MX2008006005A - Propiedades inmunoestimuladoras de compuestos a base de oligonucleotidos que comprenden dinucleotidos inmunoestimuladores modificados. - Google Patents
Propiedades inmunoestimuladoras de compuestos a base de oligonucleotidos que comprenden dinucleotidos inmunoestimuladores modificados.Info
- Publication number
- MX2008006005A MX2008006005A MX2008006005A MX2008006005A MX2008006005A MX 2008006005 A MX2008006005 A MX 2008006005A MX 2008006005 A MX2008006005 A MX 2008006005A MX 2008006005 A MX2008006005 A MX 2008006005A MX 2008006005 A MX2008006005 A MX 2008006005A
- Authority
- MX
- Mexico
- Prior art keywords
- immunostimulatory oligonucleotide
- immunostimulatory
- oligonucleotide
- oligonucleotides
- tcg
- Prior art date
Links
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- C12N2310/00—Structure or type of the nucleic acid
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2005/042068 WO2007055704A2 (en) | 2005-11-07 | 2005-11-07 | Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2008006005A true MX2008006005A (es) | 2008-10-01 |
Family
ID=38023711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008006005A MX2008006005A (es) | 2005-11-07 | 2005-11-07 | Propiedades inmunoestimuladoras de compuestos a base de oligonucleotidos que comprenden dinucleotidos inmunoestimuladores modificados. |
Country Status (8)
| Country | Link |
|---|---|
| EP (3) | EP2371956A3 (https=) |
| JP (1) | JP5184366B2 (https=) |
| CN (1) | CN101351228A (https=) |
| AT (1) | ATE529511T1 (https=) |
| AU (1) | AU2005338035B2 (https=) |
| CA (1) | CA2628306C (https=) |
| MX (1) | MX2008006005A (https=) |
| WO (1) | WO2007055704A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US7470674B2 (en) * | 2005-11-07 | 2008-12-30 | Idera Pharmaceuticals, Inc. | Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides |
| EP2357231A2 (en) * | 2007-07-09 | 2011-08-17 | Idera Pharmaceuticals, Inc. | Stabilized immune modulatory RNA (SIMRA) compounds |
| KR20100053598A (ko) * | 2007-08-01 | 2010-05-20 | 이데라 파마슈티칼즈, 인코포레이티드 | Ｔｌｒ９의 신규한 합성 효능제 |
| TR201908550T4 (tr) | 2014-06-04 | 2019-07-22 | Exicure Inc | Profilaktik veya terapötik uygulamalar için lipozomal sferik nükleik asitler tarafından immün modülatörlerin çok değerlikli teslimi. |
| US11213593B2 (en) | 2014-11-21 | 2022-01-04 | Northwestern University | Sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates |
| EP3452598A4 (en) | 2016-05-06 | 2020-04-29 | Exicure, Inc. | LIPOSOMAL SPHERICAL NUCLEIC ACID (ANS) CONSTRUCTS HAVING ANTISENSE OLIGONUCLEOTIDES (ASO) FOR THE SPECIFIC INACTIVATION OF INTERLEUKIN 17 RECEPTOR RNA |
| WO2018039629A2 (en) | 2016-08-25 | 2018-03-01 | Northwestern University | Micellar spherical nucleic acids from thermoresponsive, traceless templates |
| US11696954B2 (en) | 2017-04-28 | 2023-07-11 | Exicure Operating Company | Synthesis of spherical nucleic acids using lipophilic moieties |
| WO2018209270A1 (en) | 2017-05-11 | 2018-11-15 | Northwestern University | Adoptive cell therapy using spherical nucleic acids (snas) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5149798A (en) | 1989-04-06 | 1992-09-22 | Worcester Foundation For Experimental Biology | Process for synthesizing oligonucleotides and their analogs adaptable to large scale syntheses |
| US5149797A (en) | 1990-02-15 | 1992-09-22 | The Worcester Foundation For Experimental Biology | Method of site-specific alteration of rna and production of encoded polypeptides |
| US5652355A (en) | 1992-07-23 | 1997-07-29 | Worcester Foundation For Experimental Biology | Hybrid oligonucleotide phosphorothioates |
| TW244371B (https=) | 1992-07-23 | 1995-04-01 | Tri Clover Inc | |
| US6346614B1 (en) | 1992-07-23 | 2002-02-12 | Hybridon, Inc. | Hybrid oligonucleotide phosphorothioates |
| US5912332A (en) | 1996-07-26 | 1999-06-15 | Hybridon, Inc. | Affinity-based purification of oligonucleotides using soluble multimeric oligonucleotides |
| US6426334B1 (en) | 1997-04-30 | 2002-07-30 | Hybridon, Inc. | Oligonucleotide mediated specific cytokine induction and reduction of tumor growth in a mammal |
| EP2314693A3 (en) | 1999-08-13 | 2012-11-28 | Idera Pharmaceuticals, Inc. | Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides |
| CA2398432C (en) | 2000-01-26 | 2012-06-19 | Hybridon, Inc. | Modulation of oligonucleotide cpg-mediated immune stimulation by positional modification of nucleosides |
| WO2003035836A2 (en) * | 2001-10-24 | 2003-05-01 | Hybridon Inc. | Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends |
| CA2512484A1 (en) * | 2003-01-16 | 2004-05-08 | Hybridon, Inc. | Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides |
| US7498425B2 (en) * | 2004-06-15 | 2009-03-03 | Idera Pharmaceuticals, Inc. | Immunostimulatory oligonucleotide multimers |
-
2005
- 2005-11-07 EP EP11001257A patent/EP2371956A3/en not_active Withdrawn
- 2005-11-07 JP JP2008538857A patent/JP5184366B2/ja not_active Expired - Fee Related
- 2005-11-07 AT AT05851907T patent/ATE529511T1/de not_active IP Right Cessation
- 2005-11-07 WO PCT/US2005/042068 patent/WO2007055704A2/en not_active Ceased
- 2005-11-07 CN CNA2005800524843A patent/CN101351228A/zh active Pending
- 2005-11-07 EP EP11003299.2A patent/EP2402442B1/en not_active Expired - Lifetime
- 2005-11-07 MX MX2008006005A patent/MX2008006005A/es active IP Right Grant
- 2005-11-07 CA CA2628306A patent/CA2628306C/en not_active Expired - Fee Related
- 2005-11-07 AU AU2005338035A patent/AU2005338035B2/en not_active Ceased
- 2005-11-07 EP EP05851907A patent/EP1942945B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1942945A2 (en) | 2008-07-16 |
| CA2628306C (en) | 2014-06-17 |
| JP2009514527A (ja) | 2009-04-09 |
| EP2402442B1 (en) | 2013-07-31 |
| EP2371956A2 (en) | 2011-10-05 |
| ATE529511T1 (de) | 2011-11-15 |
| EP2371956A3 (en) | 2012-01-04 |
| AU2005338035A1 (en) | 2007-05-18 |
| AU2005338035B2 (en) | 2012-06-07 |
| EP2402442A3 (en) | 2012-03-28 |
| JP5184366B2 (ja) | 2013-04-17 |
| CA2628306A1 (en) | 2007-05-18 |
| EP2402442A2 (en) | 2012-01-04 |
| CN101351228A (zh) | 2009-01-21 |
| EP1942945A4 (en) | 2009-01-21 |
| EP1942945B1 (en) | 2011-10-19 |
| WO2007055704A3 (en) | 2007-12-06 |
| WO2007055704A2 (en) | 2007-05-18 |
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