MX2007005124A - Composiciones farmaceuticas espontaneamente dispersables. - Google Patents

Composiciones farmaceuticas espontaneamente dispersables.

Info

Publication number
MX2007005124A
MX2007005124A MX2007005124A MX2007005124A MX2007005124A MX 2007005124 A MX2007005124 A MX 2007005124A MX 2007005124 A MX2007005124 A MX 2007005124A MX 2007005124 A MX2007005124 A MX 2007005124A MX 2007005124 A MX2007005124 A MX 2007005124A
Authority
MX
Mexico
Prior art keywords
pharmaceutical compositions
dispersible pharmaceutical
spontaneously dispersible
solid
room temperature
Prior art date
Application number
MX2007005124A
Other languages
English (en)
Inventor
Madhusudhan Pudipeddi
Alan Edward Royce
Ping Li
Abu T M Serajuddin
Barbara Luckel
Sara Royce Hynes
Michael Ambuhl
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2007005124A publication Critical patent/MX2007005124A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Una composicion farmaceutica espontaneamente dispersable, la cual comprende un farmaco pobremente soluble, y un medio de vehiculo que comprende: (1) un componente lipofilico, (2) un tensoactivo, y opcionalmente (3) un componente hidrofilico, en donde cuando menos uno de los componentes (1) a (3) es solido a temperatura ambiente. Un componente hidrofilico particularmente util en el sistema, es un polimero que es solido a temperatura ambiente, por ejemplo PEG solido.
MX2007005124A 2004-10-29 2005-10-27 Composiciones farmaceuticas espontaneamente dispersables. MX2007005124A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62334404P 2004-10-29 2004-10-29
US62334504P 2004-10-29 2004-10-29
PCT/US2005/039004 WO2006050123A1 (en) 2004-10-29 2005-10-27 Spontaneously dispersible pharmaceutical compositions

Publications (1)

Publication Number Publication Date
MX2007005124A true MX2007005124A (es) 2007-06-22

Family

ID=35876536

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007005124A MX2007005124A (es) 2004-10-29 2005-10-27 Composiciones farmaceuticas espontaneamente dispersables.

Country Status (9)

Country Link
US (1) US20080064760A1 (es)
EP (1) EP1807049A1 (es)
JP (1) JP2008518931A (es)
KR (1) KR20070069172A (es)
AU (1) AU2005302501A1 (es)
BR (1) BRPI0518239A2 (es)
CA (1) CA2578854A1 (es)
MX (1) MX2007005124A (es)
WO (1) WO2006050123A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5027885B2 (ja) * 2006-09-26 2012-09-19 サムヤン コーポレイション 水難溶性カンプトテシン誘導体のサブミクロンナノ粒子及びその製造方法
JP2010511722A (ja) * 2006-12-05 2010-04-15 ノバルティス アーゲー バルサルタンのマイクロエマルジョン投与形態およびその製造方法
US20090022727A1 (en) 2007-01-26 2009-01-22 Alza Corp. Injectable, nonaqueous suspension with high concentration of therapeutic agent
CN109745287A (zh) 2010-05-03 2019-05-14 帝国制药美国公司 非水性紫杉烷前-乳剂制剂以及制备和使用该制剂的方法
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
IL131609A0 (en) * 1997-03-12 2001-01-28 Abbott Lab Hydrophilic binary systems for the administration of cyclosporine
ID25908A (id) * 1998-03-06 2000-11-09 Novartis Ag Prakonsentrat-prakonsentrat emulsi yang mengandung siklosporin atau makrolida
US20020102301A1 (en) * 2000-01-13 2002-08-01 Joseph Schwarz Pharmaceutical solid self-emulsifying composition for sustained delivery of biologically active compounds and the process for preparation thereof
US6828301B2 (en) * 2002-02-07 2004-12-07 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for hepatitis C viral protease inhibitors
AU2003295773A1 (en) * 2002-11-21 2004-06-18 Novacea, Inc. Treatment of liver disease with active vitamin d compounds

Also Published As

Publication number Publication date
WO2006050123A1 (en) 2006-05-11
JP2008518931A (ja) 2008-06-05
KR20070069172A (ko) 2007-07-02
EP1807049A1 (en) 2007-07-18
AU2005302501A1 (en) 2006-05-11
CA2578854A1 (en) 2006-05-11
US20080064760A1 (en) 2008-03-13
BRPI0518239A2 (pt) 2008-11-11

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal