MX2014015744A - Anticuerpos a-beta de epítopo de terminal c y central. - Google Patents
Anticuerpos a-beta de epítopo de terminal c y central.Info
- Publication number
- MX2014015744A MX2014015744A MX2014015744A MX2014015744A MX2014015744A MX 2014015744 A MX2014015744 A MX 2014015744A MX 2014015744 A MX2014015744 A MX 2014015744A MX 2014015744 A MX2014015744 A MX 2014015744A MX 2014015744 A MX2014015744 A MX 2014015744A
- Authority
- MX
- Mexico
- Prior art keywords
- antibody
- cdr
- seq
- amino acid
- acid sequence
- Prior art date
Links
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Mycology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261667891P | 2012-07-03 | 2012-07-03 | |
| PCT/US2013/046399 WO2014007982A2 (en) | 2012-07-03 | 2013-06-18 | C-terminal and central epitope a-beta antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2014015744A true MX2014015744A (es) | 2015-06-05 |
Family
ID=49882576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014015744A MX2014015744A (es) | 2012-07-03 | 2013-06-18 | Anticuerpos a-beta de epítopo de terminal c y central. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20150353631A1 (enExample) |
| EP (1) | EP2869846A4 (enExample) |
| JP (1) | JP2015526409A (enExample) |
| KR (1) | KR20150036163A (enExample) |
| CN (1) | CN105579061A (enExample) |
| AU (1) | AU2013287119A1 (enExample) |
| BR (1) | BR112014033066A2 (enExample) |
| CA (1) | CA2877516A1 (enExample) |
| HK (1) | HK1208810A1 (enExample) |
| IL (1) | IL236549A0 (enExample) |
| MX (1) | MX2014015744A (enExample) |
| RU (1) | RU2014153675A (enExample) |
| WO (1) | WO2014007982A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3702373T (pt) | 2013-09-13 | 2022-09-27 | Beigene Switzerland Gmbh | Anticorpos anti-pd1 e a sua utilização como agentes terapêuticos e de diagnóstico |
| CN110156892B (zh) | 2014-07-03 | 2023-05-16 | 百济神州有限公司 | 抗pd-l1抗体及其作为治疗剂及诊断剂的用途 |
| SG10201900571YA (en) | 2014-07-22 | 2019-02-27 | Cb Therapeutics Inc | Anti-pd-1 antibodies |
| SG10201901057UA (en) | 2014-08-05 | 2019-03-28 | Cb Therapeutics Inc | Anti-pd-l1 antibodies |
| US20180344881A1 (en) * | 2015-11-20 | 2018-12-06 | Navidea Biopharmaceuticals, Inc. | Formulations for 2-heteroaryl substituted benzofurans |
| EP3397276A4 (en) * | 2015-12-30 | 2019-12-18 | Kodiak Sciences Inc. | ANTIBODIES AND CONJUGATES THEREOF |
| CN105542005B (zh) * | 2016-02-03 | 2018-11-09 | 大连理工大学 | 一种抗人淀粉样β肽的纳米抗体及其应用 |
| US10864203B2 (en) | 2016-07-05 | 2020-12-15 | Beigene, Ltd. | Combination of a PD-1 antagonist and a RAF inhibitor for treating cancer |
| CN110087680B (zh) | 2016-08-19 | 2024-03-19 | 百济神州有限公司 | 使用包含btk抑制剂的组合产品治疗癌症 |
| TWI774726B (zh) | 2017-01-25 | 2022-08-21 | 英屬開曼群島商百濟神州有限公司 | (S)-7-(1-(丁-2-炔醯基)哌啶-4-基)-2-(4-苯氧基苯基)-4,5,6,7-四氫吡唑并[1,5-a]嘧啶-3-甲醯胺的晶型、及其製備和用途 |
| KR102757960B1 (ko) | 2017-06-26 | 2025-01-22 | 베이진 엘티디 | 간세포암(hepatocellular carcinoma: HCC)에 대한 면역 치료 |
| WO2019108795A1 (en) | 2017-11-29 | 2019-06-06 | Beigene Switzerland Gmbh | Treatment of indolent or aggressive b-cell lymphomas using a combination comprising btk inhibitors |
| JP2023535024A (ja) | 2020-07-23 | 2023-08-15 | オター プロシーナ リミテッド | 抗ａベータ抗体 |
| EP4448564A1 (en) | 2021-12-17 | 2024-10-23 | F. Hoffmann-La Roche AG | A novel antibody for detection of amyloid beta 42 (a-beta42) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1014996T3 (da) * | 1997-08-28 | 2003-09-29 | Univ Washington | Præparater indeholdende saccharid til behandling af Alzheimers sygdom og andre amyloidoser |
| US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| DE1257584T1 (de) * | 2000-02-24 | 2003-05-28 | Lilly Co Eli | Humanisierte antikörper, die amyloid beta peptid demarkieren |
| PE20020574A1 (es) * | 2000-12-06 | 2002-07-02 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido amiloideo beta |
| AR038568A1 (es) * | 2002-02-20 | 2005-01-19 | Hoffmann La Roche | Anticuerpos anti-a beta y su uso |
| WO2005018424A2 (en) * | 2003-08-18 | 2005-03-03 | Research Foundation For Mental Hygiene, Inc. | Antibodies specific for fibrillar amyloid and a procedure to detect fibrillar amyloid deposits |
| TW200635608A (en) * | 2004-12-15 | 2006-10-16 | Neuralab Ltd | Aβ antibodies for use in improving cognition |
| CN101111264A (zh) * | 2005-01-28 | 2008-01-23 | 惠氏公司 | 稳定化的液体多肽制剂 |
| SG10201404801YA (en) * | 2005-12-12 | 2014-09-26 | Ac Immune Sa | Monoclonal antibody |
| WO2009033743A1 (en) * | 2007-09-13 | 2009-03-19 | University Of Zurich Prorektorat Forschung | Monoclonal amyloid beta (abeta)-specific antibody and uses thereof |
| WO2011133919A1 (en) * | 2010-04-22 | 2011-10-27 | Janssen Alzheimer Immunotherapy | Use of tau to monitor immunotherapy |
| US20130084245A1 (en) * | 2010-02-25 | 2013-04-04 | Wyeth Llc | Pet monitoring of a-beta-directed immunotherapy |
-
2013
- 2013-06-18 KR KR20157001775A patent/KR20150036163A/ko not_active Withdrawn
- 2013-06-18 CN CN201380035339.9A patent/CN105579061A/zh active Pending
- 2013-06-18 RU RU2014153675A patent/RU2014153675A/ru not_active Application Discontinuation
- 2013-06-18 HK HK15109545.4A patent/HK1208810A1/xx unknown
- 2013-06-18 MX MX2014015744A patent/MX2014015744A/es unknown
- 2013-06-18 AU AU2013287119A patent/AU2013287119A1/en not_active Abandoned
- 2013-06-18 JP JP2015520289A patent/JP2015526409A/ja not_active Abandoned
- 2013-06-18 EP EP13812620.6A patent/EP2869846A4/en not_active Withdrawn
- 2013-06-18 WO PCT/US2013/046399 patent/WO2014007982A2/en not_active Ceased
- 2013-06-18 CA CA2877516A patent/CA2877516A1/en not_active Abandoned
- 2013-06-18 US US14/410,018 patent/US20150353631A1/en not_active Abandoned
- 2013-06-18 BR BR112014033066A patent/BR112014033066A2/pt active Search and Examination
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2015
- 2015-01-01 IL IL236549A patent/IL236549A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN105579061A (zh) | 2016-05-11 |
| AU2013287119A1 (en) | 2015-01-22 |
| EP2869846A4 (en) | 2016-01-13 |
| IL236549A0 (en) | 2015-02-26 |
| CA2877516A1 (en) | 2014-01-03 |
| KR20150036163A (ko) | 2015-04-07 |
| RU2014153675A (ru) | 2016-08-27 |
| BR112014033066A2 (pt) | 2017-08-01 |
| EP2869846A2 (en) | 2015-05-13 |
| US20150353631A1 (en) | 2015-12-10 |
| WO2014007982A2 (en) | 2014-01-09 |
| WO2014007982A3 (en) | 2014-04-03 |
| JP2015526409A (ja) | 2015-09-10 |
| HK1208810A1 (en) | 2016-03-18 |
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