MX2012000949A - Terapias de combinacion con moduladores de ck2. - Google Patents

Terapias de combinacion con moduladores de ck2.

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Publication number
MX2012000949A
MX2012000949A MX2012000949A MX2012000949A MX2012000949A MX 2012000949 A MX2012000949 A MX 2012000949A MX 2012000949 A MX2012000949 A MX 2012000949A MX 2012000949 A MX2012000949 A MX 2012000949A MX 2012000949 A MX2012000949 A MX 2012000949A
Authority
MX
Mexico
Prior art keywords
modulators
combination therapies
neoplastic
autoimmune
inflammatory
Prior art date
Application number
MX2012000949A
Other languages
English (en)
Inventor
Denis Drygin
Caroline B Ho
Joshua R Bliesath
Christopher B Proffitt
Kenna Anderes
Sean O Brien
William G Rice
Original Assignee
Cylene Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cylene Pharmaceuticals Inc filed Critical Cylene Pharmaceuticals Inc
Publication of MX2012000949A publication Critical patent/MX2012000949A/es

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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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Abstract

La presente solicitud está generalmente dirigida a compuestos, composiciones y métodos de terapia de combinación para el tratamiento de trastornos neoplásicos, inflamatorios, autoinmunes, o infecciosos.
MX2012000949A 2009-07-23 2010-07-07 Terapias de combinacion con moduladores de ck2. MX2012000949A (es)

Applications Claiming Priority (4)

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US22812109P 2009-07-23 2009-07-23
US26207909P 2009-11-17 2009-11-17
US12/684,053 US20100173013A1 (en) 2009-01-08 2010-01-07 Treatment of neoplastic disorders using combination therapies
PCT/US2010/041244 WO2011011199A1 (en) 2009-07-23 2010-07-07 Combination therapies with ck2 modulators

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MX2012000949A true MX2012000949A (es) 2012-04-20

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WO2011060380A1 (en) * 2009-11-14 2011-05-19 The Regents Of The University Of California Pik3ca mutation status and sash1 expression predicts synergy between lapatinib and an akt inhibitor in her2 positive breast cancer
CA2880896C (en) 2012-06-26 2021-11-16 Del Mar Pharmaceuticals Methods for treating tyrosine-kinase-inhibitor-resistant malignancies in patients with genetic polymorphisms or ahi1 dysregulations or mutations employing dianhydrogalactitol, diacetyldianhydrogalactitol, dibromodulcitol, or analogs or derivatives thereof
CA3182876A1 (en) * 2012-11-21 2014-05-30 Janssen Biotech, Inc. Bispecific egfr/c-met antibodies
US11491154B2 (en) 2013-04-08 2022-11-08 Dennis M. Brown Therapeutic benefit of suboptimally administered chemical compounds
US10195153B2 (en) 2013-08-12 2019-02-05 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
US9492444B2 (en) 2013-12-17 2016-11-15 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
US10172797B2 (en) 2013-12-17 2019-01-08 Pharmaceutical Manufacturing Research Services, Inc. Extruded extended release abuse deterrent pill
DK3129037T3 (da) * 2014-04-10 2020-02-03 Transgene Onkolytiske koppevirusvektorer
JP6371463B2 (ja) 2014-07-17 2018-08-08 ファーマシューティカル マニュファクチュアリング リサーチ サービシズ，インコーポレーテッド 即時放出性乱用抑止性液体充填剤形
EP3209282A4 (en) 2014-10-20 2018-05-23 Pharmaceutical Manufacturing Research Services, Inc. Extended release abuse deterrent liquid fill dosage form
US10213449B2 (en) * 2016-06-16 2019-02-26 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for treating medulloblastoma
CA3116731A1 (en) * 2018-10-19 2020-04-23 Senhwa Biosciences, Inc. Combinations for immune-modulation in cancer treatment
CN112274642A (zh) * 2020-10-15 2021-01-29 北京大学人民医院 Ck2抑制剂在制备类风湿关节炎治疗药物中的应用

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US20040102360A1 (en) * 2002-10-30 2004-05-27 Barnett Stanley F. Combination therapy
CU23511B6 (es) * 2006-02-28 2010-04-13 Biorec B V Combinación farmacéutica para el tratamiento y/o quimiosensibilización de tumores refractarios a drogas anticancerígenas
PT2061765E (pt) * 2006-09-01 2015-02-06 Senhwa Biosciences Inc Moduladores de serina-treonina-proteína-quinase e de parp
US8828451B2 (en) * 2006-10-04 2014-09-09 University Of South Florida Akt sensitization of cancer cells
AU2008300026A1 (en) * 2007-09-11 2009-03-19 Merck Sharp & Dohme Corp. Inhibitors of Janus kinases
JP2011515337A (ja) * 2008-02-29 2011-05-19 サイレーン ファーマシューティカルズ， インコーポレイテッド プロテインキナーゼモジュレーター
EP2381942A1 (en) * 2009-01-08 2011-11-02 Cylene Pharmaceuticals, Inc. Combination therapies for neoplastic disorders

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CN102497862A (zh) 2012-06-13
WO2011011199A1 (en) 2011-01-27
KR20120089250A (ko) 2012-08-09
RU2012106518A (ru) 2013-08-27
BR112012001555A2 (pt) 2016-03-08
JP2012533624A (ja) 2012-12-27
US20100173013A1 (en) 2010-07-08
EP2456441A1 (en) 2012-05-30
AU2010274165A1 (en) 2012-03-15
SG177737A1 (en) 2012-02-28
CA2768631A1 (en) 2011-01-27
CN102497862B (zh) 2015-03-25

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