MX2015009445A - Metodos de uso de compuestos de fenoxipropilamina para tratar la depresion. - Google Patents
Metodos de uso de compuestos de fenoxipropilamina para tratar la depresion.Info
- Publication number
- MX2015009445A MX2015009445A MX2015009445A MX2015009445A MX2015009445A MX 2015009445 A MX2015009445 A MX 2015009445A MX 2015009445 A MX2015009445 A MX 2015009445A MX 2015009445 A MX2015009445 A MX 2015009445A MX 2015009445 A MX2015009445 A MX 2015009445A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- formula
- disclosed
- methods
- compound
- Prior art date
Links
- DXVQSHRBALIFBC-UHFFFAOYSA-N 3-phenoxypropan-1-amine Chemical class NCCCOC1=CC=CC=C1 DXVQSHRBALIFBC-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 7
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102100022738 5-hydroxytryptamine receptor 1A Human genes 0.000 abstract 1
- 101710138638 5-hydroxytryptamine receptor 1A Proteins 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 230000003467 diminishing effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
En este documento se divulgan composiciones y métodos para tratar la depresión usando composiciones que comprenden un compuesto de la Fórmula I. Se divulgan composiciones y métodos para tratar la depresión usando composiciones que comprenden compuestos de fenoxipropilamina y derivados que tienen afinidad selectiva para y actividad antagonista contra el receptor de 5-HT1A, así como la actividad inhibidora de la recaptación de 5-HT. Además, se divulgan composiciones y métodos para tratar la depresión mediante composiciones que comprenden un compuesto de la Fórmula II. También se divulgan métodos para tratar o disminuir al menos un síntoma de la depresión en un sujeto humano con una composición que comprende un compuesto de la Fórmula (I) o la Fórmula (II), o una sal farmacéuticamente aceptable, hidrato o solvato de la misma,.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361756208P | 2013-01-24 | 2013-01-24 | |
| US201361799482P | 2013-03-15 | 2013-03-15 | |
| US201361852149P | 2013-03-15 | 2013-03-15 | |
| PCT/US2014/013026 WO2014117003A1 (en) | 2013-01-24 | 2014-01-24 | Use of phenoxypropylamine compounds to treat depression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015009445A true MX2015009445A (es) | 2016-01-14 |
Family
ID=51208168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015009445A MX2015009445A (es) | 2013-01-24 | 2014-01-24 | Metodos de uso de compuestos de fenoxipropilamina para tratar la depresion. |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US20140206722A1 (es) |
| EP (2) | EP3925608A3 (es) |
| JP (2) | JP6422890B2 (es) |
| KR (4) | KR102587177B1 (es) |
| CN (2) | CN105377255A (es) |
| AU (4) | AU2014209200B2 (es) |
| BR (1) | BR112015017628A2 (es) |
| CA (2) | CA2898279C (es) |
| CL (1) | CL2015002069A1 (es) |
| DK (1) | DK2948143T3 (es) |
| ES (1) | ES2875058T3 (es) |
| IL (4) | IL287727B2 (es) |
| MX (1) | MX2015009445A (es) |
| MY (1) | MY185908A (es) |
| NZ (2) | NZ750189A (es) |
| PE (1) | PE20151888A1 (es) |
| PH (1) | PH12015501643B1 (es) |
| PL (1) | PL2948143T3 (es) |
| PT (1) | PT2948143T (es) |
| RU (2) | RU2725112C2 (es) |
| SG (2) | SG11201505737YA (es) |
| WO (1) | WO2014117003A1 (es) |
| ZA (2) | ZA201505114B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190013847A (ko) * | 2016-05-25 | 2019-02-11 | 미쓰비시 타나베 파마 코퍼레이션 | 불안 장애를 치료하기 위한 (2S)-1-[4-(3,4-디클로로페닐)피페리딘-1-일]-3-[2-(5-메틸-1,3,4-옥사디아졸-2-일)벤조[b]푸란-4-일옥시]프로판-2-올 또는 그의 대사산물 |
| US11541201B2 (en) * | 2017-10-04 | 2023-01-03 | Neurogeneces, Inc. | Sleep performance system and method of use |
| US11766430B2 (en) | 2018-09-04 | 2023-09-26 | Minerva Neurosciences, Inc. | Methods of using a phenoxypropylamine compound to treat pain |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4207343A (en) * | 1978-06-22 | 1980-06-10 | Eli Lilly And Company | 1-Phenyl-3-(substituted phenoxy)propylamines |
| KR100882544B1 (ko) * | 1999-05-24 | 2009-02-12 | 미쓰비시 타나베 파마 코퍼레이션 | 페녹시프로필아민 화합물 |
| US6784180B2 (en) * | 1999-12-20 | 2004-08-31 | Eli Lilly And Company | Piperidines derivatives and their use as serotonin receptor antagonists |
| RU2424799C1 (ru) * | 2010-03-29 | 2011-07-27 | Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ ФЕДЕРАЛЬНОГО АГЕНТСТВА ПО ЗДРАВООХРАНЕНИЮ И СОЦИАЛЬНОМУ РАЗВИТИЮ" | Способ коррекции депрессивных расстройств производными тиетан-1,1-диоксида в эксперименте |
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2014
- 2014-01-24 PT PT147431589T patent/PT2948143T/pt unknown
- 2014-01-24 MX MX2015009445A patent/MX2015009445A/es unknown
- 2014-01-24 US US14/163,827 patent/US20140206722A1/en not_active Abandoned
- 2014-01-24 PL PL14743158T patent/PL2948143T3/pl unknown
- 2014-01-24 DK DK14743158.9T patent/DK2948143T3/da active
- 2014-01-24 SG SG11201505737YA patent/SG11201505737YA/en unknown
- 2014-01-24 MY MYPI2015001864A patent/MY185908A/en unknown
- 2014-01-24 IL IL287727A patent/IL287727B2/en unknown
- 2014-01-24 CA CA2898279A patent/CA2898279C/en active Active
- 2014-01-24 SG SG10201706035QA patent/SG10201706035QA/en unknown
- 2014-01-24 CA CA3150231A patent/CA3150231A1/en active Pending
- 2014-01-24 NZ NZ750189A patent/NZ750189A/en unknown
- 2014-01-24 EP EP21171312.8A patent/EP3925608A3/en active Pending
- 2014-01-24 KR KR1020227026625A patent/KR102587177B1/ko active IP Right Grant
- 2014-01-24 RU RU2015135358A patent/RU2725112C2/ru active
- 2014-01-24 ES ES14743158T patent/ES2875058T3/es active Active
- 2014-01-24 EP EP14743158.9A patent/EP2948143B1/en active Active
- 2014-01-24 KR KR1020157022424A patent/KR102172351B1/ko active IP Right Grant
- 2014-01-24 PE PE2015001552A patent/PE20151888A1/es not_active Application Discontinuation
- 2014-01-24 AU AU2014209200A patent/AU2014209200B2/en active Active
- 2014-01-24 CN CN201480017774.3A patent/CN105377255A/zh active Pending
- 2014-01-24 RU RU2020120236A patent/RU2020120236A/ru unknown
- 2014-01-24 WO PCT/US2014/013026 patent/WO2014117003A1/en active Application Filing
- 2014-01-24 KR KR1020207019380A patent/KR102247960B1/ko active IP Right Grant
- 2014-01-24 BR BR112015017628A patent/BR112015017628A2/pt not_active Application Discontinuation
- 2014-01-24 NZ NZ709967A patent/NZ709967A/en unknown
- 2014-01-24 IL IL311363A patent/IL311363A/en unknown
- 2014-01-24 KR KR1020217011567A patent/KR20210047368A/ko active Application Filing
- 2014-01-24 JP JP2015555358A patent/JP6422890B2/ja active Active
- 2014-01-24 CN CN201910816861.XA patent/CN110664813A/zh active Pending
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2015
- 2015-07-14 IL IL239928A patent/IL239928B/en active IP Right Grant
- 2015-07-16 ZA ZA2015/05114A patent/ZA201505114B/en unknown
- 2015-07-24 CL CL2015002069A patent/CL2015002069A1/es unknown
- 2015-07-24 PH PH12015501643A patent/PH12015501643B1/en unknown
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2018
- 2018-06-19 JP JP2018116163A patent/JP6657315B2/ja active Active
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2019
- 2019-01-25 AU AU2019200512A patent/AU2019200512B2/en active Active
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2020
- 2020-03-25 US US16/829,657 patent/US20200223838A1/en not_active Abandoned
- 2020-07-15 AU AU2020205268A patent/AU2020205268B2/en active Active
- 2020-10-18 IL IL278109A patent/IL278109B/en unknown
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2022
- 2022-07-07 ZA ZA2022/07530A patent/ZA202207530B/en unknown
- 2022-09-26 AU AU2022241458A patent/AU2022241458A1/en active Pending
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