MX2010002409A - Composiciones y metodos para la distribucion de farmacos escasamente solubles. - Google Patents
Composiciones y metodos para la distribucion de farmacos escasamente solubles.Info
- Publication number
- MX2010002409A MX2010002409A MX2010002409A MX2010002409A MX2010002409A MX 2010002409 A MX2010002409 A MX 2010002409A MX 2010002409 A MX2010002409 A MX 2010002409A MX 2010002409 A MX2010002409 A MX 2010002409A MX 2010002409 A MX2010002409 A MX 2010002409A
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- poorly soluble
- soluble drugs
- delivery
- encapsulated
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96967207P | 2007-09-03 | 2007-09-03 | |
| PCT/US2008/010318 WO2009032246A2 (en) | 2007-09-03 | 2008-09-02 | Particulate compositions for delivery of poorly soluble drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010002409A true MX2010002409A (es) | 2010-05-19 |
Family
ID=40377549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010002409A MX2010002409A (es) | 2007-09-03 | 2008-09-02 | Composiciones y metodos para la distribucion de farmacos escasamente solubles. |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US8377479B2 (enExample) |
| EP (2) | EP3064198A1 (enExample) |
| JP (1) | JP2010537989A (enExample) |
| KR (1) | KR101545874B1 (enExample) |
| AU (1) | AU2008296971B2 (enExample) |
| CA (1) | CA2699172C (enExample) |
| DK (1) | DK2197429T3 (enExample) |
| ES (1) | ES2572157T3 (enExample) |
| HK (1) | HK1226306A1 (enExample) |
| HU (1) | HUE027537T2 (enExample) |
| MX (1) | MX2010002409A (enExample) |
| PL (1) | PL2197429T3 (enExample) |
| SI (1) | SI2197429T1 (enExample) |
| WO (1) | WO2009032246A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2939696E (pt) * | 2001-10-18 | 2016-06-17 | Nektar Therapeutics | Conjugados poliméricos de antagonistas de opióides |
| US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
| CA2687979C (en) | 2007-05-25 | 2017-07-04 | Tolmar Therapeutics, Inc. | Sustained delivery formulations of risperidone compounds |
| PL2197429T3 (pl) * | 2007-09-03 | 2016-09-30 | Kompozycje w postaci cząstek do dostarczania słabo rozpuszczalnych leków | |
| AU2010206724A1 (en) * | 2009-01-22 | 2011-07-28 | Nanotherapeutics, Inc. | Process for preparing particles of opioids and compositions produced thereby |
| US20100273730A1 (en) * | 2009-04-27 | 2010-10-28 | Innopharmax, Inc. | Self-emulsifying pharmaceutical compositions of hydrophilic drugs and preparation thereof |
| US9125867B2 (en) * | 2010-02-24 | 2015-09-08 | Invincible Biotechnology | Diversion- and/or abuse-resistant compositions and methods for making the same |
| GB2481017B (en) * | 2010-06-08 | 2015-01-07 | Rb Pharmaceuticals Ltd | Microparticle buprenorphine suspension |
| US9272044B2 (en) | 2010-06-08 | 2016-03-01 | Indivior Uk Limited | Injectable flowable composition buprenorphine |
| WO2012054831A2 (en) | 2010-10-21 | 2012-04-26 | Rtu Pharmaceuticals, Llc | Ready to use ketorolac formulations |
| CA2919892C (en) | 2013-08-12 | 2019-06-18 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| GB201404139D0 (en) | 2014-03-10 | 2014-04-23 | Rb Pharmaceuticals Ltd | Sustained release buprenorphine solution formulations |
| DK3169315T3 (da) | 2014-07-17 | 2020-08-10 | Pharmaceutical Manufacturing Res Services In | Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse |
| EP3209282A4 (en) | 2014-10-20 | 2018-05-23 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| WO2016071756A1 (en) | 2014-11-04 | 2016-05-12 | Innopharmax, Inc. | Oral administration of unstable or poorly-absorbed drugs |
| AU2015341490C1 (en) | 2014-11-07 | 2021-03-11 | Indivior Uk Limited | Buprenorphine dosing regimens |
| US10646484B2 (en) | 2017-06-16 | 2020-05-12 | Indivior Uk Limited | Methods to treat opioid use disorder |
| WO2019064026A1 (en) | 2017-09-29 | 2019-04-04 | Orexo Ab | NEW PHARMACEUTICAL COMPOSITIONS |
| IL273627B2 (en) | 2017-12-20 | 2025-03-01 | Purdue Pharma Lp | Morphine sulfate dosage forms for abuse deterrence |
| GB201904767D0 (en) | 2019-04-04 | 2019-05-22 | Orexo Ab | New pharmaceutical compositions |
| WO2021163252A1 (en) | 2020-02-14 | 2021-08-19 | Teikoku Pharma Usa, Inc. | Topical naloxone compositions and methods for using the same |
| GB202019335D0 (en) * | 2020-12-08 | 2021-01-20 | Artelo Biosciences Ltd | Pharmaceutical compositions |
| WO2024253935A1 (en) | 2023-06-05 | 2024-12-12 | Nanopharmaceutics, Inc. | Compositions and methods for oral delivery of sustained release crystalline prx-3140 |
Family Cites Families (62)
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| CA987588A (en) * | 1970-01-02 | 1976-04-20 | Sidney Riegelman | Solid dispersions of drugs |
| DE2400819C2 (de) * | 1974-01-09 | 1982-04-22 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung fester Zubereitungen von schwerlöslichen Arzneimittelwirkstoffen in feinster Verteilung |
| US4722941A (en) | 1978-06-07 | 1988-02-02 | Kali-Chemie Pharma Gmbh | Readily absorbable pharmaceutical compositions of per se poorly absorbable pharmacologically active agents and preparation thereof |
| ATE5852T1 (de) * | 1978-11-20 | 1984-02-15 | American Home Products Corporation | Therapeutische zusammensetzungen mit gesteigerter bioverfuegbarkeit und verfahren zu deren herstellung. |
| US4525339A (en) | 1982-10-15 | 1985-06-25 | Hoffmann-La Roche Inc. | Enteric coated oral dosage form |
| JPS6163614A (ja) * | 1984-09-04 | 1986-04-01 | Yamanouchi Pharmaceut Co Ltd | 難溶性薬物の溶解速度向上方法 |
| GB8514665D0 (en) * | 1985-06-11 | 1985-07-10 | Eroceltique Sa | Oral pharmaceutical composition |
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| WO1991014423A1 (fr) * | 1990-03-20 | 1991-10-03 | Otsuka Pharmaceutical Co., Ltd. | Preparation a base de liposomes |
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| FR2735658B1 (fr) * | 1995-06-21 | 1997-09-12 | Capsulis | Encapsulation de composes a usage alimentaire par des tensioactifs |
| US5681585A (en) | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
| US6235313B1 (en) | 1992-04-24 | 2001-05-22 | Brown University Research Foundation | Bioadhesive microspheres and their use as drug delivery and imaging systems |
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| US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
| US6368586B1 (en) | 1996-01-26 | 2002-04-09 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers |
| PT914097E (pt) * | 1996-03-12 | 2002-06-28 | Alza Corp | Composicao e forma de dosagem compreendendo antagonista de opioide |
| GB9606188D0 (en) * | 1996-03-23 | 1996-05-29 | Danbiosyst Uk | Pollysaccharide microspheres for the pulmonary delivery of drugs |
| EP0811374A1 (en) * | 1996-05-29 | 1997-12-10 | Pfizer Inc. | Combination dosage form comprising cetirizine and pseudoephedrine |
| US5858531A (en) * | 1996-10-24 | 1999-01-12 | Bio Syntech | Method for preparation of polymer microparticles free of organic solvent traces |
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| CN1204890C (zh) * | 1997-12-22 | 2005-06-08 | 欧罗赛铁克股份有限公司 | 防止阿片样物质滥用的方法 |
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| FR2774910B1 (fr) * | 1998-02-16 | 2001-09-07 | Ethypharm Lab Prod Ethiques | Microgranules de sulfate de morphine, procede de fabrication et preparations pharmaceutiques |
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| US6480524B1 (en) * | 1999-09-13 | 2002-11-12 | Nortel Networks Limited | Multiple beam antenna |
| AR031682A1 (es) * | 1999-11-19 | 2003-10-01 | Reckitt Benckiser Helthcare Uk | Composiciones farmaceuticas |
| SI1299104T1 (sl) * | 2000-02-08 | 2009-10-31 | Euro Celtique Sa | Oralne formulacije opioidnih agonistov, varne pred zlorabo |
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| BRPI0418427A (pt) * | 2004-01-30 | 2007-06-12 | Pfizer Italia Srl | formulações farmacêuticas de matriz semi-sólida |
| ES2246694B1 (es) | 2004-04-29 | 2007-05-01 | Instituto Cientifico Y Tecnologico De Navarra, S.A. | Nanoparticulas pegiladas. |
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| PL2197429T3 (pl) * | 2007-09-03 | 2016-09-30 | Kompozycje w postaci cząstek do dostarczania słabo rozpuszczalnych leków |
-
2008
- 2008-09-02 PL PL08829074.7T patent/PL2197429T3/pl unknown
- 2008-09-02 EP EP16163685.7A patent/EP3064198A1/en not_active Withdrawn
- 2008-09-02 ES ES08829074T patent/ES2572157T3/es active Active
- 2008-09-02 EP EP08829074.7A patent/EP2197429B9/en not_active Not-in-force
- 2008-09-02 DK DK08829074.7T patent/DK2197429T3/en active
- 2008-09-02 WO PCT/US2008/010318 patent/WO2009032246A2/en not_active Ceased
- 2008-09-02 KR KR1020107007177A patent/KR101545874B1/ko not_active Expired - Fee Related
- 2008-09-02 JP JP2010522977A patent/JP2010537989A/ja active Pending
- 2008-09-02 AU AU2008296971A patent/AU2008296971B2/en not_active Ceased
- 2008-09-02 US US12/202,881 patent/US8377479B2/en active Active - Reinstated
- 2008-09-02 SI SI200831607A patent/SI2197429T1/sl unknown
- 2008-09-02 HU HUE08829074A patent/HUE027537T2/en unknown
- 2008-09-02 MX MX2010002409A patent/MX2010002409A/es active IP Right Grant
- 2008-09-02 CA CA2699172A patent/CA2699172C/en active Active
-
2013
- 2013-01-15 US US13/741,915 patent/US9554996B2/en active Active
-
2016
- 2016-12-23 HK HK16114657.7A patent/HK1226306A1/en unknown
-
2017
- 2017-01-26 US US15/416,672 patent/US20170143698A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3064198A1 (en) | 2016-09-07 |
| US20090061011A1 (en) | 2009-03-05 |
| AU2008296971B2 (en) | 2014-10-02 |
| ES2572157T3 (es) | 2016-05-30 |
| EP2197429A2 (en) | 2010-06-23 |
| WO2009032246A3 (en) | 2009-04-23 |
| US20170143698A1 (en) | 2017-05-25 |
| KR20100063106A (ko) | 2010-06-10 |
| US8377479B2 (en) | 2013-02-19 |
| HK1226306A1 (en) | 2017-09-29 |
| EP2197429B9 (en) | 2016-10-26 |
| US9554996B2 (en) | 2017-01-31 |
| SI2197429T1 (sl) | 2016-09-30 |
| JP2010537989A (ja) | 2010-12-09 |
| KR101545874B1 (ko) | 2015-08-20 |
| HUE027537T2 (en) | 2016-10-28 |
| CA2699172C (en) | 2016-05-17 |
| DK2197429T3 (en) | 2016-05-30 |
| WO2009032246A2 (en) | 2009-03-12 |
| AU2008296971A1 (en) | 2009-03-12 |
| PL2197429T3 (pl) | 2016-09-30 |
| US20130129828A1 (en) | 2013-05-23 |
| EP2197429B1 (en) | 2016-04-20 |
| CA2699172A1 (en) | 2009-03-12 |
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