MX2012003196A - Composicion oftalmica acuosa inyectable y metodo de uso para la misma. - Google Patents

Composicion oftalmica acuosa inyectable y metodo de uso para la misma.

Info

Publication number
MX2012003196A
MX2012003196A MX2012003196A MX2012003196A MX2012003196A MX 2012003196 A MX2012003196 A MX 2012003196A MX 2012003196 A MX2012003196 A MX 2012003196A MX 2012003196 A MX2012003196 A MX 2012003196A MX 2012003196 A MX2012003196 A MX 2012003196A
Authority
MX
Mexico
Prior art keywords
ophthalmic composition
injectable aqueous
aqueous ophthalmic
use therefor
mass
Prior art date
Application number
MX2012003196A
Other languages
English (en)
Inventor
Masood A Chowhan
Wesley Wehsin Han
Thomas C Hohman
Ernesto J Castillo
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of MX2012003196A publication Critical patent/MX2012003196A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invención se dirige a la disposición de una composición oftálmica adecuada para inyección intravítrea. La composición incluye una cantidad de agente formador de complejos que reacciona por uno o más componentes endógenos (por ejemplo, ácido hialurónico) en el ojo para formar una masa de viscosidad mejorada. Esta masa puede ayudar a crear un perfil de liberación deseable de agente terapéutico.
MX2012003196A 2009-09-23 2010-09-21 Composicion oftalmica acuosa inyectable y metodo de uso para la misma. MX2012003196A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24491609P 2009-09-23 2009-09-23
PCT/US2010/049623 WO2011037908A1 (en) 2009-09-23 2010-09-21 Injectable aqueous ophthalmic composition and method of use therefor

Publications (1)

Publication Number Publication Date
MX2012003196A true MX2012003196A (es) 2012-04-30

Family

ID=43034434

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012003196A MX2012003196A (es) 2009-09-23 2010-09-21 Composicion oftalmica acuosa inyectable y metodo de uso para la misma.

Country Status (15)

Country Link
US (3) US20110071091A1 (es)
EP (1) EP2480205B1 (es)
JP (2) JP5732058B2 (es)
KR (2) KR20120069741A (es)
CN (1) CN102695497B (es)
AR (1) AR078293A1 (es)
AU (1) AU2010298480B2 (es)
BR (1) BR112012006642A2 (es)
CA (1) CA2772795A1 (es)
ES (1) ES2568462T3 (es)
MX (1) MX2012003196A (es)
PL (1) PL2480205T3 (es)
TW (1) TWI492769B (es)
WO (1) WO2011037908A1 (es)
ZA (1) ZA201201438B (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1888548B1 (en) 2005-05-26 2012-08-22 Neuron Systems, Inc Quinoline derivative for the treatment of retinal diseases
TWI492769B (zh) 2009-09-23 2015-07-21 Alcon Res Ltd 可注射的水性眼用組成物及其使用之方法
US20140178327A1 (en) 2012-12-21 2014-06-26 Coopervision International Holding Company, Lp Antimicrobial Ophthalmic Devices
US9498035B2 (en) 2012-12-21 2016-11-22 Coopervision International Holding Company, Lp Silicone hydrogel contact lenses for sustained release of beneficial polymers
EP2948149A4 (en) 2013-01-23 2016-12-14 Aldeyra Therapeutics Inc BY TOXIC ALDEHYDIC DISEASES AND TREATMENT
US20150164882A1 (en) 2013-07-22 2015-06-18 Imprimis Pharmaceuticals, Inc. Pharmaceutical compositions for intraocular administration and methods for fabricating thereof
US20160279055A1 (en) * 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
US20170119885A1 (en) * 2014-04-28 2017-05-04 Hampton Technologies Ophthalmic compositions and methods for treating eyes
US20150366311A1 (en) 2014-06-19 2015-12-24 Coopervision International Holding Company, Lp Protection of Contact Lenses from Microbial Contamination Caused by Handling
WO2016197005A1 (en) * 2015-06-05 2016-12-08 Kato Pharmaceuticals, Inc. Extended release urea compositions
KR102664994B1 (ko) 2015-08-21 2024-05-13 알데이라 테라퓨틱스, 아이엔씨. 중수소화 화합물 및 이의 용도
WO2017035408A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Compounds for treatment of immune and inflammatory disorders
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
CN109152774A (zh) 2016-05-09 2019-01-04 奥尔德拉医疗公司 眼部炎性病症和疾病的组合治疗
RU2018145364A (ru) 2016-06-27 2020-07-28 Ачиллион Фармасьютикалс, Инк. Хиназолиновые и индольные соединения для лечения медицинских нарушений
MX2020003425A (es) 2017-10-10 2020-07-29 Aldeyra Therapeutics Inc Tratamiento de trastornos inflamatorios.
US12006298B2 (en) 2018-08-06 2024-06-11 Aldeyra Therapeutics, Inc. Polymorphic compounds and uses thereof
EP3841086A4 (en) 2018-08-20 2022-07-27 Achillion Pharmaceuticals, Inc. PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF MEDICAL DISORDERS RELATED TO COMPLEMENT FACTOR D
EP3866773A4 (en) 2018-10-16 2022-10-26 Georgia State University Research Foundation, Inc. CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL CONDITIONS
WO2020118045A1 (en) * 2018-12-05 2020-06-11 Aldeyra Therapeutics, Inc. Injectable formulations

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Publication number Priority date Publication date Assignee Title
AU604236B2 (en) * 1986-04-28 1990-12-13 Iolab, Inc. Intraocular dosage compositions and method of use
US7947295B2 (en) * 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
JP5436778B2 (ja) 2004-09-24 2014-03-05 ハーキュリーズ・インコーポレーテッド スキンケア製品のための高い置換度を有するカチオン性ポリガラクトマンナン
BRPI0608152A2 (pt) * 2005-02-09 2009-11-10 Macusight Inc formulações para tratamento ocular
CN100433805C (zh) * 2005-06-29 2008-11-12 上海广电（集团）有限公司中央研究院 一种数字电视接收机及其信号传递方法
US8168584B2 (en) * 2005-10-08 2012-05-01 Potentia Pharmaceuticals, Inc. Methods of treating age-related macular degeneration by compstatin and analogs thereof
EP1951279B1 (en) * 2005-10-08 2017-04-12 Apellis Pharmaceuticals, Inc. Compstatin and analogs thereof for eye disorders
KR20140093764A (ko) 2006-02-09 2014-07-28 산텐 세이야꾸 가부시키가이샤 안정한 제제와 그 제조 및 사용 방법
US20110182877A1 (en) * 2007-10-02 2011-07-28 Potentia Pharmaceuticals, Inc. Sustained delivery of compstatin analogs from gels
EP2349339A4 (en) * 2008-10-16 2015-01-07 Kathleen Cogan Farinas EXTENDED MEDICATION DELIVERY SYSTEM
US8530189B2 (en) 2008-10-16 2013-09-10 Kathleen Cogan Farinas Sustained drug delivery system
TWI492769B (zh) 2009-09-23 2015-07-21 Alcon Res Ltd 可注射的水性眼用組成物及其使用之方法
CN102939074A (zh) * 2010-05-05 2013-02-20 爱尔康研究有限公司 稳定的眼科半乳甘露聚糖制剂

Also Published As

Publication number Publication date
AU2010298480A1 (en) 2012-03-29
WO2011037908A1 (en) 2011-03-31
JP2013505934A (ja) 2013-02-21
US20160361254A1 (en) 2016-12-15
EP2480205B1 (en) 2016-03-16
AR078293A1 (es) 2011-10-26
CN102695497B (zh) 2016-01-06
BR112012006642A2 (pt) 2016-05-03
EP2480205A1 (en) 2012-08-01
TWI492769B (zh) 2015-07-21
PL2480205T3 (pl) 2016-09-30
JP2015129194A (ja) 2015-07-16
US9446093B2 (en) 2016-09-20
ES2568462T3 (es) 2016-04-29
JP5732058B2 (ja) 2015-06-10
AU2010298480B2 (en) 2014-08-07
US20110071091A1 (en) 2011-03-24
KR20120069741A (ko) 2012-06-28
US20140094419A1 (en) 2014-04-03
ZA201201438B (en) 2013-05-29
TW201111003A (en) 2011-04-01
CA2772795A1 (en) 2011-03-31
CN102695497A (zh) 2012-09-26
KR20170008895A (ko) 2017-01-24

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