BR112018001435A2 - métodos para entrega linfática de agentes ativos - Google Patents
métodos para entrega linfática de agentes ativosInfo
- Publication number
- BR112018001435A2 BR112018001435A2 BR112018001435A BR112018001435A BR112018001435A2 BR 112018001435 A2 BR112018001435 A2 BR 112018001435A2 BR 112018001435 A BR112018001435 A BR 112018001435A BR 112018001435 A BR112018001435 A BR 112018001435A BR 112018001435 A2 BR112018001435 A2 BR 112018001435A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- active agents
- lymphatic delivery
- delivery
- agents
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title 1
- 230000001926 lymphatic effect Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 239000012867 bioactive agent Substances 0.000 abstract 1
- 210000002615 epidermis Anatomy 0.000 abstract 1
- 210000004324 lymphatic system Anatomy 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Cosmetics (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
a presente invenção diz respeito à entrega de agentes à pele. os métodos para fornecer agentes, tais como agentes bioativos, são contemplados pela presente invenção. especificamente, são descritos métodos para entregar um agente a uma ou mais áreas da epiderme e, assim, ao sistema linfático.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562196568P | 2015-07-24 | 2015-07-24 | |
US201562196558P | 2015-07-24 | 2015-07-24 | |
PCT/US2016/043656 WO2017019535A2 (en) | 2015-07-24 | 2016-07-22 | Methods for lymphatic delivery of active agents |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112018001435A2 true BR112018001435A2 (pt) | 2018-09-11 |
Family
ID=57885089
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018001435A BR112018001435A2 (pt) | 2015-07-24 | 2016-07-22 | métodos para entrega linfática de agentes ativos |
Country Status (15)
Country | Link |
---|---|
US (3) | US10737082B2 (pt) |
EP (2) | EP3922238A1 (pt) |
JP (3) | JP6929829B2 (pt) |
KR (1) | KR20180035210A (pt) |
CN (1) | CN107949418B (pt) |
AU (3) | AU2016297832B2 (pt) |
BR (1) | BR112018001435A2 (pt) |
CA (1) | CA2991459A1 (pt) |
DK (1) | DK3325081T3 (pt) |
ES (1) | ES2893673T3 (pt) |
HU (1) | HUE056424T2 (pt) |
MX (2) | MX2018000126A (pt) |
PL (1) | PL3325081T3 (pt) |
RU (1) | RU2719946C2 (pt) |
WO (1) | WO2017019535A2 (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK3325081T3 (da) * | 2015-07-24 | 2021-10-11 | Sorrento Therapeutics Inc | Fremgangsmåder til lymfatisk levering af aktive stoffer |
EP3325080B1 (en) * | 2015-07-24 | 2021-09-01 | Sorrento Therapeutics, Inc. | Methods for better delivery of active agents to tumors |
US20200206352A1 (en) * | 2017-08-31 | 2020-07-02 | Tohoku University | Optimal osmotic range for a drug-containing solution suitable for lymphatic delivery |
CN115038463A (zh) | 2019-12-05 | 2022-09-09 | 索伦托药业有限公司 | 通过淋巴递送装置施用抗pd-1或抗pd-l1治疗剂以治疗癌症的方法 |
JP7509402B2 (ja) | 2020-02-26 | 2024-07-02 | 国立大学法人 和歌山大学 | 解析装置、センシングシステム、解析装置の動作方法、及び、コンピュータプログラム |
JP2024505198A (ja) | 2021-01-22 | 2024-02-05 | ソレント・セラピューティクス・インコーポレイテッド | コロナウイルスワクチンのマイクロリットルスケールのリンパ送達のためのデバイス |
WO2022192594A2 (en) | 2021-03-11 | 2022-09-15 | Sorrento Therapeutics, Inc. | Nucleic acid molecules and vaccines comprising same for the prevention and treatment of coronavirus infections and disease |
EP4352100A1 (en) | 2021-06-09 | 2024-04-17 | Sorrento Therapeutics, Inc. | Method of treating cancer by administration of an anti-pd-1 or anti-pd-l1 therapeutic agent via a lymphatic microneedle delivery device |
CN113368385A (zh) * | 2021-06-21 | 2021-09-10 | 温州医科大学慈溪生物医药研究院 | 利用淋巴通路递送生物大分子药物入脑的输送系统 |
CA3228858A1 (en) | 2021-08-18 | 2023-02-23 | Russell F. Ross | Therapeutic agents targeting the lymphatic system |
Family Cites Families (30)
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IE72524B1 (en) | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
US6503231B1 (en) * | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
US20020095134A1 (en) * | 1999-10-14 | 2002-07-18 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
CN1400897A (zh) * | 2000-06-01 | 2003-03-05 | 沃特森药物公司 | Lasofoxifene的经皮转运 |
MXPA04002283A (es) * | 2001-09-12 | 2004-06-29 | Becton Dickinson Co | Dispositivo de pluma a base de microaguja para el suministro de farmaco y metodo para utilizar el mismo. |
EP1583423A4 (en) * | 2003-01-16 | 2006-05-10 | Becton Dickinson Co | INTRADERMAL DISTRIBUTION OF CELLS USING THIN MICROCANULA |
BRPI0411428A (pt) * | 2003-06-13 | 2006-07-25 | Becton Dickinson Co | distribuição intradérmica de agentes biologicamente ativos |
CA2536669A1 (en) | 2003-08-26 | 2005-03-17 | Becton, Dickinson And Company | Methods for intradermal delivery of therapeutics agents |
US20070088414A1 (en) * | 2005-05-25 | 2007-04-19 | Campbell Robert L | Particulate formulations for intradermal delivery of biologically active agents |
WO2007019678A1 (en) | 2005-08-12 | 2007-02-22 | University Health Network | Methods and devices for lymphatic targeting |
US20070087029A1 (en) | 2005-10-14 | 2007-04-19 | Pakala Syamasundar V | Localized delivery to the lymphatic system |
US8197435B2 (en) * | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
WO2008038140A2 (en) * | 2006-06-07 | 2008-04-03 | Foamix Ltd. | Foamable vehicle comprising polypropylene glycol alkyl ether and pharmaceutical compositions thereof |
EP2100850A1 (en) * | 2008-03-11 | 2009-09-16 | Stichting Voor De Technische Wetenschappen | Microneedle array and a method for manufacturing microneedles |
US20110150765A1 (en) * | 2008-10-31 | 2011-06-23 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Frozen compositions and methods for piercing a substrate |
US9586044B2 (en) * | 2010-04-28 | 2017-03-07 | Kimberly-Clark Worldwide, Inc. | Method for increasing the permeability of an epithelial barrier |
PT2563450T (pt) * | 2010-04-28 | 2017-08-28 | Kimberly Clark Co | Dispositivo para entrega de medicação para a artrite reumatóide |
CN102985131B (zh) | 2010-04-28 | 2016-06-29 | 金伯利-克拉克环球有限公司 | 用于递送siRNA的医疗装置 |
JP5860453B2 (ja) | 2010-04-28 | 2016-02-16 | キンバリー クラーク ワールドワイド インコーポレイテッド | 表面にナノ構造体を含む複合マイクロニードルアレイ |
US20120187814A1 (en) | 2011-01-25 | 2012-07-26 | Fryling Nicholas A | Furniture System and a Frame Assembly for a Furniture System |
US20120245445A1 (en) * | 2011-03-21 | 2012-09-27 | Michael Darryl Black | Glucose Monitoring System |
PT2768942T (pt) * | 2011-10-17 | 2020-01-21 | Massachusetts Inst Technology | Entrega intracelular |
US20170246439A9 (en) * | 2011-10-27 | 2017-08-31 | Kimberly-Clark Worldwide, Inc. | Increased Bioavailability of Transdermally Delivered Agents |
EP3574950B1 (en) * | 2011-10-27 | 2021-02-17 | Sorrento Therapeutics, Inc. | Transdermal delivery of high viscosity bioactive agents |
EP4112112A1 (en) * | 2012-05-01 | 2023-01-04 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Tip-loaded microneedle arrays for transdermal insertion |
CN105073179B (zh) | 2013-02-28 | 2019-03-19 | 索伦托治疗有限公司 | 经皮药物递送装置 |
EP2961469A4 (en) | 2013-02-28 | 2016-10-26 | Kimberly Clark Co | DEVICE FOR DELIVERY OF MEDICAMENT |
JP2016517762A (ja) | 2013-05-23 | 2016-06-20 | キンバリー クラーク ワールドワイド インコーポレイテッド | 開放チャネル断面形状が改善されたマイクロニードル |
EP3325080B1 (en) * | 2015-07-24 | 2021-09-01 | Sorrento Therapeutics, Inc. | Methods for better delivery of active agents to tumors |
DK3325081T3 (da) * | 2015-07-24 | 2021-10-11 | Sorrento Therapeutics Inc | Fremgangsmåder til lymfatisk levering af aktive stoffer |
-
2016
- 2016-07-22 DK DK16831144.7T patent/DK3325081T3/da active
- 2016-07-22 BR BR112018001435A patent/BR112018001435A2/pt not_active Application Discontinuation
- 2016-07-22 AU AU2016297832A patent/AU2016297832B2/en active Active
- 2016-07-22 JP JP2018500418A patent/JP6929829B2/ja active Active
- 2016-07-22 CN CN201680050966.3A patent/CN107949418B/zh active Active
- 2016-07-22 ES ES16831144T patent/ES2893673T3/es active Active
- 2016-07-22 CA CA2991459A patent/CA2991459A1/en active Pending
- 2016-07-22 MX MX2018000126A patent/MX2018000126A/es unknown
- 2016-07-22 RU RU2018104104A patent/RU2719946C2/ru active
- 2016-07-22 US US15/744,385 patent/US10737082B2/en active Active
- 2016-07-22 EP EP21189701.2A patent/EP3922238A1/en active Pending
- 2016-07-22 EP EP16831144.7A patent/EP3325081B1/en active Active
- 2016-07-22 WO PCT/US2016/043656 patent/WO2017019535A2/en active Application Filing
- 2016-07-22 HU HUE16831144A patent/HUE056424T2/hu unknown
- 2016-07-22 PL PL16831144T patent/PL3325081T3/pl unknown
- 2016-07-22 KR KR1020187003327A patent/KR20180035210A/ko not_active Application Discontinuation
-
2018
- 2018-01-08 MX MX2022014634A patent/MX2022014634A/es unknown
-
2020
- 2020-07-10 US US16/925,548 patent/US20200338329A1/en not_active Abandoned
- 2020-09-18 AU AU2020233748A patent/AU2020233748B2/en active Active
-
2021
- 2021-08-11 JP JP2021131298A patent/JP7167272B2/ja active Active
-
2022
- 2022-10-26 JP JP2022171479A patent/JP2023015135A/ja not_active Withdrawn
- 2022-11-21 AU AU2022275393A patent/AU2022275393A1/en active Pending
-
2024
- 2024-02-15 US US18/442,568 patent/US20240181235A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
MX2022014634A (es) | 2023-01-18 |
DK3325081T3 (da) | 2021-10-11 |
US20200338329A1 (en) | 2020-10-29 |
AU2020233748A1 (en) | 2020-10-08 |
PL3325081T3 (pl) | 2021-12-20 |
CN107949418B (zh) | 2024-07-02 |
JP2021185160A (ja) | 2021-12-09 |
AU2016297832B2 (en) | 2020-07-16 |
JP2023015135A (ja) | 2023-01-31 |
AU2016297832A1 (en) | 2018-02-15 |
CN107949418A (zh) | 2018-04-20 |
JP7167272B2 (ja) | 2022-11-08 |
US20180193625A1 (en) | 2018-07-12 |
RU2018104104A3 (pt) | 2019-10-31 |
WO2017019535A2 (en) | 2017-02-02 |
US20240181235A1 (en) | 2024-06-06 |
EP3325081A4 (en) | 2019-04-10 |
AU2022275393A1 (en) | 2023-01-05 |
EP3922238A1 (en) | 2021-12-15 |
EP3325081B1 (en) | 2021-09-08 |
KR20180035210A (ko) | 2018-04-05 |
JP6929829B2 (ja) | 2021-09-01 |
MX2018000126A (es) | 2018-03-23 |
RU2719946C2 (ru) | 2020-04-23 |
JP2018522002A (ja) | 2018-08-09 |
AU2020233748B2 (en) | 2022-08-25 |
HUE056424T2 (hu) | 2022-02-28 |
US10737082B2 (en) | 2020-08-11 |
ES2893673T3 (es) | 2022-02-09 |
CA2991459A1 (en) | 2017-02-02 |
EP3325081A2 (en) | 2018-05-30 |
RU2018104104A (ru) | 2019-08-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Owner name: SORRENTO THERAPEUTICS, INC. (US) |
|
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |