MX2009005579A - Quinazolinas sustituidas. - Google Patents

Quinazolinas sustituidas.

Info

Publication number
MX2009005579A
MX2009005579A MX2009005579A MX2009005579A MX2009005579A MX 2009005579 A MX2009005579 A MX 2009005579A MX 2009005579 A MX2009005579 A MX 2009005579A MX 2009005579 A MX2009005579 A MX 2009005579A MX 2009005579 A MX2009005579 A MX 2009005579A
Authority
MX
Mexico
Prior art keywords
relates
present
platelet lowering
substituted quinazolines
discovery
Prior art date
Application number
MX2009005579A
Other languages
English (en)
Spanish (es)
Inventor
Richard Franklin
Bernard Golding
Original Assignee
Shire Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Llc filed Critical Shire Llc
Publication of MX2009005579A publication Critical patent/MX2009005579A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
MX2009005579A 2006-11-28 2007-11-19 Quinazolinas sustituidas. MX2009005579A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0623750.7A GB0623750D0 (en) 2006-11-28 2006-11-28 Substituted quinazolines
PCT/GB2007/050697 WO2008065444A2 (fr) 2006-11-28 2007-11-19 Quinazolines substituées

Publications (1)

Publication Number Publication Date
MX2009005579A true MX2009005579A (es) 2009-08-12

Family

ID=37671460

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009005579A MX2009005579A (es) 2006-11-28 2007-11-19 Quinazolinas sustituidas.

Country Status (14)

Country Link
EP (1) EP2099802A2 (fr)
JP (1) JP2010511030A (fr)
KR (1) KR20090094268A (fr)
CN (1) CN101558071B (fr)
AR (1) AR064002A1 (fr)
AU (1) AU2007327047B2 (fr)
BR (1) BRPI0719570A2 (fr)
CA (1) CA2670123A1 (fr)
EA (1) EA018259B1 (fr)
GB (1) GB0623750D0 (fr)
IL (1) IL198809A0 (fr)
MX (1) MX2009005579A (fr)
TW (1) TW200838537A (fr)
WO (1) WO2008065444A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8304420B2 (en) 2006-11-28 2012-11-06 Shire Llc Substituted quinazolines for reducing platelet count
GB0808944D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
GB2462022B (en) 2008-06-16 2011-05-25 Biovascular Inc Controlled release compositions of agents that reduce circulating levels of platelets and methods thereof
GB0822970D0 (en) 2008-12-17 2009-01-21 Shire Llc Process for the preparation of anagrelide and analogues
GB201004495D0 (en) 2010-03-18 2010-05-05 Shire Llc Subtituted quinazolines
GB201017783D0 (en) 2010-10-21 2010-12-01 Shire Llc Process for the preparation of anagrelide and analogues thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7807507A (nl) * 1977-07-25 1979-01-29 Hoffmann La Roche Tricyclische verbindingen.
CA1131631A (fr) * 1979-06-20 1982-09-14 Madhukar S. Chodnekar Derives de la quinazoline et preparations pharmaceutiques
ZA803535B (en) * 1979-06-20 1981-06-24 Hoffmann La Roche Novel quinazoline derivatives and pharmaceutical preparations
CN1738623A (zh) * 2003-01-23 2006-02-22 夏尔控股公司 治疗血小板增多症的制剂和方法
US7700608B2 (en) * 2004-08-04 2010-04-20 Shire Holdings Ag Quinazoline derivatives and their use in the treatment of thrombocythemia
US20060030574A1 (en) * 2004-08-04 2006-02-09 Shire Holdings Ag Quinazoline derivatives useful for the treatment of peripheral arterial disease and as phosphodiesterase inhibitors

Also Published As

Publication number Publication date
IL198809A0 (en) 2010-02-17
AU2007327047A1 (en) 2008-06-05
WO2008065444A3 (fr) 2008-07-31
CN101558071A (zh) 2009-10-14
EA200900740A1 (ru) 2010-02-26
CA2670123A1 (fr) 2008-06-05
KR20090094268A (ko) 2009-09-04
CN101558071B (zh) 2013-04-24
AR064002A1 (es) 2009-03-04
EA018259B1 (ru) 2013-06-28
GB0623750D0 (en) 2007-01-10
WO2008065444A2 (fr) 2008-06-05
TW200838537A (en) 2008-10-01
AU2007327047B2 (en) 2012-08-30
EP2099802A2 (fr) 2009-09-16
BRPI0719570A2 (pt) 2013-12-10
JP2010511030A (ja) 2010-04-08
WO2008065444B1 (fr) 2008-10-09

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Legal Events

Date Code Title Description
HH Correction or change in general