MX2014009688A - Composicion farmaceutica en emulgel de invermectina para uso veterinario como sistema promotor y bioadhesivo en el tratamiento antiparasitario, y metodo para obtener la misma. - Google Patents

Composicion farmaceutica en emulgel de invermectina para uso veterinario como sistema promotor y bioadhesivo en el tratamiento antiparasitario, y metodo para obtener la misma.

Info

Publication number
MX2014009688A
MX2014009688A MX2014009688A MX2014009688A MX2014009688A MX 2014009688 A MX2014009688 A MX 2014009688A MX 2014009688 A MX2014009688 A MX 2014009688A MX 2014009688 A MX2014009688 A MX 2014009688A MX 2014009688 A MX2014009688 A MX 2014009688A
Authority
MX
Mexico
Prior art keywords
agent
bio
pharmaceutical composition
oil
active ingredient
Prior art date
Application number
MX2014009688A
Other languages
English (en)
Other versions
MX359970B (es
Inventor
David Quintanar Guerrero
Juan Pablo Martínez Labat
Susana Elisa Mendoza Elvira
Gustavo Vidal Romero
Victor Andrés Trenado Hernández
Original Assignee
Univ Nac Autónoma De México
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nac Autónoma De México filed Critical Univ Nac Autónoma De México
Priority to MX2014009688A priority Critical patent/MX359970B/es
Priority to PCT/MX2015/000114 priority patent/WO2016024855A1/es
Priority to US15/503,033 priority patent/US20170232026A1/en
Publication of MX2014009688A publication Critical patent/MX2014009688A/es
Publication of MX359970B publication Critical patent/MX359970B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a una composición farmacéutica que comprende: al menos un principio activo antiparasitario que es el encargado de proveer el efecto terapéutico farmacológico; un agente con propiedades bio-adhesivas que ayuda a reducir la motilidad y reproducción de los parásitos infestantes, aumentando la estancia del producto sobre la piel de los animales; un agente con propiedades promotoras de permeación o absorción que coadyuva a incrementar la permeabilidad cutánea del principio activo; un agente surfactante o tensoactivo, el cual es adsorbido en una interfase aceite-agua, y como consecuencia de ello, las moléculas de dicho agente tensoactivo forman una especie de "puente" entre la fase polar (agua) y la fase no polar (aceite), haciendo así que la transición entre ambas fases sea menos brusca; un aceite que va a formar la fase oleosa de la emulsión y es quien va a incorporar al principio activo; y, un agente neutralizante.
MX2014009688A 2014-08-12 2014-08-12 Composición farmacéutica en emulgel de invermectina para uso veterinario como sistema promotor y bioadhesivo en el tratamiento antiparasitario, y método para obtener la misma. MX359970B (es)

Priority Applications (3)

Application Number Priority Date Filing Date Title
MX2014009688A MX359970B (es) 2014-08-12 2014-08-12 Composición farmacéutica en emulgel de invermectina para uso veterinario como sistema promotor y bioadhesivo en el tratamiento antiparasitario, y método para obtener la misma.
PCT/MX2015/000114 WO2016024855A1 (es) 2014-08-12 2015-08-12 Composición farmaceutica en emulgel de ivermectina para uso veterinario como sistema promotor y bioadhesivo en el tratamiento antiparasitario, y metodo para obtener la misma
US15/503,033 US20170232026A1 (en) 2014-08-12 2015-08-12 Pharmaceutical composition in ivermectin emulgel for veterinary use as a promoter system and bio-adhesive in antiparasitic treatment, and method for the production thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2014009688A MX359970B (es) 2014-08-12 2014-08-12 Composición farmacéutica en emulgel de invermectina para uso veterinario como sistema promotor y bioadhesivo en el tratamiento antiparasitario, y método para obtener la misma.

Publications (2)

Publication Number Publication Date
MX2014009688A true MX2014009688A (es) 2016-02-12
MX359970B MX359970B (es) 2018-10-05

Family

ID=55304397

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014009688A MX359970B (es) 2014-08-12 2014-08-12 Composición farmacéutica en emulgel de invermectina para uso veterinario como sistema promotor y bioadhesivo en el tratamiento antiparasitario, y método para obtener la misma.

Country Status (3)

Country Link
US (1) US20170232026A1 (es)
MX (1) MX359970B (es)
WO (1) WO2016024855A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3326609A1 (en) 2016-11-24 2018-05-30 Nestlé Skin Health SA Composition comprising avermectin compounds without gelling agents
EP3326608A1 (en) 2016-11-24 2018-05-30 Nestlé Skin Health SA Composition comprising avermectin compounds without solid fatty substances
EP3326614A1 (en) * 2016-11-24 2018-05-30 Nestlé Skin Health SA Composition comprising avermectin compounds without solvents and propenetrating agents of avermectin compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2753377B1 (fr) * 1996-09-19 1999-09-24 Rhone Merieux Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides
DE19654079A1 (de) * 1996-12-23 1998-06-25 Bayer Ag Endo-ekto-parasitizide Mittel
JP2006508957A (ja) * 2002-11-14 2006-03-16 ノバルティス アクチエンゲゼルシャフト 害虫を防除するための組合せ生成物
CL2008001614A1 (es) * 2007-06-05 2008-08-08 Wyeth Corp Composicion parasiticida veterinaria que comprende un disolvente que no contiene hidroxilo, un estabilizador, amitraz y opcionalmente una lactona macrociclica y miristato de isopropilo; y su uso para tratar o controlar una infestacion o infeccion par
GB201021836D0 (en) * 2010-12-21 2011-02-02 Norbrook Lab Ltd Topical Composition

Also Published As

Publication number Publication date
MX359970B (es) 2018-10-05
WO2016024855A1 (es) 2016-02-18
US20170232026A1 (en) 2017-08-17

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