ja) * 2018-03-30 2023-03-14 住友ファーマ株式会社 光学活性な架橋型環状２級アミン誘導体
WO2020010003A1 (en) 2018-07-02 2020-01-09 Incyte Corporation AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS
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SG11202104243VA (en) * 2018-12-06 2021-05-28 Daiichi Sankyo Co Ltd Cycloalkane-1,3-diamine derivative
ES2974634T3 (es) 2018-12-21 2024-06-28 Celgene Corp Inhibidores de tienopiridinas de RIPK2
US11572369B2 (en) * 2019-02-01 2023-02-07 University Of South Carolina Bicyclic pyridine compositions and methods of using the same for cancer therapy
SG11202113129UA (en) 2019-05-31 2021-12-30 Ikena Oncology Inc Tead inhibitors and uses thereof
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Also Published As

Publication number Publication date
BR112015022602A2 (pt) 2017-07-18
US9505782B2 (en) 2016-11-29
US20160137665A1 (en) 2016-05-19
JP2016512514A (ja) 2016-04-28
US9216993B2 (en) 2015-12-22
WO2014164543A1 (en) 2014-10-09
EP2968342A4 (en) 2016-07-27
EP2968342A1 (en) 2016-01-20
CN105188705A (zh) 2015-12-23
KR20150130389A (ko) 2015-11-23
JP2018115214A (ja) 2018-07-26
US20140275070A1 (en) 2014-09-18
US10160769B2 (en) 2018-12-25
IL241193A0 (en) 2015-11-30
US20170253611A1 (en) 2017-09-07
AU2014249233A1 (en) 2015-09-24
JP6670885B2 (ja) 2020-03-25
EP2968342B1 (en) 2018-10-03
US9505781B2 (en) 2016-11-29
CA2904612A1 (en) 2014-10-09
US20160046647A1 (en) 2016-02-18

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