MX2012000431A - Procedimientos para 3-amino-5-oxo-4,5-dihidro-[1,2,4]triazinas sustituidas. - Google Patents
Procedimientos para 3-amino-5-oxo-4,5-dihidro-[1,2,4]triazinas sustituidas.Info
- Publication number
- MX2012000431A MX2012000431A MX2012000431A MX2012000431A MX2012000431A MX 2012000431 A MX2012000431 A MX 2012000431A MX 2012000431 A MX2012000431 A MX 2012000431A MX 2012000431 A MX2012000431 A MX 2012000431A MX 2012000431 A MX2012000431 A MX 2012000431A
- Authority
- MX
- Mexico
- Prior art keywords
- amino
- dihydro
- oxo
- triazine
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
Abstract
Procedimientos incluyendo la preparación de metil éster del ácido trans-4-[(3-amino-5-oxo-4,5-dihidro-[1,2,4]triazin-6-ilmetil)-car bamoil]-ciclohexanocarboxilico, y su conversión a compuestos del ácido trans-4-(4-amino-5-sustituido-imidazo[5,1-f][1,2,4]triazin-7 -il)-ciclohexanocarboxlico.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22409009P | 2009-07-09 | 2009-07-09 | |
PCT/US2010/041278 WO2011005909A2 (en) | 2009-07-09 | 2010-07-08 | Process for substituted 3-amino-5-oxo-4,5-dihydro-[1,2,4]triazines |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012000431A true MX2012000431A (es) | 2012-02-21 |
Family
ID=43429828
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012000431A MX2012000431A (es) | 2009-07-09 | 2010-07-08 | Procedimientos para 3-amino-5-oxo-4,5-dihidro-[1,2,4]triazinas sustituidas. |
Country Status (9)
Country | Link |
---|---|
US (1) | US20120108812A1 (es) |
EP (1) | EP2451792A4 (es) |
JP (1) | JP2012532882A (es) |
KR (1) | KR20120047256A (es) |
CN (1) | CN102471292A (es) |
BR (1) | BR112012000494A2 (es) |
CA (1) | CA2764173A1 (es) |
MX (1) | MX2012000431A (es) |
WO (1) | WO2011005909A2 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY148491A (en) | 2005-11-17 | 2013-04-30 | Osi Pharm Inc | FUSED BICYCLIC mTOR INHIBITORS |
EA018144B1 (ru) | 2008-03-19 | 2013-05-30 | Оси Фармасьютикалз, Инк. | СОЛЕВЫЕ ФОРМЫ ИНГИБИТОРА mTOR |
KR101548443B1 (ko) | 2011-02-23 | 2015-08-28 | 화이자 인코포레이티드 | 신경 장애의 치료를 위한 이미다조[5,1-f][1,2,4]트라이아진 |
WO2023229605A1 (en) * | 2022-05-27 | 2023-11-30 | Avalo Therapeutics, Inc. | Methods and treatment for complex lymphatic malformations |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY148491A (en) * | 2005-11-17 | 2013-04-30 | Osi Pharm Inc | FUSED BICYCLIC mTOR INHIBITORS |
EP1996193A2 (en) * | 2006-03-13 | 2008-12-03 | OSI Pharmaceuticals, Inc. | Combined treatment with an egfr kinase inhibitor and an agent that sensitizes tumor cells to the effects of egfr kinase inhibitors |
EP2178563A2 (en) * | 2007-07-06 | 2010-04-28 | OSI Pharmaceuticals, Inc. | Combination anti-cancer therapy comprising an inhibitor of both mtorc1 and mtorc2 |
-
2010
- 2010-07-08 BR BR112012000494A patent/BR112012000494A2/pt not_active IP Right Cessation
- 2010-07-08 US US13/383,035 patent/US20120108812A1/en not_active Abandoned
- 2010-07-08 MX MX2012000431A patent/MX2012000431A/es not_active Application Discontinuation
- 2010-07-08 JP JP2012519707A patent/JP2012532882A/ja active Pending
- 2010-07-08 EP EP10797821A patent/EP2451792A4/en not_active Withdrawn
- 2010-07-08 KR KR1020127003400A patent/KR20120047256A/ko not_active Application Discontinuation
- 2010-07-08 CN CN2010800302336A patent/CN102471292A/zh active Pending
- 2010-07-08 CA CA2764173A patent/CA2764173A1/en not_active Abandoned
- 2010-07-08 WO PCT/US2010/041278 patent/WO2011005909A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
KR20120047256A (ko) | 2012-05-11 |
US20120108812A1 (en) | 2012-05-03 |
CA2764173A1 (en) | 2011-01-13 |
CN102471292A (zh) | 2012-05-23 |
JP2012532882A (ja) | 2012-12-20 |
EP2451792A2 (en) | 2012-05-16 |
EP2451792A4 (en) | 2013-03-06 |
BR112012000494A2 (pt) | 2015-09-15 |
WO2011005909A3 (en) | 2011-05-12 |
WO2011005909A2 (en) | 2011-01-13 |
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Legal Events
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FA | Abandonment or withdrawal |