MX2009005444A - Sistema de suministro para un farmaco hidrofilico no esteroide no ionizado. - Google Patents

Sistema de suministro para un farmaco hidrofilico no esteroide no ionizado.

Info

Publication number
MX2009005444A
MX2009005444A MX2009005444A MX2009005444A MX2009005444A MX 2009005444 A MX2009005444 A MX 2009005444A MX 2009005444 A MX2009005444 A MX 2009005444A MX 2009005444 A MX2009005444 A MX 2009005444A MX 2009005444 A MX2009005444 A MX 2009005444A
Authority
MX
Mexico
Prior art keywords
steroidal
delivery system
hydrophilic drug
vinyl acetate
polymer
Prior art date
Application number
MX2009005444A
Other languages
English (en)
Inventor
Wouter De Graaff
Armin Szegedi
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of MX2009005444A publication Critical patent/MX2009005444A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Esta invención se refiere a una formulación de liberación prolongada que contiene un fármaco sólido hidrofílico no esteroide no ionizado, que tiene un peso molecular por debajo de 500 Dalton y que tiene una solubilidad de al menos 0.1% por peso en copolímero de acetato de vinilo y etileno que tiene un contenido de acetato de vinilo de 28%, cuya formulación es un dispositivo vaginal que tiene una piel y cuyo dispositivo comprende un compartimiento interior elaborado de un polímero termoplástico, cuyo polímero contiene el fármaco. El polímero preferiblemente está elaborado de copolímero de etileno y acetato de vinilo.
MX2009005444A 2006-11-22 2007-11-21 Sistema de suministro para un farmaco hidrofilico no esteroide no ionizado. MX2009005444A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06124598 2006-11-22
PCT/EP2007/062626 WO2008062008A1 (en) 2006-11-22 2007-11-21 Delivery system for a non-steroidal non-ionized hydrophilic drug

Publications (1)

Publication Number Publication Date
MX2009005444A true MX2009005444A (es) 2009-06-02

Family

ID=37898528

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2009005445A MX2009005445A (es) 2006-11-22 2007-11-21 Sistema de suministro para risperidona.
MX2009005444A MX2009005444A (es) 2006-11-22 2007-11-21 Sistema de suministro para un farmaco hidrofilico no esteroide no ionizado.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2009005445A MX2009005445A (es) 2006-11-22 2007-11-21 Sistema de suministro para risperidona.

Country Status (6)

Country Link
US (2) US20100104619A1 (es)
EP (2) EP2094270A1 (es)
JP (2) JP2010510286A (es)
CA (2) CA2670454A1 (es)
MX (2) MX2009005445A (es)
WO (2) WO2008062009A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
US7858110B2 (en) * 2003-08-11 2010-12-28 Endo Pharmaceuticals Solutions, Inc. Long term drug delivery devices with polyurethane based polymers and their manufacture
CA2437639C (en) * 2003-08-11 2016-07-05 Valera Pharmaceuticals, Inc. Long term drug delivery devices with polyurethane based polymers and their manufacture
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) * 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
EP2037938A2 (en) * 2006-07-12 2009-03-25 Controlled Therapeutics (Scotland) Ltd. Drug delivery polymer with hydrochloride salt of clindamycin
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
JP2010510286A (ja) * 2006-11-22 2010-04-02 ナームローゼ・フエンノートチヤツプ・オルガノン 非ステロイド非イオン化親水性薬物の送達系
WO2009129459A1 (en) * 2008-04-18 2009-10-22 Combinent Biomedical Systems, Inc. Devices that include ethylene-vinyl acetate copolymers and methods of making and using same
BRPI0919465A2 (pt) * 2008-09-30 2015-12-01 Endo Pharmaceuticals Solutions dispositivo implantável para a liberação de risperidona e métodos de uso do mesmo
RS58011B1 (sr) 2010-03-16 2019-02-28 Titan Pharmaceuticals Inc Heterogena implantabilna sredstva za isporuku lekova
US20170319833A1 (en) * 2010-03-28 2017-11-09 Evestra, Inc. Intravaginal drug delivery device
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
DE102013011399A1 (de) 2012-07-31 2014-02-06 Amw Gmbh Implantat mit Risperidon
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US10406336B2 (en) * 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
CN111971026A (zh) 2018-05-24 2020-11-20 塞拉尼斯伊娃高性能聚合物公司 用于持续释放大分子药物化合物的可植入器件
SG11202005949UA (en) 2018-05-24 2020-07-29 Celanese Eva Performance Polymers Corp Implantable device for sustained release of a macromolecular drug compound

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016251A (en) * 1972-08-17 1977-04-05 Alza Corporation Vaginal drug dispensing device
US4469671A (en) * 1983-02-22 1984-09-04 Eli Lilly And Company Contraceptive device
GB9326255D0 (en) * 1993-12-23 1994-02-23 Roussel Lab Ltd Medical device for the prevention and treatment of cancer
ES2166894T3 (es) * 1995-07-04 2002-05-01 Akzo Nobel Nv Dispositivos anulares.
US20040044080A1 (en) * 1997-10-28 2004-03-04 Place Virgil A. Treatment of dyspareunia with topically administered nitroglycerin formulations
CN1536986B (zh) * 2001-03-27 2012-07-04 沃纳奇尔科特(爱尔兰)有限公司 用于抗微生物剂给药的阴道内药物递送装置
US6887270B2 (en) * 2002-02-08 2005-05-03 Boston Scientific Scimed, Inc. Implantable or insertable medical device resistant to microbial growth and biofilm formation
US20040043171A1 (en) * 2002-08-30 2004-03-04 Audett Jay Douglas Multilaminate backing construction
CA2553254C (en) * 2004-01-12 2013-12-17 The Trustees Of The University Of Pennsylvania Long-term delivery formulations and methods of use thereof
EP1732520B1 (en) * 2004-03-24 2009-06-24 N.V. Organon Drug delivery system based on polyethylene vinylacetate copolymers
EP1824460B1 (en) * 2004-11-10 2014-12-24 Tolmar Therapeutics, Inc. A stabilized polymeric delivery system
JP2010510286A (ja) * 2006-11-22 2010-04-02 ナームローゼ・フエンノートチヤツプ・オルガノン 非ステロイド非イオン化親水性薬物の送達系
JP2010510290A (ja) * 2006-11-22 2010-04-02 ナームローゼ・フエンノートチヤツプ・オルガノン ミルタザピンのための膣送達系

Also Published As

Publication number Publication date
CA2670454A1 (en) 2008-05-29
JP2010510286A (ja) 2010-04-02
MX2009005445A (es) 2009-06-02
EP2094348A1 (en) 2009-09-02
US20100203104A1 (en) 2010-08-12
WO2008062008A1 (en) 2008-05-29
EP2094270A1 (en) 2009-09-02
US20100104619A1 (en) 2010-04-29
CA2670157A1 (en) 2008-05-29
WO2008062009A1 (en) 2008-05-29
JP2010510287A (ja) 2010-04-02

Similar Documents

Publication Publication Date Title
MX2009005444A (es) Sistema de suministro para un farmaco hidrofilico no esteroide no ionizado.
JP2010510286A5 (es)
Almeida et al. Pluronic® F-127 and Pluronic Lecithin Organogel (PLO): main features and their applications in topical and transdermal administration of drugs
WO2006013374A3 (en) Polymeric medical devices for the control of microbial infections
WO2004112748A3 (en) Rate controlled release of a pharmaceutical agent in a biodegradable device
WO2008129106A3 (es) Nanopartículas que comprenden una ciclodextrina y una molécula biológicamente activa y sus aplicaciones
WO2008100576A3 (en) Sustained delivery formulations of rapamycin compounds
WO2008100375A3 (en) Polymer-based films and drug delivery systems made therefrom
MX2019003443A (es) Peliculas permeables con propiedades de barrera microbiana.
MXPA05013138A (es) Composiciones adhesivas, articulos que incorporan las mismas y metodos de manufactura de las mismas.
MX337286B (es) Formulaciones de transferencia sostenida de compuestos de risperidona.
NZ601200A (en) Pharmaceutical dosage forms comprising poly(epsilon-caprolactone)
IL223488A (en) Injectable flow bar preparation containing buprenorphine
WO2010005723A3 (en) Drug loaded polymeric nanoparticles and methods of making and using same
WO2011079279A3 (en) Nanoconjugates and nanoconjugate formulations
BRPI0414017A (pt) pró-fármacos poliméricos de múltiplos braços
WO2012016287A3 (en) Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
HK1148216A1 (en) Active targeting type polymeric micelle carrying drug enclosed therein and medicinal composition
WO2005099667A3 (en) Drug delivery compositions
WO2007041584A3 (en) Implantable sensors, implantable pumps, and anti-scarring drug combinations
WO2009039262A3 (en) Steroid containing ophthalmic drug delivery systems
MY170471A (en) Nonaqueous extrudable composition
WO2008094834A3 (en) Multi-functional drug carriers
PL2029121T3 (pl) Transdermalny system terapeutyczny zawierający cząstki substancji czynnej, o zwiększonym przepływie substancji czynnej
MX347056B (es) Composiciones farmaceuticas.

Legal Events

Date Code Title Description
HH Correction or change in general
FA Abandonment or withdrawal