MX2009008175A - Metodos para producir vacunas basadas en levadura. - Google Patents

Metodos para producir vacunas basadas en levadura.

Info

Publication number
MX2009008175A
MX2009008175A MX2009008175A MX2009008175A MX2009008175A MX 2009008175 A MX2009008175 A MX 2009008175A MX 2009008175 A MX2009008175 A MX 2009008175A MX 2009008175 A MX2009008175 A MX 2009008175A MX 2009008175 A MX2009008175 A MX 2009008175A
Authority
MX
Mexico
Prior art keywords
improved methods
yeast
based vaccines
producing yeast
neutral
Prior art date
Application number
MX2009008175A
Other languages
English (en)
Inventor
Alex Franzusoff
Deborah Quick
Original Assignee
Globeimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Globeimmune Inc filed Critical Globeimmune Inc
Publication of MX2009008175A publication Critical patent/MX2009008175A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A61K36/064—Saccharomycetales, e.g. baker's yeast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

La invención proporciona los medios para cultivar levaduras a un nivel de pH neutro. Las levaduras cultivadas bajo condiciones de pH neutro muestran características deseables, útiles para fines biológicos, tales como el desarrollo de vacunas, agentes profilácticos y terapéuticos. La invención también proporciona las composiciones y los kits que comprenden las levaduras desarrolladas utilizando las metodologías descritas en la presente.
MX2009008175A 2007-02-02 2008-02-01 Metodos para producir vacunas basadas en levadura. MX2009008175A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89928107P 2007-02-02 2007-02-02
PCT/US2008/052843 WO2008097863A2 (en) 2007-02-02 2008-02-01 Methods for producing yeast-based vaccines

Publications (1)

Publication Number Publication Date
MX2009008175A true MX2009008175A (es) 2009-08-12

Family

ID=39682350

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009008175A MX2009008175A (es) 2007-02-02 2008-02-01 Metodos para producir vacunas basadas en levadura.

Country Status (18)

Country Link
US (2) US9066893B2 (es)
EP (1) EP2121013B1 (es)
JP (2) JP5570819B2 (es)
KR (2) KR20150006022A (es)
CN (2) CN104120086A (es)
AU (1) AU2008214029B2 (es)
BR (1) BRPI0807828B8 (es)
CA (1) CA2676783C (es)
DK (1) DK2121013T3 (es)
ES (1) ES2527756T3 (es)
HK (1) HK1136979A1 (es)
IL (2) IL200176A (es)
MX (1) MX2009008175A (es)
PL (1) PL2121013T3 (es)
PT (1) PT2121013E (es)
SG (2) SG171577A1 (es)
SI (1) SI2121013T1 (es)
WO (1) WO2008097863A2 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
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KR101455222B1 (ko) 2002-12-16 2014-10-31 글로브이뮨 면역 요법으로서의 효모계 백신
EP1809773B1 (en) 2004-10-18 2014-07-16 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis c infection
AU2006268333B2 (en) * 2005-07-11 2012-06-14 Globeimmune, Inc. Compositions and methods for eliciting an immune response to escape mutants of targeted therapies
US20070172503A1 (en) 2005-12-13 2007-07-26 Mycologics,Inc. Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines
WO2007133835A2 (en) 2006-03-27 2007-11-22 Globeimmune, Inc. Ras mutation and compositions and mehods related thereto
WO2008097863A2 (en) * 2007-02-02 2008-08-14 Globeimmune, Inc. Methods for producing yeast-based vaccines
RU2505313C2 (ru) * 2007-03-19 2014-01-27 Глоубиммьюн, Инк. Композиции и способы направленного устранения мутационного ускользания в направленной терапии рака
WO2010033841A1 (en) 2008-09-19 2010-03-25 Globeimmune, Inc. Immunotherapy for chronic hepatitis c virus infection
CA2759013C (en) 2009-04-17 2021-10-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Combination immunotherapy compositions against cancer and methods
EP2477647B1 (en) 2009-09-14 2016-01-13 The Regents of the University of Colorado Modulation of yeast-based immunotherapy products and responses
EP2651439B1 (en) 2010-12-17 2018-09-19 Globeimmune, Inc. Compositions and methods for the treatment or prevention of human adenovirus-36 infection
SG192285A1 (en) 2011-02-12 2013-09-30 Globeimmune Inc Yeast-based therapeutic for chronic hepatitis b infection
PT2685995T (pt) 2011-03-17 2017-08-09 Globeimmune Inc Composições imunoterapêuticas de levedura-brachyury
AU2012271625B2 (en) 2011-06-14 2017-05-18 Globeimmune, Inc. Yeast-based compositions and methods for the treatment or prevention of hepatitis delta virus infection
EP2744918A4 (en) 2011-08-17 2015-06-10 Globeimmune Inc IMMUNOTHERAPEUTIC YEAST MUC1 COMPOSITIONS AND USES THEREOF
WO2014003853A1 (en) 2012-06-26 2014-01-03 Biodesix, Inc. Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies
CA2907560C (en) 2013-03-19 2021-12-07 Timothy C. Rodell Yeast-based immunotherapy for chordoma
EP2978449B1 (en) 2013-03-26 2021-09-08 Globeimmune, Inc. Compositions and methods for the treatment or prevention of human immunodeficiency virus infection
WO2015031778A2 (en) 2013-08-30 2015-03-05 Globeimmune, Inc. Compositions and methods for the treatment or prevention of tuberculosis
CA2948803A1 (en) 2014-04-11 2015-10-15 Globeimmune, Inc. Yeast-based immunotherapy and type i interferon sensitivity
US11065313B2 (en) 2015-08-03 2021-07-20 Globeimmune, Inc. Modified yeast-brachyury immunotherapeutic compositions
EP3793576A4 (en) * 2018-05-15 2022-04-06 Globeimmune, Inc. RECOMBINANT YEAST LYSATES FOR INDUCING CELLULAR IMMUNE RESPONSE
CN112334572A (zh) 2018-06-19 2021-02-05 南特细胞公司 Hiv治疗组合物和方法
US20210290708A1 (en) 2018-09-21 2021-09-23 Nantcell, Inc. Methods and compositions for modulating myeloid-derived suppressor cells

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WO2008097863A2 (en) 2007-02-02 2008-08-14 Globeimmune, Inc. Methods for producing yeast-based vaccines
RU2505313C2 (ru) * 2007-03-19 2014-01-27 Глоубиммьюн, Инк. Композиции и способы направленного устранения мутационного ускользания в направленной терапии рака
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WO2010065626A1 (en) 2008-12-02 2010-06-10 Globeimmune, Inc. Genotyping tools, methods and kits
CA2759013C (en) 2009-04-17 2021-10-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Combination immunotherapy compositions against cancer and methods
EP2477647B1 (en) 2009-09-14 2016-01-13 The Regents of the University of Colorado Modulation of yeast-based immunotherapy products and responses
WO2011115914A1 (en) 2010-03-14 2011-09-22 Globeimmune, Inc. Pharmacogenomic and response-guided treatment of infectious disease using yeast-based immunotherapy

Also Published As

Publication number Publication date
US9066893B2 (en) 2015-06-30
AU2008214029A1 (en) 2008-08-14
IL237406A0 (en) 2015-04-30
ES2527756T3 (es) 2015-01-29
US20130309269A1 (en) 2013-11-21
HK1136979A1 (en) 2010-07-16
SG10201405420QA (en) 2014-10-30
AU2008214029B2 (en) 2014-01-30
EP2121013B1 (en) 2014-10-15
JP5570819B2 (ja) 2014-08-13
CN101687030A (zh) 2010-03-31
IL200176A (en) 2015-10-29
DK2121013T3 (en) 2015-01-19
EP2121013A2 (en) 2009-11-25
CN101687030B (zh) 2014-07-02
JP2010517537A (ja) 2010-05-27
BRPI0807828B8 (pt) 2021-05-25
US9549970B2 (en) 2017-01-24
CN104120086A (zh) 2014-10-29
WO2008097863A2 (en) 2008-08-14
PL2121013T3 (pl) 2015-05-29
PT2121013E (pt) 2015-02-04
WO2008097863A3 (en) 2008-11-20
IL200176A0 (en) 2010-04-15
BRPI0807828A2 (pt) 2014-08-05
SI2121013T1 (sl) 2015-02-27
CA2676783C (en) 2016-04-05
KR101555641B1 (ko) 2015-09-24
KR20150006022A (ko) 2015-01-15
JP2014223072A (ja) 2014-12-04
BRPI0807828B1 (pt) 2018-05-29
SG171577A1 (en) 2011-06-29
US20100189749A1 (en) 2010-07-29
CA2676783A1 (en) 2008-08-14
KR20090116757A (ko) 2009-11-11

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