MX348418B - Composicion ocular que contiene bromfenaco con biodisponibilidad incrementada. - Google Patents

Composicion ocular que contiene bromfenaco con biodisponibilidad incrementada.

Info

Publication number
MX348418B
MX348418B MX2014004347A MX2014004347A MX348418B MX 348418 B MX348418 B MX 348418B MX 2014004347 A MX2014004347 A MX 2014004347A MX 2014004347 A MX2014004347 A MX 2014004347A MX 348418 B MX348418 B MX 348418B
Authority
MX
Mexico
Prior art keywords
composition containing
bromfenac
increased bioavailability
ocular composition
containing bromfenac
Prior art date
Application number
MX2014004347A
Other languages
English (en)
Other versions
MX2014004347A (es
Inventor
Padilla Angel
Baklayan George
Original Assignee
Bausch & Lomb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47073541&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX348418(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bausch & Lomb filed Critical Bausch & Lomb
Publication of MX2014004347A publication Critical patent/MX2014004347A/es
Publication of MX348418B publication Critical patent/MX348418B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/775—Phenolic resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describen las formulaciones y métodos que proporcionan penetración mejorada del bromfenaco dentro del tejido ocular cuando se administran tópicamente, en comparación a la formulación BROMDAYMR y el método actualmente disponibles, cuando se administra tópicamente. Las formulaciones y los métodos lo hicieron así mientras conservaron la conveniencia del paciente de una administración vez al día y disminuyeron ventajosamente la concentración del bromfenaco dosificado al paciente.
MX2014004347A 2011-10-12 2012-10-11 Composicion ocular que contiene bromfenaco con biodisponibilidad incrementada. MX348418B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161546290P 2011-10-12 2011-10-12
PCT/US2012/059653 WO2013055856A1 (en) 2011-10-12 2012-10-11 Ocular composition containing bromfenac with increased bioavailability

Publications (2)

Publication Number Publication Date
MX2014004347A MX2014004347A (es) 2014-07-28
MX348418B true MX348418B (es) 2017-06-12

Family

ID=47073541

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014004347A MX348418B (es) 2011-10-12 2012-10-11 Composicion ocular que contiene bromfenaco con biodisponibilidad incrementada.

Country Status (5)

Country Link
US (3) US9517220B2 (es)
EP (1) EP2765988B1 (es)
CA (1) CA2852995C (es)
MX (1) MX348418B (es)
WO (1) WO2013055856A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004013420T2 (de) * 2003-01-21 2009-06-04 Senju Pharmaceutical Co., Ltd. Wässrige flüssige zubereitung mit 2-amino-3-(4-bromobenzoyl)phenylessigsäure
US8778999B2 (en) * 2009-03-05 2014-07-15 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic compositions
WO2014204952A1 (en) 2013-06-19 2014-12-24 Sentiss Research Center Stable bromfenac solution
WO2015087267A2 (en) 2013-12-12 2015-06-18 Sentiss Pharma Private Limited Stable bromfenac ophthalmic solution
ES2538551B1 (es) 2013-12-20 2016-01-13 Eurocanarias Oftalmológica, Sl Composición Oftálmica para la corrección de la presbicia
CN104151182B (zh) * 2014-06-16 2016-03-30 广东众生药业股份有限公司 一种溴芬酸钠倍半水合物的制备方法
IT202000002296A1 (it) * 2020-02-06 2021-08-06 Sifi Spa Formulazioni topiche oftalmiche a base di xantano con ridotta posologia

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5558876A (en) * 1995-03-29 1996-09-24 Alcon Laboratories, Inc. Topical ophthalmic acidic drug formulations
US5942508A (en) 1997-02-04 1999-08-24 Senju Pharmaceutical Co., Ltd. Method for solubilizing pyridonecarboxylic acid solubilizer thereof and aqueous solution containing solubilized pyridonecarboxylic acid
US6552020B1 (en) 1999-07-30 2003-04-22 Allergan, Inc. Compositions including antibiotics and methods for using same
DE602004013420T2 (de) 2003-01-21 2009-06-04 Senju Pharmaceutical Co., Ltd. Wässrige flüssige zubereitung mit 2-amino-3-(4-bromobenzoyl)phenylessigsäure
US20070299124A1 (en) 2006-01-25 2007-12-27 Ousler George W Iii Formulations and methods for treating dry eye
US20080039398A1 (en) * 2006-01-25 2008-02-14 Ousler George W Iii Formulations and methods for treating dry eye
US20070297981A1 (en) * 2006-01-25 2007-12-27 Ousler George W Iii Formulations and methods for treating dry eye
JP2011513229A (ja) 2008-02-21 2011-04-28 イスタ・ファーマスーティカルズ・インコーポレイテッド 補助剤としての眼科用ｎｓａｉｄ
US20100008993A1 (en) 2008-07-14 2010-01-14 Proksch Joel W Compositions and Methods for Increasing Bioavailability of Topical Ophthalmic Drugs
US8778999B2 (en) * 2009-03-05 2014-07-15 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic compositions
EP2498768A1 (en) 2009-11-11 2012-09-19 Micro Labs Limited Pharmaceutical combination of prostaglandin compound and nsaid for the treatment of glaucoma and ocular hypertension
SI2555770T1 (en) 2010-04-09 2018-04-30 Allergan, Inc. Creation of ketorolac for the treatment of corneal damage

Also Published As

Publication number Publication date
US20130096199A1 (en) 2013-04-18
WO2013055856A1 (en) 2013-04-18
US10085958B2 (en) 2018-10-02
MX2014004347A (es) 2014-07-28
CA2852995A1 (en) 2013-04-18
CA2852995C (en) 2016-03-29
US20180353451A1 (en) 2018-12-13
US9517220B2 (en) 2016-12-13
EP2765988A1 (en) 2014-08-20
EP2765988B1 (en) 2024-09-18
US20170049735A1 (en) 2017-02-23

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