MX2013007381A - Composiciones farmaceuticas de tenecteplasa. - Google Patents

Composiciones farmaceuticas de tenecteplasa.

Info

Publication number
MX2013007381A
MX2013007381A MX2013007381A MX2013007381A MX2013007381A MX 2013007381 A MX2013007381 A MX 2013007381A MX 2013007381 A MX2013007381 A MX 2013007381A MX 2013007381 A MX2013007381 A MX 2013007381A MX 2013007381 A MX2013007381 A MX 2013007381A
Authority
MX
Mexico
Prior art keywords
tenecteplase
pharmaceutical compositions
compositions
tnk
treatment
Prior art date
Application number
MX2013007381A
Other languages
English (en)
Other versions
MX356199B (es
Inventor
Maheshwari Kumar Mishra
Pritiranjan Bhandari
Sanjay Singh
Original Assignee
Gennova Biopharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46313261&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2013007381(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gennova Biopharmaceuticals Ltd filed Critical Gennova Biopharmaceuticals Ltd
Publication of MX2013007381A publication Critical patent/MX2013007381A/es
Publication of MX356199B publication Critical patent/MX356199B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21068—Tissue plasminogen activator (3.4.21.68), i.e. tPA

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describen composiciones farmacéuticas de tenecteplasa que son seguras y efectivas en el tratamiento de accidente cerebrovascular isquémico agudo en comparación con las composiciones conocidas. Las composiciones de la presente invención se conciben en base a una serie de ensayos de prueba en las diferentes cantidades de TNK y el aislamiento de una cantidad específica que es óptimamente adecuada en términos del efecto deseado de TNK en el tratamiento de accidente cerebrovascular isquémico agudo.
MX2013007381A 2010-12-23 2011-12-16 Composiciones farmacéuticas de tenecteplasa. MX356199B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN3516MU2010 2010-12-23
PCT/IN2011/000863 WO2012085933A1 (en) 2010-12-23 2011-12-16 Pharmaceutical compositions of tenecteplase

Publications (2)

Publication Number Publication Date
MX2013007381A true MX2013007381A (es) 2013-08-29
MX356199B MX356199B (es) 2018-05-18

Family

ID=46313261

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013007381A MX356199B (es) 2010-12-23 2011-12-16 Composiciones farmacéuticas de tenecteplasa.

Country Status (17)

Country Link
US (2) US20130323227A1 (es)
EP (1) EP2654770B1 (es)
JP (1) JP6375112B2 (es)
CN (1) CN103391785A (es)
AU (1) AU2011346515B2 (es)
BR (1) BR112013015914B1 (es)
CO (1) CO6721059A2 (es)
DK (1) DK2654770T3 (es)
EA (1) EA026017B1 (es)
ES (1) ES2687850T3 (es)
LT (1) LT2654770T (es)
MX (1) MX356199B (es)
MY (1) MY171723A (es)
NZ (1) NZ611706A (es)
PL (1) PL2654770T3 (es)
PT (1) PT2654770T (es)
WO (1) WO2012085933A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7086601B2 (ja) * 2014-10-21 2022-06-20 ジェンノヴァ バイオファーマシューティカルズ リミテッド 組換えｔｎｋ－ｔｐａ（テネクテプラーゼ）の単離及び商業生産のための新規精製方法
EP3624832A1 (en) * 2017-05-16 2020-03-25 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of acute ischemic stroke
EP3802780A4 (en) * 2018-06-01 2022-03-23 Gennova Biopharmaceuticals Limited METHOD FOR PRODUCING RECOMBINANT TNK-TPA BY A PACKED BED INFUSION SYSTEM

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10230752A1 (de) * 2002-07-09 2004-01-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkompositionen auf der Basis von Magnesiumsalzen und Fibrinolytika
US20070014779A1 (en) * 2002-11-14 2007-01-18 Genentech, Inc. Plasminogen activator variant formulations
WO2006094120A2 (en) * 2005-03-02 2006-09-08 The Regents Of The University Of California Treatment for embolic stroke
US20070166299A1 (en) * 2005-03-02 2007-07-19 The Regents Of The University Of California Treatment for embolic stroke
CA2661012C (en) * 2006-08-29 2019-03-19 Genentech, Inc. Method of treating stroke with thrombolytic agent
US8916148B2 (en) * 2006-11-07 2014-12-23 Genentech, Inc. Tissue plasminogen activator variant uses
EP2014760A1 (en) * 2007-06-13 2009-01-14 CMC Biopharmaceuticals A/S A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process

Also Published As

Publication number Publication date
WO2012085933A1 (en) 2012-06-28
EP2654770A1 (en) 2013-10-30
US20160310580A1 (en) 2016-10-27
EP2654770B1 (en) 2018-07-11
AU2011346515A1 (en) 2013-07-04
PT2654770T (pt) 2018-10-19
BR112013015914B1 (pt) 2021-06-08
EA026017B1 (ru) 2017-02-28
JP2014502608A (ja) 2014-02-03
LT2654770T (lt) 2018-09-10
US20130323227A1 (en) 2013-12-05
ES2687850T3 (es) 2018-10-29
AU2011346515B2 (en) 2017-01-19
US9943575B2 (en) 2018-04-17
PL2654770T3 (pl) 2018-12-31
DK2654770T3 (en) 2018-10-29
BR112013015914A2 (pt) 2016-10-11
EP2654770A4 (en) 2014-05-21
MX356199B (es) 2018-05-18
NZ611706A (en) 2015-04-24
MY171723A (en) 2019-10-24
CO6721059A2 (es) 2013-07-31
CN103391785A (zh) 2013-11-13
EA201300746A1 (ru) 2013-11-29
JP6375112B2 (ja) 2018-08-15

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