MX2010005932A - Metodos y composiciones para mejorar la viabilidad de poros de microaguja. - Google Patents
Metodos y composiciones para mejorar la viabilidad de poros de microaguja.Info
- Publication number
- MX2010005932A MX2010005932A MX2010005932A MX2010005932A MX2010005932A MX 2010005932 A MX2010005932 A MX 2010005932A MX 2010005932 A MX2010005932 A MX 2010005932A MX 2010005932 A MX2010005932 A MX 2010005932A MX 2010005932 A MX2010005932 A MX 2010005932A
- Authority
- MX
- Mexico
- Prior art keywords
- compositons
- viability
- enhancing
- methods
- microneedle
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Aquí se describe un método para administrar transdérmicamente uno o más agentes farmacéuticamente activos a un mamífero. El método comprende administrar uno o más agentes farmacéuticos activos a la piel del sujeto, junto con microagujas y uno o más inhibidores COX, con lo cual los inhibidores COX facilitan la absorción de los agentes farmacéuticos activos al prolongar la abertura de poro creada por la aplicación de la microaguja.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99097207P | 2007-11-29 | 2007-11-29 | |
PCT/US2008/085195 WO2009073630A2 (en) | 2007-11-29 | 2008-12-01 | Methods and compositons for enhancing the viability of microneedle pores |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010005932A true MX2010005932A (es) | 2010-06-15 |
Family
ID=40676499
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010005932A MX2010005932A (es) | 2007-11-29 | 2008-12-01 | Metodos y composiciones para mejorar la viabilidad de poros de microaguja. |
Country Status (7)
Country | Link |
---|---|
US (4) | US20090143762A1 (es) |
EP (2) | EP2478893B8 (es) |
JP (1) | JP5563473B2 (es) |
AT (1) | ATE542521T1 (es) |
CA (1) | CA2705131C (es) |
MX (1) | MX2010005932A (es) |
WO (1) | WO2009073630A2 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9566341B1 (en) | 2011-04-27 | 2017-02-14 | University Of Kentucky Research Foundation | Compounds including Cox inhibitor moiety and enhanced delivery of active drugs using same |
WO2012151427A1 (en) * | 2011-05-03 | 2012-11-08 | Aponia Laboratories, Inc. | Transdermal compositions of ibuprofen and methods of use thereof |
SG11201405643RA (en) * | 2012-03-16 | 2014-10-30 | Univ Singapore | A novel method to fabricate polymeric microneedles |
US20140134124A1 (en) * | 2012-11-13 | 2014-05-15 | Donna Lynn Huff | Sanitary compound for use on skin |
EP3034115A1 (en) * | 2014-12-19 | 2016-06-22 | Sanofi-Aventis Deutschland GmbH | Needle interface |
CN109415431A (zh) * | 2016-04-20 | 2019-03-01 | 爱兰细胞技术公司 | 与k180二甲基化h1.0蛋白相关的组合物和方法 |
JP7183041B2 (ja) * | 2016-06-29 | 2022-12-05 | センジュ ユーエスエー、インコーポレイテッド | 経皮薬物送達システムおよびその使用方法 |
KR102042456B1 (ko) * | 2018-03-22 | 2019-11-08 | 크리스탈지노믹스(주) | 경피흡수제제 |
CN109528695B (zh) * | 2019-01-12 | 2022-04-19 | 蚌埠医学院 | 一种治疗类风湿性关节炎的微针透皮给药贴片及其制备方法 |
US20220378729A1 (en) * | 2019-11-06 | 2022-12-01 | Smartech Topical, Inc. | Topical formulations of cyclooxygenase inhibitors and their use |
TWI730504B (zh) * | 2019-11-19 | 2021-06-11 | 奇異平台股份有限公司 | 經皮微針監測系統 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1860432A (en) | 1928-08-22 | 1932-05-31 | Brown Co | Process of lowering the solution viscosity of cellulose fiber |
US20030203956A1 (en) * | 1998-12-23 | 2003-10-30 | Masterrer Jaime L. | Method of using a cyclooxygenase-2 inhibitor and one or more ornithine decarboxylase inhibitors as a combination therapy in the treatment of neoplasia |
US20020076452A1 (en) * | 2000-08-01 | 2002-06-20 | Ashni Naturaceuticals, Inc. | Combinations of sesquiterpene lactones and ditepene lactones or triterpenes for synergistic inhibition of cyclooxygenase-2 |
DE10060852A1 (de) * | 2000-12-06 | 2002-06-20 | Hexal Ag | Absorptionsmittel und Kanalbildner enthaltende wirkstoffundurchlässige Deckschicht oder abziehbare Schutzschicht eines transdermalen therapeutischen Systems |
US20020111377A1 (en) | 2000-12-22 | 2002-08-15 | Albany College Of Pharmacy | Transdermal delivery of cannabinoids |
US7695736B2 (en) * | 2001-04-03 | 2010-04-13 | Pfizer Inc. | Reconstitutable parenteral composition |
US20030073609A1 (en) * | 2001-06-29 | 2003-04-17 | Pinkerton Thomas C. | Enhanced pharmacokinetic profile of intradermally delivered substances |
DE10161077A1 (de) * | 2001-12-12 | 2003-06-18 | Boehringer Ingelheim Vetmed | Hochkonzentrierte stabile Meloxicamlösungen zur nadellosen Injektion |
US20030129208A1 (en) * | 2002-01-07 | 2003-07-10 | Alberts David S. | Topical application of alpha-DFMO and anti-inflammatory drug for treatment of actinic keratoses |
US20080051373A1 (en) * | 2003-07-31 | 2008-02-28 | The Board Of Regents Of The University Of Texas System | Parenteral preparations of GI-safer phospholipid-associated anti-inflammatories and methods of preparation and use |
US20050137164A1 (en) * | 2003-09-22 | 2005-06-23 | Moshe Arkin | Diclofenac compositions for the treatment of skin disorders |
MXPA06006041A (es) * | 2003-11-28 | 2007-01-31 | Acrux Dds Pty Ltd | Metodo y sistema para administracion transdermica rapida. |
US20050220862A1 (en) * | 2004-03-31 | 2005-10-06 | Bernstein Joel E | Compositions with reduced hepatotoxicity |
US7627938B2 (en) * | 2004-10-15 | 2009-12-08 | Board Of Regents, The Univeristy Of Texas System | Tapered hollow metallic microneedle array assembly and method of making and using the same |
KR20070059154A (ko) * | 2004-11-22 | 2007-06-11 | 비너스 레머디스 리미티드 | 비수계의 액상 비경구 아세클로페낙 제제 |
US20080008745A1 (en) | 2006-06-21 | 2008-01-10 | University Of Kentucky Research Foundation | Transdermal delivery of naltrexone hydrochloride, naltrexol hydrochloride, and bis(hydroxy-methyl)propionyl-3-0 ester naltrexone using microneedles |
EP2068833B1 (en) * | 2006-07-26 | 2013-01-09 | The Board of Regents of the University of Texas System | Parenteral preparations of gi-safer phospholipid-associated anti-inflammatories and methods of preparation and use |
CA2663515C (en) | 2006-09-22 | 2015-09-01 | Alltranz Inc. | Transdermally deliverable buprenorphine prodrugs and abuse-resistant compositions thereof |
-
2008
- 2008-12-01 MX MX2010005932A patent/MX2010005932A/es unknown
- 2008-12-01 EP EP12152270.0A patent/EP2478893B8/en not_active Not-in-force
- 2008-12-01 JP JP2010536227A patent/JP5563473B2/ja not_active Expired - Fee Related
- 2008-12-01 EP EP08856085A patent/EP2222274B1/en not_active Not-in-force
- 2008-12-01 CA CA2705131A patent/CA2705131C/en not_active Expired - Fee Related
- 2008-12-01 AT AT08856085T patent/ATE542521T1/de active
- 2008-12-01 US US12/325,919 patent/US20090143762A1/en not_active Abandoned
- 2008-12-01 WO PCT/US2008/085195 patent/WO2009073630A2/en active Application Filing
-
2014
- 2014-09-10 US US14/482,850 patent/US20150182453A1/en not_active Abandoned
-
2018
- 2018-08-23 US US16/110,665 patent/US20190054014A1/en not_active Abandoned
-
2021
- 2021-04-13 US US17/228,941 patent/US20220117884A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2705131A1 (en) | 2009-06-11 |
ATE542521T1 (de) | 2012-02-15 |
WO2009073630A2 (en) | 2009-06-11 |
US20150182453A1 (en) | 2015-07-02 |
EP2478893B1 (en) | 2013-08-21 |
JP5563473B2 (ja) | 2014-07-30 |
EP2222274A2 (en) | 2010-09-01 |
EP2222274B1 (en) | 2012-01-25 |
JP2011505380A (ja) | 2011-02-24 |
US20190054014A1 (en) | 2019-02-21 |
WO2009073630A4 (en) | 2010-04-01 |
CA2705131C (en) | 2016-06-28 |
EP2478893B8 (en) | 2013-10-09 |
US20220117884A1 (en) | 2022-04-21 |
EP2478893A1 (en) | 2012-07-25 |
WO2009073630A3 (en) | 2010-02-04 |
US20090143762A1 (en) | 2009-06-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2010005932A (es) | Metodos y composiciones para mejorar la viabilidad de poros de microaguja. | |
ATE489048T1 (de) | Vorrichtung für kombinierte behandlung | |
WO2010091376A3 (en) | Devices and methods for perfusion therapy | |
DK3248600T3 (da) | Kombinationer og måder til administration af terapeutiske stoffer og kombinationsterapi | |
UA122324C2 (uk) | Терапевтично активні сполуки і способи їх застосування | |
AR055552A1 (es) | Preparacion topica refrescante para parches y metodos para utilizar la misma | |
NZ611920A (en) | Percutaneous absorption preparation containing rivastigmine | |
CO6300964A2 (es) | Una composicion farmaceutica que comprende una combinacion de un agente quimioterapeutico y un anticuerpo 3 antiglipicano | |
EA201001402A1 (ru) | Фармацевтические растворы, способ получения и терапевтическое применение | |
UY30158A1 (es) | Uso de derivados de benzo-heteroaril sulfamida para el tratamiento del dolor | |
PE20081874A1 (es) | Composicion farmaceutica que comprende buprenorfina y naloxona | |
IN2012DN01225A (es) | ||
MX2019008817A (es) | Formulacion de liberacion prolongada para reducir la frecuencia de miccion y metodo de uso de la misma. | |
PE20121538A1 (es) | Combinaciones terapeuticas de teobromina y una antihistamina | |
MX2009011900A (es) | Curacion de herida diabetica. | |
MX348418B (es) | Composicion ocular que contiene bromfenaco con biodisponibilidad incrementada. | |
BR112012015437A2 (pt) | composição tópica substancialmente anidra de armazenamento estável | |
DK2124640T3 (da) | Glucoseisomerase til anvendelse i behandlingen af fruktoseintolerans | |
ATE510594T1 (de) | Hustenpräparat | |
PE20121537A1 (es) | Combinacion de teobromina con un descongestivo | |
MX2014001823A (es) | Combinaciones de corroles y estatinas. | |
MX2007001206A (es) | Metodos para tratar la piel para mejorar el tratamiento terapeutico de la misma. | |
CL2011000614A1 (es) | Forma de dosificacion oral solida que comprende alisquireno solo o en combinacion con otro agente activo; proceso de preparacion; y uso en el tratamiento de enfermedades tales comohipertension, angina, ateroesclerosis, entre otras. | |
PE20120515A1 (es) | Formulaciones de deferiprona | |
CL2015003145A1 (es) | Nuevo uso de clorhidrato de landiolol en el tratamiento a largo plazo de taquiarritmias |