MX2014013452A - Combinaciones farmaceuticas para el tratamiento de trastornos metabolicos. - Google Patents
Combinaciones farmaceuticas para el tratamiento de trastornos metabolicos.Info
- Publication number
- MX2014013452A MX2014013452A MX2014013452A MX2014013452A MX2014013452A MX 2014013452 A MX2014013452 A MX 2014013452A MX 2014013452 A MX2014013452 A MX 2014013452A MX 2014013452 A MX2014013452 A MX 2014013452A MX 2014013452 A MX2014013452 A MX 2014013452A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- metabolic disorders
- pharmaceutical combinations
- diabetes mellitus
- type
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
La invención se refiere a una composición farmacéutica que comprende el compuesto de fórmula I o solvatos, hidratos o sales aceptables para uso farmacéutico del mismo en combinación con al menos un segundo agente terapéutico 2 que es apropiado en el tratamiento o prevención de una o más afecciones seleccionadas de diabetes mellitus tipo 1, diabetes mellitus tipo 2, tolerancia deteriorada a la glucosa y hiperglicemia. Además, la presente invención se refiere a métodos para prevenir o tratar trastornos metabólicos y afecciones afines.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261644721P | 2012-05-09 | 2012-05-09 | |
US201261645787P | 2012-05-11 | 2012-05-11 | |
PCT/EP2013/059423 WO2013167554A1 (en) | 2012-05-09 | 2013-05-07 | Pharmaceutical combinations for the treatment of metabolic disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2014013452A true MX2014013452A (es) | 2014-12-08 |
Family
ID=48485118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014013452A MX2014013452A (es) | 2012-05-09 | 2013-05-07 | Combinaciones farmaceuticas para el tratamiento de trastornos metabolicos. |
Country Status (18)
Country | Link |
---|---|
US (3) | US20130303446A1 (es) |
EP (1) | EP2846797A1 (es) |
JP (1) | JP2015516404A (es) |
KR (1) | KR20150014488A (es) |
CN (1) | CN104427985A (es) |
AR (1) | AR090999A1 (es) |
AU (1) | AU2013258109A1 (es) |
BR (1) | BR112014027884A2 (es) |
CA (1) | CA2872932A1 (es) |
CL (1) | CL2014002978A1 (es) |
EA (1) | EA201401231A1 (es) |
IL (1) | IL235058A0 (es) |
IN (1) | IN2014DN08582A (es) |
MX (1) | MX2014013452A (es) |
PH (1) | PH12014502448A1 (es) |
TW (1) | TW201406374A (es) |
UY (1) | UY34800A (es) |
WO (1) | WO2013167554A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10383580B2 (en) * | 2012-12-31 | 2019-08-20 | Abbott Diabetes Care Inc. | Analysis of glucose median, variability, and hypoglycemia risk for therapy guidance |
WO2015101916A1 (en) | 2013-12-30 | 2015-07-09 | Mylan Laboratories Ltd. | Process for the preparation of empagliflozin |
EP3207928B1 (en) * | 2014-10-17 | 2021-03-10 | Hyundai Pharm Co., Ltd. | Composite preparation, containing novel 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative and another active ingredient, for preventing or treating metabolic diseases |
CN109195595A (zh) * | 2016-06-02 | 2019-01-11 | 塞多麦克斯有限公司 | 使用α,α-取代的长链两亲性羧酸盐的糖尿病治疗方案 |
RU2740902C2 (ru) * | 2016-06-03 | 2021-01-21 | Хемоцентрикс, Инк. | Способ лечения фиброза печени |
JP6861795B2 (ja) * | 2016-08-12 | 2021-04-21 | ノブメタファーマ カンパニー リミテッド | アモジアキンおよび抗糖尿薬物を有効成分として含有する糖尿病の予防または治療用薬学的組成物 |
NL2019605B1 (en) * | 2017-09-22 | 2019-03-28 | Cfm Pharma Holding B V | Vanadyl and vanadate for use in reducing stress-induced metabolic derangement |
CN110652498B (zh) * | 2019-11-22 | 2022-04-05 | 河南合智医药科技有限公司 | 一种用于治疗2型糖尿病的药物制剂及其制备方法 |
CN112220768A (zh) * | 2020-10-15 | 2021-01-15 | 四川维奥制药有限公司 | 一种米格列醇片剂的制备方法 |
WO2024055932A1 (zh) * | 2022-09-13 | 2024-03-21 | 亚宝药业集团股份有限公司 | 氮杂环化合物、其药物组合物和用于预防和/或治疗疾病的用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2796940B1 (fr) * | 1999-07-26 | 2005-04-08 | Lipha | Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant |
ES2387881T3 (es) | 2004-03-16 | 2012-10-03 | Boehringer Ingelheim International Gmbh | Derivados de benceno sustituidos por glucopiranosilo, medicamentos que contienen estos compuestos, su uso y procedimiento para su preparación |
DE602005009745D1 (de) | 2004-12-16 | 2008-10-23 | Boehringer Ingelheim Pharma | Glucopyranosyl-substituierte benzen-derivate, medikamente mit solchen verbindungen, ihre verwendung und herstellungsverfahren dafür |
US7723309B2 (en) | 2005-05-03 | 2010-05-25 | Boehringer Ingelheim International Gmbh | Crystalline forms of 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((R)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a method for its preparation and the use thereof for preparing medicaments |
UA91546C2 (uk) | 2005-05-03 | 2010-08-10 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ |
US7772191B2 (en) | 2005-05-10 | 2010-08-10 | Boehringer Ingelheim International Gmbh | Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein |
AR056195A1 (es) | 2005-09-15 | 2007-09-26 | Boehringer Ingelheim Int | Procedimientos para preparar derivados de (etinil-bencil)-benceno sustituidos de glucopiranosilo y compuestos intermedios de los mismos |
KR20080102395A (ko) | 2006-02-15 | 2008-11-25 | 베링거 인겔하임 인터내셔날 게엠베하 | 글루코피라노실-치환된 벤조니트릴 유도체, 당해 화합물을 함유하는 약제학적 조성물, 이들의 용도 및 이들의 제조방법 |
EP2054426A1 (en) | 2006-08-15 | 2009-05-06 | Boehringer Ingelheim International GmbH | Glucopyranosyl-substituted cyclopropylbenzene derivatives, pharmaceutical compositions containing such compounds, their use as sglt inhibitors and process for their manufacture |
US7879806B2 (en) | 2006-11-06 | 2011-02-01 | Boehringer Ingelheim International Gmbh | Glucopyranosyl-substituted benzyl-benzonitrile derivates, medicaments containing such compounds, their use and process for their manufacture |
UY33001A (es) | 2009-11-06 | 2011-05-31 | Boehringer Ingelheim Int | Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina |
TWI537258B (zh) * | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基-及雜環芳基羰基衍生物 |
-
2013
- 2013-05-07 AU AU2013258109A patent/AU2013258109A1/en not_active Abandoned
- 2013-05-07 IN IN8582DEN2014 patent/IN2014DN08582A/en unknown
- 2013-05-07 CA CA2872932A patent/CA2872932A1/en not_active Abandoned
- 2013-05-07 WO PCT/EP2013/059423 patent/WO2013167554A1/en active Application Filing
- 2013-05-07 US US13/888,602 patent/US20130303446A1/en not_active Abandoned
- 2013-05-07 KR KR1020147034475A patent/KR20150014488A/ko not_active Application Discontinuation
- 2013-05-07 BR BR112014027884A patent/BR112014027884A2/pt not_active IP Right Cessation
- 2013-05-07 EA EA201401231A patent/EA201401231A1/ru unknown
- 2013-05-07 EP EP13724752.4A patent/EP2846797A1/en not_active Withdrawn
- 2013-05-07 MX MX2014013452A patent/MX2014013452A/es unknown
- 2013-05-07 CN CN201380023728.XA patent/CN104427985A/zh active Pending
- 2013-05-07 JP JP2015510776A patent/JP2015516404A/ja active Pending
- 2013-05-08 TW TW102116415A patent/TW201406374A/zh unknown
- 2013-05-08 AR ARP130101606A patent/AR090999A1/es unknown
- 2013-05-09 UY UY0001034800A patent/UY34800A/es unknown
-
2014
- 2014-09-05 US US14/478,368 patent/US20140378398A1/en not_active Abandoned
- 2014-10-07 IL IL235058A patent/IL235058A0/en unknown
- 2014-11-03 CL CL2014002978A patent/CL2014002978A1/es unknown
- 2014-11-03 PH PH12014502448A patent/PH12014502448A1/en unknown
-
2015
- 2015-11-18 US US14/944,249 patent/US20160067227A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
UY34800A (es) | 2013-11-29 |
KR20150014488A (ko) | 2015-02-06 |
US20130303446A1 (en) | 2013-11-14 |
AR090999A1 (es) | 2014-12-30 |
CN104427985A (zh) | 2015-03-18 |
IL235058A0 (en) | 2014-12-31 |
AU2013258109A1 (en) | 2014-10-30 |
US20160067227A1 (en) | 2016-03-10 |
IN2014DN08582A (es) | 2015-05-22 |
PH12014502448A1 (en) | 2015-01-12 |
JP2015516404A (ja) | 2015-06-11 |
EP2846797A1 (en) | 2015-03-18 |
US20140378398A1 (en) | 2014-12-25 |
CA2872932A1 (en) | 2013-11-14 |
WO2013167554A1 (en) | 2013-11-14 |
CL2014002978A1 (es) | 2015-03-13 |
TW201406374A (zh) | 2014-02-16 |
EA201401231A1 (ru) | 2015-08-31 |
BR112014027884A2 (pt) | 2017-06-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PH12014502448A1 (en) | Pharmaceutical combinations for the treatment of metabolic disorders | |
PH12018500767A1 (en) | Pharmaceutical composition, methods for treating and uses thereof | |
MX2013004699A (es) | Combinaciones farmaceuticas para el tratamiento de trastornos metabolicos. | |
MY174002A (en) | Combination theraphy for the treatment of diabetes | |
TN2011000437A1 (en) | Substituted azoanthracene derivatives, pharmaceutical compositions, and methods of use thereof | |
WO2011127333A3 (en) | Compounds for treating disease, for administering, and for pharmaceutical compositions | |
WO2010029089A3 (en) | Combination therapy for the treatment of diabetes and related conditions | |
IN2012DN01233A (es) | ||
UA102429C2 (ru) | Фармацевтическая композиция, которая включает ингибитор sglt-2, ингибитор дпп-iv и другой антидиабетический агент, и ее применение | |
WO2015157559A3 (en) | 10',11'-modified saxitoxins useful for the treatment of pain | |
EA201391486A1 (ru) | Способы и композиции для лечения болезни паркинсона | |
MX2013003034A (es) | Lactamas piperidinilo-substituidas como moduladores de gpr119. | |
PH12014502567A1 (en) | Piperidine derivatives for gpr119 agonist | |
MX2012006734A (es) | Tiazolidinadionas moderadoras de receptores activados por proliferador de peroxisoma (ppar) y combinaciones para el tratamiento de obesidad y otras enfermedades metabolicas. | |
EA201070477A1 (ru) | Транс-кломифен для лечения метаболического синдрома | |
BR112013026257A2 (pt) | derivados de glicosídeo e usos dos mesmos para o tratamento de diabetes | |
PH12015500860A1 (en) | 2-phenyl -5- heterocyclyl -tetrahydro-2h- pyran-3-amine compounds for use in the treatment of diabetes and its associated disorders | |
WO2018005794A3 (en) | Novel non-systemic tgr5 agonists | |
MX2013002208A (es) | Derivados de sulfonilpiperazina que interactuan con la proteina reguladora de glucocinasa para el tratamiento de diabetes. | |
MY156174A (en) | 4-(1,2,4-dioxazol-3-yl)benzamides for the treatment of diabetes and obesity | |
MX2012006287A (es) | Activadores de azaindol glucocinasa. | |
JO2820B1 (en) | Combination of refined thiazolium salt or a primary compound and artemisinin or a derivative thereof to treat serious malaria cases | |
AU2016219606A1 (en) | Pharmaceutical composition for treating or preventing burn injuries | |
PH12016500980A1 (en) | Amide derivatives for gpr119 agonist | |
MX2013011561A (es) | Compuestos de benzodioxepina y benzodioxina que interactuan con la proteina reguladora de glucocinasa para el tratamiento de diabetes. |