MX2009013828A - Composiciones terapeuticas y su uso. - Google Patents

Composiciones terapeuticas y su uso.

Info

Publication number
MX2009013828A
MX2009013828A MX2009013828A MX2009013828A MX2009013828A MX 2009013828 A MX2009013828 A MX 2009013828A MX 2009013828 A MX2009013828 A MX 2009013828A MX 2009013828 A MX2009013828 A MX 2009013828A MX 2009013828 A MX2009013828 A MX 2009013828A
Authority
MX
Mexico
Prior art keywords
therapeutic compositions
pharmaceutically acceptable
acceptable salt
compositions
coadministering
Prior art date
Application number
MX2009013828A
Other languages
English (en)
Spanish (es)
Inventor
Brian P Kearney
Anita A Mathias
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of MX2009013828A publication Critical patent/MX2009013828A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MX2009013828A 2007-06-29 2008-06-26 Composiciones terapeuticas y su uso. MX2009013828A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94732507P 2007-06-29 2007-06-29
PCT/US2008/068351 WO2009006203A1 (en) 2007-06-29 2008-06-26 Therapeutic compositions and the use thereof

Publications (1)

Publication Number Publication Date
MX2009013828A true MX2009013828A (es) 2010-03-10

Family

ID=39817166

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009013828A MX2009013828A (es) 2007-06-29 2008-06-26 Composiciones terapeuticas y su uso.

Country Status (21)

Country Link
US (4) US20090093482A1 (enExample)
EP (1) EP2167089A1 (enExample)
JP (3) JP5547067B2 (enExample)
KR (1) KR20100028656A (enExample)
CN (2) CN101743004A (enExample)
AP (1) AP2490A (enExample)
AR (1) AR067184A1 (enExample)
AU (1) AU2008270634B2 (enExample)
BR (1) BRPI0813955A2 (enExample)
CA (1) CA2691736A1 (enExample)
CO (1) CO6251236A2 (enExample)
EA (1) EA200971096A1 (enExample)
EC (1) ECSP109889A (enExample)
IL (1) IL202745A0 (enExample)
MX (1) MX2009013828A (enExample)
NZ (1) NZ582089A (enExample)
SG (1) SG182228A1 (enExample)
TW (1) TW200916103A (enExample)
UA (1) UA103881C2 (enExample)
WO (1) WO2009006203A1 (enExample)
ZA (1) ZA201000468B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160074018A (ko) * 2005-12-30 2016-06-27 길리애드 사이언시즈, 인코포레이티드 Ｈｉｖ 인테그라제 억제제의 약동학을 개선하기 위한 방법
HRP20150744T4 (hr) 2006-07-07 2024-09-27 Gilead Sciences, Inc. Modulatori farmakokinetičkih svojstava lijekova
PT2069280E (pt) 2006-09-12 2015-06-08 Gilead Sciences Inc Processo e intermediários para preparar inibidores de integrase de vih
PT2487166T (pt) * 2007-02-23 2016-10-17 Gilead Sciences Inc Moduladores de propriedades farmacocinéticas de agentes terapêuticos
TW200914011A (en) * 2007-06-29 2009-04-01 Gilead Sciences Inc Therapeutic compositions and methods
AR068403A1 (es) 2007-09-11 2009-11-18 Gilead Sciences Inc Proceso e intermediarios para la preparacion de inhibidores de integrasa
EP2296633B1 (en) 2008-05-02 2015-09-30 Gilead Sciences, Inc. The use of solid carrier particles to improve the processability of a pharmaceutical agent
US20130203759A1 (en) * 2010-04-09 2013-08-08 Faranak Nikfar ATAZANAVIR SULFATE FORMULATIONS WITH IMPROVED pH EFFECT
US20130274254A1 (en) * 2010-12-21 2013-10-17 Gilead Sciences, Inc. Inhibitors of cytochrome p450 (cyp3a4)
CN107898790B (zh) 2011-11-30 2024-06-21 埃默里大学 用于治疗或预防逆转录病毒和其它病毒感染的抗病毒jak抑制剂
EP2819644A1 (en) * 2012-03-01 2015-01-07 Gilead Sciences, Inc. Spray dried formulations
KR20150040340A (ko) 2012-08-03 2015-04-14 길리애드 사이언시즈, 인코포레이티드 인테그라아제 저해제 제조를 위한 방법 및 중간체
AU2013361401C1 (en) 2012-12-21 2018-08-09 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
NO2865735T3 (enExample) 2013-07-12 2018-07-21
EP3252058B1 (en) 2013-07-12 2021-01-20 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their use for the treatment of hiv infections
TWI744723B (zh) 2014-06-20 2021-11-01 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
NO2717902T3 (enExample) 2014-06-20 2018-06-23
TWI738321B (zh) 2014-12-23 2021-09-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
SMT202100592T1 (it) 2014-12-26 2021-11-12 Univ Emory Derivati antivirali della n4-idrossicitidina
ES2718410T3 (es) 2015-04-02 2019-07-01 Gilead Sciences Inc Compuestos de carbamoilpiridonas policíclicos y su utilización farmacéutica
KR20240011880A (ko) 2017-12-07 2024-01-26 에모리 유니버시티 N4-하이드록시사이티딘 및 유도체 및 이와 관련된 항-바이러스 용도

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552558A (en) * 1989-05-23 1996-09-03 Abbott Laboratories Retroviral protease inhibiting compounds
GB8927913D0 (en) * 1989-12-11 1990-02-14 Hoffmann La Roche Amino acid derivatives
US5413999A (en) * 1991-11-08 1995-05-09 Merck & Co., Inc. HIV protease inhibitors useful for the treatment of AIDS
US5484926A (en) * 1993-10-07 1996-01-16 Agouron Pharmaceuticals, Inc. HIV protease inhibitors
US5914332A (en) * 1995-12-13 1999-06-22 Abbott Laboratories Retroviral protease inhibiting compounds
US5849911A (en) * 1996-04-22 1998-12-15 Novartis Finance Corporation Antivirally active heterocyclic azahexane derivatives
US6087383A (en) * 1998-01-20 2000-07-11 Bristol-Myers Squibb Company Bisulfate salt of HIV protease inhibitor
CA2470365C (en) * 2002-11-20 2011-05-17 Japan Tobacco Inc. 4-oxoquinoline compound and use thereof as hiv integrase inhibitor
US20060111933A1 (en) * 2003-10-09 2006-05-25 Steven Wheeler Adaptive medical decision support system
MY134672A (en) * 2004-05-20 2007-12-31 Japan Tobacco Inc Stable crystal of 4-oxoquinoline compound
EP3287130A1 (en) * 2004-05-21 2018-02-28 Japan Tobacco Inc. Combinations comprising a 4-isoquinolone derivative and protease inhibitors
US20060058286A1 (en) * 2004-09-16 2006-03-16 Mark Krystal Methods of treating HIV infection
US20090233964A1 (en) * 2005-12-30 2009-09-17 Gilead Sciences, Inc. Methods for improving the pharmacokinetics of hiv integrase inhibitors
KR20160074018A (ko) * 2005-12-30 2016-06-27 길리애드 사이언시즈, 인코포레이티드 Ｈｉｖ 인테그라제 억제제의 약동학을 개선하기 위한 방법
WO2007092802A1 (en) * 2006-02-09 2007-08-16 Boehringer Ingelheim International Gmbh Method for treating hiv infection through co-administration of tipranavir and gs 9137
HRP20150744T4 (hr) * 2006-07-07 2024-09-27 Gilead Sciences, Inc. Modulatori farmakokinetičkih svojstava lijekova
PT2069280E (pt) * 2006-09-12 2015-06-08 Gilead Sciences Inc Processo e intermediários para preparar inibidores de integrase de vih
TW200914011A (en) * 2007-06-29 2009-04-01 Gilead Sciences Inc Therapeutic compositions and methods
AR068403A1 (es) * 2007-09-11 2009-11-18 Gilead Sciences Inc Proceso e intermediarios para la preparacion de inhibidores de integrasa
EP2296633B1 (en) * 2008-05-02 2015-09-30 Gilead Sciences, Inc. The use of solid carrier particles to improve the processability of a pharmaceutical agent
US20110000941A1 (en) * 2009-07-06 2011-01-06 Volk J Patrick Apparatus and System for Carrying a Digital Media Player

Also Published As

Publication number Publication date
UA103881C2 (ru) 2013-12-10
CA2691736A1 (en) 2009-01-08
US20090093482A1 (en) 2009-04-09
US20110009411A1 (en) 2011-01-13
EA200971096A1 (ru) 2010-08-30
AR067184A1 (es) 2009-09-30
NZ582089A (en) 2013-01-25
CO6251236A2 (es) 2011-02-21
AU2008270634A1 (en) 2009-01-08
JP2013199494A (ja) 2013-10-03
KR20100028656A (ko) 2010-03-12
AU2008270634B2 (en) 2014-01-16
CN101743004A (zh) 2010-06-16
WO2009006203A1 (en) 2009-01-08
US20170136000A1 (en) 2017-05-18
TW200916103A (en) 2009-04-16
AP2490A (en) 2012-10-04
IL202745A0 (en) 2010-06-30
EP2167089A1 (en) 2010-03-31
JP2010532373A (ja) 2010-10-07
CN103356622A (zh) 2013-10-23
ZA201000468B (en) 2011-06-29
US20140343062A1 (en) 2014-11-20
SG182228A1 (en) 2012-07-30
JP2015143277A (ja) 2015-08-06
JP5769762B2 (ja) 2015-08-26
BRPI0813955A2 (pt) 2017-05-09
AP2009005083A0 (en) 2009-12-31
ECSP109889A (es) 2010-03-31
JP5547067B2 (ja) 2014-07-09

Similar Documents

Publication Publication Date Title
MX2009013828A (es) Composiciones terapeuticas y su uso.
MX2009013829A (es) Composiciones terapeuticas y su uso.
MX2010002318A (es) Derivados azaindol 2,3-sustituidos para tratar infecciones virales.
MX2010002317A (es) Derivados de indol sustituidos y metodos para su utilizacion.
WO2008127364A3 (en) Antiviral compounds and use thereof
UA102251C2 (ru) Производные аминодигидротиазина как ингибиторы васе для лечения болезни альцгеймера
AU2012358805A8 (en) Pyrazolo[1,5-a]pyrimidines as antiviral agents
MX2010002319A (es) Derivados indolicos 2,3 sustituidos para el tratamiento de infecciones virales.
MX2010005355A (es) Derivados de indol sustituidos con 3-aminosulfonilo y metodos de uso de los mismos.
MX2010002316A (es) Derivados tetraciclicos de indol y su uso para el tratamiento o prevencion de infecciones virales.
BR112013008140A8 (pt) "compostos imidazotriazinona".
TW200740776A (en) N-phenylbenzotriazolyl c-kit inhibitors
EA201070786A1 (ru) Бензофуропиримидиноны
WO2009129246A3 (en) Compositions and methods for preparing and using same
MX2008013196A (es) 5-amido-2-carboxiamida-indoles.
MX2010002735A (es) Envase de titulacion para neramexano y su uso en el tratamiento de un trastorno del oido interno.
WO2011113060A3 (en) Antiviral compounds and methods of use thereof
WO2009071689A3 (de) 5-halogen-substituierte oxindol-derivate und ihre verwendung zur behandlung von vasopressin-abhängigen erkrankungen
IL176142A (en) Processes for preparing montelukast sodium
WO2009114560A3 (en) Compositions and methods for the therapy and diagnosis of cytomegalovirus infections
EA201000039A1 (ru) Фармацевтическая композиция, включающая солифенацин или его фармацевтически приемлемую соль
WO2009114461A3 (en) Angiotensin (1-7) dosage forms and uses thereof
WO2008051539A3 (en) Processes for preparing palonosetron salts
MX2009009490A (es) Profarmacos novedosos.
MX2009006325A (es) Compuestos de heteroaril-heteroarilo como inhibidores de cdk para el tratamiento de cancer, inflamacion e infecciones virales.

Legal Events

Date Code Title Description
FA Abandonment or withdrawal