MX2010004620A - Derivados de benzomorfolina y metodos de uso. - Google Patents
Derivados de benzomorfolina y metodos de uso.Info
- Publication number
- MX2010004620A MX2010004620A MX2010004620A MX2010004620A MX2010004620A MX 2010004620 A MX2010004620 A MX 2010004620A MX 2010004620 A MX2010004620 A MX 2010004620A MX 2010004620 A MX2010004620 A MX 2010004620A MX 2010004620 A MX2010004620 A MX 2010004620A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- diseases
- compounds
- prophylaxis
- processes
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- YRLORWPBJZEGBX-UHFFFAOYSA-N 3,4-dihydro-2h-1,4-benzoxazine Chemical class C1=CC=C2NCCOC2=C1 YRLORWPBJZEGBX-UHFFFAOYSA-N 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000011321 prophylaxis Methods 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 abstract 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94807P | 2007-10-29 | 2007-10-29 | |
| PCT/US2008/012224 WO2009058267A2 (en) | 2007-10-29 | 2008-10-28 | Benzomorpholine derivatives and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010004620A true MX2010004620A (es) | 2010-07-28 |
Family
ID=40394086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010004620A MX2010004620A (es) | 2007-10-29 | 2008-10-28 | Derivados de benzomorfolina y metodos de uso. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7795254B2 (enExample) |
| EP (1) | EP2220078B1 (enExample) |
| JP (1) | JP5343082B2 (enExample) |
| AU (1) | AU2008319366B2 (enExample) |
| CA (1) | CA2703257C (enExample) |
| ES (1) | ES2417009T3 (enExample) |
| MX (1) | MX2010004620A (enExample) |
| WO (1) | WO2009058267A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH684182A5 (de) | 1991-10-15 | 1994-07-29 | Escher Wyss Ag | Rotationsdruckmaschine. |
| US9206146B2 (en) | 2010-05-19 | 2015-12-08 | Sandoz Ag | Purification of posaconazole and of posaconazole intermediates |
| RU2580318C2 (ru) * | 2010-05-19 | 2016-04-10 | Сандоз Аг | Получение промежуточных продуктов для синтеза позаконазола |
| US9199919B2 (en) | 2010-05-19 | 2015-12-01 | Sandoz Ag | Process for the preparation of chiral hydrazides |
| CN108329303A (zh) | 2011-06-16 | 2018-07-27 | 桑多斯股份公司 | 制备手性化合物的方法 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3755332A (en) | 1971-07-01 | 1973-08-28 | Ciba Geigy Corp | Substituted 4 indazolaminoquinolines |
| US4916135A (en) | 1989-05-08 | 1990-04-10 | Hoechst Roussel Pharmaceuticals Inc. | N-heteroaryl-4-quinolinamines |
| GB9323290D0 (en) | 1992-12-10 | 1994-01-05 | Zeneca Ltd | Quinazoline derivatives |
| WO1996023774A1 (en) | 1995-01-31 | 1996-08-08 | Zenyaku Kogyo Kabushiki Kaisha | Thioquinoline derivatives |
| GB9505702D0 (en) | 1995-03-21 | 1995-05-10 | Agrevo Uk Ltd | Fungicidal compounds |
| GB9505651D0 (en) | 1995-03-21 | 1995-05-10 | Agrevo Uk Ltd | AgrEvo UK Limited |
| GB9514265D0 (en) | 1995-07-13 | 1995-09-13 | Wellcome Found | Hetrocyclic compounds |
| WO1997017329A1 (en) | 1995-11-07 | 1997-05-15 | Kirin Beer Kabushiki Kaisha | Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same |
| JPH10512896A (ja) | 1995-11-14 | 1998-12-08 | フアルマシア・エ・アツプジヨン・エツセ・ピー・アー | アリールおよびヘテロアリールプリン化合物 |
| GB9603095D0 (en) | 1996-02-14 | 1996-04-10 | Zeneca Ltd | Quinazoline derivatives |
| DE19614718A1 (de) | 1996-04-15 | 1997-10-16 | Hoechst Schering Agrevo Gmbh | Substituierte Pyridine/Pyrimidine, Verfahren zu ihrer Herstellung, und ihre Verwendung als Schädlingsbekämpfungsmittel |
| GB9800575D0 (en) | 1998-01-12 | 1998-03-11 | Glaxo Group Ltd | Heterocyclic compounds |
| ATE293102T1 (de) | 1998-04-23 | 2005-04-15 | Takeda Pharmaceutical | Naphthalene derivate ,ihre herstellung und verwendung |
| EP1105378B1 (en) | 1998-08-21 | 2005-03-30 | Parker Hughes Institute | Quinazoline derivatives |
| BRPI0017548B8 (pt) | 1999-02-10 | 2023-05-02 | Astrazeneca Ab | Composto |
| US6258820B1 (en) | 1999-03-19 | 2001-07-10 | Parker Hughes Institute | Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines |
| EE200100528A (et) | 1999-04-12 | 2003-02-17 | Aventis Pharma Limited | Asendatud bitsükliline heteroarüülühend, seda sisaldav farmatseutiline kompositsioon ning nende raviotstarbeline kasutamine |
| AU2001292138A1 (en) | 2000-10-13 | 2002-04-22 | Astrazeneca Ab | Quinazoline derivatives with anti-tumour activity |
| EP1415987B1 (en) | 2000-10-20 | 2007-02-28 | Eisai R&D Management Co., Ltd. | Nitrogenous aromatic ring compounds as anti cancer agents |
| CA2454538A1 (en) | 2001-06-22 | 2003-01-03 | Kirin Beer Kabushiki Kaisha | Quinoline derivatives and quinazoline derivatives capable of inhibiting autophosphorylation of hepatocyte growth factor receptors, and pharmaceutical composition comprising the same |
| JP2005515176A (ja) | 2001-11-03 | 2005-05-26 | アストラゼネカ アクチボラグ | 抗腫瘍剤としてのキナゾリン誘導体 |
| GB0126433D0 (en) | 2001-11-03 | 2002-01-02 | Astrazeneca Ab | Compounds |
| CN1625555A (zh) | 2002-02-01 | 2005-06-08 | 阿斯特拉曾尼卡有限公司 | 喹唑啉化合物 |
| US7645878B2 (en) | 2002-03-22 | 2010-01-12 | Bayer Healthcare Llc | Process for preparing quinazoline Rho-kinase inhibitors and intermediates thereof |
| ATE447404T1 (de) | 2002-03-29 | 2009-11-15 | Novartis Vaccines & Diagnostic | Substituierte benzazole und ihre verwendung als raf-kinase-hemmer |
| CN1688549A (zh) | 2002-08-23 | 2005-10-26 | 麒麟麦酒株式会社 | 具有TGFβ抑制活性的化合物和含所述化合物的药用组合物 |
| US7320989B2 (en) | 2003-02-28 | 2008-01-22 | Encysive Pharmaceuticals, Inc. | Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists |
| WO2004078114A2 (en) | 2003-02-28 | 2004-09-16 | Encysive Pharmaceuticals Inc. | Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-ii receptor antagonists. |
| US7531553B2 (en) | 2003-03-21 | 2009-05-12 | Amgen Inc. | Heterocyclic compounds and methods of use |
| GB0310401D0 (en) | 2003-05-07 | 2003-06-11 | Astrazeneca Ab | Therapeutic agent |
| US7312330B2 (en) | 2003-12-24 | 2007-12-25 | Renovis, Inc. | Bicycloheteroarylamine compounds as ion channel ligands and uses thereof |
| JP4932495B2 (ja) * | 2004-01-23 | 2012-05-16 | アムゲン インコーポレイテッド | 化合物及び使用方法 |
| JO2787B1 (en) | 2005-04-27 | 2014-03-15 | امجين إنك, | Alternative amide derivatives and methods of use |
-
2008
- 2008-10-28 EP EP08845711.4A patent/EP2220078B1/en active Active
- 2008-10-28 US US12/290,223 patent/US7795254B2/en not_active Expired - Fee Related
- 2008-10-28 WO PCT/US2008/012224 patent/WO2009058267A2/en not_active Ceased
- 2008-10-28 AU AU2008319366A patent/AU2008319366B2/en not_active Ceased
- 2008-10-28 ES ES08845711T patent/ES2417009T3/es active Active
- 2008-10-28 JP JP2010532037A patent/JP5343082B2/ja not_active Expired - Fee Related
- 2008-10-28 CA CA2703257A patent/CA2703257C/en not_active Expired - Fee Related
- 2008-10-28 MX MX2010004620A patent/MX2010004620A/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ES2417009T3 (es) | 2013-08-05 |
| AU2008319366A1 (en) | 2009-05-07 |
| WO2009058267A2 (en) | 2009-05-07 |
| WO2009058267A3 (en) | 2010-06-10 |
| EP2220078A2 (en) | 2010-08-25 |
| US20090149454A1 (en) | 2009-06-11 |
| AU2008319366B2 (en) | 2012-03-01 |
| JP2011502147A (ja) | 2011-01-20 |
| EP2220078B1 (en) | 2013-05-22 |
| CA2703257C (en) | 2013-02-19 |
| CA2703257A1 (en) | 2009-05-07 |
| US7795254B2 (en) | 2010-09-14 |
| JP5343082B2 (ja) | 2013-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |