MX2013004522A - Control de patogenos y parasitos. - Google Patents

Control de patogenos y parasitos.

Info

Publication number
MX2013004522A
MX2013004522A MX2013004522A MX2013004522A MX2013004522A MX 2013004522 A MX2013004522 A MX 2013004522A MX 2013004522 A MX2013004522 A MX 2013004522A MX 2013004522 A MX2013004522 A MX 2013004522A MX 2013004522 A MX2013004522 A MX 2013004522A
Authority
MX
Mexico
Prior art keywords
parasites
pathogens
control
expression
silencing rna
Prior art date
Application number
MX2013004522A
Other languages
English (en)
Inventor
Anil Kumar
Richard Sayre
Original Assignee
Donald Danforth Plant Sci Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Donald Danforth Plant Sci Ct filed Critical Donald Danforth Plant Sci Ct
Publication of MX2013004522A publication Critical patent/MX2013004522A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/153—Nucleic acids; Hydrolysis products or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8214—Plastid transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Pest Control & Pesticides (AREA)
  • Animal Husbandry (AREA)
  • Insects & Arthropods (AREA)
  • Food Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La presente invención se refiere al control genético de parásitos y patógenos vía la expresión de RNA silenciador en plantas transgénicas, incluyendo microalgas. En un aspecto, la invención explota la capacidad de plantas para expresar el RNA silenciador en una forma dentro de los cloroplastos que es captado eficientemente, después de la ingestión, donde puede actuar para suprimir la expresión de genes objetivo dentro del patógeno o parásito.
MX2013004522A 2010-10-22 2011-10-24 Control de patogenos y parasitos. MX2013004522A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40577010P 2010-10-22 2010-10-22
PCT/US2011/057476 WO2012054919A2 (en) 2010-10-22 2011-10-24 Control of pathogens and parasites

Publications (1)

Publication Number Publication Date
MX2013004522A true MX2013004522A (es) 2013-08-27

Family

ID=45975933

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013004522A MX2013004522A (es) 2010-10-22 2011-10-24 Control de patogenos y parasitos.

Country Status (8)

Country Link
US (1) US20130315883A1 (es)
EP (1) EP2629599A4 (es)
CN (1) CN103269579A (es)
AU (1) AU2011316776A1 (es)
CA (1) CA2820536A1 (es)
CL (1) CL2013001102A1 (es)
MX (1) MX2013004522A (es)
WO (1) WO2012054919A2 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015135039A1 (en) * 2014-03-12 2015-09-17 The University Of Sydney Sirna production in plastids of higher plants
EP3140401A2 (en) 2014-05-04 2017-03-15 Forrest Innovations Ltd. Compositions for mosquito control and uses of same
BR112017012580A2 (pt) * 2014-12-19 2017-12-26 Max Planck Gesellschaft proteção de plantas de uma praga ou patógeno pela expressão de rnas de filamento duplo no plastídio
CN104497118B (zh) * 2014-12-29 2017-08-11 清华大学 一种昆虫蛋白Hig及其编码基因和应用
EP3322798A4 (en) * 2015-07-14 2019-03-06 Transalgae Israel Ltd. TRANSGENIC MICROALGUES AND THEIR USE AS A DELIVERY OF INTERFERENCE RNA MOLECULE DELIVERY
WO2018053451A1 (en) * 2016-09-16 2018-03-22 Pebble Labs Novel paratransgenic system for the biocontrol of disease-transmitting mosquitos
CN110241114B (zh) * 2019-03-20 2023-09-22 中国热带农业科学院热带生物技术研究所 一种可防控蚊虫的双链rna及其应用
CN110042102B (zh) * 2019-03-20 2022-12-06 中国热带农业科学院热带生物技术研究所 一种可防蚊控蚊的双链rna、表达载体及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0306715D0 (en) * 2003-03-24 2003-04-30 Novartis Ag Organic compounds
JP5183064B2 (ja) * 2003-07-02 2013-04-17 エムユーエスシー ファウンデイション フォー リサーチ デべロップメント 甲殻類動物、及び他の無脊椎動物における、ｄｓＲＮＡで誘導された特異的、及び非特異的免疫、及びそこで使用する生物送達媒体
CN1860220A (zh) * 2003-07-02 2006-11-08 南卡罗来纳医科大学研究发展基金会 dsRNA 诱导的在甲壳动物和其它无脊椎动物中的特异性和非特异性免疫及其中所用的生物送递载体
AU2005213981A1 (en) * 2004-02-06 2005-09-01 Advanced Bionutrition Corporation RNA-mediated interference to control disease in terrestrial and aquaculture animals
DE102004024184A1 (de) * 2004-05-13 2006-01-26 Basf Plant Science Gmbh Neue Nukleinsäuresequenzen und deren Verwendung in Verfahren zum Erreichen einer Pathogenresistenz in Pflanzen
CN101107362A (zh) * 2004-10-21 2008-01-16 文甘扎公司 用于赋予对植物病害生物和植物病原体抗性的方法和材料
CN101048505A (zh) * 2004-10-25 2007-10-03 德福根有限公司 用于递送双链rna至有害生物的包含至少一个适配子的多结构域rna分子
US8772254B2 (en) * 2004-10-25 2014-07-08 Devgen N.V. Method and constructs for delivering double stranded RNA to pest organisms
US8404927B2 (en) * 2004-12-21 2013-03-26 Monsanto Technology Llc Double-stranded RNA stabilized in planta
US20080107652A1 (en) * 2006-08-25 2008-05-08 Science & Technology Corporation @ University Of New Mexico Stc.Unm Methods and compositions for control of disease in aquaculture

Also Published As

Publication number Publication date
CL2013001102A1 (es) 2014-04-04
AU2011316776A1 (en) 2013-06-06
EP2629599A4 (en) 2014-04-02
EP2629599A2 (en) 2013-08-28
CN103269579A (zh) 2013-08-28
WO2012054919A3 (en) 2012-09-20
US20130315883A1 (en) 2013-11-28
WO2012054919A2 (en) 2012-04-26
CA2820536A1 (en) 2012-04-26

Similar Documents

Publication Publication Date Title
MX2013004522A (es) Control de patogenos y parasitos.
MX2019012252A (es) Composiciones y metodos para inhibir la expresion del gen alas1.
MX2021015290A (es) Composiciones y metodos para inhibicion de genes para apolipoproteina c-iii (apoc3).
CL2015000565A1 (es) Método de integración de transgenes por ingeniería genética para producir células de planta transgénica.
HK1212376A1 (en) Rna-guided human genome engineering rna
WO2014165612A3 (en) Methods and compositions for integration of an exogenous sequence within the genome of plants
HK1207111A1 (en) Methods and compositions for controlling gene expression by rna processing rna
MX2018013216A (es) Composiciones y metodos para inhibir la expresion del gen de proteasa transmembrana, serina 6 (tmprss6).
CL2013001850A1 (es) Composicion que contiene bacterias que comprenden una mutuacion sobre el gen swra, y metodo para mejorar elcrecimiento de las plantas , promover la salud o controlar enfermedades que las afecten basado en la aplicacion de dicha composicion.
MY174390A (en) Engineered zinc finger proteins targeting plant genes involved in fatty acid biosynthesis
BR112013018836A2 (pt) "métodos de manipulação, obtenção, elevação e aumento em uma planta que compreende a expressão de gene modificado"
IL229003B (en) Diploid, fertile and self-fertilizing potato varieties containing at least one positive ergonomic trait or gene transferred by genetic transformation
EP2464336A4 (en) COMPOSITIONS FORMULATED IN LIPIDS AND METHODS OF INHIBITING THE EXPRESSION OF EBOLA VIRUS GENE
EP2382330A4 (en) TARGETED NUCLEIC ACID AMPLIFICATION BY CROSS-PRIMING
IN2015DN04148A (es)
IN2014DN03473A (es)
WO2012082832A3 (en) Lepidopteran moth control using double-stranded rna constructs
MX2022001017A (es) Composiciones y metodos para inhibir la expresion del gen de sintasa de acido 5'-aminolevulinico 1 (alas1).
WO2013012729A3 (en) Novel plant terminator sequences
MX2013014308A (es) Metodos y medios para modificar un genoma vegetal en un sitio preseleccionado.
WO2011106001A3 (en) Autoluminescent plants including the bacterial lux operon and methods of making same
AR098819A1 (es) Método y composiciones para el control de insectos plaga en plantas por medio del silenciamiento de genes de la familia de la quitina sintasa y de la vitelogenina así como alternativamente por la expresión del gen de una toxina cry
EP2599382A4 (en) METHOD FOR GENE TRANSFER IN PLANT BELONGING TO HORDEUM GENUS USING AGROBACTERIUM BACTERIUM, AND PROCESS FOR PRODUCTION OF TRANSGENIC PLANT FOR PLANT BELONGING TO HORDEUM GENUS
WO2015008160A3 (en) Modified algae strain and method of triacylglycerol accumulation using said strain
CL2013003466A1 (es) Construcción de arn que comprende una secuencia de segmento sentido y una antisentido del gen p0 del genoma del virus del amarilleo moderado de la remolacha (bmyv), metodo para inducir tolerancia al virus bmyv.