MX2015010029A - Medicamento profilactico o terapeutico para el estreñimiento. - Google Patents
Medicamento profilactico o terapeutico para el estreñimiento.Info
- Publication number
- MX2015010029A MX2015010029A MX2015010029A MX2015010029A MX2015010029A MX 2015010029 A MX2015010029 A MX 2015010029A MX 2015010029 A MX2015010029 A MX 2015010029A MX 2015010029 A MX2015010029 A MX 2015010029A MX 2015010029 A MX2015010029 A MX 2015010029A
- Authority
- MX
- Mexico
- Prior art keywords
- therapeutic drug
- constipation
- prophylactic
- drug
- useful
- Prior art date
Links
- 206010010774 Constipation Diseases 0.000 title abstract 2
- 229940126585 therapeutic drug Drugs 0.000 title abstract 2
- 229940043274 prophylactic drug Drugs 0.000 title 1
- 230000000069 prophylactic effect Effects 0.000 title 1
- -1 4-isopropylphenyl glucitol compound Chemical class 0.000 abstract 1
- 108091006277 SLC5A1 Proteins 0.000 abstract 1
- 102000058090 Sodium-Glucose Transporter 1 Human genes 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se proveen nuevos fármacos útiles en la prevención o tratamiento del estreñimiento, en los que están contenidos como ingredientes activos compuestos inhibidores de SGLT1, en particular un compuesto de 4-isopropilfenil glucitol representado por la siguiente fórmula (I), o sales farmacéuticamente aceptables de los mismos. (ver Fórmula).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013019754 | 2013-02-04 | ||
PCT/JP2014/052465 WO2014119787A1 (ja) | 2013-02-04 | 2014-02-03 | 便秘症の予防又は治療薬 |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015010029A true MX2015010029A (es) | 2015-10-30 |
MX346453B MX346453B (es) | 2017-03-17 |
Family
ID=51262485
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015010029A MX346453B (es) | 2013-02-04 | 2014-02-03 | Medicamento profilactico o terapeutico para el estreñimiento. |
Country Status (18)
Country | Link |
---|---|
US (1) | US10022389B2 (es) |
EP (1) | EP2952206B1 (es) |
JP (1) | JP5807767B2 (es) |
KR (1) | KR102078433B1 (es) |
CN (1) | CN104955481B (es) |
AU (1) | AU2014213251B2 (es) |
BR (1) | BR112015017541A2 (es) |
CA (1) | CA2899834C (es) |
ES (1) | ES2694110T3 (es) |
HK (1) | HK1211479A1 (es) |
IL (1) | IL240192A (es) |
MX (1) | MX346453B (es) |
MY (1) | MY176162A (es) |
PH (1) | PH12015501696A1 (es) |
RU (1) | RU2648467C2 (es) |
SG (2) | SG11201506047PA (es) |
TW (1) | TWI659739B (es) |
WO (1) | WO2014119787A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2019142774A (ja) * | 2016-06-20 | 2019-08-29 | 大正製薬株式会社 | 腸内環境改善剤 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2830424C3 (de) | 1978-07-11 | 1982-04-15 | Bayer Ag, 5090 Leverkusen | alpha -Glucosidase-Inhibitoren |
US5651988A (en) | 1995-08-18 | 1997-07-29 | Xyrofin Oy | Combination osmotic and bulk forming laxatives |
ATE469161T1 (de) | 2002-08-08 | 2010-06-15 | Kissei Pharmaceutical | Pyrazolderivat, dieses enthaltende medizinische zusammensetzung, medizinische verwendung davon, und zwischenprodukt für dessen herstellung |
JP2004137245A (ja) | 2002-08-23 | 2004-05-13 | Kissei Pharmaceut Co Ltd | ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体 |
AU2003262262A1 (en) | 2002-08-27 | 2004-03-19 | Kissei Pharmaceutical Co., Ltd. | Pyrazole derivatives, medicinal composition containing the same, and medicinal use thereof |
CN1744916A (zh) | 2002-12-04 | 2006-03-08 | 橘生药品工业株式会社 | 预防和治疗高血糖所导致的疾病 |
DE102004028241B4 (de) | 2004-06-11 | 2007-09-13 | Sanofi-Aventis Deutschland Gmbh | Neue Fluorglykosidderivate von Pyrazolen, diese Verbindungen enthaltende Arzneimittel und Herstellung dieser Arzneimittel |
TWI387454B (zh) | 2004-09-02 | 2013-03-01 | Sucampo Ag | 治療胃腸道疾病之方法及組成物 |
JP5067644B2 (ja) | 2006-05-19 | 2012-11-07 | 大正製薬株式会社 | C−フェニルグリシト−ル化合物 |
JP5152519B2 (ja) | 2006-06-29 | 2013-02-27 | 大正製薬株式会社 | C−フェニル1−チオグルシト−ル化合物 |
TW200817424A (en) | 2006-08-04 | 2008-04-16 | Daiichi Sankyo Co Ltd | Benzylphenyl glucopyranoside derivatives |
TWI499414B (zh) | 2006-09-29 | 2015-09-11 | Lexicon Pharmaceuticals Inc | 鈉與葡萄糖第2型共同運輸體(co-transporter 2)的抑制物與其應用方法 |
CA2672176A1 (en) | 2006-12-14 | 2008-06-19 | Taisho Pharmaceutical Co., Ltd. | 1-phenyl 1-thio-d-glucitol derivative |
GB2447067A (en) | 2007-02-20 | 2008-09-03 | Branko R Babic | Alteration of osmotic gradients by polyhydroxy compounds |
CA2709530C (en) | 2007-12-27 | 2016-02-23 | Kissei Pharmaceutical Co., Ltd. | Monosebacate of pyrazole derivative |
JP5467040B2 (ja) | 2008-04-16 | 2014-04-09 | キッセイ薬品工業株式会社 | ピラゾール誘導体の1/2フマル酸塩 |
WO2010095768A1 (en) * | 2009-02-23 | 2010-08-26 | Taisho Pharmaceutical Co., Ltd. | 4 -isopropylphenyl glucitol compounds as sgltl inhibitors |
JP2013224263A (ja) | 2010-08-19 | 2013-10-31 | Taisho Pharmaceutical Co Ltd | 4−イソプロピルフェニルグルシトール化合物 |
JP5656092B2 (ja) | 2010-08-20 | 2015-01-21 | 大正製薬株式会社 | 4−イソプロピルフェニルグルシトール化合物の結晶形及びその製造方法 |
JP5532138B2 (ja) | 2010-08-20 | 2014-06-25 | 大正製薬株式会社 | 4−イソプロピル−6−メトキシフェニルグルシトール化合物 |
AR087701A1 (es) * | 2011-08-31 | 2014-04-09 | Japan Tobacco Inc | Derivados de pirazol con actividad inhibidora de sglt1 |
BR112014027841B1 (pt) | 2012-05-07 | 2022-08-09 | Kissei Pharmaceutical Co., Ltd | Uso de derivados de pirazola na fabricação de um fármaco para prevenir ou tratar constipação |
US9200025B2 (en) | 2012-11-20 | 2015-12-01 | Lexicon Pharmaceuticals, Inc. | Inhibitors of sodium glucose cotransporter 1 |
-
2014
- 2014-02-03 KR KR1020157018999A patent/KR102078433B1/ko active IP Right Grant
- 2014-02-03 CA CA2899834A patent/CA2899834C/en active Active
- 2014-02-03 AU AU2014213251A patent/AU2014213251B2/en not_active Ceased
- 2014-02-03 CN CN201480007190.8A patent/CN104955481B/zh not_active Expired - Fee Related
- 2014-02-03 EP EP14746685.8A patent/EP2952206B1/en active Active
- 2014-02-03 RU RU2015137671A patent/RU2648467C2/ru active
- 2014-02-03 MY MYPI2015702526A patent/MY176162A/en unknown
- 2014-02-03 MX MX2015010029A patent/MX346453B/es active IP Right Grant
- 2014-02-03 JP JP2014526017A patent/JP5807767B2/ja not_active Expired - Fee Related
- 2014-02-03 WO PCT/JP2014/052465 patent/WO2014119787A1/ja active Application Filing
- 2014-02-03 ES ES14746685.8T patent/ES2694110T3/es active Active
- 2014-02-03 SG SG11201506047PA patent/SG11201506047PA/en unknown
- 2014-02-03 SG SG10201700267PA patent/SG10201700267PA/en unknown
- 2014-02-03 US US14/765,134 patent/US10022389B2/en active Active
- 2014-02-03 BR BR112015017541A patent/BR112015017541A2/pt not_active Application Discontinuation
- 2014-02-05 TW TW103103751A patent/TWI659739B/zh not_active IP Right Cessation
-
2015
- 2015-07-28 IL IL240192A patent/IL240192A/en active IP Right Grant
- 2015-07-31 PH PH12015501696A patent/PH12015501696A1/en unknown
- 2015-12-15 HK HK15112295.0A patent/HK1211479A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
TW201517903A (zh) | 2015-05-16 |
MX346453B (es) | 2017-03-17 |
HK1211479A1 (en) | 2016-05-27 |
SG11201506047PA (en) | 2015-09-29 |
IL240192A0 (en) | 2015-09-24 |
KR20150112949A (ko) | 2015-10-07 |
AU2014213251A1 (en) | 2015-08-27 |
JPWO2014119787A1 (ja) | 2017-01-26 |
RU2648467C2 (ru) | 2018-03-26 |
CA2899834A1 (en) | 2014-08-07 |
CN104955481B (zh) | 2017-10-24 |
AU2014213251B2 (en) | 2017-07-20 |
KR102078433B1 (ko) | 2020-02-17 |
EP2952206A4 (en) | 2016-06-15 |
CA2899834C (en) | 2020-09-01 |
PH12015501696B1 (en) | 2015-10-12 |
PH12015501696A1 (en) | 2015-10-12 |
TWI659739B (zh) | 2019-05-21 |
ES2694110T3 (es) | 2018-12-18 |
US10022389B2 (en) | 2018-07-17 |
SG10201700267PA (en) | 2017-02-27 |
IL240192A (en) | 2017-03-30 |
US20150374735A1 (en) | 2015-12-31 |
WO2014119787A1 (ja) | 2014-08-07 |
EP2952206A1 (en) | 2015-12-09 |
EP2952206B1 (en) | 2018-10-24 |
CN104955481A (zh) | 2015-09-30 |
JP5807767B2 (ja) | 2015-11-10 |
RU2015137671A (ru) | 2017-03-10 |
MY176162A (en) | 2020-07-24 |
BR112015017541A2 (pt) | 2017-07-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |