MX2015004362A - Derivados de ketamina. - Google Patents
Derivados de ketamina.Info
- Publication number
- MX2015004362A MX2015004362A MX2015004362A MX2015004362A MX2015004362A MX 2015004362 A MX2015004362 A MX 2015004362A MX 2015004362 A MX2015004362 A MX 2015004362A MX 2015004362 A MX2015004362 A MX 2015004362A MX 2015004362 A MX2015004362 A MX 2015004362A
- Authority
- MX
- Mexico
- Prior art keywords
- ketamine derivatives
- methods
- derivatives
- ketamine
- formula
- Prior art date
Links
- YQEZLKZALYSWHR-UHFFFAOYSA-N Ketamine Chemical class C=1C=CC=C(Cl)C=1C1(NC)CCCCC1=O YQEZLKZALYSWHR-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/14—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of carbon skeletons containing rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ60288512 | 2012-10-08 | ||
| NZ61120213 | 2013-05-28 | ||
| PCT/IB2013/059191 WO2014057414A1 (en) | 2012-10-08 | 2013-10-08 | Ketamine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015004362A true MX2015004362A (es) | 2015-12-08 |
Family
ID=50476991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015004362A MX2015004362A (es) | 2012-10-08 | 2013-10-08 | Derivados de ketamina. |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20150259277A1 (enEXAMPLES) |
| EP (1) | EP2903963A4 (enEXAMPLES) |
| JP (2) | JP6309957B2 (enEXAMPLES) |
| KR (1) | KR20150065873A (enEXAMPLES) |
| CN (1) | CN104837810B (enEXAMPLES) |
| AU (1) | AU2013328280B2 (enEXAMPLES) |
| BR (1) | BR112015007647A2 (enEXAMPLES) |
| CA (1) | CA2922340A1 (enEXAMPLES) |
| EA (1) | EA201590697A1 (enEXAMPLES) |
| HK (1) | HK1212673A1 (enEXAMPLES) |
| IN (1) | IN2015DN03854A (enEXAMPLES) |
| MX (1) | MX2015004362A (enEXAMPLES) |
| WO (1) | WO2014057414A1 (enEXAMPLES) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201590697A1 (ru) * | 2012-10-08 | 2015-09-30 | Окленд Юнисервисиз Лимитед | Производные кетамина |
| US20160332962A1 (en) * | 2015-05-13 | 2016-11-17 | Janssen Pharmaceutica Nv | (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine |
| CA2987909C (en) | 2015-06-27 | 2022-04-26 | Shenox Pharmaceuticals, Llc | Ketamine transdermal delivery system |
| US11111210B2 (en) | 2015-11-18 | 2021-09-07 | Spirify Pharma Inc. | Phenyl cyclohexanone derivatives and methods of making and using them |
| US11827606B2 (en) | 2015-11-18 | 2023-11-28 | Spirify Pharma Inc. | Phenyl cyclohexanone derivatives and methods of making and using them |
| JP7603368B2 (ja) * | 2016-03-25 | 2024-12-20 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | （２ｒ，６ｒ）－ヒドロキシノルケタミン塩酸塩の結晶形態 |
| KR20230110828A (ko) | 2018-01-10 | 2023-07-25 | 엑스더블유파마 리미티드 | 케타민의 전구약물, 및 이의 조성물 및 용도 |
| EP3761970A4 (en) * | 2018-03-26 | 2022-06-08 | Cellix Bio Private Limited | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISEASES |
| CN112424157B (zh) * | 2018-06-04 | 2024-02-20 | 美国政府健康及人类服务部 | 用于合成和纯化(2r,6r)-羟基去甲氯胺酮的方法 |
| CN112125816A (zh) * | 2020-03-17 | 2020-12-25 | 国药集团工业有限公司 | 一种氯胺酮、其衍生物或其盐的消旋化方法 |
| DE102021105268A1 (de) * | 2021-03-04 | 2022-09-08 | Lts Lohmann Therapie-Systeme Ag. | Oraler Dünnfilm |
| EP4559522A3 (en) | 2021-08-13 | 2025-07-16 | XWPharma Ltd. | Pharmaceutical compositions and oral dosage forms of ketamine derivatives |
| CN115677444A (zh) * | 2022-10-26 | 2023-02-03 | 公安部第三研究所 | 同位素毒品代谢物标记化合物及其制备方法、用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3254124A (en) * | 1962-06-29 | 1966-05-31 | Parke Davis & Co | Aminoketones and methods for their production |
| GB1134146A (en) * | 1967-09-15 | 1968-11-20 | Parke Davis & Co | New organic amines and methods for their production |
| US5019583A (en) | 1989-02-15 | 1991-05-28 | Glaxo Inc. | N-phenyl-N-(4-piperidinyl)amides useful as analgesics |
| US5466700A (en) | 1993-08-30 | 1995-11-14 | Glaxo Wellcome Inc. | Anesthetic use of N-phenyl-N-(4-piperidinyl)amides |
| US5866591A (en) | 1996-09-11 | 1999-02-02 | Glaxo Wellcome Inc. | Stable formulations of remifentanil |
| CA2397831A1 (en) * | 2000-01-28 | 2001-08-02 | Rohm And Haas Company | Enhanced propertied pharmaceuticals |
| US20040248963A1 (en) | 2001-11-23 | 2004-12-09 | Bueno Melendo Ana Belen | Prodrugs of excitatory amino acids |
| EP1333023B1 (en) * | 2002-01-31 | 2010-12-22 | Randox Laboratories Ltd. | Immunogens, antibodies and conjugates to ketamine and its metabolites |
| DE60327883D1 (de) * | 2002-11-18 | 2009-07-16 | Yaupon Therapeutics Inc | Analgetische verwendung von (s)-norketamin |
| PT1928405E (pt) * | 2005-09-28 | 2014-10-20 | Auris Medical Ag | Composições farmacêuticas para o tratamento de distúrbios do ouvido interno |
| BRPI0809843A2 (pt) * | 2007-04-26 | 2014-09-23 | Auspex Pharmaceuticals Inc | "composto, composição farmacêutica e uso de um composto" |
| CA2851619C (en) | 2011-10-14 | 2021-12-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | The use of hydroxynorketamine, dehydronorketamine and other ketamine metabolites in the treatment of depression and neuropathic pain |
| EA201590697A1 (ru) * | 2012-10-08 | 2015-09-30 | Окленд Юнисервисиз Лимитед | Производные кетамина |
-
2013
- 2013-10-08 EA EA201590697A patent/EA201590697A1/ru unknown
- 2013-10-08 WO PCT/IB2013/059191 patent/WO2014057414A1/en active Application Filing
- 2013-10-08 EP EP13846133.0A patent/EP2903963A4/en not_active Withdrawn
- 2013-10-08 IN IN3854DEN2015 patent/IN2015DN03854A/en unknown
- 2013-10-08 AU AU2013328280A patent/AU2013328280B2/en not_active Ceased
- 2013-10-08 KR KR1020157012009A patent/KR20150065873A/ko not_active Ceased
- 2013-10-08 US US14/433,957 patent/US20150259277A1/en not_active Abandoned
- 2013-10-08 CN CN201380061537.2A patent/CN104837810B/zh not_active Expired - Fee Related
- 2013-10-08 CA CA2922340A patent/CA2922340A1/en not_active Abandoned
- 2013-10-08 JP JP2015535162A patent/JP6309957B2/ja not_active Expired - Fee Related
- 2013-10-08 BR BR112015007647A patent/BR112015007647A2/pt not_active Application Discontinuation
- 2013-10-08 MX MX2015004362A patent/MX2015004362A/es unknown
- 2013-10-08 HK HK16100661.0A patent/HK1212673A1/zh unknown
-
2017
- 2017-03-20 US US15/463,532 patent/US10239825B2/en not_active Expired - Fee Related
-
2018
- 2018-03-14 JP JP2018046540A patent/JP2018127466A/ja active Pending
-
2019
- 2019-02-06 US US16/269,015 patent/US20190169113A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2903963A1 (en) | 2015-08-12 |
| EP2903963A4 (en) | 2016-05-25 |
| CN104837810B (zh) | 2019-08-06 |
| IN2015DN03854A (enEXAMPLES) | 2015-10-02 |
| JP6309957B2 (ja) | 2018-04-11 |
| US20150259277A1 (en) | 2015-09-17 |
| US10239825B2 (en) | 2019-03-26 |
| WO2014057414A9 (en) | 2014-12-18 |
| HK1212673A1 (zh) | 2016-06-17 |
| US20190169113A1 (en) | 2019-06-06 |
| AU2013328280B2 (en) | 2017-12-21 |
| WO2014057414A1 (en) | 2014-04-17 |
| JP2018127466A (ja) | 2018-08-16 |
| BR112015007647A2 (pt) | 2017-07-04 |
| CA2922340A1 (en) | 2014-04-17 |
| CN104837810A (zh) | 2015-08-12 |
| KR20150065873A (ko) | 2015-06-15 |
| US20170190653A1 (en) | 2017-07-06 |
| EA201590697A1 (ru) | 2015-09-30 |
| JP2015535847A (ja) | 2015-12-17 |
| AU2013328280A1 (en) | 2015-05-14 |
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