BR112012001555A2 - terapias de combinação com moduladores de ck2 - Google Patents
terapias de combinação com moduladores de ck2Info
- Publication number
- BR112012001555A2 BR112012001555A2 BR112012001555A BR112012001555A BR112012001555A2 BR 112012001555 A2 BR112012001555 A2 BR 112012001555A2 BR 112012001555 A BR112012001555 A BR 112012001555A BR 112012001555 A BR112012001555 A BR 112012001555A BR 112012001555 A2 BR112012001555 A2 BR 112012001555A2
- Authority
- BR
- Brazil
- Prior art keywords
- modulators
- combination therapies
- therapies
- combination
- Prior art date
Links
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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Applications Claiming Priority (4)
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US22812109P | 2009-07-23 | 2009-07-23 | |
US26207909P | 2009-11-17 | 2009-11-17 | |
US12/684,053 US20100173013A1 (en) | 2009-01-08 | 2010-01-07 | Treatment of neoplastic disorders using combination therapies |
PCT/US2010/041244 WO2011011199A1 (en) | 2009-07-23 | 2010-07-07 | Combination therapies with ck2 modulators |
Publications (1)
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BR112012001555A2 true BR112012001555A2 (pt) | 2016-03-08 |
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Family Applications (1)
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BR112012001555A BR112012001555A2 (pt) | 2009-07-23 | 2010-07-07 | terapias de combinação com moduladores de ck2 |
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US (1) | US20100173013A1 (pt) |
EP (1) | EP2456441A1 (pt) |
JP (1) | JP2012533624A (pt) |
KR (1) | KR20120089250A (pt) |
CN (1) | CN102497862B (pt) |
AU (1) | AU2010274165A1 (pt) |
BR (1) | BR112012001555A2 (pt) |
CA (1) | CA2768631A1 (pt) |
MX (1) | MX2012000949A (pt) |
RU (1) | RU2012106518A (pt) |
SG (1) | SG177737A1 (pt) |
WO (1) | WO2011011199A1 (pt) |
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WO2011060380A1 (en) * | 2009-11-14 | 2011-05-19 | The Regents Of The University Of California | Pik3ca mutation status and sash1 expression predicts synergy between lapatinib and an akt inhibitor in her2 positive breast cancer |
AU2013280644B2 (en) | 2012-06-26 | 2018-08-02 | Jeffrey A. BACHA | Methods for treating tyrosine-kinase-inhibitor-resistant malignancies in patients with genetic polymorphisms or AHI1 dysregulations or mutations employing dianhydrogalactitol, diacetyldianhydrogalactitol, dibromodulcitol, or analogs or derivatives thereof |
MX361088B (es) * | 2012-11-21 | 2018-11-26 | Janssen Biotech Inc | Anticuerpos del receptor del factor de crecimiento epidérmico aislado/del receptor del factor de crecimiento de hepatocitos (egfr/c-met) biespecíficos. |
JP2016519684A (ja) | 2013-04-08 | 2016-07-07 | デニス エム ブラウン | 準最適に投与された薬物療法の有効性を改善するための及び/又は副作用を低減するための方法および組成物 |
WO2015023675A2 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
CN106413726B (zh) * | 2014-04-10 | 2020-07-24 | 特朗斯吉有限公司 | 痘病毒溶瘤载体 |
WO2016010771A1 (en) | 2014-07-17 | 2016-01-21 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
JP2017531026A (ja) | 2014-10-20 | 2017-10-19 | ファーマシューティカル マニュファクチュアリング リサーチ サービシズ,インコーポレーテッド | 徐放性乱用抑止性液体充填剤形 |
US10213449B2 (en) * | 2016-06-16 | 2019-02-26 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for treating medulloblastoma |
WO2020081971A1 (en) * | 2018-10-19 | 2020-04-23 | Senhwa Biosciences, Inc. | Combinations for immune-modulation in cancer treatment |
CN112274642A (zh) * | 2020-10-15 | 2021-01-29 | 北京大学人民医院 | Ck2抑制剂在制备类风湿关节炎治疗药物中的应用 |
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US20040102360A1 (en) * | 2002-10-30 | 2004-05-27 | Barnett Stanley F. | Combination therapy |
CU23511B6 (es) * | 2006-02-28 | 2010-04-13 | Biorec B V | Combinación farmacéutica para el tratamiento y/o quimiosensibilización de tumores refractarios a drogas anticancerígenas |
DK2061765T3 (en) * | 2006-09-01 | 2015-01-26 | Senhwa Biosciences Inc | Serine-threonine protein kinase AND PARP-MODULATOR |
US8828451B2 (en) * | 2006-10-04 | 2014-09-09 | University Of South Florida | Akt sensitization of cancer cells |
WO2009035575A1 (en) * | 2007-09-11 | 2009-03-19 | Merck & Co., Inc. | Inhibitors of janus kinases |
AU2009219154A1 (en) * | 2008-02-29 | 2009-09-03 | Cylene Pharmaceuticals, Inc. | Protein kinase modulators |
RU2011133093A (ru) * | 2009-01-08 | 2013-02-20 | Сайлин Фармасьютикалс, Инк. | Комбинированная терапия неопластических заболеваний |
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2010
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- 2010-07-07 JP JP2012521665A patent/JP2012533624A/ja active Pending
- 2010-07-07 MX MX2012000949A patent/MX2012000949A/es not_active Application Discontinuation
- 2010-07-07 BR BR112012001555A patent/BR112012001555A2/pt not_active Application Discontinuation
- 2010-07-07 EP EP10734398A patent/EP2456441A1/en not_active Withdrawn
- 2010-07-07 SG SG2012004933A patent/SG177737A1/en unknown
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- 2010-07-07 WO PCT/US2010/041244 patent/WO2011011199A1/en active Application Filing
- 2010-07-07 CA CA2768631A patent/CA2768631A1/en not_active Abandoned
- 2010-07-07 AU AU2010274165A patent/AU2010274165A1/en not_active Abandoned
- 2010-07-07 RU RU2012106518/15A patent/RU2012106518A/ru unknown
Also Published As
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RU2012106518A (ru) | 2013-08-27 |
US20100173013A1 (en) | 2010-07-08 |
AU2010274165A1 (en) | 2012-03-15 |
SG177737A1 (en) | 2012-02-28 |
MX2012000949A (es) | 2012-04-20 |
JP2012533624A (ja) | 2012-12-27 |
KR20120089250A (ko) | 2012-08-09 |
CN102497862B (zh) | 2015-03-25 |
CN102497862A (zh) | 2012-06-13 |
CA2768631A1 (en) | 2011-01-27 |
WO2011011199A1 (en) | 2011-01-27 |
EP2456441A1 (en) | 2012-05-30 |
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