MX2013006202A - Metodo de radioconjugacion. - Google Patents
Metodo de radioconjugacion.Info
- Publication number
- MX2013006202A MX2013006202A MX2013006202A MX2013006202A MX2013006202A MX 2013006202 A MX2013006202 A MX 2013006202A MX 2013006202 A MX2013006202 A MX 2013006202A MX 2013006202 A MX2013006202 A MX 2013006202A MX 2013006202 A MX2013006202 A MX 2013006202A
- Authority
- MX
- Mexico
- Prior art keywords
- radioconjugation
- precursors
- radiopharmaceuticals
- radioisotope
- labelling
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000002243 precursor Substances 0.000 abstract 2
- 238000011503 in vivo imaging Methods 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 239000012217 radiopharmaceutical Substances 0.000 abstract 1
- 229940121896 radiopharmaceutical Drugs 0.000 abstract 1
- 230000002799 radiopharmaceutical effect Effects 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/008—Peptides; Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/02—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/13—Labelling of peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/534—Production of labelled immunochemicals with radioactive label
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1020314.9A GB201020314D0 (en) | 2010-12-01 | 2010-12-01 | Apoptosis pet imaging agents |
| US201161476805P | 2011-04-19 | 2011-04-19 | |
| GBGB1106593.5A GB201106593D0 (en) | 2011-04-19 | 2011-04-19 | Radioconjugation method |
| PCT/EP2011/071506 WO2012072736A2 (en) | 2010-12-01 | 2011-12-01 | Radioconjugation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2013006202A true MX2013006202A (es) | 2013-07-29 |
Family
ID=45063153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013006202A MX2013006202A (es) | 2010-12-01 | 2011-12-01 | Metodo de radioconjugacion. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9493504B2 (enExample) |
| EP (2) | EP3395373B1 (enExample) |
| JP (1) | JP6231882B2 (enExample) |
| KR (1) | KR20130119957A (enExample) |
| CN (2) | CN104984372B (enExample) |
| AU (1) | AU2011334881A1 (enExample) |
| BR (1) | BR112013013283A2 (enExample) |
| CA (1) | CA2819347A1 (enExample) |
| ES (2) | ES2675102T3 (enExample) |
| MX (1) | MX2013006202A (enExample) |
| RU (1) | RU2013122649A (enExample) |
| WO (1) | WO2012072736A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3395373B1 (en) * | 2010-12-01 | 2022-10-19 | GE Healthcare Limited | Method for labelling a biological targeting molecule via conjugation with a radioisotope suitable for pet or spect imaging |
| GB201314936D0 (en) * | 2013-08-21 | 2013-10-02 | Ge Healthcare Ltd | Radiolabelling method |
| GB201322456D0 (en) | 2013-12-18 | 2014-02-05 | Ge Healthcare Ltd | Radiotracer compositions and methods |
| GB201322451D0 (en) * | 2013-12-18 | 2014-02-05 | Ge Healthcare Ltd | Purification method and compositions |
| CA3085407A1 (en) * | 2018-01-26 | 2019-08-01 | F. Hoffmann-La Roche Ag | Radiolabelled oligonucleotides and process for their preparation |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996040662A2 (en) | 1995-06-07 | 1996-12-19 | Cellpro, Incorporated | Aminooxy-containing linker compounds and their application in conjugates |
| GB0305704D0 (en) * | 2003-03-13 | 2003-04-16 | Amersham Plc | Radiofluorination methods |
| EP1713508A2 (en) * | 2004-01-29 | 2006-10-25 | Biosynexus Incorporated | Use of amino-oxy functional groups in the preparation of vaccine conjugates |
| GB0420344D0 (en) | 2004-09-14 | 2004-10-13 | Amersham Plc | Diagnostic compounds |
| GB0420365D0 (en) | 2004-09-14 | 2004-10-13 | Hammersmith Imanet Ltd | Radiolabelled insulin |
| EP2125039A2 (en) | 2006-12-18 | 2009-12-02 | GE Healthcare AS | Synthesis of a radiofluorinated peptide using photolabile protecting groups |
| EP2114464A2 (en) * | 2006-12-28 | 2009-11-11 | GE Healthcare AS | Radiofluorination methods |
| US8545809B2 (en) * | 2007-01-11 | 2013-10-01 | Immunomedics, Inc. | Methods and compositions for improved 18F labeling of proteins, peptides and other molecules |
| US20080274046A1 (en) * | 2007-02-20 | 2008-11-06 | Christian Prenant | Radiolabelling |
| GB0803477D0 (en) * | 2008-02-26 | 2008-04-02 | Ge Healthcare As | Therapy selection method |
| EP3395373B1 (en) * | 2010-12-01 | 2022-10-19 | GE Healthcare Limited | Method for labelling a biological targeting molecule via conjugation with a radioisotope suitable for pet or spect imaging |
-
2011
- 2011-12-01 EP EP18167523.2A patent/EP3395373B1/en active Active
- 2011-12-01 JP JP2013541350A patent/JP6231882B2/ja active Active
- 2011-12-01 BR BR112013013283A patent/BR112013013283A2/pt not_active IP Right Cessation
- 2011-12-01 MX MX2013006202A patent/MX2013006202A/es unknown
- 2011-12-01 WO PCT/EP2011/071506 patent/WO2012072736A2/en not_active Ceased
- 2011-12-01 EP EP11788862.8A patent/EP2646060B1/en active Active
- 2011-12-01 ES ES11788862.8T patent/ES2675102T3/es active Active
- 2011-12-01 RU RU2013122649/04A patent/RU2013122649A/ru not_active Application Discontinuation
- 2011-12-01 AU AU2011334881A patent/AU2011334881A1/en not_active Abandoned
- 2011-12-01 US US13/991,340 patent/US9493504B2/en active Active
- 2011-12-01 KR KR1020137016889A patent/KR20130119957A/ko not_active Withdrawn
- 2011-12-01 CA CA2819347A patent/CA2819347A1/en not_active Abandoned
- 2011-12-01 ES ES18167523T patent/ES2929507T3/es active Active
- 2011-12-01 CN CN201510440109.1A patent/CN104984372B/zh active Active
- 2011-12-01 CN CN201180057989.4A patent/CN103269725B/zh active Active
-
2016
- 2016-11-01 US US15/340,743 patent/US20170044080A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2929507T3 (es) | 2022-11-29 |
| RU2013122649A (ru) | 2015-01-10 |
| US9493504B2 (en) | 2016-11-15 |
| JP6231882B2 (ja) | 2017-11-15 |
| JP2014500883A (ja) | 2014-01-16 |
| EP3395373B1 (en) | 2022-10-19 |
| CN104984372B (zh) | 2018-11-09 |
| CN104984372A (zh) | 2015-10-21 |
| EP3395373A1 (en) | 2018-10-31 |
| AU2011334881A1 (en) | 2013-06-06 |
| CN103269725A (zh) | 2013-08-28 |
| EP2646060A2 (en) | 2013-10-09 |
| WO2012072736A2 (en) | 2012-06-07 |
| CN103269725B (zh) | 2015-09-23 |
| CA2819347A1 (en) | 2012-06-07 |
| WO2012072736A3 (en) | 2012-10-18 |
| US20170044080A1 (en) | 2017-02-16 |
| ES2675102T3 (es) | 2018-07-06 |
| KR20130119957A (ko) | 2013-11-01 |
| BR112013013283A2 (pt) | 2016-11-22 |
| EP2646060B1 (en) | 2018-05-30 |
| US20130259803A1 (en) | 2013-10-03 |
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