MX2009005444A - Sistema de suministro para un farmaco hidrofilico no esteroide no ionizado. - Google Patents

Sistema de suministro para un farmaco hidrofilico no esteroide no ionizado.

Info

Publication number
MX2009005444A
MX2009005444A MX2009005444A MX2009005444A MX2009005444A MX 2009005444 A MX2009005444 A MX 2009005444A MX 2009005444 A MX2009005444 A MX 2009005444A MX 2009005444 A MX2009005444 A MX 2009005444A MX 2009005444 A MX2009005444 A MX 2009005444A
Authority
MX
Mexico
Prior art keywords
steroidal
delivery system
hydrophilic drug
vinyl acetate
polymer
Prior art date
Application number
MX2009005444A
Other languages
English (en)
Inventor
Wouter De Graaff
Armin Szegedi
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of MX2009005444A publication Critical patent/MX2009005444A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Esta invención se refiere a una formulación de liberación prolongada que contiene un fármaco sólido hidrofílico no esteroide no ionizado, que tiene un peso molecular por debajo de 500 Dalton y que tiene una solubilidad de al menos 0.1% por peso en copolímero de acetato de vinilo y etileno que tiene un contenido de acetato de vinilo de 28%, cuya formulación es un dispositivo vaginal que tiene una piel y cuyo dispositivo comprende un compartimiento interior elaborado de un polímero termoplástico, cuyo polímero contiene el fármaco. El polímero preferiblemente está elaborado de copolímero de etileno y acetato de vinilo.
MX2009005444A 2006-11-22 2007-11-21 Sistema de suministro para un farmaco hidrofilico no esteroide no ionizado. MX2009005444A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06124598 2006-11-22
PCT/EP2007/062626 WO2008062008A1 (en) 2006-11-22 2007-11-21 Delivery system for a non-steroidal non-ionized hydrophilic drug

Publications (1)

Publication Number Publication Date
MX2009005444A true MX2009005444A (es) 2009-06-02

Family

ID=37898528

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2009005444A MX2009005444A (es) 2006-11-22 2007-11-21 Sistema de suministro para un farmaco hidrofilico no esteroide no ionizado.
MX2009005445A MX2009005445A (es) 2006-11-22 2007-11-21 Sistema de suministro para risperidona.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2009005445A MX2009005445A (es) 2006-11-22 2007-11-21 Sistema de suministro para risperidona.

Country Status (6)

Country Link
US (2) US20100203104A1 (es)
EP (2) EP2094270A1 (es)
JP (2) JP2010510287A (es)
CA (2) CA2670454A1 (es)
MX (2) MX2009005444A (es)
WO (2) WO2008062008A1 (es)

Families Citing this family (20)

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Publication number Priority date Publication date Assignee Title
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
CA2437639C (en) 2003-08-11 2016-07-05 Valera Pharmaceuticals, Inc. Long term drug delivery devices with polyurethane based polymers and their manufacture
US7858110B2 (en) 2003-08-11 2010-12-28 Endo Pharmaceuticals Solutions, Inc. Long term drug delivery devices with polyurethane based polymers and their manufacture
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
GB0613333D0 (en) * 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) * 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
CA2657533A1 (en) * 2006-07-12 2008-01-17 Controlled Therapeutics (Scotland) Ltd. Drug delivery polymer with hydrochloride salt of clindamycin
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
WO2008062008A1 (en) * 2006-11-22 2008-05-29 N.V. Organon Delivery system for a non-steroidal non-ionized hydrophilic drug
WO2009129459A1 (en) * 2008-04-18 2009-10-22 Combinent Biomedical Systems, Inc. Devices that include ethylene-vinyl acetate copolymers and methods of making and using same
WO2010039722A1 (en) * 2008-09-30 2010-04-08 Endo Pharmaceuticals Solutions Inc. Implantable device for the delivery of risperidone and methods of use thereof
JP5869551B2 (ja) 2010-03-16 2016-02-24 タイタン ファーマシューティカルズ インコーポレイテッド 薬物送達のための不均一な埋め込み型デバイス
US20170319833A1 (en) * 2010-03-28 2017-11-09 Evestra, Inc. Intravaginal drug delivery device
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
DE102013011399A1 (de) 2012-07-31 2014-02-06 Amw Gmbh Implantat mit Risperidon
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
AU2019275409B2 (en) 2018-05-24 2024-08-15 Celanese Eva Performance Polymers Llc Implantable device for sustained release of a macromolecular drug compound
US11689849B2 (en) 2018-05-24 2023-06-27 Nureva, Inc. Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones
CN111971026A (zh) 2018-05-24 2020-11-20 塞拉尼斯伊娃高性能聚合物公司 用于持续释放大分子药物化合物的可植入器件

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016251A (en) * 1972-08-17 1977-04-05 Alza Corporation Vaginal drug dispensing device
US4469671A (en) * 1983-02-22 1984-09-04 Eli Lilly And Company Contraceptive device
GB9326255D0 (en) * 1993-12-23 1994-02-23 Roussel Lab Ltd Medical device for the prevention and treatment of cancer
US6544546B1 (en) * 1995-07-04 2003-04-08 Akzo Nobel, N.V. Ring-shaped devices
US20040044080A1 (en) * 1997-10-28 2004-03-04 Place Virgil A. Treatment of dyspareunia with topically administered nitroglycerin formulations
NZ528377A (en) * 2001-03-27 2005-05-27 Galen Chemicals Ltd Intravaginal drug delivery devices for the administration of an antimicrobial agent
US6887270B2 (en) * 2002-02-08 2005-05-03 Boston Scientific Scimed, Inc. Implantable or insertable medical device resistant to microbial growth and biofilm formation
US20040043171A1 (en) * 2002-08-30 2004-03-04 Audett Jay Douglas Multilaminate backing construction
EP2633853A1 (en) * 2004-01-12 2013-09-04 The Trustees of The University of Pennsylvania Long-term delivery formulations and methods of use thereof
CN100531800C (zh) * 2004-03-24 2009-08-26 奥尔加侬股份有限公司 基于聚乙烯乙酸乙烯酯共聚物的药物递送系统
JP5244394B2 (ja) * 2004-11-10 2013-07-24 トルマー セラピューティクス， インコーポレイテッド． 安定化されたポリマー送達系
CA2669833A1 (en) * 2006-11-22 2008-05-29 N.V. Organon Vaginal delivery system for mirtazapine
WO2008062008A1 (en) * 2006-11-22 2008-05-29 N.V. Organon Delivery system for a non-steroidal non-ionized hydrophilic drug

Also Published As

Publication number Publication date
CA2670157A1 (en) 2008-05-29
EP2094348A1 (en) 2009-09-02
WO2008062009A1 (en) 2008-05-29
CA2670454A1 (en) 2008-05-29
JP2010510286A (ja) 2010-04-02
US20100203104A1 (en) 2010-08-12
EP2094270A1 (en) 2009-09-02
WO2008062008A1 (en) 2008-05-29
JP2010510287A (ja) 2010-04-02
US20100104619A1 (en) 2010-04-29
MX2009005445A (es) 2009-06-02

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