MX2014003025A - Compuestos de triazolopiridina como inhibidores de fosfodiesterasa 10a. - Google Patents

Compuestos de triazolopiridina como inhibidores de fosfodiesterasa 10a.

Info

Publication number
MX2014003025A
MX2014003025A MX2014003025A MX2014003025A MX2014003025A MX 2014003025 A MX2014003025 A MX 2014003025A MX 2014003025 A MX2014003025 A MX 2014003025A MX 2014003025 A MX2014003025 A MX 2014003025A MX 2014003025 A MX2014003025 A MX 2014003025A
Authority
MX
Mexico
Prior art keywords
triazolopyridine compounds
pde10a inhibitors
compounds
triazolopyridine
pde10a
Prior art date
Application number
MX2014003025A
Other languages
English (en)
Spanish (es)
Inventor
Alexander Flohr
Katrin Groebke Zbinden
Matthias Koerner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46851999&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2014003025(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2014003025A publication Critical patent/MX2014003025A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MX2014003025A 2011-09-19 2012-09-17 Compuestos de triazolopiridina como inhibidores de fosfodiesterasa 10a. MX2014003025A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11181752 2011-09-19
PCT/EP2012/068203 WO2013041472A1 (en) 2011-09-19 2012-09-17 Triazolopyridine compounds as pde10a inhibitors

Publications (1)

Publication Number Publication Date
MX2014003025A true MX2014003025A (es) 2014-05-28

Family

ID=46851999

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014003025A MX2014003025A (es) 2011-09-19 2012-09-17 Compuestos de triazolopiridina como inhibidores de fosfodiesterasa 10a.

Country Status (19)

Country Link
US (2) US8946427B2 (enExample)
EP (1) EP2758396B1 (enExample)
JP (1) JP2014526533A (enExample)
KR (1) KR101584925B1 (enExample)
CN (1) CN103827114B (enExample)
AU (1) AU2012311713A1 (enExample)
BR (1) BR112014006248A2 (enExample)
CA (1) CA2846758C (enExample)
CL (1) CL2014000641A1 (enExample)
CO (1) CO6900144A2 (enExample)
EA (1) EA201490599A1 (enExample)
ES (1) ES2626801T3 (enExample)
IL (1) IL231403A0 (enExample)
MX (1) MX2014003025A (enExample)
PE (1) PE20141553A1 (enExample)
PH (1) PH12014500499A1 (enExample)
SG (1) SG11201400759RA (enExample)
UA (1) UA108711C2 (enExample)
WO (1) WO2013041472A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2757882B1 (en) 2011-09-22 2020-11-04 Merck Sharp & Dohme Corp. Imidazopyridyl compounds as aldosterone synthase inhibitors
EP2757883B1 (en) 2011-09-22 2021-01-13 Merck Sharp & Dohme Corp. Triazolopyridyl compounds as aldosterone synthase inhibitors
CA2909477A1 (en) 2013-04-30 2014-11-06 F. Hoffmann-La Roche Ag Pd-catalyzed coupling of pyrazole amides
TWI652014B (zh) 2013-09-13 2019-03-01 美商艾佛艾姆希公司 雜環取代之雙環唑殺蟲劑
EP3176168A4 (en) * 2014-07-30 2018-05-02 Mochida Pharmaceutical Co., Ltd. Pyrazole derivative manufacturing method
EP3176167A4 (en) * 2014-07-30 2018-03-28 Mochida Pharmaceutical Co., Ltd. Pyrazole derivative manufacturing method
WO2016144351A1 (en) 2015-03-11 2016-09-15 E. I. Du Pont De Nemours And Company Heterocycle-substituted bicyclic azole pesticides
CN107743486B (zh) 2015-03-12 2021-04-09 Fmc公司 杂环取代的二环唑杀有害生物剂
BR112018007034B1 (pt) 2015-10-08 2022-10-11 Fmc Corporation Composto, composição, método para controlar uma praga de invertebrados e semente revestida
BR112020003481B1 (pt) * 2017-08-22 2023-12-05 Bayer Aktiengesellschaft Derivados de heterocicleno, seus usos, formulação agroquímica, e métodos para controlar pragas animais e para proteger sementes ou uma planta germinativa de pragas
CN113906024B (zh) 2019-05-27 2023-10-20 日本农药株式会社 交联部有氮原子的缩合杂环化合物或其盐类及含该化合物的农业园艺用杀虫剂及其使用方法
AR119140A1 (es) 2019-06-13 2021-11-24 Pi Industries Ltd Compuestos heterocíclicos fusionados y su uso como agentes de control de plagas
CN110396157B (zh) * 2019-08-07 2021-07-30 广州市建筑科学研究院有限公司 缓释型聚羧酸纳米减水剂及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355653B1 (en) * 1999-09-06 2002-03-12 Hoffmann-La Roche Inc. Amino-triazolopyridine derivatives
JP2007508241A (ja) 2003-07-31 2007-04-05 バイエル・フアーマシユーチカルズ・コーポレーシヨン Ｐｄｅ１０ａ阻害剤を用いる糖尿病および関連障害の処置方法
NL2000397C2 (nl) * 2006-01-05 2007-10-30 Pfizer Prod Inc Bicyclische heteroarylverbindingen als PDE10 inhibitoren.
JPWO2010035745A1 (ja) * 2008-09-25 2012-02-23 杏林製薬株式会社 ヘテロ環ビアリール誘導体及びそれらを有効成分とするｐｄｅ阻害剤
WO2010059836A1 (en) * 2008-11-20 2010-05-27 Decode Genetics Ehf Substituted aza-bridged bicyclics for cardiovascular and cns disease
US8685967B2 (en) * 2009-04-07 2014-04-01 Merck Sharp & Dohme Corp. Substituted triazolopyridines and analogs thereof
PL2480546T3 (pl) * 2009-09-24 2015-05-29 Hoffmann La Roche Pochodne imidazopirydyny i imidazopirymidyny jako inhibitory fosfodiesterazy 10A
CN102696239B (zh) 2009-11-24 2020-08-25 诺基亚技术有限公司 一种设备
TWI487705B (zh) * 2009-12-17 2015-06-11 Lundbeck & Co As H 作為ｐｄｅ１０ａ酵素抑制劑之雜芳香族芳基三唑衍生物
TWI485151B (zh) * 2009-12-17 2015-05-21 Lundbeck & Co As H 作為ｐｄｅ１０ａ酵素抑制劑之雜芳香族苯基咪唑衍生物
TW201200516A (en) * 2009-12-17 2012-01-01 Lundbeck & Co As H Phenylimidazole derivatives comprising an ethynylene linker as PDE10A enzyme inhibitors

Also Published As

Publication number Publication date
CA2846758C (en) 2017-09-12
CN103827114A (zh) 2014-05-28
US8946427B2 (en) 2015-02-03
UA108711C2 (uk) 2015-05-25
US9227970B2 (en) 2016-01-05
AU2012311713A1 (en) 2014-03-13
JP2014526533A (ja) 2014-10-06
KR20140075716A (ko) 2014-06-19
US20140303141A1 (en) 2014-10-09
CO6900144A2 (es) 2014-03-20
PH12014500499A1 (en) 2014-04-14
KR101584925B1 (ko) 2016-01-12
EP2758396A1 (en) 2014-07-30
PE20141553A1 (es) 2014-10-30
IL231403A0 (en) 2014-04-30
ES2626801T3 (es) 2017-07-26
SG11201400759RA (en) 2014-07-30
US20150099735A1 (en) 2015-04-09
EA201490599A1 (ru) 2014-07-30
NZ621597A (en) 2015-04-24
CA2846758A1 (en) 2013-03-28
CN103827114B (zh) 2016-08-24
CL2014000641A1 (es) 2014-11-14
WO2013041472A1 (en) 2013-03-28
EP2758396B1 (en) 2017-03-29
BR112014006248A2 (pt) 2017-04-11

Similar Documents

Publication Publication Date Title
PH12014500499A1 (en) Triazolopyridine compounds as pde10a inhibitors
PH12012501772A1 (en) N-(imidazopyrimidin-7-yl)-heteroarylamide derivatives and their use as pde10a inhibitors
PH12013500942A1 (en) Triazolopyridine compounds
PH12014502294A1 (en) Triazolo compounds as pde10 inhibitors
MX2012007536A (es) Derivados de heteroarilo que contienen nitrogeno.
MX2013008212A (es) Derivados de 7-azaindol.
MX338327B (es) Inhibidores de cdk.
MX336381B (es) Boronatos como inhibidores de arginasa.
IN2015DN01156A (enExample)
PH12012502335A1 (en) Nitrogen containing heteroaryl compounds
MY170878A (en) [1,2,3] triazolo [4,5-d] pyrimidine derivatives as agonists of the cannabinoid receptor 2
JO3115B1 (ar) مركبات بيريدازينون واستخدامها كمثبطات daao
PH12013500005A1 (en) Indolizine derivatives, process for the preparation thereof and therapeutic use thereof
PH12013502434A1 (en) Substituted pyridopyrazines as novel syk inhibitors
MX2014012477A (es) Inhibidores pirrolopirazona de tanquirasa.
MX2014002682A (es) Modulares de la fosfodiesterasa 10 (pde 10).
PH12012500355A1 (en) Imidazopyridine or imidazopyrimidine derivatives as phosphodiesterase 10a inhibitors
PH12014501026A1 (en) [1, 2, 3]triazolo[4,5-d] pyrimidine derivatives as agonists of the cannabinoid receptor 2 agonists
GB201209587D0 (en) Therapeutic compounds
MX349373B (es) Nuevos derivados de pirazina.
PH12015501175A1 (en) Substituted pyridopyrazines as syk inhibitors
MX2014014308A (es) Pirrolidino heterociclos.
PH12015500399A1 (en) Azaindolines
EA201391586A1 (ru) ИНГИБИТОРЫ 17α-ГИДРОКСИЛАЗЫ/C-ЛИАЗЫ
MX346090B (es) Derivados de pirrolidina usados como inhibidores de catepsina.

Legal Events

Date Code Title Description
FG Grant or registration