BR112018001435A2 - métodos para entrega linfática de agentes ativos - Google Patents

métodos para entrega linfática de agentes ativos

Info

Publication number
BR112018001435A2
BR112018001435A2 BR112018001435A BR112018001435A BR112018001435A2 BR 112018001435 A2 BR112018001435 A2 BR 112018001435A2 BR 112018001435 A BR112018001435 A BR 112018001435A BR 112018001435 A BR112018001435 A BR 112018001435A BR 112018001435 A2 BR112018001435 A2 BR 112018001435A2
Authority
BR
Brazil
Prior art keywords
methods
active agents
lymphatic delivery
delivery
agents
Prior art date
Application number
BR112018001435A
Other languages
English (en)
Inventor
Frederick Ross Russell
Original Assignee
Kimberly Clark Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kimberly Clark Co filed Critical Kimberly Clark Co
Publication of BR112018001435A2 publication Critical patent/BR112018001435A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

a presente invenção diz respeito à entrega de agentes à pele. os métodos para fornecer agentes, tais como agentes bioativos, são contemplados pela presente invenção. especificamente, são descritos métodos para entregar um agente a uma ou mais áreas da epiderme e, assim, ao sistema linfático.
BR112018001435A 2015-07-24 2016-07-22 métodos para entrega linfática de agentes ativos BR112018001435A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562196568P 2015-07-24 2015-07-24
US201562196558P 2015-07-24 2015-07-24
PCT/US2016/043656 WO2017019535A2 (en) 2015-07-24 2016-07-22 Methods for lymphatic delivery of active agents

Publications (1)

Publication Number Publication Date
BR112018001435A2 true BR112018001435A2 (pt) 2018-09-11

Family

ID=57885089

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018001435A BR112018001435A2 (pt) 2015-07-24 2016-07-22 métodos para entrega linfática de agentes ativos

Country Status (15)

Country Link
US (3) US10737082B2 (pt)
EP (2) EP3922238A1 (pt)
JP (3) JP6929829B2 (pt)
KR (1) KR20180035210A (pt)
CN (1) CN107949418B (pt)
AU (3) AU2016297832B2 (pt)
BR (1) BR112018001435A2 (pt)
CA (1) CA2991459A1 (pt)
DK (1) DK3325081T3 (pt)
ES (1) ES2893673T3 (pt)
HU (1) HUE056424T2 (pt)
MX (2) MX2018000126A (pt)
PL (1) PL3325081T3 (pt)
RU (1) RU2719946C2 (pt)
WO (1) WO2017019535A2 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3325081T3 (da) * 2015-07-24 2021-10-11 Sorrento Therapeutics Inc Fremgangsmåder til lymfatisk levering af aktive stoffer
EP3325080B1 (en) * 2015-07-24 2021-09-01 Sorrento Therapeutics, Inc. Methods for better delivery of active agents to tumors
US20200206352A1 (en) * 2017-08-31 2020-07-02 Tohoku University Optimal osmotic range for a drug-containing solution suitable for lymphatic delivery
CN115038463A (zh) 2019-12-05 2022-09-09 索伦托药业有限公司 通过淋巴递送装置施用抗pd-1或抗pd-l1治疗剂以治疗癌症的方法
JP7509402B2 (ja) 2020-02-26 2024-07-02 国立大学法人 和歌山大学 解析装置、センシングシステム、解析装置の動作方法、及び、コンピュータプログラム
JP2024505198A (ja) 2021-01-22 2024-02-05 ソレント・セラピューティクス・インコーポレイテッド コロナウイルスワクチンのマイクロリットルスケールのリンパ送達のためのデバイス
WO2022192594A2 (en) 2021-03-11 2022-09-15 Sorrento Therapeutics, Inc. Nucleic acid molecules and vaccines comprising same for the prevention and treatment of coronavirus infections and disease
EP4352100A1 (en) 2021-06-09 2024-04-17 Sorrento Therapeutics, Inc. Method of treating cancer by administration of an anti-pd-1 or anti-pd-l1 therapeutic agent via a lymphatic microneedle delivery device
CN113368385A (zh) * 2021-06-21 2021-09-10 温州医科大学慈溪生物医药研究院 利用淋巴通路递送生物大分子药物入脑的输送系统
CA3228858A1 (en) 2021-08-18 2023-02-23 Russell F. Ross Therapeutic agents targeting the lymphatic system

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE72524B1 (en) 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US6503231B1 (en) * 1998-06-10 2003-01-07 Georgia Tech Research Corporation Microneedle device for transport of molecules across tissue
US20020095134A1 (en) * 1999-10-14 2002-07-18 Pettis Ronald J. Method for altering drug pharmacokinetics based on medical delivery platform
CN1400897A (zh) * 2000-06-01 2003-03-05 沃特森药物公司 Lasofoxifene的经皮转运
MXPA04002283A (es) * 2001-09-12 2004-06-29 Becton Dickinson Co Dispositivo de pluma a base de microaguja para el suministro de farmaco y metodo para utilizar el mismo.
EP1583423A4 (en) * 2003-01-16 2006-05-10 Becton Dickinson Co INTRADERMAL DISTRIBUTION OF CELLS USING THIN MICROCANULA
BRPI0411428A (pt) * 2003-06-13 2006-07-25 Becton Dickinson Co distribuição intradérmica de agentes biologicamente ativos
CA2536669A1 (en) 2003-08-26 2005-03-17 Becton, Dickinson And Company Methods for intradermal delivery of therapeutics agents
US20070088414A1 (en) * 2005-05-25 2007-04-19 Campbell Robert L Particulate formulations for intradermal delivery of biologically active agents
WO2007019678A1 (en) 2005-08-12 2007-02-22 University Health Network Methods and devices for lymphatic targeting
US20070087029A1 (en) 2005-10-14 2007-04-19 Pakala Syamasundar V Localized delivery to the lymphatic system
US8197435B2 (en) * 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
WO2008038140A2 (en) * 2006-06-07 2008-04-03 Foamix Ltd. Foamable vehicle comprising polypropylene glycol alkyl ether and pharmaceutical compositions thereof
EP2100850A1 (en) * 2008-03-11 2009-09-16 Stichting Voor De Technische Wetenschappen Microneedle array and a method for manufacturing microneedles
US20110150765A1 (en) * 2008-10-31 2011-06-23 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Frozen compositions and methods for piercing a substrate
US9586044B2 (en) * 2010-04-28 2017-03-07 Kimberly-Clark Worldwide, Inc. Method for increasing the permeability of an epithelial barrier
PT2563450T (pt) * 2010-04-28 2017-08-28 Kimberly Clark Co Dispositivo para entrega de medicação para a artrite reumatóide
CN102985131B (zh) 2010-04-28 2016-06-29 金伯利-克拉克环球有限公司 用于递送siRNA的医疗装置
JP5860453B2 (ja) 2010-04-28 2016-02-16 キンバリー クラーク ワールドワイド インコーポレイテッド 表面にナノ構造体を含む複合マイクロニードルアレイ
US20120187814A1 (en) 2011-01-25 2012-07-26 Fryling Nicholas A Furniture System and a Frame Assembly for a Furniture System
US20120245445A1 (en) * 2011-03-21 2012-09-27 Michael Darryl Black Glucose Monitoring System
PT2768942T (pt) * 2011-10-17 2020-01-21 Massachusetts Inst Technology Entrega intracelular
US20170246439A9 (en) * 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
EP3574950B1 (en) * 2011-10-27 2021-02-17 Sorrento Therapeutics, Inc. Transdermal delivery of high viscosity bioactive agents
EP4112112A1 (en) * 2012-05-01 2023-01-04 University of Pittsburgh - Of the Commonwealth System of Higher Education Tip-loaded microneedle arrays for transdermal insertion
CN105073179B (zh) 2013-02-28 2019-03-19 索伦托治疗有限公司 经皮药物递送装置
EP2961469A4 (en) 2013-02-28 2016-10-26 Kimberly Clark Co DEVICE FOR DELIVERY OF MEDICAMENT
JP2016517762A (ja) 2013-05-23 2016-06-20 キンバリー クラーク ワールドワイド インコーポレイテッド 開放チャネル断面形状が改善されたマイクロニードル
EP3325080B1 (en) * 2015-07-24 2021-09-01 Sorrento Therapeutics, Inc. Methods for better delivery of active agents to tumors
DK3325081T3 (da) * 2015-07-24 2021-10-11 Sorrento Therapeutics Inc Fremgangsmåder til lymfatisk levering af aktive stoffer

Also Published As

Publication number Publication date
MX2022014634A (es) 2023-01-18
DK3325081T3 (da) 2021-10-11
US20200338329A1 (en) 2020-10-29
AU2020233748A1 (en) 2020-10-08
PL3325081T3 (pl) 2021-12-20
CN107949418B (zh) 2024-07-02
JP2021185160A (ja) 2021-12-09
AU2016297832B2 (en) 2020-07-16
JP2023015135A (ja) 2023-01-31
AU2016297832A1 (en) 2018-02-15
CN107949418A (zh) 2018-04-20
JP7167272B2 (ja) 2022-11-08
US20180193625A1 (en) 2018-07-12
RU2018104104A3 (pt) 2019-10-31
WO2017019535A2 (en) 2017-02-02
US20240181235A1 (en) 2024-06-06
EP3325081A4 (en) 2019-04-10
AU2022275393A1 (en) 2023-01-05
EP3922238A1 (en) 2021-12-15
EP3325081B1 (en) 2021-09-08
KR20180035210A (ko) 2018-04-05
JP6929829B2 (ja) 2021-09-01
MX2018000126A (es) 2018-03-23
RU2719946C2 (ru) 2020-04-23
JP2018522002A (ja) 2018-08-09
AU2020233748B2 (en) 2022-08-25
HUE056424T2 (hu) 2022-02-28
US10737082B2 (en) 2020-08-11
ES2893673T3 (es) 2022-02-09
CA2991459A1 (en) 2017-02-02
EP3325081A2 (en) 2018-05-30
RU2018104104A (ru) 2019-08-26

Similar Documents

Publication Publication Date Title
BR112018001435A2 (pt) métodos para entrega linfática de agentes ativos
BR112018001292A2 (pt) métodos para melhor liberação de agentes ativos a tumores
CL2018001152A1 (es) Composiciones y métodos para el tratamiento del cáncer
MX2018008190A (es) Sistemas y metodos para la administracion transdermica a largo plazo.
MX2018012486A (es) Composiciones para aplicacion topica de compuestos.
BR112017024384A2 (pt) bactérias modificadas para reduzir hiperfenilalaninemia
CL2018003265A1 (es) Modulares del receptor espiro-lactama n-metil-d-aspartato y usos de los mismos.
BR112017014341A2 (pt) método e sistema para tratamento, estabilização, ou redução da gravidade ou progressão de uma doença de fígado gorduroso não alcoólica, e, composição.
CY1124761T1 (el) Ρυθμιστες της δραστικοτητας του συμπληρωματος
BR112018008601A2 (pt) composições compreendendo o canabidiol e segundos agentes terapêuticos para o tratamento de câncer
CL2015003343A1 (es) Composición farmacéutica que comprende un agente terapéutico modificado en base a hemoglobina, para el tratamiento para tratar el cáncer, e imágenes de diagnóstico.
EA201692334A1 (ru) Кортикостероидные композиции для местного применения
TR201901077T4 (tr) Kanser Veya Enfeksiyon Tedavisine Yönelik Birleşik Preparasyonlar
CL2019002251A1 (es) Anticuerpos contra triptasa, composiciones de estos y usos de estos.
BR112019024566A2 (pt) inibidores de pirazol magl
CY1122968T1 (el) Φαρμακευτικη συνθεση η οποια περιλαμβανει μια ενωση διαμινο-ετεροκυκλικου καρβοξαμιδιου ως δραστικο συστατικο
BR112017012504A2 (pt) derivados de piperidina como inibidores de hdac1/2
BR112018015367A2 (pt) carreadores oromucosais de nanofibra para tratamento terapêutico
CL2019001329A1 (es) Composiciones farmacéuticas moduladoras del receptor 7 de 5-hidroxitritpina y métodos de uso.
BR112017009552A8 (pt) Métodos para alvejar o controle transcricional em regiões de super-realçador
BR112017024908A2 (pt) usos terapêuticos da 4-cloroquinurenina
BR112018070497A2 (pt) métodos e formulações farmacêuticas para tratamento de condições oculares
NI201600070A (es) Inhibidores tetracíclicos de autotaxina
BR112017028468A2 (pt) formulação sólida oral, e método para preparar uma formulação sólida oral
CY1122473T1 (el) Βελτιστοποιημενο μεσαλαζiνουχο δισκιο υψηλης δοσης

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: SORRENTO THERAPEUTICS, INC. (US)

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements