MX2009008734A - Gamma lactamas para el tratamiento de glaucoma o hipertension intraocular. - Google Patents

Gamma lactamas para el tratamiento de glaucoma o hipertension intraocular.

Info

Publication number
MX2009008734A
MX2009008734A MX2009008734A MX2009008734A MX2009008734A MX 2009008734 A MX2009008734 A MX 2009008734A MX 2009008734 A MX2009008734 A MX 2009008734A MX 2009008734 A MX2009008734 A MX 2009008734A MX 2009008734 A MX2009008734 A MX 2009008734A
Authority
MX
Mexico
Prior art keywords
lactams
glaucoma
gamma
treatment
intraocular pressure
Prior art date
Application number
MX2009008734A
Other languages
English (en)
Spanish (es)
Inventor
David W Old
Vinh X Ngo
Wha Bin Im
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of MX2009008734A publication Critical patent/MX2009008734A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX2009008734A 2007-02-15 2008-02-08 Gamma lactamas para el tratamiento de glaucoma o hipertension intraocular. MX2009008734A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89018107P 2007-02-15 2007-02-15
PCT/US2008/053386 WO2008100809A1 (en) 2007-02-15 2008-02-08 Gamma-lactams for the treatment of glaucoma or elevated intraocular pressure

Publications (1)

Publication Number Publication Date
MX2009008734A true MX2009008734A (es) 2009-08-25

Family

ID=39511007

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009008734A MX2009008734A (es) 2007-02-15 2008-02-08 Gamma lactamas para el tratamiento de glaucoma o hipertension intraocular.

Country Status (12)

Country Link
US (1) US8362054B2 (enExample)
EP (1) EP2118094B1 (enExample)
JP (1) JP5566696B2 (enExample)
KR (1) KR20090109587A (enExample)
CN (1) CN101657445B (enExample)
AU (1) AU2008216499B2 (enExample)
BR (1) BRPI0807600A2 (enExample)
CA (1) CA2678191A1 (enExample)
ES (1) ES2404169T3 (enExample)
MX (1) MX2009008734A (enExample)
NZ (1) NZ598945A (enExample)
WO (1) WO2008100809A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2215084B1 (en) * 2007-10-23 2016-09-28 Allergan, Inc. Therapeutic substituted lactams
CA3212825A1 (en) * 2021-03-08 2022-09-15 Abionyx Pharma Sa Compounds useful for treating liver diseases

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004521954A (ja) * 2001-07-16 2004-07-22 エフ.ホフマン−ラ ロシュ アーゲー Ep4受容体作用薬としてのプロスタグランジン類似体
KR100437972B1 (ko) * 2001-10-27 2004-07-02 한국과학기술연구원 피롤리디논 유도체, 이의 제조 방법 및 이를 포함하는제약 조성물
AU2003211574A1 (en) * 2002-03-05 2003-09-16 Ono Pharmaceutical Co., Ltd. 8-azaprostaglandin derivative compounds and drugs containing the compounds as the active ingredient
US6573294B1 (en) * 2002-05-14 2003-06-03 Allergan, Inc. 8-azaprostaglandin analogs as agents for lowering intraocular pressure
AU2003237520B2 (en) * 2002-06-10 2009-01-08 Laboratoires Serono Sa Gamma lactams as prostaglandin agonists and use thereof
WO2004037813A1 (en) * 2002-10-25 2004-05-06 Merck Frosst Canada & Co. Pyrrolidin-2-on derivatives as ep4 receptor agonists
US7091231B2 (en) * 2004-12-10 2006-08-15 Allergan, Inc. 12-Aryl prostaglandin analogs
JP2008538547A (ja) 2005-03-09 2008-10-30 ロジャー・ウィリアムズ・ホスピタル 甲状腺刺激ホルモン放出ホルモン類縁体及び使用方法
EP1856042B1 (en) 2005-03-10 2012-06-27 Allergan, Inc. Substituted gamma lactams as therapeutic agents
AU2007226957B2 (en) 2006-03-20 2013-08-15 Allergan, Inc. Substituted gamma lactams as prostaglandin EP2 agonists

Also Published As

Publication number Publication date
EP2118094A1 (en) 2009-11-18
EP2118094B1 (en) 2013-04-17
US8362054B2 (en) 2013-01-29
AU2008216499A1 (en) 2008-08-21
KR20090109587A (ko) 2009-10-20
BRPI0807600A2 (pt) 2014-07-22
NZ598945A (en) 2013-08-30
CN101657445B (zh) 2013-06-05
JP2010519208A (ja) 2010-06-03
AU2008216499B2 (en) 2014-04-17
CN101657445A (zh) 2010-02-24
ES2404169T3 (es) 2013-05-24
JP5566696B2 (ja) 2014-08-06
WO2008100809A1 (en) 2008-08-21
CA2678191A1 (en) 2008-08-21
US20100168189A1 (en) 2010-07-01

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Legal Events

Date Code Title Description
FG Grant or registration